PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase, type II, alpha)

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Keyword

Gene: PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase, type II, alpha) Homo sapiens

Symbol:

PIP4K2A

Name:

phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

Description:

Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-4-phosphate-5-kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-alpha; diphosphoinositide kinase 2-alpha; FLJ13267; OTTHUMP00000019300; phosphatidylinositol 5-phosphate 4-kinase type II alpha; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; phosphatidylinositol-4-phosphate 5-kinase, type II, alpha; phosphatidylinositol-5-phosphate 4-kinase type-2 alpha; PI(5)P 4-kinase type II alpha; PI5P4KA; PIP4KII-alpha; PIP5K2A; PIP5KII-alpha; PIP5KIIA; PIP5KIIalpha; PIP5KIII; PIPK; PtdIns(4)P-5-kinase B isoform; ptdIns(4)P-5-kinase C isoform; ptdIns(5)P-4-kinase isoform 2-alpha; type II phosphatidylinositol-4-phosphate 5-kinase 53 K isoform

Orthologs:

Mus musculus : Pip4k2a (phosphatidylinositol-5-phosphate 4-kinase, type II, alpha) MGI
Rattus norvegicus : Pip4k2a (phosphatidylinositol-5-phosphate 4-kinase, type II, alpha)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	10	22,734,600 - 22,914,127	-	NCBI
Human Genome Assembly HuRef	10	22,484,658 - 22,664,398	-	NCBI
Human Genome Assembly GRCh37	10	22,823,766 - 23,003,503	-	NCBI
Human Genome Assembly Build 36	10	22,863,772 - 23,043,509	-	NCBI
Human Cytogenetic Map	10	p12.2		NCBI
Human Genome Assembly	10	22,865,828 - 23,043,490		NCBI