Nat8 (N-acetyltransferase 8) - Rat Genome Database

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Pathways
Gene: Nat8 (N-acetyltransferase 8) Rattus norvegicus
Analyze
Symbol: Nat8
Name: N-acetyltransferase 8
RGD ID: 621609
Description: Predicted to enable L-cysteine-S-conjugate N-acetyltransferase activity and protein-lysine-acetyltransferase activity. Predicted to be involved in gastrulation with mouth forming second; peptidyl-lysine N6-acetylation; and positive regulation of gene expression. Predicted to be located in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment membrane. Orthologous to human NAT8 (N-acetyltransferase 8 (putative)); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acetyltransferase 2; ATase2; camello-like 4; camello-like protein 4; CCNAT; Cml4; cysteinyl-conjugate N-acetyltransferase; N-acetyltransferase 8 (camello like); probable N-acetyltransferase CML4; protein-lysine N6-acetyltransferase 8; putative N-acetyltransferase Camello 4
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Nat8em4Mcwi
Genetic Models: SS-Nat8em4Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84119,836,986 - 119,837,764 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4119,835,645 - 119,843,159 (-)EnsemblGRCr8
mRatBN7.24118,279,521 - 118,284,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4118,270,954 - 118,281,763 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4123,760,745 - 123,761,523 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04119,535,547 - 119,536,325 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04118,149,119 - 118,149,897 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04117,525,963 - 117,527,443 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04182,101,688 - 182,103,119 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44120,001,277 - 120,002,055 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4107,259,757 - 107,260,535 (-)NCBICelera
RGSC_v3.14120,245,757 - 120,246,536 (-)NCBI
Cytogenetic Map4q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4,5,3',4',5'-Hexachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
amphotericin B  (ISO)
arecoline  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorohydrocarbon  (EXP)
choline  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
dichloroacetic acid  (ISO)
diethyl maleate  (EXP)
epoxiconazole  (ISO)
folic acid  (ISO)
furan  (EXP)
indole-3-methanol  (EXP)
L-ethionine  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
methylmercury chloride  (EXP)
N-Acetyl-S-(1,2-dichlorovinyl)-cysteine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
ochratoxin A  (EXP)
okadaic acid  (ISO)
omeprazole  (EXP)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (EXP)
sodium arsenite  (ISO)
streptozocin  (EXP)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
trichloroethene  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis. Popsueva AE, etal., Dev Biol 2001 Jun 15;234(2):483-96.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:19011241   PMID:20392701   PMID:23376485   PMID:24556617  


Genomics

Comparative Map Data
Nat8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84119,836,986 - 119,837,764 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4119,835,645 - 119,843,159 (-)EnsemblGRCr8
mRatBN7.24118,279,521 - 118,284,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4118,270,954 - 118,281,763 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4123,760,745 - 123,761,523 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04119,535,547 - 119,536,325 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04118,149,119 - 118,149,897 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04117,525,963 - 117,527,443 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04182,101,688 - 182,103,119 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44120,001,277 - 120,002,055 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4107,259,757 - 107,260,535 (-)NCBICelera
RGSC_v3.14120,245,757 - 120,246,536 (-)NCBI
Cytogenetic Map4q34NCBI
NAT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38273,640,723 - 73,642,422 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl273,640,723 - 73,643,229 (-)Ensemblhg38GRCh38
GRCh37273,867,850 - 73,869,549 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,721,358 - 73,723,045 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34273,779,613 - 73,781,182NCBI
Celera273,718,675 - 73,720,362 (-)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef273,602,763 - 73,604,450 (-)NCBIHuRef
CHM1_1273,798,615 - 73,800,302 (-)NCBICHM1_1
T2T-CHM13v2.0273,653,777 - 73,655,476 (-)NCBIT2T-CHM13v2.0
Nat8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,807,369 - 85,813,839 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl685,807,370 - 85,809,064 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38685,830,387 - 85,836,857 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,830,388 - 85,832,082 (-)Ensemblmm10GRCm38
MGSCv37685,780,381 - 85,781,884 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36685,796,045 - 85,797,740 (-)NCBIMGSCv36mm8
Celera687,767,874 - 87,769,374 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.49NCBI
NAT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21252,730,365 - 52,731,508 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A52,733,118 - 52,734,681 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A73,702,173 - 73,703,763 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A75,189,613 - 75,191,198 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A75,189,726 - 75,190,409 (-)EnsemblpanPan2panpan1.1
NAT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,285,915 - 49,288,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,929,557 - 48,932,108 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01750,148,044 - 50,150,636 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11749,164,172 - 49,166,764 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01749,231,560 - 49,234,152 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,790,606 - 49,793,199 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
NAT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,250,665 - 69,254,785 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1369,250,326 - 69,254,079 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,452,154 - 72,453,708 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NAT8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,550,087 - 33,552,301 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1433,551,510 - 33,552,193 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604578,547,713 - 78,549,293 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nat8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476296,735 - 97,440 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Nat8
8 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)496731383141731383Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)492406430137406430Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)486058928131411333Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)488883695133883695Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486583980131583980Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)488883695133883695Rat


