NAT8 (N-acetyltransferase 8 (putative)) - Rat Genome Database

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Gene: NAT8 (N-acetyltransferase 8 (putative)) Chlorocebus sabaeus
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Symbol: NAT8
Name: N-acetyltransferase 8 (putative)
RGD ID: 18346022
Description: ENCODES a protein that exhibits cysteine-S-conjugate N-acetyltransferase activity (ortholog); lysine N-acetyltransferase activity, acting on acetyl phosphate as donor (ortholog); INVOLVED IN gastrulation with mouth forming second (ortholog); positive regulation of gene expression (ortholog); ASSOCIATED WITH congenital disorder of glycosylation type IIb (ortholog); dystonia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); endoplasmic reticulum-Golgi intermediate compartment (ortholog); endoplasmic reticulum-Golgi intermediate compartment membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103220050; N-acetyltransferase 8; probable N-acetyltransferase 8
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,550,087 - 33,552,301 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604578,547,713 - 78,549,293 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NAT8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,550,087 - 33,552,301 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604578,547,713 - 78,549,293 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NAT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38273,640,723 - 73,642,422 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl273,640,723 - 73,642,422 (-)EnsemblGRCh38hg38GRCh38
GRCh37273,867,850 - 73,869,549 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,721,358 - 73,723,045 (-)NCBINCBI36Build 36hg18NCBI36
Build 34273,779,613 - 73,781,182NCBI
Celera273,718,675 - 73,720,362 (-)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef273,602,763 - 73,604,450 (-)NCBIHuRef
CHM1_1273,798,615 - 73,800,302 (-)NCBICHM1_1
T2T-CHM13v2.0273,653,777 - 73,655,476 (-)NCBIT2T-CHM13v2.0
Nat8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,807,369 - 85,813,839 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl685,807,370 - 85,809,064 (-)EnsemblGRCm39 Ensembl
GRCm38685,830,387 - 85,836,857 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,830,388 - 85,832,082 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,780,381 - 85,781,884 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36685,796,045 - 85,797,740 (-)NCBIMGSCv36mm8
Celera687,767,874 - 87,769,374 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.49NCBI
Nat8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84119,836,986 - 119,837,764 (-)NCBIGRCr8
mRatBN7.24118,279,521 - 118,284,671 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4118,270,954 - 118,281,763 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4123,760,745 - 123,761,523 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04119,535,547 - 119,536,325 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04118,149,119 - 118,149,897 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04117,525,963 - 117,527,443 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04182,101,688 - 182,103,119 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,001,277 - 120,002,055 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14120,245,757 - 120,246,536 (-)NCBI
Celera4107,259,757 - 107,260,535 (-)NCBICelera
Cytogenetic Map4q34NCBI
NAT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21252,730,365 - 52,731,508 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A52,733,118 - 52,734,681 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A73,702,173 - 73,703,763 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A75,189,613 - 75,191,198 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A75,189,726 - 75,190,409 (-)Ensemblpanpan1.1panPan2
NAT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,285,915 - 49,288,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,929,557 - 48,932,108 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01750,148,044 - 50,150,636 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11749,164,172 - 49,166,764 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01749,231,560 - 49,234,152 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,790,606 - 49,793,199 (+)NCBIUU_Cfam_GSD_1.0
NAT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1369,250,326 - 69,254,079 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,452,154 - 72,453,708 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Nat8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476296,735 - 97,440 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 21 11 59
Below cutoff 15 6 1

Sequence


RefSeq Acc Id: XM_007970208   ⟹   XP_007968399
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11433,550,087 - 33,552,301 (+)NCBI
Vero_WHO_p1.0NW_02366604578,547,713 - 78,549,293 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007968399 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018947
  ENSCSAP00000018947.1
RefSeq Acc Id: XP_007968399   ⟸   XM_007970208
- UniProtKB: A0A0D9SDK8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019439 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019529.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.630.30 UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/TrEMBL
  GNAT_dom UniProtKB/TrEMBL
KEGG Report csab:103220050 UniProtKB/TrEMBL
NCBI Gene LOC103220050 ENTREZGENE
PANTHER GNAT FAMILY N-ACETYLTRANSFERASE UniProtKB/TrEMBL
  N-ACETYLTRANSFERASE 8-RELATED UniProtKB/TrEMBL
Pfam Acetyltransf_1 UniProtKB/TrEMBL
PROSITE GNAT UniProtKB/TrEMBL
Superfamily-SCOP SSF55729 UniProtKB/TrEMBL
UniProt A0A0D9SDK8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 NAT8  N-acetyltransferase 8 (putative)  LOC103220050  probable N-acetyltransferase 8  Symbol and/or name change 5135510 APPROVED