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Gene: Adarb2 (adenosine deaminase RNA specific B2) Rattus norvegicus

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Symbol:

Adarb2

Name:

adenosine deaminase RNA specific B2

RGD ID:

621519

Description:

Predicted to enable RNA binding activity and deaminase activity. Predicted to be involved in 3'-UTR-mediated mRNA stabilization; RNA processing; and adenosine to inosine editing. Predicted to be active in cytoplasm and nucleolus. Orthologous to human ADARB2 (adenosine deaminase RNA specific B2 (inactive)); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Adar3; adenosine deaminase 3, RNA dependent; adenosine deaminase, RNA-specific, B2; double-stranded RNA-specific editase B2; dsRNA adenosine deaminase B2; Red2; RNA-dependent adenosine deaminase 3; RNA-editing deaminase 2; RNA-editing enzyme 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADARB2 (adenosine deaminase RNA specific B2 (inactive))	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Adarb2 (adenosine deaminase, RNA-specific, B2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Adarb2 (adenosine deaminase RNA specific B2 (inactive))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADARB2 (adenosine deaminase RNA specific B2 (inactive))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ADARB2 (adenosine deaminase RNA specific B2 (inactive))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Adarb2 (adenosine deaminase RNA specific B2 (inactive))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ADARB2 (adenosine deaminase RNA specific B2 (inactive))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ADARB2 (adenosine deaminase RNA specific B2 (inactive))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Adarb2 (adenosine deaminase RNA specific B2 (inactive))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Adarb2 (adenosine deaminase RNA specific B2 (inactive))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Adarb2 (adenosine deaminase, RNA-specific, B2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ADARB2 (adenosine deaminase RNA specific B2 (inactive))	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	adarb2 (adenosine deaminase RNA specific B2 (inactive))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	adr-2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Adar	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Adar	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	adarb2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	adarb2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	66,660,586 - 67,211,104 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	66,665,506 - 67,210,749 (-)	Ensembl				GRCr8
mRatBN7.2	17	61,750,437 - 62,300,984 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	61,756,067 - 62,300,831 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	65,276,950 - 65,815,159 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	69,105,757 - 69,643,931 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	63,127,154 - 63,665,371 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	58,098,979 - 58,653,137 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	58,104,559 - 58,301,260 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	59,899,851 - 60,449,163 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	72,680,982 - 73,238,156 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	54,538,865 - 55,080,965 (-)	NCBI		Celera
RGSC_v3.1	17	72,691,814 - 73,248,989 (-)	NCBI
Cytogenetic Map	17	q12.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Parkinson's disease (ISO)

substance-related disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

coumarin (ISO)

Cuprizon (EXP)

dioxygen (ISO)

fenamidone (ISO)

flavonoids (EXP)

fulvestrant (ISO)

genistein (ISO)

hydroquinone (ISO)

iron dichloride (ISO)

methapyrilene (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-acetyl-1,4-benzoquinone imine (ISO)

Nor-9-carboxy-delta9-THC (ISO)

O-methyleugenol (ISO)

paracetamol (ISO)

serpentine asbestos (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

toluene (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

3'-UTR-mediated mRNA stabilization (IEA,ISO,ISS)

adenosine to inosine editing (IBA,IEA)

mRNA metabolic process (IEA)

mRNA processing (IEA)

negative regulation of mRNA modification (IEA,ISO)

RNA processing (IBA,IEA)

Cellular Component

cytoplasm (IBA)

nucleolus (IBA)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO,ISS)

Molecular Function

adenosine deaminase activity (IEA)

deaminase activity (IEA)

double-stranded RNA adenosine deaminase activity (IDA,ISO,ISS)

double-stranded RNA binding (IBA)

metal ion binding (IEA)

mRNA binding (IEA,ISO,ISS)

RNA binding (IEA)

RNA sequestering activity (IEA,ISO)

tRNA-specific adenosine deaminase activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	RED2, a brain-specific member of the RNA-specific adenosine deaminase family.	Melcher T, etal., J Biol Chem 1996 Dec 13;271(50):31795-8.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22658674

Genomics

Comparative Map Data

Adarb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	66,660,586 - 67,211,104 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	66,665,506 - 67,210,749 (-)	Ensembl				GRCr8
mRatBN7.2	17	61,750,437 - 62,300,984 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	61,756,067 - 62,300,831 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	65,276,950 - 65,815,159 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	69,105,757 - 69,643,931 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	63,127,154 - 63,665,371 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	58,098,979 - 58,653,137 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	58,104,559 - 58,301,260 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	59,899,851 - 60,449,163 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	72,680,982 - 73,238,156 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	54,538,865 - 55,080,965 (-)	NCBI		Celera
RGSC_v3.1	17	72,691,814 - 73,248,989 (-)	NCBI
Cytogenetic Map	17	q12.1	NCBI

