Pip4k2a (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha) - Rat Genome Database

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Gene: Pip4k2a (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha) Rattus norvegicus
Analyze
Symbol: Pip4k2a (Ensembl: AABR07028769.1)
Name: phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
RGD ID: 621708
Description: Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; and protein homodimerization activity. Predicted to be involved in several processes, including 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; autophagosome-lysosome fusion; and megakaryocyte development. Predicted to be located in autophagosome; cytosol; and lysosome. Predicted to be active in plasma membrane. Orthologous to human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha); PARTICIPATES IN phosphoinositide metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; 1-phosphatidylinositol-5-phosphate 4-kinase 2-alpha; 1-phosphatidylinositol-5-phosphate 4-kinase A; diphosphoinositide kinase 2-alpha; LOC100363127; LOC100909950; phosphatidylinositol 5-phosphate 4-kinase type II alpha; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like; phosphatidylinositol-4-phosphate 5-kinase, type II, alpha; phosphatidylinositol-5-phosphate 4-kinase type-2 alpha; phosphatidylinositol-5-phosphate 4-kinase type-2 alpha-like; phosphatidylinositol-5-phosphate 4-kinase, type II, alpha; PI(5)P 4-kinase type II alpha; PIP4KII-alpha; Pip5k2a; PIPK2 alpha; ptdIns(5)P-4-kinase isoform 2-alpha; uncharacterized LOC100909950
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81786,405,080 - 86,576,597 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1786,405,081 - 86,576,430 (-)EnsemblGRCr8
mRatBN7.21781,496,669 - 81,668,180 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1781,496,670 - 81,668,029 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1784,970,346 - 85,134,961 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01788,805,740 - 88,970,367 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01782,822,473 - 82,987,105 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01785,533,056 - 85,748,843 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01787,260,013 - 87,284,895 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01787,360,739 - 87,463,987 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41792,950,531 - 93,111,944 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1780,777,213 - 80,940,203 (-)NCBICelera
RGSC_v3.11792,963,045 - 93,122,777NCBI
Cytogenetic Map17q12.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
melanoma  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
butan-1-ol  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
carbonyl sulfide  (EXP)
chlorpyrifos  (EXP)
choline  (ISO)
clobetasol  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
Dibutyl phosphate  (ISO)
diethylstilbestrol  (ISO)
dimethyl sulfoxide  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
isoflurane  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
nickel atom  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
parathion  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
rifampicin  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
testosterone  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
autophagosome  (IEA,ISO)
cytoplasm  (IEA)
cytosol  (IEA,ISO)
lysosome  (IEA,ISO,ISS)
nucleus  (IEA)
photoreceptor inner segment  (IEA)
photoreceptor outer segment  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. Ishihara H, etal., J Biol Chem 1998 Apr 10;273(15):8741-8.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:16434494   PMID:22206666   PMID:23758345   PMID:25495341   PMID:25578879  


