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Gene: Pclo (piccolo (presynaptic cytomatrix protein)) Rattus norvegicus

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Symbol:

Pclo

Name:

piccolo (presynaptic cytomatrix protein)

RGD ID:

69406

Description:

Enables calcium ion binding activity; calcium-dependent phospholipid binding activity; and transcription corepressor binding activity. Involved in several processes, including positive regulation of synaptic vesicle recycling; presynaptic active zone assembly; and regulation of endosome size. Located in several cellular components, including cytoskeleton of presynaptic active zone; distal axon; and rod spherule. Is active in glutamatergic synapse; parallel fiber to Purkinje cell synapse; and presynaptic active zone cytoplasmic component. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 3. Orthologous to human PCLO (piccolo presynaptic cytomatrix protein); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

aczonin; LOC108350654; multidomain presynaptic cytomatrix protein Piccolo; presynaptic cytomatrix protein; protein piccolo; protein piccolo-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

Pclo^{Tn(sb-B-Geo)Fkh}

Genetic Models:

WI.SD-Pclo^{Tn(sb-B-Geo)Fkh}

Latest Assembly:

GRCr8 - GRCr8 Assembly

NCBI Annotation Information:

Note: This gene aligns across a gap in the Rnor_6.0 reference genome assembly, and therefore, the 5' end of this gene was annotated on NW_007905776.1 and the 3' end was annotated on NW_007905775.1 in NCBI's Rattus norvegicus Annotation Release 105. [15 Jun 2015]

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	20,646,604 - 21,005,111 (-)	Ensembl				GRCr8
mRatBN7.2	4	19,691,439 - 20,050,015 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	19,695,315 - 20,049,885 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	24,865,942 - 25,222,133 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	20,697,245 - 21,053,987 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	19,078,298 - 19,437,003 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	16,454,904 - 17,058,921 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	16,454,904 - 17,058,921 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	16,428,814 - 16,661,584 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	4	16,923,700 - 17,031,648 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	15,911,051 - 16,269,090 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	15,219,539 - 15,569,109 (-)	NCBI		Celera
RGSC_v3.1	4	15,911,050 - 16,269,090 (-)	NCBI
Cytogenetic Map	4	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

microcephaly (ISO)

pontocerebellar hypoplasia type 3 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

avobenzone (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (EXP,ISO)

clozapine (ISO)

copper atom (EXP)

copper(0) (EXP)

corosolic acid (ISO)

Cuprizon (ISO)

cyclosporin A (ISO)

DDT (EXP)

dimethylarsinic acid (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP,ISO)

gentamycin (EXP)

ibuprofen (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

nickel atom (ISO)

ozone (ISO)

paracetamol (EXP)

perfluorooctanoic acid (EXP,ISO)

phenylmercury acetate (ISO)

pioglitazone (ISO)

S-nitrosoglutathione (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

tetraphene (ISO)

thimerosal (ISO)

toluene (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytoskeleton organization (ISO,ISS)

insulin secretion (ISO)

maintenance of presynaptic active zone structure (IEA)

modulation of excitatory postsynaptic potential (IMP)

positive regulation of synaptic vesicle recycling (IMP)

presynaptic actin cytoskeleton organization (IEA,ISO)

presynaptic active zone assembly (IBA,IDA,IEA)

protein localization to synapse (IBA,IEA,ISO)

regulation of endosome size (IMP)

regulation of exocytosis (ISO)

regulation of transport (IEA)

regulation of ubiquitin protein ligase activity (IDA)

synapse organization (IDA)

synaptic vesicle clustering (IEA,ISO)

synaptic vesicle targeting (NAS)

Cellular Component

axon (IBA,IDA)

cone cell pedicle (IDA)

cytoskeleton of presynaptic active zone (IBA,IDA,IEA)

dendrite (IDA)

GABA-ergic synapse (IBA)

glutamatergic synapse (IBA,IDA)

Golgi-associated vesicle (IDA,IEA)

growth cone (IDA)

inhibitory synapse (IDA,IEA)

neuromuscular junction (IDA)

neuronal cell body (IDA)

organelle (IEA)

parallel fiber to Purkinje cell synapse (IDA)

perinuclear region of cytoplasm (IDA)

postsynaptic density (IEA,ISO)

presynaptic active zone (IDA,IEA)

presynaptic active zone cytoplasmic component (IDA)

ribbon synapse (IDA,IEA)

rod spherule (IDA)

synapse (IDA,IEA,ISO)

terminal bouton (IDA)

trans-Golgi network (IDA,IEA)

Molecular Function

calcium ion binding (IDA)

calcium-dependent phospholipid binding (IDA,IEA)

metal ion binding (IEA)

profilin binding (IEA,ISO,ISS)

protein binding (IPI,ISO)

structural constituent of presynaptic active zone (IBA,IEA,ISO)

transcription corepressor binding (IEA,IPI)

zinc ion binding (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal cerebellar glomerulus morphology (IMP)

abnormal synaptic vesicle number (IMP)

abnormal synaptic vesicle recycling (IMP)

decreased body length (IMP)

decreased body weight (IMP)

decreased brain weight (IMP)

decreased pons size (IMP)

increased excitatory postsynaptic current amplitude (IMP)

small cerebellum (IMP)

thin cerebellar granule layer (IMP)

thin cerebellar molecular layer (IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	Critical role for Piccolo in synaptic vesicle retrieval.	Ackermann F, etal., Elife. 2019 May 10;8. pii: 46629. doi: 10.7554/eLife.46629.
2.	Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: comparison with Bassoon.	Dick O, etal., J Comp Neurol. 2001 Oct 15;439(2):224-34.
3.	Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartment.	Dresbach T, etal., J Biol Chem. 2006 Mar 3;281(9):6038-47. Epub 2005 Dec 21.
4.	Gene structure and genetic localization of the PCLO gene encoding the presynaptic active zone protein Piccolo.	Fenster SD and Garner CC, Int J Dev Neurosci 2002 Jun-Aug;20(3-5):161-71.
5.	Piccolo, a presynaptic zinc finger protein structurally related to bassoon.	Fenster SD, etal., Neuron 2000 Jan;25(1):203-14.
6.	A conformational switch in the Piccolo C2A domain regulated by alternative splicing.	Garcia J, etal., Nat Struct Mol Biol. 2004 Jan;11(1):45-53. Epub 2003 Dec 29.
7.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8.	An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release.	Gerber SH, etal., EMBO J 2001 Apr 2;20(7):1605-19.
9.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
10.	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	Ivanova D, etal., EMBO J. 2015 Apr 15;34(8):1056-77. doi: 10.15252/embj.201488796. Epub 2015 Feb 4.
11.	Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification.	Juranek J, etal., Eur J Neurosci. 2006 Dec;24(11):3043-52.
12.	The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo.	Kim S, etal., J Biol Chem. 2003 Feb 21;278(8):6291-300. Epub 2002 Dec 6.
13.	Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site.	Limbach C, etal., Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):E392-401. doi: 10.1073/pnas.1101707108. Epub 2011 Jun 28.
14.	Formation of Golgi-derived active zone precursor vesicles.	Maas C, etal., J Neurosci. 2012 Aug 8;32(32):11095-108. doi: 10.1523/JNEUROSCI.0195-12.2012.
15.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
16.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
17.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
19.	Comprehensive gene review and curation	RGD comprehensive gene curation
20.	Immunogold labeling of synaptic vesicle proteins in developing hippocampal neurons.	Tao-Cheng JH, Mol Brain. 2020 Jan 20;13(1):9. doi: 10.1186/s13041-020-0549-x.
21.	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	Waites CL, etal., EMBO J. 2013 Apr 3;32(7):954-69. doi: 10.1038/emboj.2013.27. Epub 2013 Feb 12.
22.	Assembling the presynaptic active zone: a characterization of an active one precursor vesicle.	Zhai RG, etal., Neuron. 2001 Jan;29(1):131-43.

Additional References at PubMed

PMID:10508862	PMID:12401793	PMID:17114649	PMID:18519737	PMID:18570454	PMID:19812333	PMID:20127803	PMID:20332206	PMID:21144999	PMID:21700703	PMID:23936420	PMID:25897839
PMID:26793095	PMID:27907191	PMID:29194628	PMID:29476059	PMID:30053369	PMID:32122952

Genomics

Comparative Map Data

Pclo
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	20,646,604 - 21,005,111 (-)	Ensembl				GRCr8
mRatBN7.2	4	19,691,439 - 20,050,015 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	19,695,315 - 20,049,885 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	24,865,942 - 25,222,133 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	20,697,245 - 21,053,987 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	19,078,298 - 19,437,003 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	16,454,904 - 17,058,921 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	16,454,904 - 17,058,921 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	16,428,814 - 16,661,584 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	4	16,923,700 - 17,031,648 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	15,911,051 - 16,269,090 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	15,219,539 - 15,569,109 (-)	NCBI		Celera
RGSC_v3.1	4	15,911,050 - 16,269,090 (-)	NCBI
Cytogenetic Map	4	q12	NCBI

PCLO
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	82,754,012 - 83,162,884 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	82,754,012 - 83,162,930 (-)	Ensembl			hg38	GRCh38
GRCh37	7	82,383,328 - 82,792,200 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	82,225,378 - 82,630,133 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	82,188,346 - 82,224,200	NCBI
Celera	7	77,083,829 - 77,492,761 (-)	NCBI		Celera
Cytogenetic Map	7	q21.11	NCBI
HuRef	7	76,984,730 - 77,393,999 (-)	NCBI		HuRef
CHM1_1	7	82,313,403 - 82,722,210 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	84,005,231 - 84,414,103 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	81,715,437 - 82,124,409 (-)	NCBI

Pclo
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	14,564,924 - 14,913,479 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	14,564,932 - 14,913,473 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	14,514,906 - 14,863,465 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	14,514,918 - 14,863,459 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	14,514,918 - 14,863,459 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	14,520,924 - 14,801,999 (+)	NCBI		MGSCv36	mm8
Celera	12	24,890,712 - 25,239,859 (+)	NCBI		Celera
Cytogenetic Map	5	A1- A2	NCBI
cM Map	5	6.27	NCBI

Pclo
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	3,152,202 - 3,292,920 (+)	Ensembl
ChiLan1.0	NW_004955410	2,998,345 - 3,334,056 (+)	NCBI	ChiLan1.0	ChiLan1.0

PCLO
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	100,601,124 - 101,013,577 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	148,865,761 - 149,278,209 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	74,714,364 - 75,126,518 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	88,378,218 - 88,789,302 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

PCLO
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	22,385,102 - 22,701,944 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	22,385,100 - 22,706,793 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	21,995,716 - 22,385,731 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	22,770,098 - 23,160,278 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	22,770,852 - 22,983,764 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	22,405,472 - 22,795,049 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	21,940,459 - 22,330,520 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	22,596,545 - 22,986,291 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pclo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	64,071,317 - 64,473,183 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936734	1,277,591 - 1,479,521 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936734	1,273,055 - 1,674,913 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PCLO
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	97,114,511 - 97,513,072 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	97,114,503 - 97,513,081 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	107,331,780 - 107,730,093 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PCLO
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	65,729,762 - 66,129,806 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666042	37,825,087 - 38,233,533 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pclo
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624739	31,143,872 - 31,448,524 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Pclo
1781 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	656
Count of miRNA genes:	183
Interacting mature miRNAs:	223
Transcripts:	ENSRNOT00000007608, ENSRNOT00000008637
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2302371	Stl22	Serum triglyceride level QTL 22	5.15		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	13080146	58080146	Rat
2303585	Bw86	Body weight QTL 86	4		body mass (VT:0001259)	body weight (CMO:0000012)	4	15644309	60644309	Rat
8552903	Pigfal2	Plasma insulin-like growth factor 1 level QTL 2	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	4	1	32668025	Rat
724557	Plsm1	Polydactyly-luxate syndrome (PLS) morphotypes QTL 1		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	4	1	28392287	Rat
9590100	Sffal4	Serum free fatty acids level QTL 4	7.36	0.05	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	4	1	32668025	Rat
8552906	Pigfal3	Plasma insulin-like growth factor 1 level QTL 3			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	4	11038706	56038706	Rat
1357341	Gluco5	Glucose level QTL 5	6.4		adipocyte free fatty acid secretion trait (VT:0010465)	absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)	4	1	34142783	Rat
1357343	Gluco4	Glucose level QTL 4		0.00002	adipocyte glucose uptake trait (VT:0004185)	adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)	4	1	34142783	Rat
8552782	Vie1	Viral induced encephalitis QTL 1	26.4		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	1	35396961	Rat
6478766	Anxrr47	Anxiety related response QTL 47		0.09637	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	11038706	56038706	Rat
631642	Stl2	Serum triglyceride level QTL 2	3.3		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	5894575	57613242	Rat
6478769	Anxrr48	Anxiety related response QTL 48		0.02514	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	11038706	56038706	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	11706604	92690519	Rat
61333	Gluco16	Glucose level QTL 16	4.3	0.00001	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	1	31106810	Rat
2313401	Anxrr27	Anxiety related response QTL 27			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	4	18900697	63900697	Rat
61408	Scl23	Serum cholesterol level QTL 23		0.0005	blood HDL phospholipid amount (VT:0010504)	serum high density lipoprotein phospholipid level (CMO:0001567)	4	1	28392287	Rat
631209	Bw2	Body weight QTL2	4.2		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	1	45429897	Rat
8552803	Bw144	Body weight QTL 144	16		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	1	35396961	Rat
8694374	Bw155	Body weight QTL 155	3.39	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	4	11038706	56038706	Rat
8552801	Bw143	Body weight QTL 143	7.3		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	1	35396961	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5889999	148002343	Rat
9589046	Scfw2	Subcutaneous fat weight QTL 2	5.54	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	4	1	32668025	Rat
8552807	Vie4	Viral induced encephalitis QTL 4	7.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	18900697	63900697	Rat
6478724	Anxrr35	Anxiety related response QTL 35		0.00449	defecation behavior trait (VT:0010462)	defecation measurement (CMO:0000997)	4	11038706	56038706	Rat
61351	Bp33	Blood pressure QTL 33		0.0018	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	1	28392287	Rat
61415	Eae11	Experimental allergic encephalomyelitis QTL 11	2.9		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	4	1	40471598	Rat
1641905	Colcr1	Colorectal carcinoma resistance QTL 1	4.3	0.0003	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	4	8428551	30449094	Rat
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	5889999	50889999	Rat
8552809	Vie5	Viral induced encephalitis QTL 5	25.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	1	35396961	Rat
7387227	Uae40	Urinary albumin excretion QTL 40	2.9	0.0052	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	18913151	63913151	Rat
738021	Hcar13	Hepatocarcinoma resistance QTL 13	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	4	1	33538816	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	1	63900697	Rat
9590304	Scort17	Serum corticosterone level QTL 17	4.96	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	11038706	56038706	Rat
9589097	Slep11	Serum leptin concentration QTL 11	5.09	0.001	blood leptin amount (VT:0005667)	plasma leptin level (CMO:0000781)	4	1	32668025	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
1300141	Bp178	Blood pressure QTL 178			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	10758701	40490708	Rat