ADARB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	1,177,313 - 1,737,525 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	1,177,313 - 1,737,525 (-)	Ensembl			hg38	GRCh38
GRCh37	10	1,223,253 - 1,779,719 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	1,218,073 - 1,769,670 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	1,218,072 - 1,769,670	NCBI
Celera	10	1,177,236 - 1,724,446 (-)	NCBI		Celera
Cytogenetic Map	10	p15.3	NCBI
HuRef	10	1,161,831 - 1,714,807 (-)	NCBI		HuRef
CHM1_1	10	1,223,357 - 1,778,901 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	1,174,042 - 1,734,916 (-)	NCBI		T2T-CHM13v2.0

Adarb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	8,252,475 - 8,818,798 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	8,252,902 - 8,818,783 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	8,202,526 - 8,768,762 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	8,202,866 - 8,768,747 (+)	Ensembl			mm10	GRCm38
MGSCv37	13	8,202,155 - 8,759,554 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	8,202,174 - 8,758,251 (+)	NCBI		MGSCv36	mm8
Celera	13	8,141,995 - 8,704,669 (+)	NCBI		Celera
Cytogenetic Map	13	A1	NCBI
cM Map	13	3.48	NCBI

Adarb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955421	29,830,905 - 30,022,685 (+)	Ensembl
ChiLan1.0	NW_004955421	29,705,289 - 30,028,013 (+)	NCBI	ChiLan1.0	ChiLan1.0

ADARB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	13,710,717 - 14,279,208 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	13,716,029 - 14,284,531 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	1,219,560 - 1,786,418 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	1,266,559 - 1,805,825 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	1,268,327 - 1,449,173 (-)	Ensembl			panPan2	panpan1.1

ADARB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	33,510,081 - 33,848,968 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	33,510,961 - 33,847,412 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	30,547,773 - 30,882,564 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	33,898,956 - 34,231,649 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	34,142,371 - 34,233,124 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	30,980,140 - 31,314,975 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	31,821,371 - 32,155,620 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	32,567,978 - 32,901,861 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Adarb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	36,235,715 - 36,715,864 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936484	12,401,502 - 12,875,689 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936484	12,400,903 - 12,876,572 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADARB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	68,013,449 - 68,467,189 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	10	68,013,531 - 68,468,583 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	75,135,379 - 75,302,238 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADARB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	1,136,461 - 1,644,196 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	1,137,037 - 1,301,657 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666051	6,194,489 - 6,714,274 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adarb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624775	9,090,545 - 9,643,355 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624775	9,089,839 - 9,646,985 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Adarb2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	14	21,928,700 - 22,471,509 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Adarb2
4718 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	24
Count of miRNA genes:	24
Interacting mature miRNAs:	24
Transcripts:	ENSRNOT00000047512
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70210	Cm15	Cardiac mass QTL 15	6.5		heart right ventricle mass (VT:0007033)	heart right ventricle wet weight (CMO:0000072)	17	30066472	75066472	Rat
152023626	Bp403	Blood pressure QTL 403	3.86		arterial blood pressure trait (VT:2000000)		17	24136127	84432719	Rat
2301412	Kidm40	Kidney mass QTL 40		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	42388164	87388164	Rat
1354588	Bvd4	Brain ventricular dilatation QTL 4	5.31	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	58194064	87388164	Rat
9590107	Sffal7	Serum free fatty acids level QTL 7	4.81	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	17	33104645	78104645	Rat
1354654	Spl7	Serum phospholipid level QTL 7	5.5		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	17	38031354	83031354	Rat
2317038	Ginf3	Gastrointestinal inflammation QTL 3	2.89	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	17	54829503	93515804	Rat
1598871	Memor5	Memory QTL 5	5.3		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	17	40968017	89341781	Rat
1581512	Cm55	Cardiac mass QTL 55	2.8	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	17	27233445	83975845	Rat
1354629	Scl31	Serum cholesterol level QTL 31	4.1		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	17	38031354	83031354	Rat
2317045	Aia11	Adjuvant induced arthritis QTL 11	4.06		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	17	26522051	71522051	Rat
1600398	Edcs5	Endometrial carcinoma susceptibility QTL 5	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	17	35446949	75762341	Rat
10450503	Bp386	Blood pressure QTL 386		0.28	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	22019705	67019705	Rat
1559055	Bp278	Blood pressure QTL 278		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	23858926	68858926	Rat
152025238	Slep14	Serum leptin concentration QTL 14	4.62		blood leptin amount (VT:0005667)		17	24390595	84432719	Rat
1354638	Insul1	Insulin level QTL 1	4.8		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	38031354	83031354	Rat
61466	Niddm12	Non-insulin dependent diabetes mellitus QTL 12	3.2	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	65154872	93515804	Rat
1354635	Bp245	Blood pressure QTL 245	6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	38031354	83031354	Rat
8552928	Pigfal9	Plasma insulin-like growth factor 1 level QTL 9	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	33104645	78104645	Rat
12904736	Cm121	Cardiac mass QTL 121		0.043	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	17	42388164	87388164	Rat
7394837	Memor18	Memory QTL 18			exploratory behavior trait (VT:0010471)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	17	61091446	68550213	Rat
1300148	Bp192	Blood pressure QTL 192	3.47		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	17	46050126	91050126	Rat
12903980	Cm120	Cardiac mass QTL 120		0.002	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	17	23858926	68858926	Rat
12903981	Am17	Aortic mass QTL 17		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	17	23858926	68858926	Rat
4889891	Eae32	Experimental allergic encephalomyelitis QTL 32	4.8	0.0002	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	17	27233445	72233445	Rat
12903982	Kidm70	Kidney mass QTL 70		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	17	23858926	68858926	Rat
4889894	Eae33	Experimental allergic encephalomyelitis QTL 33	5.2	0.0001	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	17	55604597	93006569	Rat
12903978	Cm118	Cardiac mass QTL 118		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	17	23858926	68858926	Rat
2324621	Coatc5	Coat color QTL 5			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	17	42654895	87654895	Rat
12903979	Cm119	Cardiac mass QTL 119		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	17	23858926	68858926	Rat
1354619	Bp242	Blood pressure QTL 242	6.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	37687877	82687877	Rat
7488963	Bp369	Blood pressure QTL 369		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	63697147	82818564	Rat
1300129	Rf25	Renal function QTL 25	3.03		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	17	41062352	86062352	Rat
152023740	Bp406	Blood pressure QTL 406	6.06		arterial blood pressure trait (VT:2000000)		17	24136127	84432719	Rat
1354663	Bvd5	Brain ventricular dilatation QTL 5	3.51	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	17	32199534	86201342	Rat
7488966	Bp370	Blood pressure QTL 370		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	23858926	68858926	Rat
152023737	Bp405	Blood pressure QTL 405	5.06		arterial blood pressure trait (VT:2000000)			24136127	84432719	Rat
152023736	Bp404	Blood pressure QTL 404	3.78		arterial blood pressure trait (VT:2000000)		17	24136127	84432719	Rat
724528	Uae4	Urinary albumin excretion QTL 4	4.9	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	17	36045537	81045537	Rat
2302365	Gluco40	Glucose level QTL 40	4.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	17	64569820	86954580	Rat

Markers in Region

D17Rat34

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	17	67,180,911 - 67,181,070 (+)	Marker Load Pipeline
mRatBN7.2	17	62,270,788 - 62,270,949 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	58,623,080 - 58,623,238	NCBI	Rnor6.0
Rnor_5.0	17	60,419,106 - 60,419,264	UniSTS	Rnor5.0
RGSC_v3.4	17	73,208,194 - 73,208,353	RGD	RGSC3.4
RGSC_v3.4	17	73,208,195 - 73,208,353	UniSTS	RGSC3.4
Celera	17	55,050,992 - 55,051,150	UniSTS
RGSC_v3.1	17	73,219,027 - 73,219,186	RGD
RH 2.0 Map	17	554.0	RGD
SHRSP x BN Map	17	32.6199	RGD
Cytogenetic Map	17	q12.1-q12.2	UniSTS

D17Rat97

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	17	67,019,466 - 67,019,705 (+)	Marker Load Pipeline
mRatBN7.2	17	62,109,333 - 62,109,574 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	58,467,778 - 58,468,016	NCBI	Rnor6.0
Rnor_5.0	17	60,264,084 - 60,264,322	UniSTS	Rnor5.0
RGSC_v3.4	17	73,041,111 - 73,041,350	RGD	RGSC3.4
RGSC_v3.4	17	73,041,112 - 73,041,350	UniSTS	RGSC3.4
Celera	17	54,890,892 - 54,891,108	UniSTS
RGSC_v3.1	17	73,051,944 - 73,052,183	RGD
SHRSP x BN Map	17	32.6199	RGD
SHRSP x BN Map	17	32.6199	UniSTS
FHH x ACI Map	17	44.4	RGD
Cytogenetic Map	17	q12.1-q12.2	UniSTS

BE120239

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	17	60,262,722 - 60,262,874	NCBI	Rnor5.0
RGSC_v3.4	17	73,039,099 - 73,039,269	UniSTS	RGSC3.4
RH 3.4 Map	17	633.3	UniSTS
Cytogenetic Map	17	q12.1-q12.2	UniSTS

AU048093

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	62,157,148 - 62,157,432 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	58,515,776 - 58,516,059	NCBI	Rnor6.0
Rnor_5.0	17	60,311,802 - 60,312,085	UniSTS	Rnor5.0
RGSC_v3.4	17	73,092,562 - 73,092,845	UniSTS	RGSC3.4
Celera	17	54,938,592 - 54,938,875	UniSTS
Cytogenetic Map	17	q12.1-q12.2	UniSTS

BF403708

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	62,101,192 - 62,101,412 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	58,459,659 - 58,459,878	NCBI	Rnor6.0
Rnor_5.0	17	60,255,923 - 60,256,142	UniSTS	Rnor5.0
RGSC_v3.4	17	73,032,266 - 73,032,485	UniSTS	RGSC3.4
Celera	17	54,882,641 - 54,882,860	UniSTS
Cytogenetic Map	17	q12.1-q12.2	UniSTS

BF416571

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	61,827,053 - 61,827,266 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	58,176,188 - 58,176,400	NCBI	Rnor6.0
Rnor_5.0	17	59,976,179 - 59,976,391	UniSTS	Rnor5.0
RGSC_v3.4	17	72,756,504 - 72,756,716	UniSTS	RGSC3.4
Celera	17	54,609,773 - 54,609,985	UniSTS
Cytogenetic Map	17	q12.1-q12.2	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	8	33	156	37	34	16	23	16	6	135	78	8	143	22	62	18	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008771689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039095307	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U74586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000047512 ⟹ ENSRNOP00000047468

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	66,666,225 - 67,210,749 (-)	Ensembl
mRatBN7.2 Ensembl	17	61,756,067 - 62,300,831 (-)	Ensembl
Rnor_6.0 Ensembl	17	58,104,602 - 58,292,624 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083331 ⟹ ENSRNOP00000073876

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	17	58,104,559 - 58,301,260 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000157779 ⟹ ENSRNOP00000110240

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	66,665,506 - 67,210,749 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000169630 ⟹ ENSRNOP00000101825

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	66,666,225 - 67,210,749 (-)	Ensembl

RefSeq Acc Id:

NM_133302 ⟹ NP_579836

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	66,666,225 - 67,210,874 (-)	NCBI
mRatBN7.2	17	61,756,067 - 62,300,753 (-)	NCBI
Rnor_6.0	17	58,104,602 - 58,653,137 (-)	NCBI
Rnor_5.0	17	59,899,851 - 60,449,163 (-)	NCBI
RGSC_v3.4	17	72,680,982 - 73,238,156 (-)	RGD
Celera	17	54,538,865 - 55,080,965 (-)	RGD

Sequence:

show sequence

AAAGTAGCAGCCCTGCTTCTGGAGCCCAGAGGAAGAGGAGAGAGCTCCAGGGTGCTCAGGACGA
CACGCGGGAATATCTTTCCCAGAGCTTTCTGCCTAAAGAAGGGTTCAGCTTTCCGGCGTGCATC
CGAGGCTTTCAGCTCAACTGGAACCAAGCGACGGGACGATTATAGAGAAGGTGCTTGCTGGCGT
GCTCAGTCCTAAAAAGTGAGACTGCTACTTGATTTGCAAAACCAGAAATACTCCCGGCTGCGGC
CGCAGCAGCAAGACTAAGAAAGGTGAAACTGCTTAAGGACCGGCTCCTCTCTGGGTCTCCCGAC
TGGCATGGCATCTGTCCTGGGGAGTGGCAGAGGGTCTGGAGGGCTAAGCAGTCAGCTCAAATGC
AAGTCCAAGAGGAGAAGGAGGAGAAGGTCCAAGAGGAAAGACAAAGTCAGCATACTGTCAACCT
TCCTCGCTCCTTTCAAGTACCTAAGTCCTGGCACCACAAACACGGAGGATGAAGACAATCTGAG
TACCAGCAGTGCTGAAGTGAAAGAAAACCGAAATGTGAGCAACCTTGGGACCAGGCCCCTGCCC
CCTGGAGACTGGGCCAGAGGCGGCAGCACACCCAGCGTTAAAAGGAAAAGGCCGCTGGAGGAAG
GAAATGGGGGACATTTCTGCAAACTGCAGCTGATCTGGAAAAAACTCTCCTGGTCTATGACACC
CAAGAATGCGCTGGTCCAGCTACATGAGCTGAAGCCGGGTCTTCAGTACCGGATGGTGTCACAG
ACTGGCCCAGTGCACGCCCCAGTTTTCGCCGTGGCTGTAGAAGTAAACGGGCTCACGTTTGAAG
GCACGGGGCCCACTAAGAAGAAGGCCAAGATGCGGGCAGCAGAGATGGCCCTGAAGTCCTTCGT
GCAGTTCCCCAATGCATTCCAGGCCCACCTGGCTATGGGCAGTAGTACCAGTCCGTGCACTGAC
TTCACCTCTGACCAAGCTGACTTCCCAGACACGTTGTTCAAGGAGTTCGAACCATCCTCAAGAA
ACGAGGATTTCCCGGGCTGCTGTCCCGTTGACACTGAGTTTCTGTCCTCTGCCTACCGGCGAGG
ACGGCTGCTCTACCACACACTGGACCTCATGGGCCAGGCTCTGCCTGACAGGTCCAGGCTGGCT
CCAGGGGCACTGGGTGAGAGAAACCCTGTAGTGGTGTTGAATGAATTACGCTCAGGTCTTCGGT
ATGTGTGCCTCTCCGAGACAGCCGAGAAGCCCCGAGTCAAGAGCTTTGTCATGGCTGTGTGCGT
GGACGGGAGGACGTTCGAAGGCTCTGGACGCAGTAAGAAGCTGGCCAAGGGCCAAGCAGCACAA
GCTGCCTTGCAGGCCCTCTTCGACATCCGGCTGCCAGGTCACATACCCAGCAGGAGTAAAAGCA
ACCTCTTGCCACAGGATTTTGCAGACTCTGTGTCTCAGCTGGTCACACAGAAGTTCCGTGAACT
GACAGTCGGCCTGACATCTGTGTATGCCCGCCACAAAACACTGGCAGGAATCGTCATGACCAAA
GGCTTGGACACCAAACAAGCACAGGTCATCGTTCTGTCCTCTGGGACCAAGTGTATCAGCGGTG
AGCACATCAGTGACCAGGGGCTGGTTGTCAACGACTGTCACGCTGAGATTGTGGCAAGGCGAGC
ATTTCTTCACTTCCTCTACACTCAGCTGGAGCTGCACTTGAGCAAGCATCAAGAGGACCCCGAG
AGATCAATATTCATCCGTGTAAAGGAAGGAGGCTACAGGCTGCGAGAAAACATCCTCTTCCACC
TCTACGTGAGCACATCCCCTTGTGGAGACGCCAGACTCAACTCTCCCTATGAAATCACCATAGA
CTTGAACAGCAGCAAACACATCGTCAGGAAGTTCCGAGGGCACCTGCGCACCAAGATTGAGTCT
GGGGAAGGAACAGTCCCTGTGCGGGGCCCCAGTGCAGTCCAGACATGGGATGGCATCCTGCTGG
GGGAGCAGCTAGTCACCATGTCCTGCACAGACAAGATTGCCAGCTGGAATGTGCTGGGACTACA
AGGCGCTCTCCTCTGTCACTTCATCGAGCCTGTGTACCTCCATAGCATCATTGTGGGAAGCCTG
CATCACACGGGCCACCTTGCACGGGTCATGAGCCACAGGATGGAGGGCATCGGCCAACTGCCTG
CCTCATACCGACAAAACAGGCCTCTCCTTAGTGGTGTGAGTAACGCCGAGGCCCGGCAGCCAGG
AAAGTCTCCCCACTTCAGTGCCAACTGGGTCGTAGGCAGTGCCGACCTGGAGATCATTAATGCC
ACAACTGGGAAGAGGAGCTGTGGGGGTTCATCCCGGCTCTGCAAGCACGTGTTTTCTGCTCGGT
GGGCACGGCTGCATGGTAGGCTAAGCACACGGATCCCAGGCCACGGAGACACACCCTCCATGTA
CTGTGAAGCCAAGCGGGGGGCTCACACCTACCAGTCTGTTAAACAGCAGCTCTTCAAGGCTTTT
CAGAAAGCTGGTCTTGGCACCTGGGTGAGAAAGCCACCAGAGCAAGATCAGTTTCTACTAAGTC
TCTAAGTTGCTAGACTCCTTGGCTATTGGACCAGAGTGAGATGCCCGGAGAGGATGAAGCCGTA
TGATGGTGTGGTGTGTCCATCAGTTCTTGACCTTTGTTCTCCTTCATTGTTCAGGAACACATGG
CCTCATGTGTGGATGAGAGACTACACTTGAGT

hide sequence

RefSeq Acc Id:

XM_017600442 ⟹ XP_017455931

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	66,666,373 - 67,211,102 (-)	NCBI
mRatBN7.2	17	61,750,437 - 62,300,982 (-)	NCBI
Rnor_6.0	17	58,104,787 - 58,293,162 (-)	NCBI

Sequence:

show sequence

TGTCTGTGTGTATGTATGTGTGTGTGTATGTGTTTGCTTCTCAACTTCTACTTTTTTATGTCAT
ATTTATAACTAAAGAGCTCAGAACAAATATTCCACCAATGAGAGGGGTTGGAAGAATTCTTGCC
TTTGTTGGGACAAGTCTCCTAGTTCTGGGATTGTATTACTGAATTTTGATTATTTTAGGAACTC
CCTTATATGGTAAGTGTTAGCTAACTCACCTGTAAATAGATGAGATGTTTTAACCCTGAAGTCA
ACTATTGAAAGTTTTCAGGGATGTGGAACAAGGTCACCGAAATGCCAAAAACAAATAAATATAT
ATGTAAAGGAAGAGAGATGGAAATCATAATTAAATTGAATGGAGAGAGGAATTTGATAAAAACG
CTGTCCGAAATTCAATTTAAAAAAAAGAAATGGAACCACAATGAAGTATCTGCCGCCACTTCTC
TGTCCCAACCTCTGGGTAATAACATAAGAAAGCACTGGGTTTTTCTGAAACTCGATGTCAAAAG
TGCACCTCCTCTTCTTTCTCTTTCCAGACAAAGTCAGCATACTGTCAACCTTCCTCGCTCCTTT
CAAGTACCTAAGTCCTGGCACCACAAACACGGAGGATGAAGACAATCTGAGTACCAGCAGTGCT
GAAGTGAAAGAAAACCGAAATGTGAGCAACCTTGGGACCAGGCCCCTGCCCCCTGGAGACTGGG
CCAGAGGCGGCAGCACACCCAGCGTTAAAAGGAAAAGGCCGCTGGAGGAAGGAAATGGGGGACA
TTTCTGCAAACTGCAGCTGATCTGGAAAAAACTCTCCTGGTCTATGACACCCAAGAATGCGCTG
GTCCAGCTACATGAGCTGAAGCCGGGTCTTCAGTACCGGATGGTGTCACAGACTGGCCCAGTGC
ACGCCCCAGTTTTCGCCGTGGCTGTAGAAGTAAACGGGCTCACGTTTGAAGGCACGGGGCCCAC
TAAGAAGAAGGCCAAGATGCGGGCAGCAGAGATGGCCCTGAAGTCCTTCGTGCAGTTCCCCAAT
GCATTCCAGGCCCACCTGGCTATGGGCAGTAGTACCAGTCCGTGCACTGACTTCACCTCTGACC
AAGCTGACTTCCCAGACACGTTGTTCAAGGAGTTCGAACCATCCTCAAGAAACGAGGATTTCCC
GGGCTGCTGTCCCGTTGACACTGAGTTTCTGTCCTCTGCCTACCGGCGAGGACGGCTGCTCTAC
CACACACTGGACCTCATGGGCCAGGCTCTGCCTGACAGGTCCAGGCTGGCTCCAGGGGCACTGG
GTGAGAGAAACCCCGTAGTGGTGTTGAATGAATTACGCTCAGGTCTTCGGTATGTGTGCCTCTC
CGAGACAGCCGAGAAGCCCCGAGTCAAGAGCTTTGTCATGGCTGTGTGCGTGGACGGGAGGACG
TTCGAAGGCTCTGGACGCAGTAAGAAGCTGGCCAAGGGCCAAGCAGCACAAGCTGCCTTGCAGG
CCCTCTTCGACATCCGGCTGCCAGGTCACATACCCAGCAGGAGTAAAAGCAACCTCTTGCCACA
GGATTTTGCAGACTCTGTGTCTCAGCTGGTCACACAGAAGTTCCGTGAACTGACAGTCGGCCTG
ACATCTGTGTATGCCCGCCACAAAACACTGGCAGGAATCGTCATGACCAAAGGCTTGGACACCA
AACAAGCACAGGTCATCGTTCTGTCCTCTGGGACCAAGTGTATCAGCGGTGAGCACATCAGTGA
CCAGGGGCTGGTTGTCAACGACTGTCACGCTGAGATTGTGGCAAGGCGAGCATTTCTTCACTTC
CTCTACACTCAGCTGGAGCTGCACTTGAGCAAGCATCAAGAGGACCCCGAGAGATCAATATTCA
TCCGTGTAAAGGAAGGAGGCTACAGGCTGCGAGAAAACATCCTCTTCCACCTCTACGTGAGCAC
ATCCCCTTGTGGAGACGCCAGACTCAACTCTCCCTATGAAATCACCACAGACTTGAACAGCAGC
AAACACATCGTCAGGAAGTTCCGAGGGCACCTGCGCACCAAGATTGAGTCTGGGGAAGGAACAG
TCCCTGTGCGGGGCCCCAGTGCAGTCCAGACATGGGATGGCATCCTGCTGGGGGAGCAGCTAGT
CACCATGTCCTGCACAGACAAGATTGCCAGCTGGAATGTGCTGGGACTACAAGGCGCTCTCCTC
TGTCACTTCATCGAGCCTGTGTACCTCCATAGCATCATTGTGGGAAGCCTGCATCACACGGGCC
ACCTTGCACGGGTCATGAGCCACAGGATGGAGGGCATCGGCCAACTGCCTGCCTCATACCGACA
AAACAGGCCTCTCCTTAGTGGTGTGAGTAACGCCGAGGCCCGGCAGCCAGGAAAGTCTCCCCAC
TTCAGTGCCAACTGGGTCGTAGGCAGTGCCGACCTGGAGATCATTAATGCCACAACTGGGAAGA
GGAGCTGTGGGGGTTCATCCCGGCTCTGCAAGCACGTGTTTTCTGCTCGGTGGGCACGGCTGCA
TGCTAAGCACACGGATCCCAGGCCACGGAGACACACCCTCCATGTACTGTGAAGCCAAGCGGGG
GGCTCACACCTACCAGTCTGTTAAACAGCAGCTCTTCAAGGCTTTTCAGAAAGCTGGTCTTGGC
ACCTGGGTGAGAAAGCCACCA