Genomics

Comparative Map Data
Pip4k2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81786,405,080 - 86,576,597 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1786,405,081 - 86,576,430 (-)EnsemblGRCr8
mRatBN7.21781,496,669 - 81,668,180 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1781,496,670 - 81,668,029 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1784,970,346 - 85,134,961 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01788,805,740 - 88,970,367 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01782,822,473 - 82,987,105 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01785,533,056 - 85,748,843 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01787,260,013 - 87,284,895 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01787,360,739 - 87,463,987 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41792,950,531 - 93,111,944 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1780,777,213 - 80,940,203 (-)NCBICelera
RGSC_v3.11792,963,045 - 93,122,777NCBI
Cytogenetic Map17q12.3NCBI
PIP4K2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381022,534,854 - 22,714,578 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1022,534,854 - 22,714,578 (-)Ensemblhg38GRCh38
GRCh371022,823,783 - 23,003,507 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361022,863,772 - 23,043,509 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341022,865,828 - 23,043,490NCBI
Celera1022,511,468 - 22,691,158 (-)NCBICelera
Cytogenetic Map10p12.2NCBI
HuRef1022,484,658 - 22,664,398 (-)NCBIHuRef
CHM1_11022,824,227 - 23,003,964 (-)NCBICHM1_1
T2T-CHM13v2.01022,553,890 - 22,733,579 (-)NCBIT2T-CHM13v2.0
Pip4k2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39218,847,066 - 19,003,101 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl218,847,066 - 19,002,937 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38218,842,255 - 18,998,291 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl218,842,255 - 18,998,126 (-)Ensemblmm10GRCm38
MGSCv37218,763,883 - 18,919,748 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36218,760,014 - 18,915,870 (-)NCBIMGSCv36mm8
Celera218,734,163 - 18,892,750 (-)NCBICelera
Cytogenetic Map2A3NCBI
Pip4k2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554296,336,355 - 6,399,672 (+)Ensembl
ChiLan1.0NW_0049554296,231,135 - 6,399,672 (+)NCBIChiLan1.0ChiLan1.0
PIP4K2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2835,214,901 - 35,394,214 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11035,220,226 - 35,399,538 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01022,691,355 - 22,870,628 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11023,066,771 - 23,141,230 (-)NCBIPanPan1.1PanPan1.1panPan2
PIP4K2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1210,464,019 - 10,642,365 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl210,463,010 - 10,640,327 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha29,157,521 - 9,335,592 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.028,663,138 - 8,841,553 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl28,663,029 - 8,840,895 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.128,027,620 - 8,205,381 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028,110,958 - 8,289,331 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028,279,324 - 8,457,701 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pip4k2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934422,420,301 - 22,576,740 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365205,383,737 - 5,540,203 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365205,383,737 - 5,540,176 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIP4K2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1052,224,389 - 52,408,922 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11052,224,367 - 52,408,928 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21057,880,198 - 58,064,685 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIP4K2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1922,306,307 - 22,482,074 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl922,306,312 - 22,481,954 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605128,057,994 - 28,238,500 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pip4k2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247965,962,999 - 6,113,087 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247965,963,005 - 6,113,081 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pip4k2a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1145,028,683 - 5,193,306 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pip4k2a
797 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:715
Count of miRNA genes:305
Interacting mature miRNAs:395
Transcripts:ENSRNOT00000022375
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat

Markers in Region
RH143686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,497,324 - 81,497,425 (+)MAPPERmRatBN7.2
Rnor_6.01785,533,712 - 85,533,812NCBIRnor6.0
Rnor_5.01787,260,669 - 87,260,769UniSTSRnor5.0
RGSC_v3.41792,951,187 - 92,951,287UniSTSRGSC3.4
Celera1780,777,869 - 80,777,969UniSTS
RH 3.4 Map17831.5UniSTS
Cytogenetic Map17q12.3UniSTS
RH142512  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,605,835 - 81,605,978 (+)MAPPERmRatBN7.2
Rnor_6.01786,695,393 - 86,695,535NCBIRnor6.0
Rnor_6.01785,686,686 - 85,686,828NCBIRnor6.0
Rnor_5.01788,400,558 - 88,400,700UniSTSRnor5.0
Rnor_5.01787,402,059 - 87,402,201UniSTSRnor5.0
RGSC_v3.41793,049,180 - 93,049,322UniSTSRGSC3.4
Celera1780,878,300 - 80,878,442UniSTS
RH 3.4 Map17812.5UniSTS
Cytogenetic Map17q12.3UniSTS
RH139055  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,498,774 - 81,498,904 (+)MAPPERmRatBN7.2
Rnor_6.01785,535,162 - 85,535,291NCBIRnor6.0
Rnor_5.01787,262,119 - 87,262,248UniSTSRnor5.0
RGSC_v3.41792,952,637 - 92,952,766UniSTSRGSC3.4
Celera1780,779,319 - 80,779,448UniSTS
RH 3.4 Map17834.5UniSTS
Cytogenetic Map17q12.3UniSTS
AI577465  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,496,740 - 81,496,842 (+)MAPPERmRatBN7.2
Rnor_6.01785,533,128 - 85,533,229NCBIRnor6.0
Rnor_5.01787,260,085 - 87,260,186UniSTSRnor5.0
RGSC_v3.41792,950,603 - 92,950,704UniSTSRGSC3.4
Celera1780,777,285 - 80,777,386UniSTS
RH 3.4 Map17831.4UniSTS
Cytogenetic Map17q12.3UniSTS
BE118396  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,499,475 - 81,499,636 (+)MAPPERmRatBN7.2
Rnor_6.01785,535,861 - 85,536,021NCBIRnor6.0
Rnor_5.01787,262,818 - 87,262,978UniSTSRnor5.0
RGSC_v3.41792,953,336 - 92,953,496UniSTSRGSC3.4
Celera1780,780,018 - 80,780,178UniSTS
RH 3.4 Map17833.5UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 52 67 138 95 11 51 36 32 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000022375   ⟹   ENSRNOP00000022375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1786,405,081 - 86,576,430 (-)Ensembl
mRatBN7.2 Ensembl1781,496,670 - 81,668,029 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156539   ⟹   ENSRNOP00000107584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1786,405,081 - 86,569,559 (-)Ensembl
RefSeq Acc Id: NM_053926   ⟹   NP_446378
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,405,080 - 86,576,430 (-)NCBI
mRatBN7.21781,496,669 - 81,668,029 (-)NCBI
Rnor_6.01785,533,056 - 85,748,843 (-)NCBI
Rnor_5.01787,260,013 - 87,284,895 (-)NCBI
Rnor_5.01787,360,739 - 87,463,987 (-)NCBI
RGSC_v3.41792,950,531 - 93,111,944 (-)RGD
Celera1780,777,213 - 80,940,203 (-)RGD
Sequence:
RefSeq Acc Id: XM_039095304   ⟹   XP_038951232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,408,921 - 86,576,597 (-)NCBI
mRatBN7.21781,496,669 - 81,668,180 (-)NCBI
RefSeq Acc Id: XM_039095305   ⟹   XP_038951233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,405,080 - 86,459,418 (-)NCBI
mRatBN7.21781,496,669 - 81,551,005 (-)NCBI
RefSeq Acc Id: XM_039095306   ⟹   XP_038951234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,405,080 - 86,576,597 (-)NCBI
mRatBN7.21781,496,669 - 81,668,179 (-)NCBI
RefSeq Acc Id: NP_446378   ⟸   NM_053926
- UniProtKB: Q9R0I8 (UniProtKB/Swiss-Prot),   A6JM97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038951232   ⟸   XM_039095304
- Peptide Label: isoform X1
- UniProtKB: A6JM97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951234   ⟸   XM_039095306
- Peptide Label: isoform X3
- UniProtKB: A6JM97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951233   ⟸   XM_039095305
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000022375   ⟸   ENSRNOT00000022375
Ensembl Acc Id: ENSRNOP00000107584   ⟸   ENSRNOT00000156539
Protein Domains
PIPK

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LX22-F1-model_v2 AlphaFold F1LX22 1-194 view protein structure
AF-Q9R0I8-F1-model_v2 AlphaFold Q9R0I8 1-406 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621708 AgrOrtholog
BioCyc Gene G2FUF-8548 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6367 [D-myo-inositol-5-phosphate metabolism] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6367 BioCyc
Ensembl Genes ENSRNOG00000016670 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022375 ENTREZGENE
  ENSRNOT00000022375.8 UniProtKB/Swiss-Prot
Gene3D-CATH 2-Layer Sandwich UniProtKB/Swiss-Prot
  3.30.800.10 UniProtKB/Swiss-Prot
InterPro PInositol-4-P-4/5-kinase_C_sf UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase_core UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase_N UniProtKB/Swiss-Prot
KEGG Report rno:116723 UniProtKB/Swiss-Prot
NCBI Gene 116723 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA UniProtKB/Swiss-Prot
  PTHR23086 UniProtKB/Swiss-Prot
Pfam PIP5K UniProtKB/Swiss-Prot
PhenoGen Pip4k2a PhenoGen
PROSITE PIPK UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016670 RatGTEx
SMART PIPKc UniProtKB/Swiss-Prot
Superfamily-SCOP SAICAR synthase-like UniProtKB/Swiss-Prot
UniProt A0ABK0LPB1_RAT UniProtKB/TrEMBL
  A6JM97 ENTREZGENE, UniProtKB/TrEMBL
  F1LX22_RAT UniProtKB/TrEMBL
  PI42A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase type 2 alpha  LOC100909950  uncharacterized LOC100909950  Data merged from RGD:6501048 737654 PROVISIONAL
2016-04-20 Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase type 2 alpha  Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase, type II, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase, type II, alpha  LOC100363127  phosphatidylinositol-5-phosphate 4-kinase type-2 alpha-like  Data merged from RGD:2324762 737654 PROVISIONAL
2012-07-05 LOC100909950  uncharacterized LOC100909950      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-12 LOC100363127  phosphatidylinositol-5-phosphate 4-kinase type-2 alpha-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-25 Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase, type II, alpha  Pip5k2a  phosphatidylinositol-4-phosphate 5-kinase, type II, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Pip5k2a  phosphatidylinositol-4-phosphate 5-kinase, type II, alpha      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Pip5k2a  phosphatidylinositol-4-phosphate 5-kinase, type II, alpha      Symbol and Name status set to provisional 70820 PROVISIONAL