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Gene: Slc12a8 (solute carrier family 12, member 8) Rattus norvegicus

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Symbol:

Slc12a8

Name:

solute carrier family 12, member 8

RGD ID:

628730

Description:

Predicted to enable potassium:chloride symporter activity. Predicted to be involved in several processes, including chloride ion homeostasis; monoatomic ion transmembrane transport; and potassium ion homeostasis. Predicted to be located in membrane. Orthologous to human SLC12A8 (solute carrier family 12 member 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cation-chloride cotransporter 9; Ccc9; solute carrier family 12 (potassium/chloride transporters), member 8; solute carrier family 12 member 8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC12A8 (solute carrier family 12 member 8)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Slc12a8 (solute carrier family 12 (potassium/chloride transporters), member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc12a8 (solute carrier family 12 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC12A8 (solute carrier family 12 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC12A8 (solute carrier family 12 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc12a8 (solute carrier family 12 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC12A8 (solute carrier family 12 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103228134 (solute carrier family 12 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc12a8 (solute carrier family 12 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Slc12a8 (solute carrier family 12 member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SLC12A8 (solute carrier family 12 member 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc12a8 (solute carrier family 12 (potassium/chloride transporters), member 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc12a8 (solute carrier family 12 member 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12773	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F10E7.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc12a8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc12a8	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	80,622,000 - 80,771,674 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	80,622,000 - 80,771,659 (-)	Ensembl				GRCr8
mRatBN7.2	11	67,116,876 - 67,266,548 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	67,116,877 - 67,266,834 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	75,949,593 - 76,099,488 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	68,611,466 - 68,761,340 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	67,642,062 - 67,791,952 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	82,530,019 - 82,679,910 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	80,715,022 - 80,864,911 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	81,659,650 - 81,809,542 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	80,489,626 - 80,639,499 (-)	NCBI		F344_StmMcwi
Rnor_6.0	11	70,344,771 - 70,499,202 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	70,344,797 - 70,499,200 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	73,432,330 - 73,586,317 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	68,934,104 - 69,087,168 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	66,567,029 - 66,714,564 (-)	NCBI		Celera
RGSC_v3.1	11	68,991,693 - 69,144,757 (-)	NCBI
Cytogenetic Map	11	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

chlorpromazine (EXP)

choline (ISO)

chromium(6+) (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

cocaine (EXP)

copper atom (EXP)

copper(0) (EXP)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (EXP,ISO)

dioxygen (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

entinostat (ISO)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

furan (EXP)

gallic acid (ISO)

glycidol (EXP)

GSK-J4 (ISO)

hydrogen peroxide (ISO)

ifosfamide (ISO)

L-methionine (ISO)

lead diacetate (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

metformin (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

naled (ISO)

nickel atom (ISO)

NMN zwitterion (ISO)

paracetamol (ISO)

PCB138 (ISO)

permethrin (EXP)

phenethyl caffeate (EXP)

potassium chromate (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

sunitinib (ISO)

temozolomide (ISO)

theophylline (ISO)

titanium dioxide (ISO)

tributylstannane (ISO)

trichloroethene (EXP)

triptonide (ISO)

troglitazone (EXP)

valproic acid (ISO)

XL147 (ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell volume homeostasis (IBA)

chloride ion homeostasis (IBA)

chloride transmembrane transport (IBA,IEA)

monoatomic ion transport (IEA)

potassium ion homeostasis (IBA)

potassium ion import across plasma membrane (IBA)

potassium ion transport (IEA)

transmembrane transport (IEA)

Cellular Component

membrane (IEA)

Molecular Function

chloride:monoatomic cation symporter activity (IEA)

potassium:chloride symporter activity (IBA)

protein binding (ISO)

symporter activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Slc12a8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	80,622,000 - 80,771,674 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	80,622,000 - 80,771,659 (-)	Ensembl				GRCr8
mRatBN7.2	11	67,116,876 - 67,266,548 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	67,116,877 - 67,266,834 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	75,949,593 - 76,099,488 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	68,611,466 - 68,761,340 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	67,642,062 - 67,791,952 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	82,530,019 - 82,679,910 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	80,715,022 - 80,864,911 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	81,659,650 - 81,809,542 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	80,489,626 - 80,639,499 (-)	NCBI		F344_StmMcwi
Rnor_6.0	11	70,344,771 - 70,499,202 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	70,344,797 - 70,499,200 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	73,432,330 - 73,586,317 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	68,934,104 - 69,087,168 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	66,567,029 - 66,714,564 (-)	NCBI		Celera
RGSC_v3.1	11	68,991,693 - 69,144,757 (-)	NCBI
Cytogenetic Map	11	q22	NCBI

SLC12A8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	125,082,644 - 125,212,748 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	125,082,636 - 125,213,229 (-)	Ensembl			hg38	GRCh38
GRCh37	3	124,801,488 - 124,931,592 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	126,284,170 - 126,414,299 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	126,284,171 - 126,414,273	NCBI
Celera	3	123,208,830 - 123,340,801 (-)	NCBI		Celera
Cytogenetic Map	3	q21.2	NCBI
HuRef	3	122,175,576 - 122,307,515 (-)	NCBI		HuRef
CHM1_1	3	124,764,695 - 124,894,611 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	127,808,303 - 127,940,353 (-)	NCBI		T2T-CHM13v2.0

Slc12a8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	33,337,440 - 33,484,508 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	33,337,698 - 33,484,505 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	33,517,328 - 33,664,138 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	33,517,328 - 33,664,135 (+)	Ensembl			mm10	GRCm38
MGSCv37	16	33,518,415 - 33,664,221 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	33,438,085 - 33,583,150 (+)	NCBI		MGSCv36	mm8
Celera	16	34,001,716 - 34,147,712 (+)	NCBI		Celera
Cytogenetic Map	16	B3	NCBI
cM Map	16	24.12	NCBI

Slc12a8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	24,137,228 - 24,284,070 (-)	Ensembl
ChiLan1.0	NW_004955427	24,137,420 - 24,284,485 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC12A8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	123,078,737 - 123,209,450 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	123,083,006 - 123,214,229 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	122,214,558 - 122,344,797 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	129,080,749 - 129,210,870 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	129,080,749 - 129,210,872 (-)	Ensembl			panPan2	panpan1.1

SLC12A8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	28,085,345 - 28,200,779 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	28,085,350 - 28,214,022 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	28,108,177 - 28,241,143 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	28,318,223 - 28,450,846 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	28,318,226 - 28,451,230 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	28,117,173 - 28,249,376 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	28,161,405 - 28,293,994 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	28,781,397 - 28,913,009 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Slc12a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	126,211,080 - 126,329,094 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936725	100,823 - 237,223 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936725	100,780 - 237,525 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC12A8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	135,105,896 - 135,249,120 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	135,105,723 - 135,249,124 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	144,631,230 - 144,751,929 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103228134
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	55,623,961 - 55,754,969 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	55,646,406 - 55,754,209 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	110,556,797 - 110,658,171 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc12a8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	1,113,489 - 1,259,344 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624731	1,114,079 - 1,259,832 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Slc12a8
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	18,327,819 - 18,453,980 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Slc12a8
866 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	281
Count of miRNA genes:	146
Interacting mature miRNAs:	167
Transcripts:	ENSRNOT00000002439, ENSRNOT00000040167
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	22524746	82951192	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	46443168	91443168	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	73308487	96070872	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	58928336	99753367	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	32943067	89836615	Rat
1549848	Bvd6	Brain ventricular dilatation QTL 6	3.1	0.0001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	79618519	99753367	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	36428416	81428416	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	73850894	99753367	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	54415391	96071021	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	58931822	92356038	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	57754837	96071021	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	20193549	96351019	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	36749459	81749459	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	67962184	99753367	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	36749459	81749459	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	68599321	96497754	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	69855943	99753367	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	73308315	99753367	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	51071021	96071021	Rat

Markers in Region

RH128794

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	67,116,935 - 67,117,132 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	70,344,831 - 70,345,027	NCBI	Rnor6.0
Rnor_5.0	11	73,432,390 - 73,432,586	UniSTS	Rnor5.0
RGSC_v3.4	11	68,934,164 - 68,934,360	UniSTS	RGSC3.4
Celera	11	66,567,089 - 66,567,285	UniSTS
RH 3.4 Map	11	411.6	UniSTS
Cytogenetic Map	11	q22	UniSTS

BM385725

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	67,185,172 - 67,185,364 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	70,413,081 - 70,413,272	NCBI	Rnor6.0
Rnor_5.0	11	73,500,198 - 73,500,389	UniSTS	Rnor5.0
RGSC_v3.4	11	69,003,012 - 69,003,203	UniSTS	RGSC3.4
Celera	11	66,634,906 - 66,635,097	UniSTS
RH 3.4 Map	11	407.7	UniSTS
Cytogenetic Map	11	q22	UniSTS

AU049215

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Celera	11	66,605,880 - 66,606,004	UniSTS
Cytogenetic Map	11	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	66	146	81	80	49	75	49	6	327	173	10	126	81	92	31	12	12

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_153625	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248423	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB024430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB024431	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC110981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000002439 ⟹ ENSRNOP00000002439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	80,622,000 - 80,770,915 (-)	Ensembl
mRatBN7.2 Ensembl	11	67,116,877 - 67,265,804 (-)	Ensembl
Rnor_6.0 Ensembl	11	70,344,797 - 70,499,200 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000040167 ⟹ ENSRNOP00000045345

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	80,622,000 - 80,751,797 (-)	Ensembl
mRatBN7.2 Ensembl	11	67,116,877 - 67,246,688 (-)	Ensembl
Rnor_6.0 Ensembl	11	70,345,038 - 70,498,391 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086495 ⟹ ENSRNOP00000072100

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	80,622,000 - 80,770,915 (-)	Ensembl
mRatBN7.2 Ensembl	11	67,116,877 - 67,266,834 (-)	Ensembl
Rnor_6.0 Ensembl	11	70,345,128 - 70,498,437 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108813 ⟹ ENSRNOP00000081818

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	80,622,000 - 80,771,659 (-)	Ensembl
mRatBN7.2 Ensembl	11	67,116,877 - 67,265,804 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119564 ⟹ ENSRNOP00000091705

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	80,622,000 - 80,770,915 (-)	Ensembl
mRatBN7.2 Ensembl	11	67,116,877 - 67,265,804 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000165564 ⟹ ENSRNOP00000104872

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	80,625,608 - 80,770,915 (-)	Ensembl

RefSeq Acc Id:

NM_153625 ⟹ NP_705889

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	80,622,000 - 80,770,915 (-)	NCBI
mRatBN7.2	11	67,116,876 - 67,265,804 (-)	NCBI
Dahl_SR_JrHsd	11	82,530,019 - 82,679,910 (-)	NCBI
Lyon_Normotensive	11	80,715,022 - 80,864,911 (-)	NCBI
Lyon_Hypertensive	11	81,659,650 - 81,809,542 (-)	NCBI
F344_StmMcwi	11	80,489,626 - 80,639,499 (-)	NCBI
Rnor_6.0	11	70,344,771 - 70,498,437 (-)	NCBI
Rnor_5.0	11	73,432,330 - 73,586,317 (-)	NCBI
RGSC_v3.4	11	68,934,104 - 69,087,168 (-)	RGD
Celera	11	66,567,029 - 66,714,564 (-)	RGD

Sequence:

show sequence

AGAGGGNCTCCCCATCTAGAGGATCAGAACCTCACTTGCTGAAGAATGGCCCAGAGGTCTCCAC
AGGAACTTTTCCACGAGGCAGCCCAGCAGGGCGTCCTGGCCCGGTCCCAGCCCTGGTGGAAGAT
CCAGCTGTTCATGTGGGAGCCAGTACTATTTGGGACCTGGGATGGTGTGTTCACATCCTGCATG
ATCAACATTTTCGGGGTTGTCCTTTTCTTGAGGACCGGCTGGCTGGTGGGAAACACGGGTGTAC
TCCTGGGCTTGCTCCTTGTGTCCTTTGTCATCCTCGTGGCCCTCATCACCGTGCTGTCTGGCAT
TGGCGTCGCAGAGCATGGCTGGATGGGCAGTGGCGGCGTCTACTCCATGATCTCCTCCGTGCTT
GGTGGACAGATGGGAGGCACTGTAGGGCTGCTGTATGTATTTGGACAGTGTGTTGCAGGTGCCA
TGTACCTCACTGGCTTTGCCGAGTCCATCTCAGATCTGCTGGGTCTCGGGAACATCTGGGCTGT
TCGAGGAATCTCCGTGGCGGTGCTTCTGGCTTTGCTGGGCATCAACCTGGCAGGCGTCAAGTGG
ATAATCCGCCTCCAGCTGCTGCTGCTGTCCCTGCTGGCTGTCTCAACCCTGGACTTTGTGGTGG
GCTCTTTCACCCACCTGGACCCAGAGCATGGCTTTATTGGATACTCCCCAGAACTGCTACAGAG
CAACATCCTGCCTGAGTACAGCCCCGGGGAGTCATTCTTCACTGTGTTTGGGGTGTTCTTCCCC
GCAGCTACAGGAGTCATGGCTGGCTTCAACATGGGAGGAGACCTGAGGGAGCCTGCTGACCAGC
ATACCCCTAGGCTCCCTAGCAGCTGTTGGGTATCTCGTGGTTTCTCTAACATCATCTTTGCCTT
CCTGCTTGGTGCCGTCTGTACCCGAGAGGCCCTCCGCTCTGACTTCCTGATAGCTGAAAAGGTA
TCTCTGGTTGGTTTCCTCTTCCTGTTGGGCTTGTACATCTCATCCCTGGCTTCCTGTATGGGGG
GACTCTATGGAGCCCCCCGGATCCTGCAGTGCATCGCCCAGGACAAAGTGATTCCAGCTCTCGC
CTTTCTGGGGAACGGGAAAGGGCCAAATAAAACACCCGTAGCAGCCATCTGCCTGACCAGCTTG
GTGACCATGGCCTTTGTCCTTGTGGGTCAGGTGAATGTTCTGGCGCCCGTGGTCACCATCAACT
TCATGCTGACCTACATCGCAGTGGACTACTCTTACTTCGCCCTCTCCATGGCTCACTGCGGCCT
CGCCCAGTCTCCTGAGCCCATGCCCAGACAAGGCCCGGATGCTCTGCACTGCTCTGAGCACCTG
CTCCAGGACAAGGCTCCCAGCTATGGCTCAGACACCCCTGCCGGAAGCCTCTCTGAAGGTACCC
TGCTGGAGTTCACCAAGGACATGGATCAGCTCCTCCAGCCAATAGGGGGACTTGAGAGTCAGCC
TAGGTCAAGAGAAGTTAACCAGGTCCTAAAGAGTCAGAAGCACAAGTGTAAGAAAGACGCCAAG
CAAACCCTACAAGATAGCTTCCTCTTGGATGCTGAGTCTCCTTTGTCCTTTTCTATGGGGGCCT
CTGAGAGGTTGTCGGTTGCCTCCTGTGGAGAGCAAGAGTCCTATCAGAACCAGCAGACTTCTAG
GAGTGAATCACATGACCATCTTGTCCCTGATCTGTGTACCCAGCCTAGAGCGAACGGAGAAGAT
TTCTTTCTGAAATGCAGACTTCAGGAACAGCAGGTCCAGAGGAGACCAAGTGCTTTCTATGTTT
GCATGTGTAACCCCTGGGTCTCCCTGTTAGGGGCTCTTGCATCCCTGCTCATCATGTTTGTGAT
CCAGTGGCTCTATACCCTAGCTAGCATGGGTGTTGCTGCCCTTGTGTACCTCTACATTGGCCAG
GCCAGTCCAGGCCTTTACCTCGGATCAGCATCAAACTTCAGCTTTTTCCAATGGATGAAGTCCT
TCTTGGTCCCCTCCTGCAGGAGCCTGAGATCCACCCGGGAGCAAATCATCTTGGCACCGTCCCC
AGCCAAGGTTGACATGGCAATGACTCAAGCTTACCCAGGACAATGGCAGACTTCGGCCACCCGA
GAACGGTACCACCGGTCTTCCTTCCTGAGTCGGGAACAGCTGATGCCTCCCTACTAGACCCTCG
CTGGAGCCCTCCTTTCTAGAAGTTGCTGTGGAGCTGAGGGACCCAAACCTCAGAACCTTTGGAA
GTTGCTTCTACCAATAAGAAATCCCAAGACTGGTCTTCCCACCACAGCCTTGGACACCGGAAAT
CACATTCCAGACACTAGGCATGGCCATGGCTTCCACGTGCTTCAGGAGCCCACAGGCCACCAGG
ATAATGTAAAAAAACAAAATGAGAGTTCTTATTTTAAGAGCCATAATGAATACTTCTTTTTAAT
TTTAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006248423 ⟹ XP_006248485

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	80,622,000 - 80,771,674 (-)	NCBI
mRatBN7.2	11	67,116,876 - 67,266,548 (-)	NCBI
Rnor_6.0	11	70,344,771 - 70,499,202 (-)	NCBI
Rnor_5.0	11	73,432,330 - 73,586,317 (-)	NCBI

Sequence:

show sequence

GCGGGCGTGGCCTCCGGAGCCCGGGGAGGTGCAGGTGAAGGTCCGGGTACTGCTCCGCGGAGGG
GAAGAATGGCCAGGGTCCGGAGGACCTGACCCTGGTGCCCAGAACCTCATCCCGCAGCCCCCAG
ATCTTCTTAGGAGTGGTCTCCCCATCTAGAGTATCAGAACCTCACTTCCTGAAGAATGGCCCAG
AGGTCTCCACAGGAACTTTTCCACGAGGCAGCCCAGCAGGGCGCCCTGGCCCGGTCCCAGCCCT
GGTGGAAGATCCAGCTGTTCATGTGGGAGCCAGTACTATTTGGGACCTGGGATGGTGTGTTCAC
ATCCTGCATGATCAACATTTTCGGGGTTGTCCTTTTCTTGAGGACCGGCTGGCTGGTGGGAAAC
ACGGGTGTACTCCTGGGCTTGCTCCTTGTGTCCTTTGTCATCCTCGTGGCCCTCATCACCGTGC
TGTCTGGCATTGGCGTCGCAGAGCATGGCTGGATGGGCAGTGGCGGCGTCTACTCCATGATCTC
CTCCGTGCTTGGTGGACAGATGGGAGGCACTGTAGGGCTGCTGTATGTATTTGGACAGTGTGTT
GCAGGTGCCATGTACCTCACTGGCTTTGCCGAGTCCATCTCAGATCTGCTGGGTCTCGGGAACA
TCTGGGCTGTTCGAGGAATCTCCGTGGCGGTGCTTCTGGCTTTGCTGGGCATCAACCTGGCAGG
CGTCAAGTGGATAATCCGCCTCCAGCTGCTGCTGCTGTCCCTGCTGGCTGTCTCAACCCTGGAC
TTTGTGGTGGGCTCTTTCACCCACCTGGACCCAGAGCATGGCTTTATTGGATACTCCCCAGAAC
TGCTACAGAGCAACATCCTGCCTGAGTACAGCCCCGGGGAGTCATTCTTCACTGTGTTTGGGGT
GTTCTTCCCCGCAGCTACAGGAGTCATGGCTGGCTTCAACATGGGAGGAGACCTGAGGGAGCCT
GCTGACAGCATACCCCTAGGCTCCCTAGCAGCTGTTGGTATCTCGTGGTTTCTCTACATCATCT
TTGCCTTCCTGCTTGGTGCCGTCTGTACCCGAGAGGCCCTCCGCTCTGACTTCCTGATAGCTGA
AAAGGTATCTCTGGTTGGTTTCCTCTTCCTGTTGGGCTTGTACATCTCATCCCTGGCTTCCTGT
ATGGGGGGACTCTATGGAGCCCCCCGGATCCTGCAGTGCATCGCCCAGGACAAAGTGATTCCAG
CTCTCGCCTTTCTGGGGAACGGGAAAGGGCCAAATAAAACACCCGTAGCAGCCATCTGCCTGAC
CAGCTTGGTGACCATGGCCTTTGTCCTTGTGGGTCAGGTGAATGTTCTGGCGCCCGTGGTCACC
ATCAACTTCATGCTGACCTACATCGCAGTGGACTACTCTTACTTCGCCCTCTCCATGGCTCACT
GCGGCCTCGCCCAGTCTCCTGAGCCCATGCCCAGACAAGGCCCGGATGCTCTGCACTGCTCTGA
GCACCTGCTCCAGGACAAGGCTCCCAGCTATGGCTCAGACACCCCTGCCGGAAGCCTCTCTGAA
GGTACCCTGCTGGAGTTCACCAAGGACATGGATCAGCTCCTCCAGCCAATAGGGGGACTTGAGA
GTCAGCCTAGGTCAAGAGACGTTAACCAGGTCCTAAAGAGTCAGAAGCACAAGTGTAAGAAAGA
CGCCAAGCAAACCCTACAAGATAGCTTCCTCTTGGATGCTGAGTCTCCTTTGTCCTTTTCTATG
GGGGCCTCTGAGAGGTTGTCGGTTGCCTCCTGTGGAGAGCAAGAGTCCTATCAGAACCAGCAGA
CTTCTAGGAGTGAATCACATGACCATCTTGTCCCTGATCTGTGTACCCAGCCTAGAGCGAACGG
AGAAGATTTCTTTCTGAAATGCAGACTTCAGGAACAGCAGGTCCAGAGGAGACCAAGTGCTTTC
TATGTTTGCATGTGTAACCCCTGGGTCTCCCTGTTAGGGGCTCTTGCATCCCTGCTCATCATGT
TTGTGATCCAGTGGCTCTATACCCTAGCTAGCATGGGTGTTGCTGCCCTTGTGTACCTCTACAT
TGGCCAGGCCAGTCCAGGCCTTTACCTCGGATCAGCATCAAACTTCAGCTTTTTCCAATGGATG
AAGTCCTTCTTGGTCCCCTCCTGCAGGAGCCTGAGATCCACCCGGGAGCAAATCATCTTGGCAC
CGTCCCCAGCCAAGGTTGACATGGCAATGACTCAGCTTACCCAGGACAATGCAGACTTCGCCAC
CCGAGATCGTTACCACCGCTCTTCCTTCCTGAGTCGGGAACAGCTGATGCCTCCCTACTAGACC
CTCGCTGGAGCCCTCCTTTCTAGAAGCTGCTGTGGAGCTGAGGGACCCAAACCTCAGAACCTTT
GGAAGTTGCTTCTACCAATAAGAAATCCCAAGACTGGTCTTCCCACCACAGCCTTGGACACCGG
AAATCACATTCCAGACACTAGGCATGGCCATGGCTTCCACGTGCTTGAGGAGCCCACAGGCCAC
CAGGATAATGTAAAAAAACAAAATGAGAGTTCTTATTCTAAGAGCCATAATAAATACTTCTTTT
TAATTTTA

hide sequence

RefSeq Acc Id:

XM_039088051 ⟹ XP_038943979

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	80,622,000 - 80,770,955 (-)	NCBI
mRatBN7.2	11	67,117,179 - 67,265,796 (-)	NCBI

RefSeq Acc Id:

XM_039088052 ⟹ XP_038943980

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	80,622,000 - 80,704,856 (-)	NCBI
mRatBN7.2	11	67,116,876 - 67,199,669 (-)	NCBI

RefSeq Acc Id:

XM_063270314 ⟹ XP_063126384

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	80,622,000 - 80,771,674 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_705889	(Get FASTA)	NCBI Sequence Viewer
	XP_006248485	(Get FASTA)	NCBI Sequence Viewer
	XP_038943979	(Get FASTA)	NCBI Sequence Viewer
	XP_038943980	(Get FASTA)	NCBI Sequence Viewer
	XP_063126384	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAC20264	(Get FASTA)	NCBI Sequence Viewer
	BAC20265	(Get FASTA)	NCBI Sequence Viewer
	EDM11357	(Get FASTA)	NCBI Sequence Viewer
	EDM11358	(Get FASTA)	NCBI Sequence Viewer
	EDM11359	(Get FASTA)	NCBI Sequence Viewer
	EDM11360	(Get FASTA)	NCBI Sequence Viewer
	EDM11361	(Get FASTA)	NCBI Sequence Viewer
	EDM11362	(Get FASTA)	NCBI Sequence Viewer
	EDM11363	(Get FASTA)	NCBI Sequence Viewer
	EDM11364	(Get FASTA)	NCBI Sequence Viewer
	EDM11365	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002439
	ENSRNOP00000081818
GenBank Protein	Q8CJI3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_705889 ⟸ NM_153625

- UniProtKB:

Q8CJI3 (UniProtKB/Swiss-Prot), Q8CJI2 (UniProtKB/Swiss-Prot), F1M7M6 (UniProtKB/TrEMBL), A6IRK4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAQRSPQELFHEAAQQGVLARSQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWL
VGNTGVLLGLLLVSFVILVALITVLSGIGVAEHGWMGSGGVYSMISSVLGGQMGGTVGLLYVFG
QCVAGAMYLTGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLSLLAVS
TLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDL
REPADQHTPRLPSSCWVSRGFSNIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISS
LASCMGGLYGAPRILQCIAQDKVIPALAFLGNGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLA
PVVTINFMLTYIAVDYSYFALSMAHCGLAQSPEPMPRQGPDALHCSEHLLQDKAPSYGSDTPAG
SLSEGTLLEFTKDMDQLLQPIGGLESQPRSREVNQVLKSQKHKCKKDAKQTLQDSFLLDAESPL
SFSMGASERLSVASCGEQESYQNQQTSRSESHDHLVPDLCTQPRANGEDFFLKCRLQEQQVQRR
PSAFYVCMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYLYIGQASPGLYLGSASNFSF
FQWMKSFLVPSCRSLRSTREQIILAPSPAKVDMAMTQAYPGQWQTSATRERYHRSSFLSREQLM
PPY

hide sequence

RefSeq Acc Id:	XP_006248485 ⟸ XM_006248423
- Peptide Label:	isoform X1
- UniProtKB:	Q8CJI3 (UniProtKB/Swiss-Prot), Q8CJI2 (UniProtKB/Swiss-Prot), F1M7M6 (UniProtKB/TrEMBL), A6IRK4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAQRSPQELFHEAAQQGALARSQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWL VGNTGVLLGLLLVSFVILVALITVLSGIGVAEHGWMGSGGVYSMISSVLGGQMGGTVGLLYVFG QCVAGAMYLTGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLSLLAVS TLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDL REPADSIPLGSLAAVGISWFLYIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSL ASCMGGLYGAPRILQCIAQDKVIPALAFLGNGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLAP VVTINFMLTYIAVDYSYFALSMAHCGLAQSPEPMPRQGPDALHCSEHLLQDKAPSYGSDTPAGS LSEGTLLEFTKDMDQLLQPIGGLESQPRSRDVNQVLKSQKHKCKKDAKQTLQDSFLLDAESPLS FSMGASERLSVASCGEQESYQNQQTSRSESHDHLVPDLCTQPRANGEDFFLKCRLQEQQVQRRP SAFYVCMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYLYIGQASPGLYLGSASNFSFF QWMKSFLVPSCRSLRSTREQIILAPSPAKVDMAMTQLTQDNADFATRDRYHRSSFLSREQLMPP Y hide sequence

Ensembl Acc Id:

ENSRNOP00000002439 ⟸ ENSRNOT00000002439

Ensembl Acc Id:

ENSRNOP00000072100 ⟸ ENSRNOT00000086495

Ensembl Acc Id:

ENSRNOP00000045345 ⟸ ENSRNOT00000040167

RefSeq Acc Id:	XP_038943980 ⟸ XM_039088052
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2K244 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038943979 ⟸ XM_039088051
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6G6I7 (UniProtKB/TrEMBL), A6IRK9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000081818 ⟸ ENSRNOT00000108813

Ensembl Acc Id:

ENSRNOP00000091705 ⟸ ENSRNOT00000119564

RefSeq Acc Id:	XP_063126384 ⟸ XM_063270314
- Peptide Label:	isoform X1
- UniProtKB:	Q8CJI3 (UniProtKB/Swiss-Prot), Q8CJI2 (UniProtKB/Swiss-Prot), A6IRK4 (UniProtKB/TrEMBL), F1M7M6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000104872 ⟸ ENSRNOT00000165564

Protein Domains

Amino acid permease/ SLC12A

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8CJI3-F1-model_v2	AlphaFold	Q8CJI3	1-707	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698205

Promoter ID:

EPDNEW_R8724

Type:

single initiation site

Name:

Slc12a8_1

Description:

solute carrier family 12, member 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	70,498,513 - 70,498,573	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628730	AgrOrtholog
BioCyc Gene	G2FUF-21130	BioCyc
Ensembl Genes	ENSRNOG00000001792	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000002439	ENTREZGENE
	ENSRNOT00000108813	ENTREZGENE
Gene3D-CATH	Amino acid/polyamine transporter I	UniProtKB/Swiss-Prot
InterPro	AA-permease/SLC12A_dom	UniProtKB/Swiss-Prot
	SLC12A_fam	UniProtKB/Swiss-Prot
KEGG Report	rno:266733	UniProtKB/Swiss-Prot
NCBI Gene	266733	ENTREZGENE
PANTHER	PTHR11827	UniProtKB/Swiss-Prot
	PTHR11827:SF6	UniProtKB/Swiss-Prot
Pfam	AA_permease	UniProtKB/Swiss-Prot
PhenoGen	Slc12a8	PhenoGen
RatGTEx	ENSRNOG00000001792	RatGTEx
UniProt	A0A0G2K244	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AE65_RAT	UniProtKB/TrEMBL
	A0A8I6G6I7	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LRU3_RAT	UniProtKB/TrEMBL
	A6IRK4	ENTREZGENE, UniProtKB/TrEMBL
	A6IRK5_RAT	UniProtKB/TrEMBL
	A6IRK6_RAT	UniProtKB/TrEMBL
	A6IRK7_RAT	UniProtKB/TrEMBL
	A6IRK8_RAT	UniProtKB/TrEMBL
	A6IRK9	ENTREZGENE, UniProtKB/TrEMBL
	A6IRL0_RAT	UniProtKB/TrEMBL
	A6IRL1_RAT	UniProtKB/TrEMBL
	A6IRL2_RAT	UniProtKB/TrEMBL
	D4AAY5_RAT	UniProtKB/TrEMBL
	F1M7M6	ENTREZGENE, UniProtKB/TrEMBL
	Q8CJI2	ENTREZGENE
	Q8CJI3	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q8CJI2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-08-02	Slc12a8	solute carrier family 12, member 8	Slc12a8	solute carrier family 12 (potassium/chloride transporters), member 8	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Slc12a8	solute carrier family 12 (potassium/chloride transporters), member 8		cation-chloride cotransporter 9	Name updated	1299863	APPROVED
2004-09-10	Slc12a8	cation-chloride cotransporter 9	Ccc9		Symbol and Name updated	1299863	APPROVED
2003-02-27	Ccc9	cation-chloride cotransporter 9			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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