hide sequence

RefSeq Acc Id:

XM_039095307 ⟹ XP_038951235

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	66,660,586 - 67,211,104 (-)	NCBI
mRatBN7.2	17	61,750,437 - 62,300,984 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_579836	(Get FASTA)	NCBI Sequence Viewer
	XP_017455931	(Get FASTA)	NCBI Sequence Viewer
	XP_038951235	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB41862	(Get FASTA)	NCBI Sequence Viewer
	EDL86441	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000047468
	ENSRNOP00000110240
GenBank Protein	P97616	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_579836 ⟸ NM_133302

- UniProtKB:

P97616 (UniProtKB/Swiss-Prot), A6KRP0 (UniProtKB/TrEMBL), F1LSW5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASVLGSGRGSGGLSSQLKCKSKRRRRRRSKRKDKVSILSTFLAPFKYLSPGTTNTEDEDNLST
SSAEVKENRNVSNLGTRPLPPGDWARGGSTPSVKRKRPLEEGNGGHFCKLQLIWKKLSWSMTPK
NALVQLHELKPGLQYRMVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAEMALKSFVQ
FPNAFQAHLAMGSSTSPCTDFTSDQADFPDTLFKEFEPSSRNEDFPGCCPVDTEFLSSAYRRGR
LLYHTLDLMGQALPDRSRLAPGALGERNPVVVLNELRSGLRYVCLSETAEKPRVKSFVMAVCVD
GRTFEGSGRSKKLAKGQAAQAALQALFDIRLPGHIPSRSKSNLLPQDFADSVSQLVTQKFRELT
VGLTSVYARHKTLAGIVMTKGLDTKQAQVIVLSSGTKCISGEHISDQGLVVNDCHAEIVARRAF
LHFLYTQLELHLSKHQEDPERSIFIRVKEGGYRLRENILFHLYVSTSPCGDARLNSPYEITIDL
NSSKHIVRKFRGHLRTKIESGEGTVPVRGPSAVQTWDGILLGEQLVTMSCTDKIASWNVLGLQG
ALLCHFIEPVYLHSIIVGSLHHTGHLARVMSHRMEGIGQLPASYRQNRPLLSGVSNAEARQPGK
SPHFSANWVVGSADLEIINATTGKRSCGGSSRLCKHVFSARWARLHGRLSTRIPGHGDTPSMYC
EAKRGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQDQFLLSL

hide sequence

RefSeq Acc Id:	XP_017455931 ⟸ XM_017600442
- Peptide Label:	isoform X1
- UniProtKB:	A6KRP0 (UniProtKB/TrEMBL), F1LSW5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSKVHLLFFLFPDKVSILSTFLAPFKYLSPGTTNTEDEDNLSTSSAEVKENRNVSNLGTRPLPP GDWARGGSTPSVKRKRPLEEGNGGHFCKLQLIWKKLSWSMTPKNALVQLHELKPGLQYRMVSQT GPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAEMALKSFVQFPNAFQAHLAMGSSTSPCTDF TSDQADFPDTLFKEFEPSSRNEDFPGCCPVDTEFLSSAYRRGRLLYHTLDLMGQALPDRSRLAP GALGERNPVVVLNELRSGLRYVCLSETAEKPRVKSFVMAVCVDGRTFEGSGRSKKLAKGQAAQA ALQALFDIRLPGHIPSRSKSNLLPQDFADSVSQLVTQKFRELTVGLTSVYARHKTLAGIVMTKG LDTKQAQVIVLSSGTKCISGEHISDQGLVVNDCHAEIVARRAFLHFLYTQLELHLSKHQEDPER SIFIRVKEGGYRLRENILFHLYVSTSPCGDARLNSPYEITTDLNSSKHIVRKFRGHLRTKIESG EGTVPVRGPSAVQTWDGILLGEQLVTMSCTDKIASWNVLGLQGALLCHFIEPVYLHSIIVGSLH HTGHLARVMSHRMEGIGQLPASYRQNRPLLSGVSNAEARQPGKSPHFSANWVVGSADLEIINAT TGKRSCGGSSRLCKHVFSARWARLHAKHTDPRPRRHTLHVL hide sequence

Ensembl Acc Id:

ENSRNOP00000047468 ⟸ ENSRNOT00000047512

Ensembl Acc Id:

ENSRNOP00000073876 ⟸ ENSRNOT00000083331

RefSeq Acc Id:	XP_038951235 ⟸ XM_039095307
- Peptide Label:	isoform X2
- UniProtKB:	A6KRP0 (UniProtKB/TrEMBL), F1LSW5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000101825 ⟸ ENSRNOT00000169630

Ensembl Acc Id:

ENSRNOP00000110240 ⟸ ENSRNOT00000157779

Protein Domains

A to I editase DRBM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P97616-F1-model_v2	AlphaFold	P97616	1-746	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621519	AgrOrtholog
BioCyc Gene	G2FUF-8880	BioCyc
Ensembl Genes	ENSRNOG00000030775	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000047512	ENTREZGENE
	ENSRNOT00000157779	ENTREZGENE
Gene3D-CATH	3.30.160.20	UniProtKB/Swiss-Prot
InterPro	A_deamin	UniProtKB/Swiss-Prot
	ADAR3_DSRM_1	UniProtKB/Swiss-Prot
	dsRBD_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:117088	UniProtKB/Swiss-Prot
NCBI Gene	117088	ENTREZGENE
PANTHER	DOUBLE-STRANDED RNA-SPECIFIC EDITASE B2	UniProtKB/Swiss-Prot
	EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN	UniProtKB/Swiss-Prot
Pfam	A_deamin	UniProtKB/Swiss-Prot
	dsrm	UniProtKB/Swiss-Prot
PhenoGen	Adarb2	PhenoGen
PROSITE	A_DEAMIN_EDITASE	UniProtKB/Swiss-Prot
	DS_RBD	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000030775	RatGTEx
SMART	ADEAMc	UniProtKB/Swiss-Prot
	DSRM	UniProtKB/Swiss-Prot
Superfamily-SCOP	dsRNA-binding domain-like	UniProtKB/Swiss-Prot
UniProt	A0ABK0LEP7_RAT	UniProtKB/TrEMBL
	A0ABK0M5S9_RAT	UniProtKB/TrEMBL
	A6KRP0	ENTREZGENE, UniProtKB/TrEMBL
	F1LSW5	ENTREZGENE, UniProtKB/TrEMBL
	P97616	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-08-03	Adarb2	adenosine deaminase RNA specific B2	Adarb2	adenosine deaminase, RNA-specific, B2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-01-09	Adarb2	adenosine deaminase, RNA-specific, B2	Adar3	adenosine deaminase 3, RNA dependent	Symbol and Name updated to reflect Human and Mouse nomenclature	625702	APPROVED
2002-08-07	Adar3				Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed only in the brain, highest levels in olfactory bulb and thalamus	632263
gene_product	member of the RNA-specific adenosine deaminase family	632263

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD