Ica1l (islet cell autoantigen 1 like) - Rat Genome Database

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Gene: Ica1l (islet cell autoantigen 1 like) Ictidomys tridecemlineatus
Analyze
Symbol: Ica1l
Name: islet cell autoantigen 1 like
RGD ID: 12585965
Description: ENCODES a protein that exhibits protein domain specific binding (inferred); INVOLVED IN spermatid development (ortholog); ASSOCIATED WITH autoimmune lymphoproliferative syndrome type 2B (ortholog); Autoimmune Lymphoproliferative Syndrome, Type V (ortholog); common variable immunodeficiency 1 (ortholog); FOUND IN acrosomal vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: islet cell autoantigen 1 like, transcript variant X1; islet cell autoantigen 1 like, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,877,981 - 159,952,434 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,853,868 - 1,902,788 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,853,178 - 1,922,684 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ica1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,877,981 - 159,952,434 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,853,868 - 1,902,788 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,853,178 - 1,922,684 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ICA1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,773,176 - 202,871,766 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,773,150 - 202,871,766 (-)EnsemblGRCh38hg38GRCh38
GRCh372203,637,899 - 203,736,489 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362203,346,118 - 203,444,616 (-)NCBINCBI36Build 36hg18NCBI36
Build 342203,467,301 - 203,561,871NCBI
Celera2197,390,623 - 197,489,058 (-)NCBICelera
Cytogenetic Map2q33.2NCBI
HuRef2195,484,776 - 195,583,236 (-)NCBIHuRef
CHM1_12203,644,501 - 203,742,964 (-)NCBICHM1_1
T2T-CHM13v2.02203,254,630 - 203,353,223 (-)NCBIT2T-CHM13v2.0
Ica1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39160,024,955 - 60,082,646 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl160,021,649 - 60,082,343 (-)EnsemblGRCm39 Ensembl
GRCm38159,985,796 - 60,043,481 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,982,490 - 60,043,184 (-)EnsemblGRCm38mm10GRCm38
MGSCv37160,045,912 - 60,099,931 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36159,933,614 - 59,987,633 (-)NCBIMGSCv36mm8
Celera160,504,490 - 60,558,846 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.45NCBI
Ica1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,906,148 - 68,964,078 (-)NCBIGRCr8
mRatBN7.2961,410,959 - 61,469,884 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,914,281 - 69,950,389 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,029,835 - 75,065,943 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,348,547 - 73,384,653 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,788,094 - 66,848,958 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,790,047 - 66,845,403 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,599,967 - 66,659,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,549,961 - 58,588,146 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,696,942 - 58,735,128 (-)NCBI
Celera958,848,507 - 58,883,908 (-)NCBICelera
Cytogenetic Map9q31-q32NCBI
Ica1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545712,006,306 - 12,085,799 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545711,983,201 - 12,085,870 (+)NCBIChiLan1.0ChiLan1.0
ICA1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213105,406,392 - 105,475,098 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B105,421,389 - 105,490,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B90,034,205 - 90,105,600 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B208,184,023 - 208,252,084 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B208,184,023 - 208,251,254 (-)Ensemblpanpan1.1panPan2
ICA1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,674,970 - 11,754,931 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,678,125 - 11,741,997 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3712,558,653 - 12,638,491 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03711,611,993 - 11,691,866 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,613,496 - 11,691,338 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,568,391 - 11,648,134 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,539,667 - 11,619,487 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,533,517 - 11,613,396 (-)NCBIUU_Cfam_GSD_1.0
ICA1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15106,295,934 - 106,377,579 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115106,293,936 - 106,377,573 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,753,375 - 117,827,860 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ICA1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11088,492,255 - 88,609,268 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1088,517,716 - 88,569,031 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040110,776,859 - 110,874,196 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ica1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476513,588,073 - 13,687,250 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476513,547,437 - 13,687,641 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000009928   ⟹   ENSSTOP00000008906
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367261,853,868 - 1,902,788 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000041781   ⟹   ENSSTOP00000028838
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367261,853,868 - 1,902,788 (-)Ensembl
RefSeq Acc Id: XM_013364587   ⟹   XP_013220041
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303159,877,981 - 159,952,428 (-)NCBI
SpeTri2.0NW_0049367261,853,178 - 1,922,684 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735693   ⟹   XP_021591368
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303159,877,981 - 159,934,206 (-)NCBI
SpeTri2.0NW_0049367261,853,178 - 1,904,492 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040294728   ⟹   XP_040150662
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303159,877,981 - 159,952,434 (-)NCBI
Protein Sequences
Protein RefSeqs XP_013220041 (Get FASTA)   NCBI Sequence Viewer  
  XP_021591368 (Get FASTA)   NCBI Sequence Viewer  
  XP_040150662 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000008906.3
  ENSSTOP00000028838.1
GenBank Protein KAG3275022 (Get FASTA)   NCBI Sequence Viewer  
  KAG3275023 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013220041   ⟸   XM_013364587
- Peptide Label: isoform X1
- UniProtKB: A0A287D5L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591368   ⟸   XM_021735693
- Peptide Label: isoform X1
- UniProtKB: A0A287D5L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040150662   ⟸   XM_040294728
- Peptide Label: isoform X2
- UniProtKB: A0A287D5L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000008906   ⟸   ENSSTOT00000009928
RefSeq Acc Id: ENSSTOP00000028838   ⟸   ENSSTOT00000041781
Protein Domains
AH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009931 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009928.3 UniProtKB/TrEMBL
  ENSSTOT00000041781.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  AH_dom UniProtKB/TrEMBL
  Islet_autoAg_Ica1/Ica1-like UniProtKB/TrEMBL
  Islet_autoAg_Ica1_C UniProtKB/TrEMBL
NCBI Gene Ica1l ENTREZGENE
PANTHER ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN UniProtKB/TrEMBL
  PTHR10164 UniProtKB/TrEMBL
Pfam Arfaptin UniProtKB/TrEMBL
  ICA69 UniProtKB/TrEMBL
PROSITE PS50870 UniProtKB/TrEMBL
SMART Arfaptin UniProtKB/TrEMBL
  ICA69 UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
UniProt A0A287D5L8 ENTREZGENE, UniProtKB/TrEMBL
  I3MEI3_ICTTR UniProtKB/TrEMBL