Markers in Region

D4Rat150

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	19,944,524 - 19,944,727 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	16,721,186 - 16,721,388	NCBI	Rnor6.0
Rnor_5.0	4	16,697,210 - 16,697,412	UniSTS	Rnor5.0
RGSC_v3.4	4	16,163,196 - 16,163,399	RGD	RGSC3.4
RGSC_v3.4	4	16,163,197 - 16,163,399	UniSTS	RGSC3.4
Celera	4	15,463,961 - 15,464,163	UniSTS
RGSC_v3.1	4	16,163,193 - 16,163,553	RGD
SHRSP x BN Map	4	7.92	UniSTS
SHRSP x BN Map	4	7.92	RGD
Cytogenetic Map	4	q12	UniSTS

RH132306

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	19,753,275 - 19,753,463 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	16,517,622 - 16,517,809	NCBI	Rnor6.0
Rnor_5.0	4	16,491,458 - 16,491,645	UniSTS	Rnor5.0
RGSC_v3.4	4	15,969,717 - 15,969,904	UniSTS	RGSC3.4
Celera	4	15,277,119 - 15,277,306	UniSTS
Cytogenetic Map	4	q12	UniSTS

BE121235

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	19,762,347 - 19,762,524 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	16,526,692 - 16,526,868	NCBI	Rnor6.0
Rnor_5.0	4	16,500,528 - 16,500,704	UniSTS	Rnor5.0
RGSC_v3.4	4	15,978,787 - 15,978,963	UniSTS	RGSC3.4
Celera	4	15,286,190 - 15,286,366	UniSTS
Cytogenetic Map	4	q12	UniSTS

Genetic Models

This gene Pclo is modified in the following models/strains:

WI.SD-Pclo^{Tn(sb-B-Geo)Fkh}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	9	52	157	87	86	55	61	55	6	302	143	11	135	80	91	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001110797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_020098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108294	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286640	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286641	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF138789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF227534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007608 ⟹ ENSRNOP00000007608

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	20,646,604 - 21,005,111 (-)	Ensembl
mRatBN7.2 Ensembl	4	19,754,934 - 20,049,885 (-)	Ensembl
Rnor_6.0 Ensembl	4	16,496,895 - 16,669,368 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000008637 ⟹ ENSRNOP00000008637

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	20,646,604 - 21,005,111 (-)	Ensembl
mRatBN7.2 Ensembl	4	19,695,315 - 20,049,885 (-)	Ensembl
Rnor_6.0 Ensembl	4	16,519,487 - 16,654,811 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093412

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	16,454,904 - 17,058,921 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093578

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	16,519,487 - 17,058,921 (-)	Ensembl

RefSeq Acc Id:

NM_001110797 ⟹ NP_001104267

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,710,304 - 21,005,111 (-)	NCBI
mRatBN7.2	4	19,755,141 - 20,049,955 (-)	NCBI
Rnor_6.0	4	16,519,487 - 17,058,921 (-)	NCBI
Rnor_5.0	4	16,428,814 - 16,661,584 (-)	NCBI
Rnor_5.0	4	16,923,700 - 17,031,648 (-)	NCBI
RGSC_v3.4	4	15,911,051 - 16,269,090 (-)	RGD
Celera	4	15,278,984 - 15,569,109 (-)	NCBI

Sequence:

show sequence

CGCCGGCAAAGCCTGCGGAGGGACTGAGCTCGCGTCTCTTCTCCAGGCAGCAGGGAGGGCGCGG
ACCTACAGGGCTGGGCAGCCTGCACGCCCCCGGGCGGACCCCGGCTGGCGGGGCTCGGACGGCT
ACGGGCTTCTGCACCGGGACGTGTCCCGCCGAGCCATGGGCAACGAGGCGAGCTTGGAAGGGGA
AGGGCTCCCCGAAGGGCTGGCGGCGGCCGCAGGGGCTGGCGGTTCGGGGAGCGCCCTGCACCCC
GGGATCCCAGCCGGCATGGAGGCGGACCTGAGCCAGCTGAGCGAGGAGGAGAGGAGACAGATCG
CTGCTGTCATGTCAAGGGCGCAGGGGCTGCCCAAGGGAAGCGTCCCCCCGGCCGCTGCGGAGTC
GCCCTCCATGCACAGGAAACAAGAGTTGGATAGTAGTCAGGCTCCACAACAACCAGGAAAGCCA
CCGGACCCTGGGCGTCCCACTCAGCCTGGTCTCAGTAAAAGCAGAACTACGGACACGTTTAGGT
CAGAGCAGAAGCTGCCTGGAAGGAGTCCGTCCACGATCAGCTTGAAAGAATCGAAGTCCAGAAC
TGATTTTAAGGAAGAATACAAGTCTAGTATGATGCCTGGTTTCTTCTCAGATGTTAACCCGTTA
AGTGCTGTCTCCTCTGTTGTAAATAAATTCAACCCTTTTGATTTGATATCAGACTCTGAGGCAT
CCCAGGAGGAAACTACAAAGAAACAAAAAGTTGTCCAGAAGGAGCAAGGGAAATCGGAAGGAAT
GGCAAAACCTCCCTTACAGCAACCATCACCTAAGCCGATCCCTAAACAGCAAGGACAAGTGAAG
GAAGTGATCCAGCAAGACAGCTCTCCCAAGTCAGTATCTTCCCAGCAAGCAGAAAAAGTAAAAC
CACAAGCCCCTGGCACAGGAAAGCCTTCCCAACAGAGTCCAGCCCAAACACCAGCTCAGCAAGC
TAGTCCTGGAAAACCTGTAGCCCAACAGCCTGGATCTGCAAAGGCCACAGTCCAGCAGCCAGGG
CCAGCAAAGTCCCCAGCTCAACCAGCAGGGACAGGGAAATCCCCAGCCCAACCTCCAGCCAAGA
CCCCAGGTCAGCAGGCTGGATTAGAGAAGACCTCATCATCGCAGCAGCCTGGGCCAAAGTCTCT
AGCCCAGACTCCTGGTCATGGGAAGTTTCCACTGGGGCCAGTAAAGTCTCCAGCCCAGCAGCCA
GGGACAGCAAAACACCCAGCTCAACAGCCTGGCCCACAGACTGCAGCTAAGGTACCTGGGCCTA
CAAAAACTCCAGCTCAGCAATCTGGACCTGGAAAGACACCAGCTCAACAGCCAGGTCCAACAAA
GCCTTCACCTCAGCAACCCATTCCAGCAAAGCCCCAGCCTCAGCAACCTGTTGCCACAAAAACT
CAGCCTCAACAGTCTGCCCCAGCAAAACCCCAGCCTCAGCAGCCAGCCCCAGCAAAGCCCCAGC
CTCAGCAGCCAACTCCAGCAAAGCCTCAGCCTCAACCGCCCACCCCAGCAAAGCCCCAGCCTCA
ACCGCCCACAGCAACAAAGCCCCAGCCTCAACCGCCCACAGCAACAAAGCCCCACCATCAACAG
CCAGGCCTGGCAAAACCTTCAGCTCAGCAACCTACAAAATCGATAAGCCAAACGGTAACTGGAC
GACCTCTGCAACCACCACCAACTTCTGCAGCACAGACTCCAGCACAAGGCCTCTCGAAAACCAT
CTGTCCTCTTTGCAACACCACTGAACTTCTGTTGCATATTCCAGAAAAGGCCAATTTTAACACA
TGCACTGAGTGTCAAAGCACCGTCTGTAGCCTCTGTGGTTTTAACCCCAACCCTCATTTAACTG
AGATCAAAGAGTGGCTCTGTTTAAACTGTCAGATGCAAAGAGCTCTAGGAGGGGACCTGGCAGC
GGCAATCCCATCCTCACCACAGCCAACCCCAAAGGCCGCCACAGCACCTACAGCAACAGCCAGC
AAATCACCTGTACCGTCACAGCAGGCTTCCCCAAAGAAGGAACCTCCATCCAAACAGGACAGTC
CCAAAGCACTGGAGTCGAAAAAACCGCCAGAGCCGAAAAAACCACCAGAGCCGAAAAAGCCACC
AGAGCCGAAAAAGCCACCGCCATTGGTGAAACAGCCAACCCTTCATGGACCTACCCCAGCTACA
GCCCCACAGCTTCCAGTGGCAGAGGCCTTACCTGAGCCAGCCCCTCCCAAGGAGCCTTCTGGAC
CCCTACCTGAACAAGCCAAGGCCCCCGTTGGAGATGTTGAACCAAAGCAGCCCAAGATGACAGA
GACGCGCGCAGACATCCAATCTTCGTCAACGACAAAACCTGATATTCTGAGCTCTCAAGTGCAG
TCACAGGCTCAAGTGAAAACAGCCTCTCCTTTGAAAACAGACTCTGCCAAACCTTCACAGAGTT
TCCCACCAACAGGAGAAAAAACCACCCCACTTGACTCTAAAGCCATGCCCAGGCCTGCATCAGA
CTCAAAAATTATCTCACAACCTGGGCCCGGTTCTGAGAGCAAGGATCCGAAACACATTGATCCG
ATTCAGAAGAAAGATGAACCTAAGAAAGCACAACCCAAGGGGAGCCCTAAACCAGAAACAAAGC
CAGTGCCAAAAGGATCACCGACACCCTCTGGCACACGACCTACCGCTGGCCAAGCTGCACCCCC
ATCTCAGCAGCCCCCGAAGCCTCAGGAGCAGTCAAGACGTTTTAGCTTGAATCTGGGCGGTATC
ACTGATGCCCCCAAATCACAGCCCACGACTCCTCAAGAAACCGTGACGGGGAAACTCTTCGGCT
TTGGAGCATCCATCTTTAGCCAAGCATCAAACTTAATTTCCACAGCAGGTCAGCAAGGACCACA
TCCACAAACTGGGCCAGCCGCCCCATCAAAGCAAGCCCCTACCCCATCACAGAGTCCTGCTGCT
CAGGGACCTGCCAAGTCCACGGGTCAGCTCCCACCGGCACCTGCTAAGGCGACTGCTGTGAAGA
AGGAGGCAAAAGCTGCAGCAGCTGAAAACTTAGAGTCCAAACCTGAGCAAGCGCCAACAGCGAA
GAAGACAGAGAAAGACAAGAAGCCGCCACCTGCGAAGGTCGGCAAACCTCCACCCTCAGAGCCC
GAAAAGGCTGTCCCGGCCCATAAACCAGACAAGACCACCAAACCCAAACCAGCCTGTCCTCTCT
GTAGAACTGAGCTCAACCTAGGGTCTCAGGAGCCTCCCAACTTCAACACCTGCACAGAATGCAA
GAATCAAGTTTGCAATCTCTGTGGATTTAACCCAACGCCCCACCTGACTGAGATTCAAGAGTGG
CTTTGTTTAAACTGCCAGACACAGAGAGCAATTTCAGGACAACTTGGAGATATGGGCAAAATGC
CACCTGCACCCTCAGGACCCAAAGCATCCCCTATGCCTGCTCCTGCAGAACCTTCATCGCAGAA
AACACCCACAGGGACCCAAGTGAAAGGCAAAAAGAAAGAAGCAGAAGGAAAAACGGAAGCTGAA
AAACCGGTTCCAGAAAAAGAAACAGCATCAATTGAGAAAACCCCTCCAATGGTCACCACAGATC
AAAAACTAGAAGAAAGTGAAGGAAAGAAAAGCAAGGTTTCAGCCCTTCCGGAGAAGAAACCATC
TGAAGAAGAAAAGGCAATATCTGCAGATAAAAAGGAAAGGAAGCCACCTGCTGAAGAAAAGCCA
CCGCTTGAAGAAAAGAAGCCAATCCCCGTAGATAAGAAATTACCCCCAGAAGCAAAACCGTTGT
CCTCAGAGGGGGAAGAGAAACATGAAATACTTAAAGCTCACGTACAAATTCCCGAAGAAGAACC
CACAGGCAAAGTGGCTGCAAAGGCAGGTGAAGAGGAGCAGCAGCCAGACTCCAGGCCTGAAGCT
CTGCCAGGCGCCACACCTCTGACATTACCCAAGGCAGGAGAGAAAGAAAGAGCGGTAGCACAGC
CACAGGCAGAAGGCAGTTCAAAGGATGGCCAAGGCGAGCGGAGCAAAGAAAAGACAGAAAAGGA
AGAGGATAAATCAGACACTTCCAGTTCTCAGCAACCCAAGAGCCCACAAGGCCTGAGTGACACA
GGATATTCTTCTGATGGAATATCAGGTTCCCTTGGGGAAATCCCAAGCCTTATACCCAGTGATG
AGAAAGATTTGCTGAAAGGACTCAAAAAAGATTCTTTCTCACAAGAAAGCAGCCCTTCCAGCCC
CTCAGACTTAGCTAAGTTGGAAAGTACAGTACTATCCATTTTGGAAGCTCAGGCAAGTACACTT
GTTGGTGAAAAAGCAGAAAAGAAAACACAGCCCCAGAAGATTTCTCCTGAAAAGCCACAGGACC
AGCAGAAAACTCAAACTGCATCCGAAACACTGGATATTACTATTTCAGAAGAGGAGATCAAAGA
GAGTCAAGAAAAGAAAGTTAGTCCAAAAAAGGATAGCGAGCAAGGTTTTCCTTCCAGAAAGGAG
CACAAAGAGAAGCCTGAGCTGGTTGATGACCTAAGTCCGCGAAGGGCATCCTATGATTCGGTCG
AAGACAGCAGCGAAAGTGAAAACTCCCCTGTTGTCCGTAGGAAGCGGAGAACTAGTATTGGTTC
GTCAAGCAGCGATGAGTATAAGCAGGAAGACAGTCAAGGTTCGGGGGAAGAGGAGGACTTCATT
CGAAAACAGATTATAGAAATGAGTGCTGATGAGGATGCTTCAGGCTCTGAGGATGAAGAGTTCA
TCAGGAGTCAGCTCAAAGAGATCAGTGGCGTTGGTGAGAGCCAGAAGAGGGAGGAAGCAAAGGG
GAAAGGAAAAGGCGTGGCCGGGAAACACCGACGACTGACTCGAAAGAGCAGTACCAGCTTCGAT
GACGATGCAGGGAGGCGTCATTCCTGGCATGACGAGGATGATGAAACTTTTGATGAAAGTCCTG
AACTCAAATTCCGAGAAACTAAAAGCCAGGAGAGTGAAGAACTCGTCGTCGCTGGAGGAGGAGG
GTTGCGGCGATTTAAGACAATAGAACTCAACAGTACAATAGCAGACAAGTACTCTTCAGAATCC
TCTCAGAAAAAGACAATTTTGTATTTCGATGAAGAGCCAGAATTAGAAATGGAAAGTCTGACAG
ACTCACCCGAAGACAGATCTAGGGGAGAGGGATCCTCTAGTCTCCATGCATCCAGCTTCACTCC
TGGCACATCCCCTACGTCAGTATCGTCCCTTGATGAGGACAGTGACAGTAGCCCAAGTCACAAA
AAAGGAGAAAGCAAGCAGCAGCGCAAAGCTCGGCACAGGTCGCATGGCCCTCTGTTACCTACCA
TTGAAGATTCCTCCGAGGAAGAAGAGCTGAGGGAGGAAGAAGAATTACTAAAAGAACAAGAGAA
GCAGCGAGAATTGGAACAGCAACAGAGGAAGAGTTCTAGTAAGAAATCGAAGAAAGACAAAGAT
GAACTTCGAGCCCAGAGAAGGCGAGAAAGACCAAAGACACCGCCCAGTAATCTCTCTCCCATCG
AGGACGCATCCCCCACAGAAGAACTGCGCCAGGCAGCAGAAATGGAGGAGCTACACAGATCCTC
TTGCTCTGAATACTCACCTAGCATAGAATCAGATCCAGAAGGATTCGAAATAAGCCCCGAGAAA
ATAATAGAAGTTCAAAAAGTTTACAAATTGCCCGCAGCTGTGTCTTTATACTCACCAACAGACG
AGCAATCTGTTATGCAGAAAGAAGGTGTTCAGAAGGCATTAAAAAGTGCTGAGGAGATGTATGA
AGAAATGATGCAGAAACCCCACAAGTACAAAGCTTTCCCAGCTGCAAATGAGAGAGATGAAGTG
TTTGAGAAAGAGCCATTGTACGGTGGTATGTTAATAGAGGACTACATTTACGAGTCTTTAGTAG
AGGACACGTACAATGGGTCAGTAGATGGCAGTCTGCTCACCAGGCAAGAGGAGCAAAACGGGTT
TATGCAGCAGAGAGGGAGAGAACAAAAAGTAAGACTGCAGGAACAGATTTACGATGACCCCATG
CAGAAAATCTCAGACCTCCAGAAGGAGTTTTATGAATTAGAAAGCTTACACTCTGTTGTGCCTC
AAGAAGACATTGTTTCAAGCTCTTACATCATTCCAGAAAGCCATGAGATAGTGGATCTGGGTAG
CATGGTGATGTCTACCAGCGAAGAAAAGAAATTGTTAGATGCCGACTCGGCGTATGAAGAACTC
ATGAGGCGGCAGCAGGTGCAGGTAACAGATGGCTCCAGCCCCGTACAGACTACCATTGGGGATG
ACATGGCAGAGTCCACTCTGGACTTCGACAGGGTGCAAGATGCGTCTTTGACATCAAGTATCCT
TTCTGGAGCATCTCTTACAGACTCAACCAGCAGTGCGACTCTCTCTATCCCAGATGTTAAGATA
ACCCAACAATTTTCAGCAGAAGAACTTGAGGATGAATATGTAACTGATTATACAAGAGAAATTC
AAGATATAATTGCCCACGAGTCACTTATATTGACTTACTCTGAGCCTTCCGAAAGTGCGACGTC
TGTCCCGCCTTCTGACACACCTTCTCTCACGTCCTCTATTTCTTCGGTTTGCACCACAGACAGC
TCCTCACCTGTCACTACCCTCGACAGCCTAACAACTGTTTATACAGAGCCAGCAGATGTAATGA
CTAAATTTAAAGACTCTGAGGAAATTTCTTCAACTTATTTTCCAGGCAGCATTATCGACTATCC
AGAAGATATAAGTGTATCTTTAGATCGGACCATCATGCCAGAAAGTCGAACTAATGAGGATCGG
ATTGTGCTTTCTTTCTCCGGTATGGCACCTTCTGTCGTAGAATCTGTAGGAACTAAGCCTGAGA
GGCCACAAGCTGACACTATTTCCACTGACTTACCTATATCTGAAAAGGATTTGATAAAAGGCAA
GAAAGAGACTGGGGATGGGATTATTTTGGAAGTTTTGGATGCTTACAAAGATAAGAGGGAAGAA
TCAGAGGCTGAACTAACGAAAATCAGCTTGCCTGAGCCTGGGTTGGCCCAAGCGCCTTCTTCCG
TAACAGCCCCTCAAATTAAGGAACAACATGTGTCTCCACATTCTGTATCTGGAAAAATTTCTGG
TCAGGAAAAGCCCACATACAGGTTACCATCTGGCAGTCTTCCTGTTTCTACCCATCCATCTAAA
TCTCGTCCGTTTTTCCGAAGTTCTTCTTTGGACATATCAGCCCAGCCACCTCCTCCCCCTCCAC
CACCTCCTCCCTCCCCCTCCACCTCGTCCCCTCCACCCACCCCACCATTGCCACCAGCAACTTC
TCCTAAGCCACCCACTTATCCCAAAAAAAAGTTGGCGGTTGCAGCTACAGTGACTTCAACTACT
ATTGTTACAACCCATGTTGATGCTCTAACTATGGTAGAGGCCGCAGCTGCTCGCAGGAGCAATG
