Ica1l (islet cell autoantigen 1-like) - Rat Genome Database

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Pathways
Gene: Ica1l (islet cell autoantigen 1-like) Rattus norvegicus
Analyze
Symbol: Ica1l
Name: islet cell autoantigen 1-like
RGD ID: 735110
Description: Predicted to enable membrane curvature sensor activity. Predicted to be involved in membrane bending and regulation of secretion. Predicted to act upstream of or within spermatid development. Predicted to be located in acrosomal vesicle. Predicted to be active in secretory granule membrane. Orthologous to human ICA1L (islet cell autoantigen 1 like); INTERACTS WITH bisphenol A; cadmium dichloride; fenvalerate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein homolog; Ica69-related protein; islet cell autoantigen 1, 69kDa-like; islet cell autoantigen 1-like protein; LOC316432
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,906,148 - 68,964,078 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl968,906,148 - 68,963,692 (-)EnsemblGRCr8
mRatBN7.2961,410,959 - 61,469,884 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx969,914,281 - 69,950,389 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,029,835 - 75,065,943 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,348,547 - 73,384,653 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,788,094 - 66,848,958 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,790,047 - 66,845,403 (-)Ensemblrn6Rnor6.0
Rnor_5.0966,599,967 - 66,659,239 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4958,549,961 - 58,588,146 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera958,848,507 - 58,883,908 (-)NCBICelera
RGSC_v3.1958,696,942 - 58,735,128 (-)NCBI
Cytogenetic Map9q31-q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells. Spitzenberger F, etal., J Biol Chem 2003 Jul 11;278(28):26166-73.
Additional References at PubMed
PMID:26306493  


Genomics

Comparative Map Data
Ica1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,906,148 - 68,964,078 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl968,906,148 - 68,963,692 (-)EnsemblGRCr8
mRatBN7.2961,410,959 - 61,469,884 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx969,914,281 - 69,950,389 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,029,835 - 75,065,943 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,348,547 - 73,384,653 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,788,094 - 66,848,958 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,790,047 - 66,845,403 (-)Ensemblrn6Rnor6.0
Rnor_5.0966,599,967 - 66,659,239 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4958,549,961 - 58,588,146 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera958,848,507 - 58,883,908 (-)NCBICelera
RGSC_v3.1958,696,942 - 58,735,128 (-)NCBI
Cytogenetic Map9q31-q32NCBI
ICA1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,773,176 - 202,871,766 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,773,150 - 202,872,061 (-)Ensemblhg38GRCh38
GRCh372203,637,899 - 203,736,489 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362203,346,118 - 203,444,616 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342203,467,301 - 203,561,871NCBI
Celera2197,390,623 - 197,489,058 (-)NCBICelera
Cytogenetic Map2q33.2NCBI
HuRef2195,484,776 - 195,583,236 (-)NCBIHuRef
CHM1_12203,644,501 - 203,742,964 (-)NCBICHM1_1
T2T-CHM13v2.02203,254,630 - 203,353,223 (-)NCBIT2T-CHM13v2.0
Ica1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39160,024,955 - 60,082,646 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl160,021,649 - 60,082,343 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38159,985,796 - 60,043,481 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,982,490 - 60,043,184 (-)Ensemblmm10GRCm38
MGSCv37160,045,912 - 60,099,931 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36159,933,614 - 59,987,633 (-)NCBIMGSCv36mm8
Celera160,504,490 - 60,558,846 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.45NCBI
Ica1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545712,006,306 - 12,085,799 (+)Ensembl
ChiLan1.0NW_00495545711,983,201 - 12,085,870 (+)NCBIChiLan1.0ChiLan1.0
ICA1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213105,406,392 - 105,475,098 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B105,421,389 - 105,490,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B90,034,205 - 90,105,600 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B208,184,023 - 208,252,084 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B208,184,023 - 208,251,254 (-)EnsemblpanPan2panpan1.1
ICA1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,674,970 - 11,754,931 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,678,125 - 11,741,997 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3712,558,653 - 12,638,491 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03711,611,993 - 11,691,866 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,613,496 - 11,691,338 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,568,391 - 11,648,134 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,539,667 - 11,619,487 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,533,517 - 11,613,396 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ica1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,877,981 - 159,952,434 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,853,868 - 1,902,788 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,853,178 - 1,922,684 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ICA1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15106,295,934 - 106,377,579 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115106,293,936 - 106,377,573 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,753,375 - 117,827,860 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ICA1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11088,492,255 - 88,609,268 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1088,517,716 - 88,569,031 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040110,776,859 - 110,874,196 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ica1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476513,588,073 - 13,687,250 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476513,547,437 - 13,687,641 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ica1l
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v156,320,202 - 6,367,818 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ica1l
420 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:29
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000041546
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
1578659Tspe1Trichinella spiralis expulsion QTL 14.8parasite quantity (VT:0010441)logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)96887549773185088Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
BF413809  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,425,984 - 61,426,090 (+)MAPPERmRatBN7.2
Rnor_6.0966,801,989 - 66,802,094NCBIRnor6.0
Rnor_5.0966,613,858 - 66,613,963UniSTSRnor5.0
RGSC_v3.4958,561,730 - 58,561,835UniSTSRGSC3.4
Celera958,860,276 - 58,860,381UniSTS
RH 3.4 Map9495.8UniSTS
Cytogenetic Map9q31UniSTS
RH133804  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,413,720 - 61,413,940 (+)MAPPERmRatBN7.2
Rnor_6.0966,789,725 - 66,789,944NCBIRnor6.0
Rnor_5.0966,601,594 - 66,601,813UniSTSRnor5.0
RGSC_v3.4958,549,466 - 58,549,685UniSTSRGSC3.4
Celera958,848,012 - 58,848,231UniSTS
RH 3.4 Map9496.3UniSTS
Cytogenetic Map9q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 10 47 161 71 70 39 80 39 6 297 158 11 140 76 92 31 16 16

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_199400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC129370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY491990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041546   ⟹   ENSRNOP00000045103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,906,148 - 68,963,692 (-)Ensembl
mRatBN7.2 Ensembl961,412,091 - 61,450,546 (-)Ensembl
Rnor_6.0 Ensembl966,790,047 - 66,845,403 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094628   ⟹   ENSRNOP00000094417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,908,100 - 68,944,604 (-)Ensembl
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119954   ⟹   ENSRNOP00000076459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,907,273 - 68,963,692 (-)Ensembl
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000135120   ⟹   ENSRNOP00000104337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,907,273 - 68,963,692 (-)Ensembl
RefSeq Acc Id: NM_199400   ⟹   NP_955432
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,692 (-)NCBI
mRatBN7.2961,412,090 - 61,469,638 (-)NCBI
Rnor_6.0966,790,220 - 66,825,834 (-)NCBI
Rnor_5.0966,599,967 - 66,659,239 (-)NCBI
RGSC_v3.4958,549,961 - 58,588,146 (-)RGD
Celera958,848,507 - 58,883,908 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244994   ⟹   XP_006245056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Rnor_5.0966,599,967 - 66,659,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006244995   ⟹   XP_006245057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,517 (-)NCBI
mRatBN7.2961,410,959 - 61,469,467 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Rnor_5.0966,599,967 - 66,659,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006244999   ⟹   XP_006245061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Rnor_5.0966,599,967 - 66,659,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767111   ⟹   XP_008765333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,521 (-)NCBI
mRatBN7.2961,412,088 - 61,469,470 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596461   ⟹   XP_017451950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596464   ⟹   XP_017451953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,964,078 (-)NCBI
mRatBN7.2961,412,088 - 61,469,884 (-)NCBI
Rnor_6.0966,788,094 - 66,848,958 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083634   ⟹   XP_038939562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,520 (-)NCBI
mRatBN7.2961,410,959 - 61,469,470 (-)NCBI
RefSeq Acc Id: XM_039083635   ⟹   XP_038939563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
mRatBN7.2961,410,959 - 61,469,621 (-)NCBI
RefSeq Acc Id: XM_039083636   ⟹   XP_038939564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
RefSeq Acc Id: XM_039083637   ⟹   XP_038939565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
RefSeq Acc Id: XM_039083638   ⟹   XP_038939566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,943,779 (-)NCBI
mRatBN7.2961,410,959 - 61,449,727 (-)NCBI
RefSeq Acc Id: XM_063267202   ⟹   XP_063123272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,519 (-)NCBI
RefSeq Acc Id: XM_063267203   ⟹   XP_063123273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,519 (-)NCBI
RefSeq Acc Id: XM_063267204   ⟹   XP_063123274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267205   ⟹   XP_063123275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,519 (-)NCBI
RefSeq Acc Id: XM_063267206   ⟹   XP_063123276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,737 (-)NCBI
RefSeq Acc Id: XM_063267207   ⟹   XP_063123277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267208   ⟹   XP_063123278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267209   ⟹   XP_063123279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267210   ⟹   XP_063123280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267211   ⟹   XP_063123281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267212   ⟹   XP_063123282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
Protein Sequences
Protein RefSeqs NP_955432 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245056 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245057 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245061 (Get FASTA)   NCBI Sequence Viewer  
  XP_008765333 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451950 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451953 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939562 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939563 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939564 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939565 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939566 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123272 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123273 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123274 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123275 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123276 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123277 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123278 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123279 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123280 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123281 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123282 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAR36901 (Get FASTA)   NCBI Sequence Viewer  
  EDL98942 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045103
  ENSRNOP00000076459
  ENSRNOP00000094417
  ENSRNOP00000104337
GenBank Protein Q6RUG5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_955432   ⟸   NM_199400
- UniProtKB: Q6RUG5 (UniProtKB/Swiss-Prot),   A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245061   ⟸   XM_006244999
- Peptide Label: isoform X13
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245057   ⟸   XM_006244995
- Peptide Label: isoform X4
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL),   A0A8I6AM57 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245056   ⟸   XM_006244994
- Peptide Label: isoform X1
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765333   ⟸   XM_008767111
- Peptide Label: isoform X3
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451953   ⟸   XM_017596464
- Peptide Label: isoform X7
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451950   ⟸   XM_017596461
- Peptide Label: isoform X6
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045103   ⟸   ENSRNOT00000041546
RefSeq Acc Id: XP_038939563   ⟸   XM_039083635
- Peptide Label: isoform X7
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939562   ⟸   XM_039083634
- Peptide Label: isoform X2
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939565   ⟸   XM_039083637
- Peptide Label: isoform X20
RefSeq Acc Id: XP_038939564   ⟸   XM_039083636
- Peptide Label: isoform X16
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939566   ⟸   XM_039083638
- Peptide Label: isoform X21
Ensembl Acc Id: ENSRNOP00000094417   ⟸   ENSRNOT00000094628
Ensembl Acc Id: ENSRNOP00000076459   ⟸   ENSRNOT00000119954
RefSeq Acc Id: XP_063123278   ⟸   XM_063267208
- Peptide Label: isoform X14
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123274   ⟸   XM_063267204
- Peptide Label: isoform X9
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123281   ⟸   XM_063267211
- Peptide Label: isoform X18
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123277   ⟸   XM_063267207
- Peptide Label: isoform X12
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123282   ⟸   XM_063267212
- Peptide Label: isoform X19
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123280   ⟸   XM_063267210
- Peptide Label: isoform X17
- UniProtKB: A0A8I5XZZ8 (UniProtKB/TrEMBL),   A6IPB8 (UniProtKB/TrEMBL),   A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123279   ⟸   XM_063267209
- Peptide Label: isoform X15
- UniProtKB: Q6RUG5 (UniProtKB/Swiss-Prot),   A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123276   ⟸   XM_063267206
- Peptide Label: isoform X11
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123273   ⟸   XM_063267203
- Peptide Label: isoform X8
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123275   ⟸   XM_063267205
- Peptide Label: isoform X10
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123272   ⟸   XM_063267202
- Peptide Label: isoform X5
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000104337   ⟸   ENSRNOT00000135120
Protein Domains
AH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6RUG5-F1-model_v2 AlphaFold Q6RUG5 1-435 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735110 AgrOrtholog
BioCyc Gene G2FUF-27386 BioCyc
Ensembl Genes ENSRNOG00000017258 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000041546 ENTREZGENE
  ENSRNOT00000094628 ENTREZGENE
  ENSRNOT00000119954 ENTREZGENE
  ENSRNOT00000135120 ENTREZGENE
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot
  AH_dom UniProtKB/Swiss-Prot
  Islet_autoAg_Ica1/Ica1-like UniProtKB/Swiss-Prot
  Islet_autoAg_Ica1_C UniProtKB/Swiss-Prot
KEGG Report rno:316432 UniProtKB/Swiss-Prot
NCBI Gene 316432 ENTREZGENE
PANTHER ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN UniProtKB/Swiss-Prot
  PTHR10164 UniProtKB/Swiss-Prot
Pfam Arfaptin UniProtKB/Swiss-Prot
  ICA69 UniProtKB/Swiss-Prot
PhenoGen Ica1l PhenoGen
PROSITE PS50870 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017258 RatGTEx
SMART Arfaptin UniProtKB/Swiss-Prot
  ICA69 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot
UniProt A0A0H2UHX6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5XZZ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AM57 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LRK6_RAT UniProtKB/TrEMBL
  A6IPB8 ENTREZGENE, UniProtKB/TrEMBL
  ICA1L_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Ica1l  islet cell autoantigen 1-like  LOC316432  Ica69-related protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 LOC316432        Symbol and Name status set to provisional 70820 PROVISIONAL