Genetic Models
This gene Nat8 is modified in the following models/strains:


Expression

RNA-SEQ Expression

appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
1 11 38 4 55 19 5 37 36 9 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000021243   ⟹   ENSRNOP00000021243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4119,835,645 - 119,843,159 (-)Ensembl
mRatBN7.2 Ensembl4118,279,520 - 118,281,763 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097720   ⟹   ENSRNOP00000080047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4118,270,954 - 118,281,156 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099459   ⟹   ENSRNOP00000080565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4118,270,954 - 118,281,156 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102192   ⟹   ENSRNOP00000083742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4118,271,113 - 118,281,156 (-)Ensembl
RefSeq Acc Id: NM_022635   ⟹   NP_072157
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84119,836,986 - 119,837,764 (-)NCBI
mRatBN7.24118,279,521 - 118,280,299 (-)NCBI
Rnor_6.04117,525,963 - 117,526,741 (-)NCBI
Rnor_5.04182,101,688 - 182,103,119 (-)NCBI
RGSC_v3.44120,001,277 - 120,002,055 (-)RGD
Celera4107,259,757 - 107,260,535 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_072157 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF22298 (Get FASTA)   NCBI Sequence Viewer  
  EDL91203 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021243
  ENSRNOP00000021243.3
  ENSRNOP00000080047.1
  ENSRNOP00000080565.1
  ENSRNOP00000083742.1
GenBank Protein Q9QXT3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_072157   ⟸   NM_022635
- UniProtKB: Q9QXT3 (UniProtKB/Swiss-Prot),   A6IAT5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000080047   ⟸   ENSRNOT00000097720
Ensembl Acc Id: ENSRNOP00000080565   ⟸   ENSRNOT00000099459
Ensembl Acc Id: ENSRNOP00000021243   ⟸   ENSRNOT00000021243
Ensembl Acc Id: ENSRNOP00000083742   ⟸   ENSRNOT00000102192
Protein Domains
N-acetyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QXT3-F1-model_v2 AlphaFold Q9QXT3 1-222 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621609 AgrOrtholog
BioCyc Gene G2FUF-43928 BioCyc
Ensembl Genes ENSRNOG00000063398 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000078949 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000021243 ENTREZGENE
  ENSRNOT00000021243.6 UniProtKB/Swiss-Prot
  ENSRNOT00000097720.1 UniProtKB/Swiss-Prot
  ENSRNOT00000099459.1 UniProtKB/Swiss-Prot
  ENSRNOT00000102192.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.630.30 UniProtKB/Swiss-Prot
InterPro Acyl_CoA_acyltransferase UniProtKB/Swiss-Prot
  Camello_NAT UniProtKB/Swiss-Prot
  GNAT_dom UniProtKB/Swiss-Prot
KEGG Report rno:64570 UniProtKB/Swiss-Prot
NCBI Gene 64570 ENTREZGENE
PANTHER GNAT FAMILY N-ACETYLTRANSFERASE UniProtKB/Swiss-Prot
  N-ACETYLTRANSFERASE 8-RELATED UniProtKB/Swiss-Prot
Pfam Acetyltransf_1 UniProtKB/Swiss-Prot
PhenoGen Nat8 PhenoGen
PROSITE GNAT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000063398 RatGTEx
  ENSRNOG00000078949 RatGTEx
Superfamily-SCOP SSF55729 UniProtKB/Swiss-Prot
UniProt A6IAT5 ENTREZGENE
  NAT8_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A6IAT5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-11-05 Nat8  N-acetyltransferase 8  Cml4  camello-like 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-03-29 Cml4  camello-like 4  Nat8  N-acetyltransferase 8 (camello like)  Symbol and Name updated 1299863 APPROVED
2004-09-10 Nat8  N-acetyltransferase 8 (camello like)  Cml4  putative N-acetyltransferase Camello 4  Symbol and Name updated 1299863 APPROVED
2002-08-07 Cml4  putative N-acetyltransferase Camello 4      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology has similarity to Xenopus laevis camello (Xcml) 632468
gene_product member of the camello protein family 632468