GGCTGCCTGCCACTAAAATGTGTGCTATTGCACCTCCTCCTGTGCCTCCTAAGCCTTCTCAAAT
TCCAACTGGACTTGTATTTACACATAGGCCAGAGGCAATCAAACCTCCAATTGCCCCCAAGCCA
GCAGTTCCTCAGATTCCAGTTACTACACAGAAACCAACAGATACGTGTCCCAAGCCAACAGGTC
TATCTTTAACTTCAACTATGTCCTTAAATTTAGTTACTTCAGCAGACTACAACGTTCCTTCCCC
TACCTCTCCACTTTCCCCACACTCTAACAAATCCTCACCAAGATATTCTAAGTCTCTCATGGAC
ACTTACGTGGTTATTACATTGCCCTCGGAACCTGGGACTCCAACAGATTCTTCTGCTGCCCAAG
CCATTACAAGTTGGCCCTTGGGATCACCCCCAAAAGATCTGGTTTCCCTTGAAACGGTATTTTC
TGTAGTTCCTCCCATGACATCTACAGAAATTCCAAGTGCTTCACAGCCAACCCTATATACATCT
GGAGCTTTGGGGACATTTTCTGTTACCCCTGCTGTAACAGCCTCTTTGTTTCAAACAGTACCAA
CTTCACTTACACAGTTTCTTCCAGCAGAAGCTTCAAAACCCGAAGTCTCTGCGGTGAGTAGTGC
AGTCCCAAGTGTTGCTCCCAGGAGTGTTTCCATACCAATTCCTCCAGAGCCTCTTGCTCTAGAC
AGGCATCAGTATAAGGAAAATGGAAAGTTGCCACTTATTGGAGATGCCATTGATTTGCGTACAA
TACCAAAATCAGAAGTTAAAGTAACTGAAAAATGTATGGATCTTTCTGCTTCTGCAATGGATGT
GAAAAGGCAGACCACAGCGAATGAGGTTTACAGGCGACAAATTAGTGCTGTCCAACCTTCTATC
ATAAACCTCAGTGCAGCTTCCTCCTTAGGAACTCCAGTCACCATGGACTCTAAGACAGTGGCTG
TTGTCACGTGCACAGACACTACAATTTACACAACAGGCACAGAAAGCCAAGTGGGTATAGAACA
TGCAGTAACATCACCACTGCAGCTTACTACATCAAAACATACTGAGTTACCATACAGGAAACCT
AGTAGCCAGGCTTTTCCTACAATCCGAGATGAAGCACCCATCAACTTATCATTAGGTCCTTCAG
CTCAGGCAGTGACGCTGGCTGTCACGAAGCCCGTCACTGTACCTCCTGTCGGCGTCACAAATGG
ATGGACTGACAGCACTCTATCTCAGGGGGTCGCTGATGGAGAAGTAGTAGATCTCAGCACATCA
AAATCTCACAGAACTGTCGTGACAATGGATGAATCTACGTCAAACGTGGTGACCAAAATCATAG
AGGATGATGAAAAACCAGTTGATCTGACCGCAGGAAGACGAGCGGTGTGCTGTGATATGGTTTA
CACGTTGCCCTTTGGAAGGAGCTGCACGGCACAGCAGCCTGCAACCACCCTTCCCGAAGACCGT
TTTGGTTACAGGGATGACCACTATCAATATGACAGATCAGGGCCCTATGGTTACAGGGGGATTG
GCGGAATGAAACCTTCCATGTCAGATACCAATTTACCAGAAGCTGGACACTTTTTCTATAAAAG
TAAGAATGCCTTTGATTATTCTGGAGGAACTGGTGCAGCAGTAGACCTGACTTCTGGGAGAGTG
TCTACAGGTGAGGTAATGGATTATTCAAGCAAGACTACAGGTCCATACCCAGAAACACGCCAAG
TCATTTCGGGAGTTGGGATTAGTACCCCACAGTATTCCACTGCAAGACTGACTCCACCTCCTGG
ACCCCAGTATGGTGTGGGAAGTGTTTTGAGGTCATCTAATGGTGTTGTCTATTCTTCAGTAGCA
ACTCCAATCCCCTCCACATTTGCTATCACCACTCAACCGGGCTCTATTTTCAGCACCACGGTCA
GGGATTTATCTGGCATTCCTACCACAGATGCAATGACTTCATTATCAGCCCTGCATCAAAGCCA
GCCAATGCCTCGATCGTATTTCATAACAACAGGTGCGTCAGAAACAGACATCGCAGTAACCGGT
ATTGACATCAATGCCAGTCTGCAAACTATTACCATGGAAACTCTTCCTGCTGAGACAATGGACT
CTGTTCCTACCTTAACCACAGCGTCTGAGGTGTTTTCTGAGGTGGTCGGAGAGGAAAGCACCCT
TCTAATTGTCCCTGATGAAGACAAACAACAACAGCAACTTGACTTGGAGCGAGAGCTCCTGGAA
CTGGAGAAAATTAAGCAACAACGCTTTGCTGAAGAACTGGAGTGGGAACGTCAGGAGATTCAGA
GGTTCCGAGAACAAGAGAAGATCATGGTTCAAAAGAAGCTGGAGGAGCTGCAGTCTATGAAGCA
GCACCTTCTCTATCAACAAGAGGAAGAGCGGCAGGCACAGTTCATGATGAGGCAGGAGACGCTA
GCTCAGCAACAGTTACAGCTTGAGCAGATCCAACAGCTGCAACAACAGCTCCACCAGCAGCTCG
AGGAACAAAAACTTCGCCAGATCTACCAGTATAATTATGACCCCTCTGGGACCTCTTCTCCTCA
AACCACCACTGAACAGGCCATTTTAGAGGGTCAATATGCTGCTACAGAGGGCAGTCAGTTTTGG
GCCACTGAAGATGCCACCACTACGGCGTCTACTGTGGTAGCCATTGAAATCCCACAGAGCCAAG
GATGGTACACCGTTCAGTCTGATGGTGTGACTCAGTACATTGCCCCACCTGGTATCCTGAGCAC
TGTTTCAGAGATACCTCTGACAGATGTTGTTGTGAAAGAGGAGAAGCAACCCAAAAAGAGAAGT
TCTGGAGCTAAAGTTCGGGGGCAGTATGATGAGATGGGGGAAAGCGTGGCAGACGATCCACGAA
ATTTAAAAAAGATAGTGGACAGTGGCGTGCAAACTGACGACGAAGAAACTGCTGATCGGAGTTA
CGCAAGTAGGAGAAGAAGAACTAAAAAAAGCGTGGATACCAGTGTCCAAACTGATGACGAAGAT
CAGGATGAGTGGGACATGCCTTCTAGGTCCAGGAGAAAAGCGCGAACAGGGAAATACGGAGATA
GCACCGCAGAGGGTGACAAGACCAAGCCCCTTTCCAAAGTCTCCAGTGTAGCGGTTCAGACAGT
TGCAGAGATATCTGTGCAAACTGAGCCAGTGGGAACCATAAGAACACCTTCCATACGAGCACGG
GTGGATGCCAAGGTAGAAATAATTAAACACATTTCAGCACCTGAAAAGACTTACAAAGGGGGCA
GTTTAGGATGCCAAACAGAAACAGATTCAGACACACAGAGCCCTCCATATCTGGGTGCCACATC
TCCACCCAAAGACAAGAAACGCCCAACACCTTTAGAAATTGGTTATTCTTCTTCTCACCTTCGG
GCAGACCCCACAGTCCAGCTGGCTCCTTCCCCACCCAAATCTCCAAAAGTCCTTTACTCACCCA
TCTCACCACTTTCCCCAGGCAACGCCTTAGAACCAGCCTTTGTACCTTATGAAAAACCCCTCCC
TGATGACATAAGTCCACAGAAAGTACTCCATCCAGATATGGCTAAAGTTCCCCCGGCAAGCCCT
AAGACAGCCAAGATGATGCAGCGTTCAATGTCTGACCCAAAGCCTCTGAGTCCAACAGCAGACG
AAAGTTCCAGGGCTCCTTTTCAGTATTCCGAGGGCTTCACGACTAAAGGTTCCCAAACCATGAC
AGCCTCTGGTACTCAGAAAAAAGTGAAGAGAACACTTCCAAATCCCCCTCCTGAGGAGGTGTCC
ACGGGAACACAGTCAACTTACAGCACCATGGGCACTGCTTCTAGGAGAAGAATGTGCAGAACCA
ATACCATGGCTCGAGCCAAGATTCTCCAGGACATAGACCGAGAGCTCGACCTCGTGGAAAGGGA
GTCTGCCAAGCTTAGAAAGAAGCAAGCAGAACTTGATGAAGAAGAAAAGGAGATTGATGCCAAG
CTGCGGTATCTGGAAATGGGAATTAACAGGAGAAAAGAAGCGTTATTGAAGGAGAGAGAAAAGA
GAGAGCGTGCCTACCTGCAGGGGGTAGCTGAGGACCGCGATTACATGTCTGACAGTGAGGTCAG
CAGTACCAGACCGAGCCGAGTAGAAAGTCAGCACGGCGTTGAGCGGCCAAGAACAGCTCCTCAA
ACTGAATTCAGTCAGTTCATACCACCACAGACCCAAACAGAAGCTCAACTAGTTCCTCCTACAA
GTCCTTACACACAATACCAGTACTCATCACCGGCCCTTCCCACCCAAGCCCCGACCCCATACAC
ACAGCAATCTCATTTTCAACAGCAGACACTATACCATCAGCAAGTTTCACCTTATCAGACTCAG
CCAACCTTCCAAGCTGTGGCAACAATGTCCTTCACACCCCAGGCTCAACCCACTCCAACTCCAC
AGCCATCCTATCAACTACCGTCACAGATGATGGTGATACAACAGAAGCCTCGACAAACCACATT
GTATTTGGAGCCTAAGATAACTTCTAACTATGAAGTGATTCGCAACCAACCCCTGATGATCGCT
CCGGTTTCTACTGATAATACATACGCTGTTTCCCATCTTGGGAGTAAGTACAATAGTTTAGACT
TGAGAATCGGTTTGGAGGAAAGAAGCAGCATGGCAGGCAGTCCAATATCAAGCATATCTGCAGA
CTCCTTCTATGCAGACATTGACCACCACACTTCAAGGAATTATGTCCTAATAGATGACATTGGA
GACATTACCAAAGGGACAGCAGCACTGAGCACTGTATTTAGTCTTCATGAAAAGGATCTGTCAA
AAACAGATCGTCTCCTTAGAACCACTGAGACACGGAGGTCTCAGGAAGTGACAGACTTCCTAGC
GCCTTTGCAGACTTCCTCCAGATTGCATAGCTATGTGAAAGCAGATGAGGATCCAATGGAGGAT
CCTTATGAGTTAAAGCTTCTGAAACATCAGATTAAGCAAGAATTCCGTAGAGGCACTGAGAGCT
TGGATCACCTTGCTGGTCTCTCACATTATTACCATGCCGATACTAGCTATAGGCACTTTCCCAA
GTCTGAAAAGTATAGCATCAGTAGACTCACCCTTGAGAAGCAAGCTGCCAAACAATTACCTGCA
GCCATACTTTACCAAAAGCAATCAAAGCATAAGAAATCATTAATTGACCCTAAAATGTCAAAGT
TTTCACCTATTCAAGAAAGTAGAGACCTTGAACCTGACTATCCCACTTACATGAGTTCTGGCAC
TTCATCCATTGGTGGCATTTCTTCTAGGGCAAGGCTTCTTCAAGATGATATCACATTTGGCCTC
AGAAAAAATATTACAGATCAACAAAAATTTATGGGCTCATCACTTGGGTCAGGACTGGGCACAC
TAGGAAATACTATCCGGTCAGCTCTACAGGATGAAGCAGATAAACCATACAGTAGTGGCAGCAG
GTCCAGGCCTTCCTCCAGGCCTTCTTCTGTCTATGGCCTTGATTTATCAATTAAGAGGGATTCT
TCTAGCTCATCGCTAAGATTGAAAGCTCAAGAGGCTGAAGCTCTGGATGTCTCCTTTGGCCATT
CTTCATCTTCTGCCAGAACTAAGCCCACCAGCTTACCAATCAGCCAGAGCAGAGGAAGAATACC
AATTGTGGCCCAGAGTTCAGAAGAAGAAAGTCCGCTAAGTCCTGTTGGCCAACCAATGGGAATG
GCCAGGGCTGCGGCTGGACCTTTGCCGCCCATATCTGCAGATACGAGGGATCAGTTTGGATCAA
GCCACTCATTGCCTGAAGTTCAGCAACACATGAGAGAAGAGTCACGGACAAGGGGTTATGACCG
TGACATAGCATTCATCATGGATGACTTCCAACATGCTATGTCAGACAGTGAAGCCTATCACTTG
CGTCGGGAGGAAACGGATTGGTTTGATAAACCCAGGGAGTCTCGGTTGGAAAATGGCCATGGTC
TGGATAGGAAACTGCCAGAAAGACTGGTTCACTCTAGACCCCTCAGTCAACACCAGGAGCAAAT
TCTGCAGATGAATGGAAAGACAATACATTACATCTTTCCTCATGCAAGGGTTAAAATCACCAGA
GACTTCAAGGACCACACTGGTTCAGGTAATGGGCTAGGAATTAGAATTGTTGGTGGTAAAGAAA
TCCCTGGACACAGTGGAGAAATTGGAGCCTATATTGCTAAGATTCTTCCTGGTGAAAGTGCGGA
ACACACGGGGCCCCTTATGGAAGGGATGCAAGTATTGGAGTGGAATGGGGTCCCCTTGACTTCT
AAAACATATGAAGAAGTGCAGAGTATCATTAACCAACAAAGTGGGGAAGCAGAAATATGTGTAA
GACTGGACCTCAATATGTTGTCGGATTCCGAAAATCCCCAGCATCTGGAACTTCATGAACCGCC
AAAAGTTGATAAGGCAAAGTCTCCAGGCGTGGATCCCAAGCAGTTGGCGGCAGAGCTGCAGAAA
GTCTCACTCCAGCAGTCCCCACTGGTCATGTCGTCAGTCGTGGAGAAAGGGTCTCATGCTCACT
CAGGTCCCACATCAGCAGGATCCAGTTCTGTTCCCAGCCCCGGGCAGCCAGGGTCGCCTTCAGT
AAGCAAAAAGAAGCATAGCAGTACCAAGCCTACTGATGGACCAAAGGCTGCCTCTCACCCAATT
ACAGGAGAGATTCAGCTTCAAATCAACTACGATCTTGGAAATCTTATAATACATATCCTTCAAG
CAAGAAACCTAGTCCCCAGAGACAACAATGGCTACTCTGACCCGTTTGTTAAGGTGTACCTACT
TCCAGGGAGAGGTCAAGTCATGGTTGTCCAGAATGCAAGTGCTGAGTACAAGAGAAGGACAAAA
TATGTCCAGAAAAGTCTTAATCCTGAGTGGAATCAAACAGTAATTTATAAAAGTATTTCCATGG
AGCAGCTCATGAAGAAGACCTTGGAGGTGACAGTTTGGGATTATGATAGATTCTCTTCCAACGA
CTTCCTTGGAGAGGTATTGATTGATTTATCTAGCACATCTCATCTGGACAACACTCCTCGGTGG
TATCCTCTGAAAGAACAAACTGAGAGCATTGACCATGGCAAGTCTCACTCCAGTCAAAACAGCC
AGCAGTCCCCAAAGCCCTCTGTGATCAAAAGCAGAAGCCACGGTATCTTCCCTGACCCATCCAA
GGACATGCAGGTTCCCACCATTGAGAAGTCCCACAGTAGTCCTGGGAGCTCAAAATCATCATCT
GAAGGCCATCTCCGATCTCACGGACCATCTCGCAGTCAAAGCAAAACCAGTGTCGCCCAGACCC
ACCTGGAAGATGCAGGGGTGGCCATAGCCGCAGCTGAAGCCGCTGTGCAACAACTCCGCATTCA
ACCAAGTAAAAGACGCAAATAAATTCCTCAGCATGGCAGCT

hide sequence

RefSeq Acc Id:

NM_020098 ⟹ NP_064483

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,111 (-)	NCBI
mRatBN7.2	4	19,691,445 - 20,049,955 (-)	NCBI
Rnor_6.0	4	16,454,904 - 17,058,921 (-)	NCBI
Rnor_5.0	4	16,428,814 - 16,661,584 (-)	NCBI
Rnor_5.0	4	16,923,700 - 17,031,648 (-)	NCBI
RGSC_v3.4	4	15,911,051 - 16,269,090 (-)	RGD
Celera	4	15,219,539 - 15,569,109 (-)	RGD

Sequence:

show sequence

CGCCGGCAAAGCCTGCGGAGGGACTGAGCTCGCGTCTCTTCTCCAGGCAGCAGGGAGGGCGCGG
ACCTACAGGGCTGGGCAGCCTGCACGCCCCCGGGCGGACCCCGGCTGGCGGGGCTCGGACGGCT
ACGGGCTTCTGCACCGGGACGTGTCCCGCCGAGCCATGGGCAACGAGGCGAGCTTGGAAGGGGA
AGGGCTCCCCGAAGGGCTGGCGGCGGCCGCAGGGGCTGGCGGTTCGGGGAGCGCCCTGCACCCC
GGGATCCCAGCCGGCATGGAGGCGGACCTGAGCCAGCTGAGCGAGGAGGAGAGGAGACAGATCG
CTGCTGTCATGTCAAGGGCGCAGGGGCTGCCCAAGGGAAGCGTTCCCCCGGCCGCTGCGGAGTC
GCCCTCCATGCACAGGAAACAAGAGTTGGATAGTAGTCAGGCTCCACAACAACCAGGAAAGCCA
CCGGACCCTGGGCGTCCCACTCAGCCTGGTCTCAGTAAAAGCAGAACTACGGACACGTTTAGGT
CAGAGCAGAAGCTGCCTGGAAGGAGTCCGTCCACGATCAGCTTGAAAGAATCGAAGTCCAGAAC
TGATTTTAAGGAAGAATACAAGTCTAGTATGATGCCTGGTTTCTTCTCAGATGTTAACCCGTTA
AGTGCTGTCTCCTCTGTTGTAAATAAATTCAACCCTTTTGATTTGATATCAGACTCTGAGGCAT
CCCAGGAGGAAACTACAAAGAAACAAAAAGTTGTCCAGAAGGAGCAAGGGAAATCGGAAGGAAT
GGCAAAACCTCCCTTACAGCAACCATCACCTAAGCCGATCCCTAAACAGCAAGGACAAGTGAAG
GAAGTGATCCAGCAAGACAGCTCTCCCAAGTCAGTATCTTCCCAGCAAGCAGAAAAAGTAAAAC
CACAAGCCCCTGGCACAGGAAAGCCTTCCCAACAGAGTCCAGCCCAAACACCAGCTCAGCAAGC
TAGTCCTGGAAAACCTGTAGCCCAACAGCCTGGATCTGCAAAGGCCACAGTCCAGCAGCCAGGG
CCAGCAAAGTCCCCAGCTCAACCAGCAGGGACAGGGAAATCCCCAGCCCAACCTCCAGCCAAGA
CCCCAGGTCAGCAGGCTGGATTAGAGAAGACCTCATCATCGCAGCAGCCTGGGCCAAAGTCTCT
AGCCCAGACTCCTGGTCATGGGAAGTTTCCACTGGGGCCAGTAAAGTCTCCAGCCCAGCAGCCA
GGGACAGCAAAACACCCAGCTCAACAGCCTGGCCCACAGACTGCAGCTAAGGTACCTGGGCCTA
CAAAAACTCCAGCTCAGCAATCTGGACCTGGAAAGACACCAGCTCAACAGCCAGGTCCAACAAA
GCCTTCACCTCAGCAACCCATTCCAGCAAAGCCCCAGCCTCAGCAACCTGTTGCCACAAAAACT
CAGCCTCAACAGTCTGCCCCAGCAAAACCCCAGCCTCAGCAGCCAGCCCCAGCAAAGCCCCAGC
CTCAGCAGCCAACTCCAGCAAAGCCTCAGCCTCAACCGCCCACCCCAGCAAAGCCCCAGCCTCA
ACCGCCCACAGCAACAAAGCCCCAGCCTCAACCGCCCACAGCAACAAAGCCCCACCATCAACAG
CCAGGCCTGGCAAAACCTTCAGCTCAGCAACCTACAAAATCGATAAGCCAAACGGTAACTGGAC
GACCTCTGCAACCACCACCAACTTCTGCAGCACAGACTCCAGCACAAGGCCTCTCGAAAACCAT
CTGTCCTCTTTGCAACACCACTGAACTTCTGTTGCATATTCCAGAAAAGGCCAATTTTAACACA
TGCACTGAGTGTCAAAGCACCGTCTGTAGCCTCTGTGGTTTTAACCCCAACCCTCATTTAACTG
AGATCAAAGAGTGGCTCTGTTTAAACTGTCAGATGCAAAGAGCTCTAGGAGGGGACCTGGCAGC
GGCAATCCCATCCTCACCACAGCCAACCCCAAAGGCCGCCACAGCACCTACAGCAACAGCCAGC
AAATCACCTGTACCGTCACAGCAGGCTTCCCCAAAGAAGGAACCTCCATCCAAACAGGACAGTC
CCAAAGCACTGGAGTCGAAAAAACCGCCAGAGCCGAAAAAACCACCAGAGCCGAAAAAGCCACC
AGAGCCGAAAAAGCCACCGCCATTGGTGAAACAGCCAACCCTTCATGGACCTACCCCAGCTACA
GCCCCACAGCTTCCAGTGGCAGAGGCCTTACCTGAGCCAGCCCCTCCCAAGGAGCCTTCTGGAC
CCCTACCTGAACAAGCCAAGGCCCCCGTTGGAGATGTTGAACCAAAGCAGCCCAAGATGACAGA
GACGCGCGCAGACATCCAATCTTCGTCAACGACAAAACCTGATATTCTGAGCTCTCAAGTGCAG
TCACAGGCTCAAGTGAAAACAGCCTCTCCTTTGAAAACAGACTCTGCCAAACCTTCACAGAGTT
TCCCACCAACAGGAGAAAAAACCACCCCACTTGACTCTAAAGCCATGCCCAGGCCTGCATCAGA
CTCAAAAATTATCTCACAACCTGGGCCCGGTTCTGAGAGCAAGGATCCGAAACACATTGATCCG
ATTCAGAAGAAAGATGAACCTAAGAAAGCACAACCCAAGGGGAGCCCTAAACCAGAAACAAAGC
CAGTGCCAAAAGGATCACCGACACCCTCTGGCACACGACCTACCGCTGGCCAAGCTGCACCCCC
ATCTCAGCAGCCCCCGAAGCCTCAGGAGCAGTCAAGACGTTTTAGCTTGAATCTGGGCGGTATC
ACTGATGCCCCCAAATCACAGCCCACGACTCCTCAAGAAACCGTGACGGGGAAACTCTTCGGCT
TTGGAGCATCCATCTTTAGCCAAGCATCAAACTTAATTTCCACAGCAGGTCAGCAAGGACCACA
TCCACAAACTGGGCCAGCCGCCCCATCAAAGCAAGCCCCTACCCCATCACAGAGTCCTGCTGCT
CAGGGACCTGCCAAGTCCACGGGTCAGCTCCCACCGGCACCTGCTAAGGCGACTGCTGTGAAGA
AGGAGGCAAAAGCTGCAGCAGCTGAAAACTTAGAGTCCAAACCTGAGCAAGCGCCAACAGCGAA
GAAGACAGAGAAAGACAAGAAGCCGCCACCTGCGAAGGTCGGCAAACCTCCACCCTCAGAGCCC
GAAAAGGCTGTCCCGGCCCATAAACCAGACAAGACCACCAAACCCAAACCAGCCTGTCCTCTCT
GTAGAACTGAGCTCAACCTAGGGTCTCAGGAGCCTCCCAACTTCAACACCTGCACAGAATGCAA
GAATCAAGTTTGCAATCTCTGTGGATTTAACCCAACGCCCCACCTGACTGAGATTCAAGAGTGG
CTTTGTTTAAACTGCCAGACACAGAGAGCAATTTCAGGACAACTTGGAGATATGGGCAAAATGC
CACCTGCACCCTCAGGACCCAAAGCATCCCCTATGCCTGCTCCTGCAGAACCTTCATCGCAGAA
AACACCCACAGGGACCCAAGTGAAAGGCAAAAAGAAAGAAGCAGAAGGAAAAACGGAAGCTGAA
AAACCGGTTCCAGAAAAAGAAACAGCATCAATTGAGAAAACCCCTCCAATGGTCACCACAGATC
AAAAACTAGAAGAAAGTGAAGGAAAGAAAAGCAAGGTTTCAGCCCTTCCGGAGAAGAAACCATC
TGAAGAAGAAAAGGCAATATCTGCAGATAAAAAGGAAAGGAAGCCACCTGCTGAAGAAAAGCCA
CCGCTTGAAGAAAAGAAGCCAATCCCCGTAGATAAGAAATTACCCCCAGAAGCAAAACCGTTGT
CCTCAGAGGGGGAAGAGAAACATGAAATACTTAAAGCTCACGTACAAATTCCCGAAGAAGAACC
CACAGGCAAAGTGGCTGCAAAGGCAGGTGAAGAGGAGCAGCAGCCAGACTCCAGGCCTGAAGCT
CTGCCAGGCGCCACACCTCTGACATTACCCAAGGCAGGAGAGAAAGAAAGAGCGGTAGCACAGC
CACAGGCAGAAGGCAGTTCAAAGGATGGCCAAGGCGAGCGGAGCAAAGAAAAGACAGAAAAGGA
AGAGGATAAATCAGACACTTCCAGTTCTCAGCAACCCAAGAGCCCACAAGGCCTGAGTGACACA
GGATATTCTTCTGATGGAATATCAGGTTCCCTTGGGGAAATCCCAAGCCTTATACCCAGTGATG
AGAAAGATTTGCTGAAAGGACTCAAAAAAGATTCTTTCTCACAAGAAAGCAGCCCTTCCAGCCC
CTCAGACTTAGCTAAGTTGGAAAGTACAGTACTATCCATTTTGGAAGCTCAGGCAAGTACACTT
GTTGGTGAAAAAGCAGAAAAGAAAACACAGCCCCAGAAGATTTCTCCTGAAAAGCCACAGGACC
AGCAGAAAACTCAAACTGCATCCGAAACACTGGATATTACTATTTCAGAAGAGGAGATCAAAGA
GAGTCAAGAAAAGAAAGTTAGTCCAAAAAAGGATAGCGAGCAAGGTTTTCCTTCCAGAAAGGAG
CACAAAGAGAAGCCTGAGCTGGTTGATGACCTAAGTCCGCGAAGGGCATCCTATGATTCGGTCG
AAGACAGCAGCGAAAGTGAAAACTCCCCTGTTGTCCGTAGGAAGCGGAGAACTAGTATTGGTTC
GTCAAGCAGCGATGAGTATAAGCAGGAAGACAGTCAAGGTTCGGGGGAAGAGGAGGACTTCATT
CGAAAACAGATTATAGAAATGAGTGCTGATGAGGATGCTTCAGGCTCTGAGGATGAAGAGTTCA
TCAGGAGTCAGCTCAAAGAGATCAGTGGCGTTGGTGAGAGCCAGAAGAGGGAGGAAGCAAAGGG
GAAAGGAAAAGGCGTGGCCGGGAAACACCGACGACTGACTCGAAAGAGCAGTACCAGCTTCGAT
GACGATGCAGGGAGGCGTCATTCCTGGCATGACGAGGATGATGAAACTTTTGATGAAAGTCCTG
AACTCAAATTCCGAGAAACTAAAAGCCAGGAGAGTGAAGAACTCGTCGTCGCTGGAGGAGGAGG
GTTGCGGCGATTTAAGACAATAGAACTCAACAGTACAATAGCAGACAAGTACTCTTCAGAATCC
TCTCAGAAAAAGACAATTTTGTATTTCGATGAAGAGCCAGAATTAGAAATGGAAAGTCTGACAG
ACTCACCCGAAGACAGATCTAGGGGAGAGGGATCCTCTAGTCTCCATGCATCCAGCTTCACTCC
TGGCACATCCCCTACGTCAGTATCGTCCCTTGATGAGGACAGTGACAGTAGCCCAAGTCACAAA
AAAGGAGAAAGCAAGCAGCAGCGCAAAGCTCGGCACAGGTCGCATGGCCCTCTGTTACCTACCA
TTGAAGATTCCTCCGAGGAAGAAGAGCTGAGGGAGGAAGAAGAATTACTAAAAGAACAAGAGAA
GCAGCGAGAATTGGAACAGCAACAGAGGAAGAGTTCTAGTAAGAAATCGAAGAAAGACAAAGAT
GAACTTCGAGCCCAGAGAAGGCGAGAAAGACCAAAGACACCGCCCAGTAATCTCTCTCCCATCG
AGGACGCATCCCCCACAGAAGAACTGCGCCAGGCAGCAGAAATGGAGGAGCTACACAGATCCTC
TTGCTCTGAATACTCACCTAGCATAGAATCAGATCCAGAAGGATTCGAAATAAGCCCCGAGAAA
ATAATAGAAGTTCAAAAAGTTTACAAATTGCCCGCAGCTGTGTCTTTATACTCACCAACAGACG
AGCAATCTGTTATGCAGAAAGAAGGTGTTCAGAAGGCATTAAAAAGTGCTGAGGAGATGTATGA
AGAAATGATGCAGAAACCCCACAAGTACAAAGCTTTCCCAGCTGCAAATGAGAGAGATGAAGTG
TTTGAGAAAGAGCCATTGTACGGTGGTATGTTAATAGAGGACTACATTTACGAGTCTTTAGTAG
AGGACACGTACAATGGGTCAGTAGATGGCAGTCTGCTCACCAGGCAAGAGGAGCAAAACGGGTT
TATGCAGCAGAGAGGGAGAGAACAAAAAGTAAGACTGCAGGAACAGATTTACGATGACCCCATG
CAGAAAATCTCAGACCTCCAGAAGGAGTTTTATGAATTAGAAAGCTTACACTCTGTTGTGCCTC
AAGAAGACATTGTTTCAAGCTCTTACATCATTCCAGAAAGCCATGAGATAGTGGATCTGGGTAG
CATGGTGATGTCTACCAGCGAAGAAAAGAAATTGTTAGATGCCGACTCGGCGTATGAAGAACTC
ATGAGGCGGCAGCAGGTGCAGGTAACAGATGGCTCCAGCCCCGTACAGACTACCATTGGGGATG
ACATGGCAGAGTCCACTCTGGACTTCGACAGGGTGCAAGATGCGTCTTTGACATCAAGTATCCT
TTCTGGAGCATCTCTTACAGACTCAACCAGCAGTGCGACTCTCTCTATCCCAGATGTTAAGATA
ACCCAACAATTTTCAGCAGAAGAACTTGAGGATGAATATGTAACTGATTATACAAGAGAAATTC
AAGATATAATTGCCCACGAGTCACTTATATTGACTTACTCTGAGCCTTCCGAAAGTGCGACGTC
TGTCCCGCCTTCTGACACACCTTCTCTCACGTCCTCTATTTCTTCGGTTTGCACCACAGACAGC
TCCTCACCTGTCACTACCCTCGACAGCCTAACAACTGTTTATACAGAGCCAGCAGATGTAATGA
CTAAATTTAAAGACTCTGAGGAAATTTCTTCAACTTATTTTCCAGGCAGCATTATCGACTATCC
AGAAGATATAAGTGTATCTTTAGATCGGACCATCATGCCAGAAAGTCGAACTAATGAGGATCGG
ATTGTGCTTTCTTTCTCCGGTATGGCACCTTCTGTCGTAGAATCTGTAGGAACTAAGCCTGAGA
GGCCACAAGCTGACACTATTTCCACTGACTTACCTATATCTGAAAAGGATTTGATAAAAGGCAA
GAAAGAGACTGGGGATGGGATTATTTTGGAAGTTTTGGATGCTTACAAAGATAAGAGGGAAGAA
TCAGAGGCTGAACTAACGAAAATCAGCTTGCCTGAGCCTGGGTTGGCCCAAGCGCCTTCTTCCG
TAACAGCCCCTCAAATTAAGGAACAACATGTGTCTCCACATTCTGTATCTGGAAAAATTTCTGG
TCAGGAAAAGCCCACATACAGGTTACCATCTGGCAGTCTTCCTGTTTCTACCCATCCATCTAAA
TCTCGTCCGTTTTTCCGAAGTTCTTCTTTGGACATATCAGCCCAGCCACCTCCTCCCCCTCCAC
CACCTCCTCCCTCCCCCTCCACCTCGTCCCCTCCACCCACCCCACCATTGCCACCAGCAACTTC
TCCTAAGCCACCCACTTATCCCAAAAAAAAGTTGGCGGTTGCAGCTACAGTGACTTCAACTACT
ATTGTTACAACCCATGTTGATGCTCTAACTATGGTAGAGGCCGCAGCTGCTCGCAGGAGCAATG
GGCTGCCTGCCACTAAAATGTGTGCTATTGCACCTCCTCCTGTGCCTCCTAAGCCTTCTCAAAT
TCCAACTGGACTTGTATTTACACATAGGCCAGAGGCAATCAAACCTCCAATTGCCCCCAAGCCA
GCAGTTCCTCAGATTCCAGTTACTACACAGAAACCAACAGATACGTGTCCCAAGCCAACAGGTC
TATCTTTAACTTCAACTATGTCCTTAAATTTAGTTACTTCAGCAGACTACAACGTTCCTTCCCC
TACCTCTCCACTTTCCCCACACTCTAACAAATCCTCACCAAGATATTCTAAGTCTCTCATGGAC
ACTTACGTGGTTATTACATTGCCCTCGGAACCTGGGACTCCAACAGATTCTTCTGCTGCCCAAG
CCATTACAAGTTGGCCCTTGGGATCACCCCCAAAAGATCTGGTTTCCCTTGAAACGGTATTTTC
TGTAGTTCCTCCCATGACATCTACAGAAATTCCAAGTGCTTCACAGCCAACCCTATATACATCT
GGAGCTTTGGGGACATTTTCTGTTACCCCTGCTGTAACAGCCTCTTTGTTTCAAACAGTACCAA
CTTCACTTACACAGTTTCTTCCAGCAGAAGCTTCAAAACCCGAAGTCTCTGCGGTGAGTAGTGC
AGTCCCAAGTGTTGCTCCCAGGAGTGTTTCCATACCAATTCCTCCAGAGCCTCTTGCTCTAGAC
AGGCATCAGTATAAGGAAAATGGAAAGTTGCCACTTATTGGAGATGCCATTGATTTGCGTACAA
TACCAAAATCAGAAGTTAAAGTAACTGAAAAATGTATGGATCTTTCTGCTTCTGCAATGGATGT
GAAAAGGCAGACCACAGCGAATGAGGTTTACAGGCGACAAATTAGTGCTGTCCAACCTTCTATC
ATAAACCTCAGTGCAGCTTCCTCCTTAGGAACTCCAGTCACCATGGACTCTAAGACAGTGGCTG
TTGTCACGTGCACAGACACTACAATTTACACAACAGGCACAGAAAGCCAAGTGGGTATAGAACA
TGCAGTAACATCACCACTGCAGCTTACTACATCAAAACATACTGAGTTACCATACAGGAAACCT
AGTAGCCAGGCTTTTCCTACAATCCGAGATGAAGCACCCATCAACTTATCATTAGGTCCTTCAG
CTCAGGCAGTGACGCTGGCTGTCACGAAGCCCGTCACTGTACCTCCTGTCGGCGTCACAAATGG
ATGGACTGACAGCACTCTATCTCAGGGGGTCGCTGATGGAGAAGTAGTAGATCTCAGCACATCA
AAATCTCACAGAACTGTCGTGACAATGGATGAATCTACGTCAAACGTGGTGACCAAAATCATAG
AGGATGATGAAAAACCAGTTGATCTGACCGCAGGAAGACGAGCGGTGTGCTGTGATATGGTTTA
CACGTTGCCCTTTGGAAGGAGCTGCACGGCACAGCAGCCTGCAACCACCCTTCCCGAAGACCGT
TTTGGTTACAGGGATGACCACTATCAATATGACAGATCAGGGCCCTATGGTTACAGGGGGATTG
GCGGAATGAAACCTTCCATGTCAGATACCAATTTACCAGAAGCTGGACACTTTTTCTATAAAAG
TAAGAATGCCTTTGATTATTCTGGAGGAACTGGTGCAGCAGTAGACCTGACTTCTGGGAGAGTG
TCTACAGGTGAGGTAATGGATTATTCAAGCAAGACTACAGGTCCATACCCAGAAACACGCCAAG
TCATTTCGGGAGTTGGGATTAGTACCCCACAGTATTCCACTGCAAGACTGACTCCACCTCCTGG
ACCCCAGTATGGTGTGGGAAGTGTTTTGAGGTCATCTAATGGTGTTGTCTATTCTTCAGTAGCA
ACTCCAATCCCCTCCACATTTGCTATCACCACTCAACCGGGCTCTATTTTCAGCACCACGGTCA
GGGATTTATCTGGCATTCCTACCACAGATGCAATGACTTCATTATCAGCCCTGCATCAAAGCCA
GCCAATGCCTCGATCGTATTTCATAACAACAGGTGCGTCAGAAACAGACATCGCAGTAACCGGT
ATTGACATCAATGCCAGTCTGCAAACTATTACCATGGAAACTCTTCCTGCTGAGACAATGGACT
CTGTTCCTACCTTAACCACAGCGTCTGAGGTGTTTTCTGAGGTGGTCGGAGAGGAAAGCACCCT
TCTAATTGTCCCTGATGAAGACAAACAACAACAGCAACTTGACTTGGAGCGAGAGCTCCTGGAA
CTGGAGAAAATTAAGCAACAACGCTTTGCTGAAGAACTGGAGTGGGAACGTCAGGAGATTCAGA
GGTTCCGAGAACAAGAGAAGATCATGGTTCAAAAGAAGCTGGAGGAGCTGCAGTCTATGAAGCA
GCACCTTCTCTATCAACAAGAGGAAGAGCGGCAGGCACAGTTCATGATGAGGCAGGAGACGCTA
GCTCAGCAACAGTTACAGCTTGAGCAGATCCAACAGCTGCAACAACAGCTCCACCAGCAGCTCG
AGGAACAAAAACTTCGCCAGATCTACCAGTATAATTATGACCCCTCTGGGACCTCTTCTCCTCA
AACCACCACTGAACAGGCCATTTTAGAGGGTCAATATGCTGCTACAGAGGGCAGTCAGTTTTGG
GCCACTGAAGATGCCACCACTACGGCGTCTACTGTGGTAGCCATTGAAATCCCACAGAGCCAAG
GATGGTACACCGTTCAGTCTGATGGTGTGACTCAGTACATTGCCCCACCTGGTATCCTGAGCAC
TGTTTCAGAGATACCTCTGACAGATGTTGTTGTGAAAGAGGAGAAGCAACCCAAAAAGAGAAGT
TCTGGAGCTAAAGTTCGGGGGCAGTATGATGAGATGGGGGAAAGCGTGGCAGACGATCCACGAA
ATTTAAAAAAGATAGTGGACAGTGGCGTGCAAACTGACGACGAAGAAACTGCTGATCGGAGTTA
CGCAAGTAGGAGAAGAAGAACTAAAAAAAGCGTGGATACCAGTGTCCAAACTGATGACGAAGAT
CAGGATGAGTGGGACATGCCTTCTAGGTCCAGGAGAAAAGCGCGAACAGGGAAATACGGAGATA
GCACCGCAGAGGGTGACAAGACCAAGCCCCTTTCCAAAGTCTCCAGTGTAGCGGTTCAGACAGT
TGCAGAGATATCTGTGCAAACTGAGCCAGTGGGAACCATAAGAACACCTTCCATACGAGCACGG
GTGGATGCCAAGGTAGAAATAATTAAACACATTTCAGCACCTGAAAAGACTTACAAAGGGGGCA
GTTTAGGATGCCAAACAGAAACAGATTCAGACACACAGAGCCCTCCATATCTGGGTGCCACATC
TCCACCCAAAGACAAGAAACGCCCAACACCTTTAGAAATTGGTTATTCTTCTTCTCACCTTCGG
GCAGACCCCACAGTCCAGCTGGCTCCTTCCCCACCCAAATCTCCAAAAGTCCTTTACTCACCCA
TCTCACCACTTTCCCCAGGCAACGCCTTAGAACCAGCCTTTGTACCTTATGAAAAACCCCTCCC
TGATGACATAAGTCCACAGAAAGTACTCCATCCAGATATGGCTAAAGTTCCCCCGGCAAGCCCT
AAGACAGCCAAGATGATGCAGCGTTCAATGTCTGACCCAAAGCCTCTGAGTCCAACAGCAGACG
AAAGTTCCAGGGCTCCTTTTCAGTATTCCGAGGGCTTCACGACTAAAGGTTCCCAAACCATGAC
AGCCTCTGGTACTCAGAAAAAAGTGAAGAGAACACTTCCAAATCCCCCTCCTGAGGAGGTGTCC
ACGGGAACACAGTCAACTTACAGCACCATGGGCACTGCTTCTAGGAGAAGAATGTGCAGAACCA
ATACCATGGCTCGAGCCAAGATTCTCCAGGACATAGACCGAGAGCTCGACCTCGTGGAAAGGGA
GTCTGCCAAGCTTAGAAAGAAGCAAGCAGAACTTGATGAAGAAGAAAAGGAGATTGATGCCAAG
CTGCGGTATCTGGAAATGGGAATTAACAGGAGAAAAGAAGCGTTATTGAAGGAGAGAGAAAAGA
GAGAGCGTGCCTACCTGCAGGGGGTAGCTGAGGACCGCGATTACATGTCTGACAGTGAGGTCAG
CAGTACCAGACCGAGCCGAGTAGAAAGTCAGCACGGCGTTGAGCGGCCAAGAACAGCTCCTCAA
ACTGAATTCAGTCAGTTCATACCACCACAGACCCAAACAGAAGCTCAACTAGTTCCTCCTACAA
GTCCTTACACACAATACCAGTACTCATCACCGGCCCTTCCCACCCAAGCCCCGACCCCATACAC
ACAGCAATCTCATTTTCAACAGCAGACACTATACCATCAGCAAGTTTCACCTTATCAGACTCAG
CCAACCTTCCAAGCTGTGGCAACAATGTCCTTCACACCCCAGGCTCAACCCACTCCAACTCCAC
AGCCATCCTATCAACTACCGTCACAGATGATGGTGATACAACAGAAGCCTCGACAAACCACATT
GTATTTGGAGCCTAAGATAACTTCTAACTATGAAGTGATTCGCAACCAACCCCTGATGATCGCT
CCGGTTTCTACTGATAATACATACGCTGTTTCCCATCTTGGGAGTAAGTACAATAGTTTAGACT
TGAGAATCGGTTTGGAGGAAAGAAGCAGCATGGCAGGCAGTCCAATATCAAGCATATCTGCAGA
CTCCTTCTATGCAGACATTGACCACCACACTTCAAGGAATTATGTCCTAATAGATGACATTGGA
GACATTACCAAAGGGACAGCAGCACTGAGCACTGTATTTAGTCTTCATGAAAAGGATCTGTCAA
AAACAGATCGTCTCCTTAGAACCACTGAGACACGGAGGTCTCAGGAAGTGACAGACTTCCTAGC
GCCTTTGCAGACTTCCTCCAGATTGCATAGCTATGTGAAAGCAGATGAGGATCCAATGGAGGAT
CCTTATGAGTTAAAGCTTCTGAAACATCAGATTAAGCAAGAATTCCGTAGAGGCACTGAGAGCT
TGGATCACCTTGCTGGTCTCTCACATTATTACCATGCCGATACTAGCTATAGGCACTTTCCCAA
GTCTGAAAAGTATAGCATCAGTAGACTCACCCTTGAGAAGCAAGCTGCCAAACAATTACCTGCA
GCCATACTTTACCAAAAGCAATCAAAGCATAAGAAATCATTAATTGACCCTAAAATGTCAAAGT
TTTCACCTATTCAAGAAAGTAGAGACCTTGAACCTGACTATCCCACTTACATGAGTTCTGGCAC
TTCATCCATTGGTGGCATTTCTTCTAGGGCAAGGCTTCTTCAAGATGATATCACATTTGGCCTC
AGAAAAAATATTACAGATCAACAAAAATTTATGGGCTCATCACTTGGGTCAGGACTGGGCACAC
TAGGAAATACTATCCGGTCAGCTCTACAGGATGAAGCAGATAAACCATACAGTAGTGGCAGCAG
GTCCAGGCCTTCCTCCAGGCCTTCTTCTGTCTATGGCCTTGATTTATCAATTAAGAGGGATTCT
TCTAGCTCATCGCTAAGATTGAAAGCTCAAGAGGCTGAAGCTCTGGATGTCTCCTTTGGCCATT
CTTCATCTTCTGCCAGAACTAAGCCCACCAGCTTACCAATCAGCCAGAGCAGAGGAAGAATACC
AATTGTGGCCCAGAGTTCAGAAGAAGAAAGTCCGCTAAGTCCTGTTGGCCAACCAATGGGAATG
GCCAGGGCTGCGGCTGGACCTTTGCCGCCCATATCTGCAGATACGAGGGATCAGTTTGGATCAA
GCCACTCATTGCCTGAAGTTCAGCAACACATGAGAGAAGAGTCACGGACAAGGGGTTATGACCG
TGACATAGCATTCATCATGGATGACTTCCAACATGCTATGTCAGACAGTGAAGCCTATCACTTG
CGTCGGGAGGAAACGGATTGGTTTGATAAACCCAGGGAGTCTCGGTTGGAAAATGGCCATGGTC
TGGATAGGAAACTGCCAGAAAGACTGGTTCACTCTAGACCCCTCAGTCAACACCAGGAGCAAAT
TCTGCAGATGAATGGAAAGACAATACATTACATCTTTCCTCATGCAAGGGTTAAAATCACCAGA
GACTTCAAGGACCACACTGGTTCAGGTAATGGGCTAGGAATTAGAATTGTTGGTGGTAAAGAAA
TCCCTGGACACAGTGGAGAAATTGGAGCCTATATTGCTAAGATTCTTCCTGGTGAAAGTGCGGA
ACACACGGGGCCCCTTATGGAAGGGATGCAAGTATTGGAGTGGAATGGGGTCCCCTTGACTTCT
AAAACATATGAAGAAGTGCAGAGTATCATTAACCAACAAAGTGGGGAAGCAGAAATATGTGTAA
GACTGGACCTCAATATGTTGTCGGATTCCGAAAATCCCCAGCATCTGGAACTTCATGAACCGCC
AAAAGTTGATAAGGCAAAGTCTCCAGGCGTGGATCCCAAGCAGTTGGCGGCAGAGCTGCAGAAA
GTCTCACTCCAGCAGTCCCCACTGGTCATGTCGTCAGTCGTGGAGAAAGGGTCTCATGCTCACT
CAGGTCCCACATCAGCAGGATCCAGTTCTGTTCCCAGCCCCGGGCAGCCAGGGTCGCCTTCAGT
AAGCAAAAAGAAGCATAGCAGTACCAAGCCTACTGATGGACCAAAGGCTGCCTCTCACCCAATT
ACAGGAGAGATTCAGCTTCAAATCAACTACGATCTTGGAAATCTTATAATACATATCCTTCAAG
CAAGAAACCTAGTCCCCAGAGACAACAATGGCTACTCTGACCCGTTTGTTAAGGTGTACCTACT
TCCAGGGAGAGGTCAAGTCATGGTTGTCCAGAATGCAAGTGCTGAGTACAAGAGAAGGACAAAA
TATGTCCAGAAAAGTCTTAATCCTGAGTGGAATCAAACAGTAATTTATAAAAGTATTTCCATGG
AGCAGCTCATGAAGAAGACCTTGGAGGTGACAGTTTGGGATTATGATAGATTCTCTTCCAACGA
CTTCCTTGGAGAGGTATTGATTGATTTATCTAGCACATCTCATCTGGACAACACTCCTCGGTGG
TATCCTCTGAAAGAACAAACTGAGAGCATTGACCATGGCAAGTCTCACTCCAGTCAAAACAGCC
AGCAGTCCCCAAAGCCCTCTGTGATCAAAAGCAGAAGCCACGGTATCTTCCCTGACCCATCCAA
GGACATGCAGGTTCCCACCATTGAGAAGTCCCACAGTAGTCCTGGGAGCTCAAAATCATCATCT
GAAGGCCATCTCCGATCTCACGGACCATCTCGCAGTCAAAGCAAAACCAGTGTCGCCCAGACCC
ACCTGGAAGATGCAGGGGTGGCCATAGCCGCAGCTGAAGCCGCTGTGCAACAACTCCGCATTCA
ACCAACAAAGCCCACCAACCACCGGCCTGCAGAGAGCTCCGTGTCAACCGGCTCCTCGGGCAGC
AGCGTTGGCAGTGGGTATAGCGTGGACAGCGAAGGAAGCAGCTGTGTGGCCGGGGAGCCCAATC
TACTTCCCATCCCGAGGATAGGAAAGATGGGACAGAATGGACAGGACCCTGTGAAACAGCCAGG
AATGGGAGCAACAGACACAGAGGGTAAAACTCAAGTAATGGGAGAAATCAAGCTAGCATTGAAG
AAGGAAATGAAAACAGATGGTGAACAGCTAATAGTTGAAATTCTCCAGTGCAGAAATATTACCT
ACAAATTTAAGTCTCCAGATCATTTACCAGATTTATATGTGAAACTATATGTGATAAACATCTC
TACCCAAAAAAAGGTTATTAAAAAGAAGACAAGGGTATGCCGACATGATCGAGAGCCTTCTTTT
AATGAAACTTTTAGATTCAGCCTAAGTCCTGCGGGCCATTCGCTTCAGATTTTACTTTTCTCCA
ATGGAGGGAAGTTTATGAAGAAGACGTTGATTGGAGAAGCATGTATCTGGCTTGACAAAGTGGA
TCTGAGGAAAAGAATAGTCAATTGGCACAAATTGTTGGTGAGTCCCACTCAAACACACTGAGGA
CATTGTCTGCTCAGGGTGAGGAAACAGCTCTGCAGCCTCAGATCGAAACTGGAGTTGAACACTA
CTGTGCTGATCTACATTTTCCAGGGCAAACATGAGATCGCAAGCAAGAAGCAAACAGACAGCCT
TGCTGTGGCACACAAAGAGACTTGAAAAGTTCACGTGTTGAAAGCAAACTGACGAAAACAGGCC
AGAGACACTGGATTGCTCATAGCTGTGAAGAGAAGCTCTGAGAGAAGATTTGACTTTTTAAGAT
AAATATCTTTGATCAGACTGAGTTGGAACTGGAAAAAAAGTGGCACAAAGGTTATTAAGGTGTT
GAAAGGTAGTGTGAAAGCAATCGCTTAAATACACGTAACCTTGTTGAGGAAAAAAAATTGATGT
AATGAATCTTGGTTTTCAAAAGATCAAAATTCCTTGTCTTATATTCTCATGAAACTTCCTGTTT
TGGAATTCTGACATAAGATTCAATTCTGAGTTTTCTACAGGACCAGAAGGTGACTGTGTTTATG
GGGAAAATTAAGCCCGAGTTATGAA

hide sequence

RefSeq Acc Id:

XM_039108289 ⟹ XP_038964217

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI
mRatBN7.2	4	19,691,439 - 20,050,015 (-)	NCBI

RefSeq Acc Id:

XM_039108290 ⟹ XP_038964218

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI
mRatBN7.2	4	19,691,439 - 20,050,015 (-)	NCBI

RefSeq Acc Id:

XM_039108291 ⟹ XP_038964219

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI
mRatBN7.2	4	19,691,439 - 20,050,015 (-)	NCBI

RefSeq Acc Id:

XM_039108294 ⟹ XP_038964222

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI
mRatBN7.2	4	19,691,439 - 20,050,015 (-)	NCBI

RefSeq Acc Id:

XM_039108295 ⟹ XP_038964223

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI
mRatBN7.2	4	19,691,439 - 20,050,015 (-)	NCBI

RefSeq Acc Id:

XM_063286636 ⟹ XP_063142706

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI

RefSeq Acc Id:

XM_063286638 ⟹ XP_063142708

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI

RefSeq Acc Id:

XM_063286639 ⟹ XP_063142709

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,646,604 - 21,005,171 (-)	NCBI

RefSeq Acc Id:

XM_063286640 ⟹ XP_063142710

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,708,352 - 21,005,171 (-)	NCBI

RefSeq Acc Id:

XM_063286641 ⟹ XP_063142711

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,742,861 - 21,005,171 (-)	NCBI

RefSeq Acc Id:

XM_063286642 ⟹ XP_063142712

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	20,742,864 - 21,005,171 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001104267	(Get FASTA)	NCBI Sequence Viewer
	NP_064483	(Get FASTA)	NCBI Sequence Viewer
	XP_038964217	(Get FASTA)	NCBI Sequence Viewer
	XP_038964218	(Get FASTA)	NCBI Sequence Viewer
	XP_038964219	(Get FASTA)	NCBI Sequence Viewer
	XP_038964222	(Get FASTA)	NCBI Sequence Viewer
	XP_038964223	(Get FASTA)	NCBI Sequence Viewer
	XP_063142706	(Get FASTA)	NCBI Sequence Viewer
	XP_063142708	(Get FASTA)	NCBI Sequence Viewer
	XP_063142709	(Get FASTA)	NCBI Sequence Viewer
	XP_063142710	(Get FASTA)	NCBI Sequence Viewer
	XP_063142711	(Get FASTA)	NCBI Sequence Viewer
	XP_063142712	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF07822	(Get FASTA)	NCBI Sequence Viewer
	AAF63196	(Get FASTA)	NCBI Sequence Viewer
	EDL99464	(Get FASTA)	NCBI Sequence Viewer
	EDL99465	(Get FASTA)	NCBI Sequence Viewer
	EDL99466	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007608
	ENSRNOP00000008637
GenBank Protein	Q9JKS6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_064483 ⟸ NM_020098
- Peptide Label:	isoform 1
- UniProtKB:	Q9JLT1 (UniProtKB/Swiss-Prot), Q9JKS6 (UniProtKB/Swiss-Prot), D3Z9C7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNEASLEGEGLPEGLAAAAGAGGSGSALHPGIPAGMEADLSQLSEEERRQIAAVMSRAQGLPK GSVPPAAAESPSMHRKQELDSSQAPQQPGKPPDPGRPTQPGLSKSRTTDTFRSEQKLPGRSPST ISLKESKSRTDFKEEYKSSMMPGFFSDVNPLSAVSSVVNKFNPFDLISDSEASQEETTKKQKVV QKEQGKSEGMAKPPLQQPSPKPIPKQQGQVKEVIQQDSSPKSVSSQQAEKVKPQAPGTGKPSQQ SPAQTPAQQASPGKPVAQQPGSAKATVQQPGPAKSPAQPAGTGKSPAQPPAKTPGQQAGLEKTS SSQQPGPKSLAQTPGHGKFPLGPVKSPAQQPGTAKHPAQQPGPQTAAKVPGPTKTPAQQSGPGK TPAQQPGPTKPSPQQPIPAKPQPQQPVATKTQPQQSAPAKPQPQQPAPAKPQPQQPTPAKPQPQ PPTPAKPQPQPPTATKPQPQPPTATKPHHQQPGLAKPSAQQPTKSISQTVTGRPLQPPPTSAAQ TPAQGLSKTICPLCNTTELLLHIPEKANFNTCTECQSTVCSLCGFNPNPHLTEIKEWLCLNCQM QRALGGDLAAAIPSSPQPTPKAATAPTATASKSPVPSQQASPKKEPPSKQDSPKALESKKPPEP KKPPEPKKPPEPKKPPPLVKQPTLHGPTPATAPQLPVAEALPEPAPPKEPSGPLPEQAKAPVGD VEPKQPKMTETRADIQSSSTTKPDILSSQVQSQAQVKTASPLKTDSAKPSQSFPPTGEKTTPLD SKAMPRPASDSKIISQPGPGSESKDPKHIDPIQKKDEPKKAQPKGSPKPETKPVPKGSPTPSGT RPTAGQAAPPSQQPPKPQEQSRRFSLNLGGITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL ISTAGQQGPHPQTGPAAPSKQAPTPSQSPAAQGPAKSTGQLPPAPAKATAVKKEAKAAAAENLE SKPEQAPTAKKTEKDKKPPPAKVGKPPPSEPEKAVPAHKPDKTTKPKPACPLCRTELNLGSQEP PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDMGKMPPAPSGPKASPM PAPAEPSSQKTPTGTQVKGKKKEAEGKTEAEKPVPEKETASIEKTPPMVTTDQKLEESEGKKSK VSALPEKKPSEEEKAISADKKERKPPAEEKPPLEEKKPIPVDKKLPPEAKPLSSEGEEKHEILK AHVQIPEEEPTGKVAAKAGEEEQQPDSRPEALPGATPLTLPKAGEKERAVAQPQAEGSSKDGQG ERSKEKTEKEEDKSDTSSSQQPKSPQGLSDTGYSSDGISGSLGEIPSLIPSDEKDLLKGLKKDS FSQESSPSSPSDLAKLESTVLSILEAQASTLVGEKAEKKTQPQKISPEKPQDQQKTQTASETLD ITISEEEIKESQEKKVSPKKDSEQGFPSRKEHKEKPELVDDLSPRRASYDSVEDSSESENSPVV RRKRRTSIGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDEEFIRSQLKEISGVG ESQKREEAKGKGKGVAGKHRRLTRKSSTSFDDDAGRRHSWHDEDDETFDESPELKFRETKSQES EELVVAGGGGLRRFKTIELNSTIADKYSSESSQKKTILYFDEEPELEMESLTDSPEDRSRGEGS SSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRSHGPLLPTIEDSSEEEELRE EEELLKEQEKQRELEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQA AEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPAAVSLYSPTDEQSVMQKEGVQK ALKSAEEMYEEMMQKPHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSL LTRQEEQNGFMQQRGREQKVRLQEQIYDDPMQKISDLQKEFYELESLHSVVPQEDIVSSSYIIP ESHEIVDLGSMVMSTSEEKKLLDADSAYEELMRRQQVQVTDGSSPVQTTIGDDMAESTLDFDRV QDASLTSSILSGASLTDSTSSATLSIPDVKITQQFSAEELEDEYVTDYTREIQDIIAHESLILT YSEPSESATSVPPSDTPSLTSSISSVCTTDSSSPVTTLDSLTTVYTEPADVMTKFKDSEEISST YFPGSIIDYPEDISVSLDRTIMPESRTNEDRIVLSFSGMAPSVVESVGTKPERPQADTISTDLP ISEKDLIKGKKETGDGIILEVLDAYKDKREESEAELTKISLPEPGLAQAPSSVTAPQIKEQHVS PHSVSGKISGQEKPTYRLPSGSLPVSTHPSKSRPFFRSSSLDISAQPPPPPPPPPPSPSTSSPP PTPPLPPATSPKPPTYPKKKLAVAATVTSTTIVTTHVDALTMVEAAAARRSNGLPATKMCAIAP PPVPPKPSQIPTGLVFTHRPEAIKPPIAPKPAVPQIPVTTQKPTDTCPKPTGLSLTSTMSLNLV TSADYNVPSPTSPLSPHSNKSSPRYSKSLMDTYVVITLPSEPGTPTDSSAAQAITSWPLGSPPK DLVSLETVFSVVPPMTSTEIPSASQPTLYTSGALGTFSVTPAVTASLFQTVPTSLTQFLPAEAS KPEVSAVSSAVPSVAPRSVSIPIPPEPLALDRHQYKENGKLPLIGDAIDLRTIPKSEVKVTEKC MDLSASAMDVKRQTTANEVYRRQISAVQPSIINLSAASSLGTPVTMDSKTVAVVTCTDTTIYTT GTESQVGIEHAVTSPLQLTTSKHTELPYRKPSSQAFPTIRDEAPINLSLGPSAQAVTLAVTKPV TVPPVGVTNGWTDSTLSQGVADGEVVDLSTSKSHRTVVTMDESTSNVVTKIIEDDEKPVDLTAG RRAVCCDMVYTLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNL PEAGHFFYKSKNAFDYSGGTGAAVDLTSGRVSTGEVMDYSSKTTGPYPETRQVISGVGISTPQY STARLTPPPGPQYGVGSVLRSSNGVVYSSVATPIPSTFAITTQPGSIFSTTVRDLSGIPTTDAM TSLSALHQSQPMPRSYFITTGASETDIAVTGIDINASLQTITMETLPAETMDSVPTLTTASEVF SEVVGEESTLLIVPDEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQK KLEELQSMKQHLLYQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKLRQIYQYN YDPSGTSSPQTTTEQAILEGQYAATEGSQFWATEDATTTASTVVAIEIPQSQGWYTVQSDGVTQ YIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYDEMGESVADDPRNLKKIVDSGVQT DDEETADRSYASRRRRTKKSVDTSVQTDDEDQDEWDMPSRSRRKARTGKYGDSTAEGDKTKPLS KVSSVAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTETDSDT QSPPYLGATSPPKDKKRPTPLEIGYSSSHLRADPTVQLAPSPPKSPKVLYSPISPLSPGNALEP AFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYSEG FTTKGSQTMTASGTQKKVKRTLPNPPPEEVSTGTQSTYSTMGTASRRRMCRTNTMARAKILQDI DRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAED RDYMSDSEVSSTRPSRVESQHGVERPRTAPQTEFSQFIPPQTQTEAQLVPPTSPYTQYQYSSPA LPTQAPTPYTQQSHFQQQTLYHQQVSPYQTQPTFQAVATMSFTPQAQPTPTPQPSYQLPSQMMV IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTYAVSHLGSKYNSLDLRIGLEERSSMA GSPISSISADSFYADIDHHTSRNYVLIDDIGDITKGTAALSTVFSLHEKDLSKTDRLLRTTETR RSQEVTDFLAPLQTSSRLHSYVKADEDPMEDPYELKLLKHQIKQEFRRGTESLDHLAGLSHYYH ADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQESRDLEP DYPTYMSSGTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGSGLGTLGNTIRSALQDE ADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFGHSSSSARTKPTSL PISQSRGRIPIVAQSSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMR EESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESRLENGHGLDRKLPERLVHS RPLSQHQEQILQMNGKTIHYIFPHARVKITRDFKDHTGSGNGLGIRIVGGKEIPGHSGEIGAYI AKILPGESAEHTGPLMEGMQVLEWNGVPLTSKTYEEVQSIINQQSGEAEICVRLDLNMLSDSEN PQHLELHEPPKVDKAKSPGVDPKQLAAELQKVSLQQSPLVMSSVVEKGSHAHSGPTSAGSSSVP SPGQPGSPSVSKKKHSSTKPTDGPKAASHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGY SDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTV WDYDRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQNSQQSPKPSVIKSR SHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVAQTHLEDAGVAIAAA EAAVQQLRIQPTKPTNHRPAESSVSTGSSGSSVGSGYSVDSEGSSCVAGEPNLLPIPRIGKMGQ NGQDPVKQPGMGATDTEGKTQVMGEIKLALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDL YVKLYVINISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMKKTLIG EACIWLDKVDLRKRIVNWHKLLVSPTQTH hide sequence

RefSeq Acc Id:	NP_001104267 ⟸ NM_001110797
- Peptide Label:	isoform 2
- UniProtKB:	F1M7V4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNEASLEGEGLPEGLAAAAGAGGSGSALHPGIPAGMEADLSQLSEEERRQIAAVMSRAQGLPK GSVPPAAAESPSMHRKQELDSSQAPQQPGKPPDPGRPTQPGLSKSRTTDTFRSEQKLPGRSPST ISLKESKSRTDFKEEYKSSMMPGFFSDVNPLSAVSSVVNKFNPFDLISDSEASQEETTKKQKVV QKEQGKSEGMAKPPLQQPSPKPIPKQQGQVKEVIQQDSSPKSVSSQQAEKVKPQAPGTGKPSQQ SPAQTPAQQASPGKPVAQQPGSAKATVQQPGPAKSPAQPAGTGKSPAQPPAKTPGQQAGLEKTS SSQQPGPKSLAQTPGHGKFPLGPVKSPAQQPGTAKHPAQQPGPQTAAKVPGPTKTPAQQSGPGK TPAQQPGPTKPSPQQPIPAKPQPQQPVATKTQPQQSAPAKPQPQQPAPAKPQPQQPTPAKPQPQ PPTPAKPQPQPPTATKPQPQPPTATKPHHQQPGLAKPSAQQPTKSISQTVTGRPLQPPPTSAAQ TPAQGLSKTICPLCNTTELLLHIPEKANFNTCTECQSTVCSLCGFNPNPHLTEIKEWLCLNCQM QRALGGDLAAAIPSSPQPTPKAATAPTATASKSPVPSQQASPKKEPPSKQDSPKALESKKPPEP KKPPEPKKPPEPKKPPPLVKQPTLHGPTPATAPQLPVAEALPEPAPPKEPSGPLPEQAKAPVGD VEPKQPKMTETRADIQSSSTTKPDILSSQVQSQAQVKTASPLKTDSAKPSQSFPPTGEKTTPLD SKAMPRPASDSKIISQPGPGSESKDPKHIDPIQKKDEPKKAQPKGSPKPETKPVPKGSPTPSGT RPTAGQAAPPSQQPPKPQEQSRRFSLNLGGITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL ISTAGQQGPHPQTGPAAPSKQAPTPSQSPAAQGPAKSTGQLPPAPAKATAVKKEAKAAAAENLE SKPEQAPTAKKTEKDKKPPPAKVGKPPPSEPEKAVPAHKPDKTTKPKPACPLCRTELNLGSQEP PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDMGKMPPAPSGPKASPM PAPAEPSSQKTPTGTQVKGKKKEAEGKTEAEKPVPEKETASIEKTPPMVTTDQKLEESEGKKSK VSALPEKKPSEEEKAISADKKERKPPAEEKPPLEEKKPIPVDKKLPPEAKPLSSEGEEKHEILK AHVQIPEEEPTGKVAAKAGEEEQQPDSRPEALPGATPLTLPKAGEKERAVAQPQAEGSSKDGQG ERSKEKTEKEEDKSDTSSSQQPKSPQGLSDTGYSSDGISGSLGEIPSLIPSDEKDLLKGLKKDS FSQESSPSSPSDLAKLESTVLSILEAQASTLVGEKAEKKTQPQKISPEKPQDQQKTQTASETLD ITISEEEIKESQEKKVSPKKDSEQGFPSRKEHKEKPELVDDLSPRRASYDSVEDSSESENSPVV RRKRRTSIGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDEEFIRSQLKEISGVG ESQKREEAKGKGKGVAGKHRRLTRKSSTSFDDDAGRRHSWHDEDDETFDESPELKFRETKSQES EELVVAGGGGLRRFKTIELNSTIADKYSSESSQKKTILYFDEEPELEMESLTDSPEDRSRGEGS SSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRSHGPLLPTIEDSSEEEELRE EEELLKEQEKQRELEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQA AEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPAAVSLYSPTDEQSVMQKEGVQK ALKSAEEMYEEMMQKPHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSL LTRQEEQNGFMQQRGREQKVRLQEQIYDDPMQKISDLQKEFYELESLHSVVPQEDIVSSSYIIP ESHEIVDLGSMVMSTSEEKKLLDADSAYEELMRRQQVQVTDGSSPVQTTIGDDMAESTLDFDRV QDASLTSSILSGASLTDSTSSATLSIPDVKITQQFSAEELEDEYVTDYTREIQDIIAHESLILT YSEPSESATSVPPSDTPSLTSSISSVCTTDSSSPVTTLDSLTTVYTEPADVMTKFKDSEEISST YFPGSIIDYPEDISVSLDRTIMPESRTNEDRIVLSFSGMAPSVVESVGTKPERPQADTISTDLP ISEKDLIKGKKETGDGIILEVLDAYKDKREESEAELTKISLPEPGLAQAPSSVTAPQIKEQHVS PHSVSGKISGQEKPTYRLPSGSLPVSTHPSKSRPFFRSSSLDISAQPPPPPPPPPPSPSTSSPP PTPPLPPATSPKPPTYPKKKLAVAATVTSTTIVTTHVDALTMVEAAAARRSNGLPATKMCAIAP PPVPPKPSQIPTGLVFTHRPEAIKPPIAPKPAVPQIPVTTQKPTDTCPKPTGLSLTSTMSLNLV TSADYNVPSPTSPLSPHSNKSSPRYSKSLMDTYVVITLPSEPGTPTDSSAAQAITSWPLGSPPK DLVSLETVFSVVPPMTSTEIPSASQPTLYTSGALGTFSVTPAVTASLFQTVPTSLTQFLPAEAS KPEVSAVSSAVPSVAPRSVSIPIPPEPLALDRHQYKENGKLPLIGDAIDLRTIPKSEVKVTEKC MDLSASAMDVKRQTTANEVYRRQISAVQPSIINLSAASSLGTPVTMDSKTVAVVTCTDTTIYTT GTESQVGIEHAVTSPLQLTTSKHTELPYRKPSSQAFPTIRDEAPINLSLGPSAQAVTLAVTKPV TVPPVGVTNGWTDSTLSQGVADGEVVDLSTSKSHRTVVTMDESTSNVVTKIIEDDEKPVDLTAG RRAVCCDMVYTLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNL PEAGHFFYKSKNAFDYSGGTGAAVDLTSGRVSTGEVMDYSSKTTGPYPETRQVISGVGISTPQY STARLTPPPGPQYGVGSVLRSSNGVVYSSVATPIPSTFAITTQPGSIFSTTVRDLSGIPTTDAM TSLSALHQSQPMPRSYFITTGASETDIAVTGIDINASLQTITMETLPAETMDSVPTLTTASEVF SEVVGEESTLLIVPDEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQK KLEELQSMKQHLLYQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKLRQIYQYN YDPSGTSSPQTTTEQAILEGQYAATEGSQFWATEDATTTASTVVAIEIPQSQGWYTVQSDGVTQ YIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYDEMGESVADDPRNLKKIVDSGVQT DDEETADRSYASRRRRTKKSVDTSVQTDDEDQDEWDMPSRSRRKARTGKYGDSTAEGDKTKPLS KVSSVAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTETDSDT QSPPYLGATSPPKDKKRPTPLEIGYSSSHLRADPTVQLAPSPPKSPKVLYSPISPLSPGNALEP AFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYSEG FTTKGSQTMTASGTQKKVKRTLPNPPPEEVSTGTQSTYSTMGTASRRRMCRTNTMARAKILQDI DRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAED RDYMSDSEVSSTRPSRVESQHGVERPRTAPQTEFSQFIPPQTQTEAQLVPPTSPYTQYQYSSPA LPTQAPTPYTQQSHFQQQTLYHQQVSPYQTQPTFQAVATMSFTPQAQPTPTPQPSYQLPSQMMV IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTYAVSHLGSKYNSLDLRIGLEERSSMA GSPISSISADSFYADIDHHTSRNYVLIDDIGDITKGTAALSTVFSLHEKDLSKTDRLLRTTETR RSQEVTDFLAPLQTSSRLHSYVKADEDPMEDPYELKLLKHQIKQEFRRGTESLDHLAGLSHYYH ADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQESRDLEP DYPTYMSSGTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGSGLGTLGNTIRSALQDE ADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFGHSSSSARTKPTSL PISQSRGRIPIVAQSSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMR EESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESRLENGHGLDRKLPERLVHS RPLSQHQEQILQMNGKTIHYIFPHARVKITRDFKDHTGSGNGLGIRIVGGKEIPGHSGEIGAYI AKILPGESAEHTGPLMEGMQVLEWNGVPLTSKTYEEVQSIINQQSGEAEICVRLDLNMLSDSEN PQHLELHEPPKVDKAKSPGVDPKQLAAELQKVSLQQSPLVMSSVVEKGSHAHSGPTSAGSSSVP SPGQPGSPSVSKKKHSSTKPTDGPKAASHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGY SDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYVQKSLNPEWNQTVIYKSISMEQLMKKTLEVTV WDYDRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQNSQQSPKPSVIKSR SHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVAQTHLEDAGVAIAAA EAAVQQLRIQPSKRRK hide sequence

Ensembl Acc Id:

ENSRNOP00000008637 ⟸ ENSRNOT00000008637

Ensembl Acc Id:

ENSRNOP00000007608 ⟸ ENSRNOT00000007608

RefSeq Acc Id:	XP_038964223 ⟸ XM_039108295
- Peptide Label:	isoform X8
- UniProtKB:	Q9JLT1 (UniProtKB/Swiss-Prot), Q9JKS6 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038964219 ⟸ XM_039108291
- Peptide Label:	isoform X6
- UniProtKB:	Q9JLT1 (UniProtKB/Swiss-Prot), Q9JKS6 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038964218 ⟸ XM_039108290
- Peptide Label:	isoform X2
- UniProtKB:	Q9JLT1 (UniProtKB/Swiss-Prot), Q9JKS6 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038964222 ⟸ XM_039108294
- Peptide Label:	isoform X7
- UniProtKB:	F1M7V4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038964217 ⟸ XM_039108289
- Peptide Label:	isoform X1
- UniProtKB:	Q9JLT1 (UniProtKB/Swiss-Prot), Q9JKS6 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063142706 ⟸ XM_063286636
- Peptide Label:	isoform X3
- UniProtKB:	Q9JLT1 (UniProtKB/Swiss-Prot), Q9JKS6 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063142709 ⟸ XM_063286639
- Peptide Label:	isoform X5
- UniProtKB:	Q9JLT1 (UniProtKB/Swiss-Prot), Q9JKS6 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063142708 ⟸ XM_063286638
- Peptide Label:	isoform X4
- UniProtKB:	Q9JLT1 (UniProtKB/Swiss-Prot), Q9JKS6 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063142710 ⟸ XM_063286640
- Peptide Label:	isoform X9
- UniProtKB:	F1M7V4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142711 ⟸ XM_063286641
- Peptide Label:	isoform X10
- UniProtKB:	F1M7V4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142712 ⟸ XM_063286642
- Peptide Label:	isoform X10
- UniProtKB:	F1M7V4 (UniProtKB/TrEMBL)

Protein Domains

C2 PDZ

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69406	AgrOrtholog
BioCyc Gene	G2FUF-45890	BioCyc
Ensembl Genes	ENSRNOG00000005726	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000007608	ENTREZGENE
	ENSRNOT00000008637	ENTREZGENE
Gene3D-CATH	2.30.42.10	UniProtKB/Swiss-Prot
	2.60.40.150	UniProtKB/Swiss-Prot
	3.30.40.10	UniProtKB/Swiss-Prot
InterPro	C2_Ca-dep	UniProtKB/Swiss-Prot
	C2_domain_sf	UniProtKB/Swiss-Prot
	PCLO_FYVE1	UniProtKB/Swiss-Prot
	PDZ/DHR/GLGF	UniProtKB/Swiss-Prot
	PDZ_sf	UniProtKB/Swiss-Prot
	Presynaptic_Scaffold_Bsn/Pclo	UniProtKB/Swiss-Prot
	Znf_FYVE_PHD	UniProtKB/Swiss-Prot
	Znf_piccolo	UniProtKB/Swiss-Prot
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot
KEGG Report	rno:56768	UniProtKB/Swiss-Prot
NCBI Gene	56768	ENTREZGENE
PANTHER	PICCOLO/BASSOON	UniProtKB/Swiss-Prot
	PTHR14113:SF6	UniProtKB/Swiss-Prot
Pfam	PDZ	UniProtKB/Swiss-Prot
	PF00168	UniProtKB/Swiss-Prot
	zf-piccolo	UniProtKB/Swiss-Prot
PhenoGen	Pclo	PhenoGen
PROSITE	PDZ	UniProtKB/Swiss-Prot
	PS50004	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000005726	RatGTEx
SMART	PDZ	UniProtKB/Swiss-Prot
	SM00239	UniProtKB/Swiss-Prot
Superfamily-SCOP	FYVE_PHD_ZnF	UniProtKB/Swiss-Prot
	PDZ	UniProtKB/Swiss-Prot
	SSF49562	UniProtKB/Swiss-Prot
UniProt	A6K5F5_RAT	UniProtKB/TrEMBL
	A6K5F6_RAT	UniProtKB/TrEMBL
	A6K5F7_RAT	UniProtKB/TrEMBL
	D3Z9C7	ENTREZGENE, UniProtKB/TrEMBL
	F1M7V4	ENTREZGENE, UniProtKB/TrEMBL
	PCLO_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9JLT1	ENTREZGENE
UniProt Secondary	Q9JLT1	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Pclo	piccolo (presynaptic cytomatrix protein)	LOC108350654	protein piccolo-like	Data merged from RGD:11515100	737654	PROVISIONAL
2016-08-02	LOC108350654	protein piccolo-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-09-10	Pclo	piccolo (presynaptic cytomatrix protein)		presynaptic cytomatrix protein	Name updated	1299863	APPROVED
2002-06-10	Pclo	presynaptic cytomatrix protein			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localizes to the presynaptic cytoskeletal matrix	69383
gene_function	binds Ca2+ by virtue of its C(2)A-domain	68715
gene_process	may function as a Ca2+ sensor in short-term synaptic plasticity when high Ca2+ concentrations accumulate during repetitive stimulation	68715
gene_process	may function as a Ca2+ sensor in short-term synaptic plasticity when high Ca2+ concentrations accumulate during repetitive stimulation	69383
gene_process	involved in the assembly and function of presynaptic active zones as sites of neurotransmitter release	1299209

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Mammalian Phenotype

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Mammalian Phenotype