Cthrc1 (collagen triple helix repeat containing 1) - Rat Genome Database

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Gene: Cthrc1 (collagen triple helix repeat containing 1) Rattus norvegicus
Analyze
Symbol: Cthrc1
Name: collagen triple helix repeat containing 1
RGD ID: 628801
Description: Predicted to enable Wnt-protein binding activity; frizzled binding activity; and prostaglandin-endoperoxide synthase activity. Acts upstream of or within cell migration. Located in extracellular matrix. Human ortholog(s) of this gene implicated in Barrett's esophagus. Orthologous to human CTHRC1 (collagen triple helix repeat containing 1); PARTICIPATES IN Wnt signaling, non-canonical pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: collagen triple helix repeat-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8772,007,372 - 72,017,654 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl772,007,372 - 72,017,654 (+)EnsemblGRCr8
mRatBN7.2770,122,474 - 70,132,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl770,122,474 - 70,132,756 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx771,996,837 - 72,007,120 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0774,199,413 - 74,209,696 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0774,067,438 - 74,077,719 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd774,035,399 - 74,045,681 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive774,892,943 - 74,903,225 (+)NCBILyon_Normotensive
Lyon_Hypertensive775,032,027 - 75,042,309 (+)NCBILyon_Hypertensive
F344_StmMcwi773,654,097 - 73,664,378 (+)NCBIF344_StmMcwi
Rnor_6.0777,966,722 - 77,977,004 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl777,966,722 - 77,977,004 (+)Ensemblrn6Rnor6.0
Rnor_5.0778,271,770 - 78,282,052 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4774,630,044 - 74,640,324 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera767,178,934 - 67,189,216 (+)NCBICelera
RGSC_v3.1774,650,773 - 74,661,054 (+)NCBI
Cytogenetic Map7q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
calcium dichloride  (ISO)
camptothecin  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
furan  (EXP)
gemcitabine  (ISO)
genistein  (ISO)
glycidol  (EXP)
hexane  (EXP)
isoprenaline  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
milrinone  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalene  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (EXP)
panobinostat  (ISO)
paraquat  (EXP)
pentane-2,3-dione  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration. Pyagay P, etal., Circ Res 2005 Feb 4;96(2):261-8. Epub 2004 Dec 23.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17322174   PMID:18467647   PMID:18606138   PMID:18779865   PMID:23056600   PMID:24006456   PMID:27068509   PMID:28647773   PMID:29357417   PMID:29393342  


Genomics

Comparative Map Data
Cthrc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8772,007,372 - 72,017,654 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl772,007,372 - 72,017,654 (+)EnsemblGRCr8
mRatBN7.2770,122,474 - 70,132,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl770,122,474 - 70,132,756 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx771,996,837 - 72,007,120 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0774,199,413 - 74,209,696 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0774,067,438 - 74,077,719 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd774,035,399 - 74,045,681 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive774,892,943 - 74,903,225 (+)NCBILyon_Normotensive
Lyon_Hypertensive775,032,027 - 75,042,309 (+)NCBILyon_Hypertensive
F344_StmMcwi773,654,097 - 73,664,378 (+)NCBIF344_StmMcwi
Rnor_6.0777,966,722 - 77,977,004 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl777,966,722 - 77,977,004 (+)Ensemblrn6Rnor6.0
Rnor_5.0778,271,770 - 78,282,052 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4774,630,044 - 74,640,324 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera767,178,934 - 67,189,216 (+)NCBICelera
RGSC_v3.1774,650,773 - 74,661,054 (+)NCBI
Cytogenetic Map7q31NCBI
CTHRC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388103,371,538 - 103,382,989 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8103,371,538 - 103,382,990 (+)Ensemblhg38GRCh38
GRCh378104,383,766 - 104,395,217 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368104,452,962 - 104,464,393 (+)NCBIBuild 36Build 36hg18NCBI36
Build 348104,452,961 - 104,464,391NCBI
Celera8100,570,330 - 100,581,762 (+)NCBICelera
Cytogenetic Map8q22.3NCBI
HuRef899,584,145 - 99,595,635 (+)NCBIHuRef
CHM1_18104,424,548 - 104,436,037 (+)NCBICHM1_1
T2T-CHM13v2.08104,499,186 - 104,510,633 (+)NCBIT2T-CHM13v2.0
Cthrc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391538,940,327 - 38,950,516 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1538,940,327 - 38,950,516 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381539,076,932 - 39,087,121 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1539,076,932 - 39,087,121 (+)Ensemblmm10GRCm38
MGSCv371538,908,478 - 38,918,665 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361538,906,933 - 38,917,195 (+)NCBIMGSCv36mm8
Celera1539,563,883 - 39,573,915 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.35NCBI
Cthrc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541727,522,362 - 27,526,386 (+)Ensembl
ChiLan1.0NW_00495541727,520,420 - 27,525,907 (+)NCBIChiLan1.0ChiLan1.0
CTHRC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27120,737,645 - 120,749,201 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1896,266,097 - 96,288,939 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08100,027,417 - 100,038,945 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18102,182,944 - 102,194,445 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8102,182,944 - 102,194,445 (+)EnsemblpanPan2panpan1.1
CTHRC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1134,801,049 - 4,811,565 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl134,805,577 - 4,811,282 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha134,804,416 - 4,815,108 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0134,964,918 - 4,975,641 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl134,964,661 - 4,975,365 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1134,805,272 - 4,815,967 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0134,923,227 - 4,933,925 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0134,935,964 - 4,946,667 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cthrc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530332,955,116 - 32,965,990 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647040,377,835 - 40,392,225 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647040,381,215 - 40,392,105 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTHRC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl433,759,542 - 33,771,582 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1433,759,541 - 33,771,625 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2436,579,490 - 36,591,565 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTHRC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1898,227,661 - 98,239,984 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl898,227,705 - 98,240,753 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603942,361,868 - 42,374,150 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cthrc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476319,917,169 - 19,925,896 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476319,917,199 - 19,925,824 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cthrc1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11212,092,701 - 212,103,049 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cthrc1
36 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:34
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000006142
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)771103011106126789Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 143 86 85 54 39 54 6 286 139 11 122 69 91 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000006142   ⟹   ENSRNOP00000006142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl772,007,372 - 72,017,654 (+)Ensembl
mRatBN7.2 Ensembl770,122,474 - 70,132,756 (+)Ensembl
Rnor_6.0 Ensembl777,966,722 - 77,977,004 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102466   ⟹   ENSRNOP00000086689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl772,007,486 - 72,017,654 (+)Ensembl
mRatBN7.2 Ensembl770,122,588 - 70,132,756 (+)Ensembl
RefSeq Acc Id: NM_001271300   ⟹   NP_001258229
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8772,007,372 - 72,017,654 (+)NCBI
mRatBN7.2770,122,474 - 70,132,756 (+)NCBI
Dahl_SR_JrHsd774,035,399 - 74,045,681 (+)NCBI
Lyon_Normotensive774,892,943 - 74,903,225 (+)NCBI
Lyon_Hypertensive775,032,027 - 75,042,309 (+)NCBI
F344_StmMcwi773,654,097 - 73,664,378 (+)NCBI
Rnor_6.0777,966,722 - 77,977,004 (+)NCBI
Rnor_5.0778,271,770 - 78,282,052 (-)NCBI
Celera767,178,934 - 67,189,216 (+)NCBI
Sequence:
RefSeq Acc Id: NM_172333   ⟹   NP_758836
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8772,007,372 - 72,017,654 (+)NCBI
mRatBN7.2770,122,474 - 70,132,756 (+)NCBI
Dahl_SR_JrHsd774,035,399 - 74,045,681 (+)NCBI
Lyon_Normotensive774,892,943 - 74,903,225 (+)NCBI
Lyon_Hypertensive775,032,027 - 75,042,309 (+)NCBI
F344_StmMcwi773,654,097 - 73,664,378 (+)NCBI
Rnor_6.0777,966,722 - 77,977,004 (+)NCBI
Rnor_5.0778,271,770 - 78,282,052 (-)NCBI
RGSC_v3.4774,630,044 - 74,640,324 (+)RGD
Celera767,178,934 - 67,189,216 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001258229 (Get FASTA)   NCBI Sequence Viewer  
  NP_758836 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAN15748 (Get FASTA)   NCBI Sequence Viewer  
  EDM16354 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006142
GenBank Protein Q8CG08 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_758836   ⟸   NM_172333
- Peptide Label: isoform 1 precursor
- UniProtKB: Q8CG08 (UniProtKB/Swiss-Prot),   A0A8L2Q207 (UniProtKB/TrEMBL),   A6HR68 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258229   ⟸   NM_001271300
- Peptide Label: isoform 2 precursor
- UniProtKB: A0A8L2Q207 (UniProtKB/TrEMBL),   A6HR68 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006142   ⟸   ENSRNOT00000006142
Ensembl Acc Id: ENSRNOP00000086689   ⟸   ENSRNOT00000102466
Protein Domains
Collagen-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CG08-F1-model_v2 AlphaFold Q8CG08 1-245 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695305
Promoter ID:EPDNEW_R5830
Type:initiation region
Name:Cthrc1_1
Description:collagen triple helix repeat containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0777,966,765 - 77,966,825EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628801 AgrOrtholog
BioCyc Gene G2FUF-33577 BioCyc
Ensembl Genes ENSRNOG00000004578 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000006142 ENTREZGENE
KEGG Report rno:282836 UniProtKB/Swiss-Prot
NCBI Gene 282836 ENTREZGENE
PhenoGen Cthrc1 PhenoGen
RatGTEx ENSRNOG00000004578 RatGTEx
UniProt A0A8I6A6B3_RAT UniProtKB/TrEMBL
  A0A8L2Q207 ENTREZGENE, UniProtKB/TrEMBL
  A6HR68 ENTREZGENE, UniProtKB/TrEMBL
  CTHR1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Cthrc1  collagen triple helix repeat containing 1      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Cthrc1  collagen triple helix repeat containing 1      Symbol and Name status set to provisional 70820 PROVISIONAL