Decr1 (2,4-dienoyl-CoA reductase 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Decr1 (2,4-dienoyl-CoA reductase 1) Rattus norvegicus
Analyze
Symbol: Decr1
Name: 2,4-dienoyl-CoA reductase 1
RGD ID: 70999
Description: Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity; NADPH binding activity; and identical protein binding activity. Predicted to be involved in fatty acid beta-oxidation and positive regulation of cold-induced thermogenesis. Predicted to be part of catalytic complex. Predicted to be active in mitochondrion. Orthologous to human DECR1 (2,4-dienoyl-CoA reductase 1); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2,4-dienoyl CoA reductase 1, mitochondrial; 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial; 2,4-dienoyl-CoA reductase, mitochondrial; 4-enoyl-CoA reductase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8534,208,195 - 34,236,074 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl534,208,195 - 34,236,033 (-)EnsemblGRCr8
mRatBN7.2529,411,172 - 29,439,054 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl529,411,172 - 29,439,018 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx531,567,474 - 31,595,241 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0533,160,140 - 33,187,907 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0533,120,325 - 33,148,092 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0529,573,893 - 29,601,731 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl529,573,898 - 29,601,748 (-)Ensemblrn6Rnor6.0
Rnor_5.0534,253,236 - 34,280,749 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4530,492,196 - 30,520,172 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera528,616,707 - 28,644,572 (-)NCBICelera
RGSC_v3.1530,492,195 - 30,520,172 (-)NCBI
Cytogenetic Map5q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
actinomycin D  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (EXP)
cadmium acetate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlorotoluron  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (EXP)
farnesol  (ISO)
fenofibrate  (EXP,ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furfural  (ISO)
gemfibrozil  (EXP)
glutathione  (EXP)
GW 4064  (ISO)
GW 7647  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
L-methionine  (ISO)
leflunomide  (EXP)
limonene  (EXP)
methapyrilene  (EXP)
methidathion  (ISO)
methimazole  (EXP)
Muraglitazar  (EXP)
N-nitrosomorpholine  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
niclosamide  (ISO)
nimesulide  (EXP)
nitrofen  (EXP)
nobiletin  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
oleic acid  (ISO)
omeprazole  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenformin  (EXP)
phenobarbital  (EXP)
picrotoxin  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pravastatin  (EXP,ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
Soman  (EXP)
streptozocin  (EXP)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
Tesaglitazar  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (EXP)
vinclozolin  (EXP)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
catalytic complex  (IEA,ISO)
mitochondrion  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. cDNA cloning of rat liver 2,4-dienoyl-CoA reductase. Hirose A, etal., Biochim Biophys Acta 1990 Jul 30;1049(3):346-9.
4. Gene Data Set MGD Curation, June 12, 2002
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis. Miinalainen IJ, etal., PLoS Genet. 2009 Jul;5(7):e1000543. doi: 10.1371/journal.pgen.1000543. Epub 2009 Jul 3.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14651853   PMID:15489334   PMID:15531764   PMID:17636013   PMID:18614015   PMID:21630459   PMID:23376485   PMID:23486364   PMID:26316108   PMID:31505169  


Genomics

Comparative Map Data
Decr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8534,208,195 - 34,236,074 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl534,208,195 - 34,236,033 (-)EnsemblGRCr8
mRatBN7.2529,411,172 - 29,439,054 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl529,411,172 - 29,439,018 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx531,567,474 - 31,595,241 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0533,160,140 - 33,187,907 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0533,120,325 - 33,148,092 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0529,573,893 - 29,601,731 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl529,573,898 - 29,601,748 (-)Ensemblrn6Rnor6.0
Rnor_5.0534,253,236 - 34,280,749 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4530,492,196 - 30,520,172 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera528,616,707 - 28,644,572 (-)NCBICelera
RGSC_v3.1530,492,195 - 30,520,172 (-)NCBI
Cytogenetic Map5q13NCBI
DECR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38890,001,477 - 90,053,633 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl890,001,330 - 90,053,633 (+)Ensemblhg38GRCh38
GRCh37891,013,705 - 91,065,861 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36891,082,756 - 91,133,403 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34891,082,755 - 91,133,403NCBI
Celera887,208,502 - 87,259,149 (+)NCBICelera
Cytogenetic Map8q21.3NCBI
HuRef886,223,894 - 86,274,542 (+)NCBIHuRef
CHM1_1891,054,504 - 91,105,151 (+)NCBICHM1_1
T2T-CHM13v2.0891,125,148 - 91,177,304 (+)NCBIT2T-CHM13v2.0
Decr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39415,917,240 - 15,945,377 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl415,917,240 - 15,945,507 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38415,917,240 - 15,945,377 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl415,917,240 - 15,945,507 (-)Ensemblmm10GRCm38
MGSCv37415,844,387 - 15,872,654 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36415,844,387 - 15,872,654 (-)NCBIMGSCv36mm8
Celera415,720,515 - 15,748,774 (-)NCBICelera
Cytogenetic Map4A2NCBI
cM Map46.66NCBI
Decr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554176,893,231 - 6,931,754 (+)Ensembl
ChiLan1.0NW_0049554176,893,231 - 6,931,754 (+)NCBIChiLan1.0ChiLan1.0
DECR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27107,394,558 - 107,461,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1882,934,216 - 83,001,276 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0886,690,816 - 86,755,379 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1888,642,676 - 88,693,224 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl888,642,172 - 88,693,224 (+)EnsemblpanPan2panpan1.1
DECR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12935,495,348 - 35,544,955 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2935,495,261 - 35,544,955 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2935,646,866 - 35,697,851 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02935,692,661 - 35,742,310 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2935,692,704 - 35,744,794 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12935,684,839 - 35,729,541 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02935,703,896 - 35,747,852 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02936,138,067 - 36,183,640 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Decr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530343,936,906 - 43,975,997 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365443,816,653 - 3,853,632 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365443,816,543 - 3,853,288 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DECR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl446,731,360 - 46,767,422 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1446,731,359 - 46,767,427 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2451,207,727 - 51,243,866 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DECR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1885,086,843 - 85,129,267 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl885,086,874 - 85,129,160 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603955,747,223 - 55,792,311 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Decr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247441,963,825 - 2,003,643 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247441,965,605 - 2,003,299 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Decr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11127,844,877 - 127,872,513 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Decr1
228 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:100
Count of miRNA genes:87
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000011330
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5692228237468560Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)53113042148841739Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_057197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO385941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D00569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011330   ⟹   ENSRNOP00000011330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl534,208,195 - 34,236,033 (-)Ensembl
mRatBN7.2 Ensembl529,411,172 - 29,439,011 (-)Ensembl
Rnor_6.0 Ensembl529,573,898 - 29,601,748 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097769   ⟹   ENSRNOP00000086268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl534,208,195 - 34,236,033 (-)Ensembl
mRatBN7.2 Ensembl529,411,172 - 29,439,011 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119084   ⟹   ENSRNOP00000093824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl529,411,203 - 29,439,018 (-)Ensembl
RefSeq Acc Id: NM_057197   ⟹   NP_476545
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8534,208,195 - 34,236,033 (-)NCBI
mRatBN7.2529,411,172 - 29,439,011 (-)NCBI
Rnor_6.0529,573,893 - 29,601,731 (-)NCBI
Rnor_5.0534,253,236 - 34,280,749 (-)NCBI
RGSC_v3.4530,492,196 - 30,520,172 (-)RGD
Celera528,616,707 - 28,644,572 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109166   ⟹   XP_038965094
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8534,208,203 - 34,236,074 (-)NCBI
mRatBN7.2529,411,180 - 29,439,054 (-)NCBI
RefSeq Acc Id: XM_063287086   ⟹   XP_063143156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8534,209,028 - 34,236,074 (-)NCBI
RefSeq Acc Id: NP_476545   ⟸   NM_057197
- Peptide Label: precursor
- UniProtKB: Q6PCV4 (UniProtKB/Swiss-Prot),   Q64591 (UniProtKB/Swiss-Prot),   G3V734 (UniProtKB/TrEMBL),   A6IIA8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011330   ⟸   ENSRNOT00000011330
RefSeq Acc Id: XP_038965094   ⟸   XM_039109166
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000086268   ⟸   ENSRNOT00000097769
Ensembl Acc Id: ENSRNOP00000093824   ⟸   ENSRNOT00000119084
RefSeq Acc Id: XP_063143156   ⟸   XM_063287086
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64591-F1-model_v2 AlphaFold Q64591 1-335 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693579
Promoter ID:EPDNEW_R4104
Type:multiple initiation site
Name:Decr1_1
Description:2,4-dienoyl-CoA reductase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0529,601,701 - 29,601,761EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70999 AgrOrtholog
BioCyc Gene G2FUF-41863 BioCyc
Ensembl Genes ENSRNOG00000008236 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000011330 ENTREZGENE
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6920489 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
  SDR_fam UniProtKB/Swiss-Prot
KEGG Report rno:117543 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72723 IMAGE-MGC_LOAD
NCBI Gene 117543 ENTREZGENE
PANTHER 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING], MITOCHONDRIAL UniProtKB/Swiss-Prot
  SHORT-CHAIN DEHYDROGENASE/REDUCTASE UniProtKB/Swiss-Prot
Pfam adh_short_C2 UniProtKB/Swiss-Prot
PhenoGen Decr1 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008236 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot
UniProt A0A8I6GDV3_RAT UniProtKB/TrEMBL
  A6IIA8 ENTREZGENE, UniProtKB/TrEMBL
  A6IIA9_RAT UniProtKB/TrEMBL
  DECR_RAT UniProtKB/Swiss-Prot
  G3V734 ENTREZGENE, UniProtKB/TrEMBL
  Q64591 ENTREZGENE
  Q6PCV4 ENTREZGENE
UniProt Secondary Q6PCV4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-12-15 Decr1  2,4-dienoyl-CoA reductase 1  Decr1  2,4-dienoyl CoA reductase 1, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Decr1  2,4-dienoyl CoA reductase 1, mitochondrial      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference