Pdcd6ip (programmed cell death 6 interacting protein) - Rat Genome Database

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Gene: Pdcd6ip (programmed cell death 6 interacting protein) Rattus norvegicus
Analyze
Symbol: Pdcd6ip
Name: programmed cell death 6 interacting protein
RGD ID: 68357
Description: Enables SH3 domain binding activity. Predicted to be involved in several processes, including bicellular tight junction assembly; cytokinetic process; and positive regulation of cellular component biogenesis. Located in neuronal cell body and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 29. Orthologous to human PDCD6IP (programmed cell death 6 interacting protein); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AIP1; ALG-2 interacting protein 1; ALG-2 interacting protein X; ALG-2-interacting protein 1; Alix; programmed cell death 6-interacting protein; RGD1561176
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88122,469,223 - 122,524,993 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8122,469,223 - 122,524,993 (-)EnsemblGRCr8
mRatBN7.28113,590,998 - 113,646,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8113,590,998 - 113,646,773 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8119,207,150 - 119,262,921 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08117,406,414 - 117,462,188 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08115,249,172 - 115,304,948 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd8123,356,969 - 123,412,738 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive8125,462,988 - 125,518,649 (-)NCBILyon_Normotensive
Lyon_Hypertensive8123,945,791 - 124,001,557 (-)NCBILyon_Hypertensive
F344_StmMcwi8115,353,999 - 115,409,775 (-)NCBIF344_StmMcwi
Rnor_6.08121,916,233 - 121,973,145 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8121,916,185 - 121,973,125 (-)Ensemblrn6Rnor6.0
Rnor_5.08121,231,793 - 121,287,105 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48118,314,910 - 118,350,134 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8112,840,809 - 112,895,775 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1,4-dithiothreitol  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenthion  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furfural  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hesperetin  (ISO)
Honokiol  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-1,4-dithiothreitol  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
morusin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nitric oxide  (ISO)
oxybenzone  (EXP)
ozone  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
poly(I:C)  (EXP)
pyrene  (EXP)
rac-lactic acid  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
uranium atom  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes. Chen B, etal., J Biol Chem 2000 Jun 23;275(25):19275-81.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Early increase of apoptosis-linked gene-2 interacting protein X in areas of kainate-induced neurodegeneration. Hemming FJ, etal., Neuroscience. 2004;123(4):887-95.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:8889548   PMID:9880530   PMID:10200558   PMID:12771190   PMID:14505570   PMID:14519844   PMID:15086793   PMID:15326289   PMID:15557335   PMID:16501490   PMID:16957052   PMID:17634366  
PMID:18641129   PMID:19056867   PMID:19199708   PMID:19520058   PMID:19523902   PMID:19706535   PMID:19946888   PMID:20616062   PMID:21276792   PMID:21423176   PMID:22547407   PMID:22660413  
PMID:22871113   PMID:23092844   PMID:23376485   PMID:23523921   PMID:23533145   PMID:23924735   PMID:24105262   PMID:24107264   PMID:24769233   PMID:27336173   PMID:31077357  


Genomics

Comparative Map Data
Pdcd6ip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88122,469,223 - 122,524,993 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8122,469,223 - 122,524,993 (-)EnsemblGRCr8
mRatBN7.28113,590,998 - 113,646,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8113,590,998 - 113,646,773 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8119,207,150 - 119,262,921 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08117,406,414 - 117,462,188 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08115,249,172 - 115,304,948 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd8123,356,969 - 123,412,738 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive8125,462,988 - 125,518,649 (-)NCBILyon_Normotensive
Lyon_Hypertensive8123,945,791 - 124,001,557 (-)NCBILyon_Hypertensive
F344_StmMcwi8115,353,999 - 115,409,775 (-)NCBIF344_StmMcwi
Rnor_6.08121,916,233 - 121,973,145 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8121,916,185 - 121,973,125 (-)Ensemblrn6Rnor6.0
Rnor_5.08121,231,793 - 121,287,105 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48118,314,910 - 118,350,134 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8112,840,809 - 112,895,775 (-)NCBICelera
Cytogenetic Map8q32NCBI
PDCD6IP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38333,798,630 - 33,869,703 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl333,798,571 - 33,869,707 (+)Ensemblhg38GRCh38
GRCh37333,840,122 - 33,911,195 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36333,814,561 - 33,886,198 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34333,814,560 - 33,886,198NCBI
Celera333,783,127 - 33,854,073 (+)NCBICelera
Cytogenetic Map3p22.3NCBI
HuRef333,781,264 - 33,852,387 (+)NCBIHuRef
CHM1_1333,789,988 - 33,861,201 (+)NCBICHM1_1
T2T-CHM13v2.0333,799,362 - 33,870,437 (+)NCBIT2T-CHM13v2.0
Pdcd6ip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399113,480,812 - 113,537,457 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9113,480,812 - 113,537,327 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm389113,651,744 - 113,708,279 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9113,651,744 - 113,708,259 (-)Ensemblmm10GRCm38
MGSCv379113,560,862 - 113,617,377 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369113,503,631 - 113,556,805 (-)NCBIMGSCv36mm8
Celera9113,360,961 - 113,417,417 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map964.03NCBI
Pdcd6ip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554211,034,843 - 1,110,438 (+)Ensembl
ChiLan1.0NW_0049554211,034,843 - 1,109,637 (+)NCBIChiLan1.0ChiLan1.0
PDCD6IP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2233,773,923 - 33,847,614 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1333,778,883 - 33,852,381 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0333,719,603 - 33,793,301 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1334,016,152 - 34,093,631 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl334,016,474 - 34,093,631 (+)EnsemblpanPan2panpan1.1
PDCD6IP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1234,112,299 - 4,199,230 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl234,112,363 - 4,196,342 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha234,154,337 - 4,240,985 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0234,374,570 - 4,462,420 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl234,374,544 - 4,462,418 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1234,207,505 - 4,294,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,339,176 - 4,426,011 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,308,530 - 4,395,465 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pdcd6ip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118190,870,278 - 190,948,263 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647324,010,935 - 24,086,846 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647324,010,942 - 24,086,836 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDCD6IP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1319,597,059 - 19,665,996 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11319,597,064 - 19,664,047 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21321,193,109 - 21,243,506 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PDCD6IP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11578,265,099 - 78,339,307 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1578,265,252 - 78,339,873 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604151,646,595 - 51,721,427 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdcd6ip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478811,772,396 - 11,845,765 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478811,772,268 - 11,849,040 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pdcd6ip
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18104,517,761 - 104,572,534 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pdcd6ip
791 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:383
Count of miRNA genes:227
Interacting mature miRNAs:288
Transcripts:ENSRNOT00000012114
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH127559  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28113,593,711 - 113,593,931 (+)MAPPERmRatBN7.2
Rnor_6.08121,918,947 - 121,919,166NCBIRnor6.0
Rnor_5.08121,234,507 - 121,234,726UniSTSRnor5.0
Celera8112,843,523 - 112,843,742UniSTS
RH 3.4 Map81197.1UniSTS
Cytogenetic Map8q32UniSTS
C76364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28113,593,843 - 113,594,060 (+)MAPPERmRatBN7.2
Rnor_6.08121,919,079 - 121,919,295NCBIRnor6.0
Rnor_5.08121,234,639 - 121,234,855UniSTSRnor5.0
Celera8112,843,655 - 112,843,871UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012114   ⟹   ENSRNOP00000012114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8122,469,223 - 122,524,993 (-)Ensembl
mRatBN7.2 Ensembl8113,590,998 - 113,646,773 (-)Ensembl
Rnor_6.0 Ensembl8121,916,185 - 121,973,125 (-)Ensembl
RefSeq Acc Id: NM_001029910   ⟹   NP_001025081
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88122,469,223 - 122,524,993 (-)NCBI
mRatBN7.28113,590,998 - 113,646,773 (-)NCBI
Dahl_SR_JrHsd8123,356,969 - 123,412,738 (-)NCBI
Lyon_Normotensive8125,462,988 - 125,518,649 (-)NCBI
Lyon_Hypertensive8123,945,791 - 124,001,557 (-)NCBI
F344_StmMcwi8115,353,999 - 115,409,775 (-)NCBI
Rnor_6.08121,916,233 - 121,973,145 (-)NCBI
Rnor_5.08121,231,793 - 121,287,105 (-)NCBI
RGSC_v3.48118,314,910 - 118,350,134 (-)RGD
Celera8112,840,809 - 112,895,775 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243997   ⟹   XP_006244059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88122,469,223 - 122,524,861 (-)NCBI
mRatBN7.28113,590,998 - 113,646,795 (-)NCBI
Rnor_6.08121,916,233 - 121,973,140 (-)NCBI
Rnor_5.08121,231,793 - 121,287,105 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001025081 (Get FASTA)   NCBI Sequence Viewer  
  XP_006244059 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF07179 (Get FASTA)   NCBI Sequence Viewer  
  EDL77006 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012114
  ENSRNOP00000012114.8
GenBank Protein Q9QZA2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001025081   ⟸   NM_001029910
- UniProtKB: A0A140TAA4 (UniProtKB/TrEMBL),   A6I3M1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244059   ⟸   XM_006243997
- Peptide Label: isoform X1
- UniProtKB: Q9QZA2 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012114   ⟸   ENSRNOT00000012114
Protein Domains
BRO1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZA2-F1-model_v2 AlphaFold Q9QZA2 1-873 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696348
Promoter ID:EPDNEW_R6872
Type:initiation region
Name:Pdcd6ip_1
Description:programmed cell death 6 interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08121,973,122 - 121,973,182EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68357 AgrOrtholog
BioCyc Gene G2FUF-28947 BioCyc
Ensembl Genes ENSRNOG00000008981 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012114 ENTREZGENE
  ENSRNOT00000012114.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.280 UniProtKB/Swiss-Prot
  alix/aip1 in complex with the ypdl late domain UniProtKB/Swiss-Prot
  alix/aip1 like domains UniProtKB/Swiss-Prot
InterPro ALIX_V_dom UniProtKB/Swiss-Prot
  BRO1_dom UniProtKB/Swiss-Prot
  BRO1_sf UniProtKB/Swiss-Prot
NCBI Gene Pdcd6ip ENTREZGENE
PANTHER PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN UniProtKB/Swiss-Prot
  PTHR23030 UniProtKB/Swiss-Prot
Pfam ALIX_LYPXL_bnd UniProtKB/Swiss-Prot
  BRO1 UniProtKB/Swiss-Prot
PhenoGen Pdcd6ip PhenoGen
PROSITE BRO1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008981 RatGTEx
SMART BRO1 UniProtKB/Swiss-Prot
TIGR TC229010
UniProt A0A140TAA4 ENTREZGENE, UniProtKB/TrEMBL
  A6I3M1 ENTREZGENE, UniProtKB/TrEMBL
  PDC6I_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Pdcd6ip  programmed cell death 6 interacting protein      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference