Afm (afamin) - Rat Genome Database

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Gene: Afm (afamin) Rattus norvegicus
Analyze
Symbol: Afm
Name: afamin
RGD ID: 628614
Description: Predicted to enable vitamin E binding activity. Predicted to be involved in several processes, including protein stabilization; protein transport within extracellular region; and vitamin transport. Located in extracellular space. Orthologous to human AFM (afamin); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha albumin; alpha-Alb; alpha-albumin
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81417,815,194 - 17,848,042 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1417,815,194 - 17,848,039 (-)EnsemblGRCr8
mRatBN7.21417,531,022 - 17,563,868 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,531,024 - 17,563,870 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1417,525,337 - 17,550,140 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01418,844,268 - 18,869,067 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01417,536,413 - 17,568,193 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01419,078,678 - 19,132,212 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1419,078,680 - 19,132,208 (-)Ensemblrn6Rnor6.0
Rnor_5.01419,035,336 - 19,039,510 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01418,988,809 - 19,008,149 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41419,049,664 - 19,082,977 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1416,899,392 - 16,930,240 (-)NCBICelera
RGSC_v3.11419,049,663 - 19,082,977 (-)NCBI
Cytogenetic Map14p22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
chenodeoxycholic acid  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
doxorubicin  (EXP)
endosulfan  (ISO)
flutamide  (EXP)
fumonisin B1  (ISO)
glafenine  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hexadecanoic acid  (ISO)
L-ethionine  (EXP)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
olanzapine  (ISO)
omeprazole  (EXP)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rotenone  (EXP)
sodium arsenite  (ISO)
Sunset Yellow FCF  (ISO)
tartrazine  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
Triptolide  (EXP,ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
metal ion binding  (IEA)
protein binding  (ISO)
vitamin E binding  (IBA,IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. New albumin gene 3' adjacent to the alpha 1-fetoprotein locus. Belanger L, etal., J Biol Chem 1994 Feb 25;269(8):5481-4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes. Hinojos CA, etal., Hypertension 2005 Apr;45(4):698-704. Epub 2005 Feb 14.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12463752   PMID:12477932   PMID:15952736   PMID:16502470   PMID:19046407   PMID:22516433   PMID:23376485   PMID:23533145   PMID:26902720  


Genomics

Comparative Map Data
Afm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81417,815,194 - 17,848,042 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1417,815,194 - 17,848,039 (-)EnsemblGRCr8
mRatBN7.21417,531,022 - 17,563,868 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,531,024 - 17,563,870 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1417,525,337 - 17,550,140 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01418,844,268 - 18,869,067 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01417,536,413 - 17,568,193 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01419,078,678 - 19,132,212 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1419,078,680 - 19,132,208 (-)Ensemblrn6Rnor6.0
Rnor_5.01419,035,336 - 19,039,510 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01418,988,809 - 19,008,149 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41419,049,664 - 19,082,977 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1416,899,392 - 16,930,240 (-)NCBICelera
RGSC_v3.11419,049,663 - 19,082,977 (-)NCBI
Cytogenetic Map14p22NCBI
AFM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38473,481,745 - 73,504,001 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl473,481,665 - 73,504,036 (+)Ensemblhg38GRCh38
GRCh37474,347,462 - 74,369,718 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36474,566,326 - 74,588,582 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34474,712,496 - 74,734,753NCBI
Celera471,707,194 - 71,729,436 (+)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef470,158,855 - 70,181,099 (+)NCBIHuRef
CHM1_1474,383,462 - 74,405,708 (+)NCBICHM1_1
T2T-CHM13v2.0476,825,372 - 76,847,610 (+)NCBIT2T-CHM13v2.0
Afm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39590,666,808 - 90,701,403 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl590,666,791 - 90,701,402 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38590,518,949 - 90,553,544 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,518,932 - 90,553,543 (+)Ensemblmm10GRCm38
MGSCv37590,947,975 - 90,982,570 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36591,594,163 - 91,641,425 (+)NCBIMGSCv36mm8
Celera588,680,306 - 88,704,975 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
AFM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2356,559,516 - 56,583,201 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1456,748,574 - 56,771,840 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0450,691,556 - 50,714,140 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1456,523,712 - 56,545,919 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl456,519,389 - 56,545,974 (-)EnsemblpanPan2panpan1.1
AFM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11362,212,230 - 62,235,136 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1362,053,814 - 62,294,709 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1361,881,887 - 61,904,769 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01363,021,767 - 63,044,655 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1363,021,855 - 63,044,642 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11362,633,366 - 62,656,263 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01362,126,432 - 62,149,372 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01363,262,556 - 63,285,453 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
AFM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl869,706,896 - 69,728,255 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1869,706,823 - 69,728,269 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2873,806,942 - 73,828,360 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AFM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1721,950,222 - 21,972,612 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl721,950,705 - 21,972,739 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666084824,453 - 846,386 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Afm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473533,945,107 - 34,015,900 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Afm
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1113,961,481 - 3,986,611 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Afm
66 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:70
Count of miRNA genes:66
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000060535
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14395787818558812Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141133490630674469Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141133471628389666Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14117877928Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141513759431238250Rat

Markers in Region
D14Got24  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21417,565,285 - 17,565,435 (+)MAPPERmRatBN7.2
Rnor_6.01419,133,629 - 19,133,778NCBIRnor6.0
Rnor_5.01419,040,970 - 19,041,119UniSTSRnor5.0
RGSC_v3.41419,084,436 - 19,084,586RGDRGSC3.4
RGSC_v3.41419,084,437 - 19,084,586UniSTSRGSC3.4
Celera1416,931,700 - 16,931,849UniSTS
RGSC_v3.11419,084,437 - 19,084,586RGD
RH 3.4 Map14221.6RGD
RH 3.4 Map14221.6UniSTS
Cytogenetic Map14p22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
6 9 14 57 86 82 59 25 59 5 209 55 40 81 73 23 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000060535   ⟹   ENSRNOP00000057275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1417,815,194 - 17,848,039 (-)Ensembl
mRatBN7.2 Ensembl1417,531,024 - 17,563,870 (-)Ensembl
Rnor_6.0 Ensembl1419,078,680 - 19,132,208 (-)Ensembl
RefSeq Acc Id: NM_172320   ⟹   NP_758823
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81417,815,194 - 17,848,039 (-)NCBI
mRatBN7.21417,531,022 - 17,563,865 (-)NCBI
Rnor_6.01419,079,601 - 19,132,169 (-)NCBI
Rnor_5.01418,988,809 - 19,008,149 (-)NCBI
Rnor_5.01419,035,336 - 19,039,510 (-)NCBI
RGSC_v3.41419,049,664 - 19,082,977 (-)RGD
Celera1416,899,392 - 16,930,240 (-)RGD
Sequence:
RefSeq Acc Id: XM_039091644   ⟹   XP_038947572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81417,815,210 - 17,848,042 (-)NCBI
mRatBN7.21417,531,034 - 17,563,868 (-)NCBI
RefSeq Acc Id: NP_758823   ⟸   NM_172320
- Peptide Label: precursor
- UniProtKB: P36953 (UniProtKB/Swiss-Prot),   G3V9R9 (UniProtKB/TrEMBL),   A6KKF6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057275   ⟸   ENSRNOT00000060535
RefSeq Acc Id: XP_038947572   ⟸   XM_039091644
- Peptide Label: isoform X1
Protein Domains
Albumin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P36953-F1-model_v2 AlphaFold P36953 1-608 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699232
Promoter ID:EPDNEW_R9757
Type:single initiation site
Name:Afm_1
Description:afamin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01419,132,205 - 19,132,265EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628614 AgrOrtholog
BioCyc Gene G2FUF-16188 BioCyc
Ensembl Genes ENSRNOG00000002878 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000060535 ENTREZGENE
Gene3D-CATH 1.10.246.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7322187 IMAGE-MGC_LOAD
InterPro ALB/AFP/VDB UniProtKB/Swiss-Prot
  Serum_albumin-like UniProtKB/Swiss-Prot
  Serum_albumin/AFP/Afamin UniProtKB/Swiss-Prot
  Serum_albumin_CS UniProtKB/Swiss-Prot
  Serum_albumin_N UniProtKB/Swiss-Prot
KEGG Report rno:282708 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109482 IMAGE-MGC_LOAD
NCBI Gene 282708 ENTREZGENE
PANTHER AFAMIN UniProtKB/Swiss-Prot
  PTHR11385 UniProtKB/Swiss-Prot
Pfam Serum_albumin UniProtKB/Swiss-Prot
PhenoGen Afm PhenoGen
PIRSF Serum_albumin_subgroup UniProtKB/Swiss-Prot
PRINTS SERUMALBUMIN UniProtKB/Swiss-Prot
PROSITE ALBUMIN_1 UniProtKB/Swiss-Prot
  ALBUMIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002878 RatGTEx
SMART ALBUMIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48552 UniProtKB/Swiss-Prot
UniProt A6KKF2_RAT UniProtKB/TrEMBL
  A6KKF3_RAT UniProtKB/TrEMBL
  A6KKF4_RAT UniProtKB/TrEMBL
  A6KKF6 ENTREZGENE, UniProtKB/TrEMBL
  A6KKF7_RAT UniProtKB/TrEMBL
  AFAM_RAT UniProtKB/Swiss-Prot
  G3V9R9 ENTREZGENE, UniProtKB/TrEMBL
  P36953 ENTREZGENE
  Q5BJP7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Afm  afamin      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Afm  afamin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expression is decreased 2.5 fold in SHR rats compared to WKY rats 1357414
gene_process possible role in the transport of yet unknown ligand 724707