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Gene: Psmd9 (proteasome 26S subunit, non-ATPase 9) Rattus norvegicus

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Symbol:

Psmd9

Name:

proteasome 26S subunit, non-ATPase 9

RGD ID:

621110

Description:

Enables bHLH transcription factor binding activity and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II; regulation of insulin secretion; and type B pancreatic cell apoptotic process. Located in nucleus. Orthologous to human PSMD9 (proteasome 26S subunit, non-ATPase 9); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

26S proteasome non-ATPase regulatory subunit 9; 26S proteasome non-ATPase regulatory subunit 9-like; 26S proteasome regulatory subunit p27; Bridge; Bridge-1; LOC103694906; proteasome (prosome, macropain) 26S subunit, non-ATPase, 9; transactivating protein Bridge-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PSMD9 (proteasome 26S subunit, non-ATPase 9)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther
Mus musculus (house mouse):	Psmd9 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Psmd9 (proteasome 26S subunit, non-ATPase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PSMD9 (proteasome 26S subunit, non-ATPase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PSMD9 (proteasome 26S subunit, non-ATPase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Psmd9 (proteasome 26S subunit, non-ATPase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PSMD9 (proteasome 26S subunit, non-ATPase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PSMD9 (proteasome 26S subunit, non-ATPase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Psmd9 (proteasome 26S subunit, non-ATPase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Psmd9 (proteasome 26S subunit, non-ATPase 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Psmd9 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 9)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PSMD9 (proteasome 26S subunit, non-ATPase 9)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	psmd9 (proteasome 26S subunit, non-ATPase 9)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	NAS2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	NAS2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9588	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9588	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	psmd-9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	psmd-9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	psmd9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	psmd9	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	38,998,027 - 39,018,340 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	38,998,030 - 39,018,679 (-)	Ensembl				GRCr8
mRatBN7.2	12	33,337,182 - 33,357,468 (-)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	12	34,518,576 - 34,537,128 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	35,129,937 - 35,148,492 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	34,181,818 - 34,200,369 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	38,786,539 - 38,805,121 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	38,786,540 - 38,805,121 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	40,670,892 - 40,699,374 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	34,472,250 - 34,500,731 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	35,020,854 - 35,039,503 (-)	NCBI		Celera
RGSC_v3.1	12	34,335,640 - 34,364,118 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

ciguatoxin CTX1B (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

diclofenac (ISO)

doxorubicin (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

ethanol (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

isoprenaline (EXP)

ivermectin (ISO)

linalool (ISO)

Mesaconitine (EXP)

methimazole (EXP)

methotrexate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

monosodium L-glutamate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (ISO)

nefazodone (EXP)

paracetamol (EXP,ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

phenobarbital (ISO)

phlorizin (ISO)

pirinixic acid (ISO)

propiconazole (EXP)

rotenone (EXP)

silicon dioxide (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

T-2 toxin (EXP)

thapsigargin (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of insulin secretion (IMP)

positive regulation of DNA-templated transcription (IDA)

positive regulation of insulin secretion (IDA)

positive regulation of transcription by RNA polymerase II (IDA,IMP)

proteasome regulatory particle assembly (IBA,IEA,ISO,ISS)

type B pancreatic cell apoptotic process (IMP)

Cellular Component

cytoplasm (IBA)

cytosol (ISO)

nucleus (IBA,IDA)

proteasome regulatory particle, base subcomplex (ISO)

Molecular Function

bHLH transcription factor binding (IDA,IPI)

protein binding (IPI,ISO)

transcription coactivator activity (IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Interactions with p300 enhance transcriptional activation by the PDZ-domain coactivator Bridge-1.	Lee JH, etal., J Endocrinol. 2005 Nov;187(2):283-92.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1).	Stanojevic V, etal., Mol Cell Endocrinol. 2005 Jun 15;237(1-2):67-74.
8.	Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription.	Thomas MK, etal., Mol Cell Biol 1999 Dec;19(12):8492-504.
9.	Overexpression of the coactivator bridge-1 results in insulin deficiency and diabetes.	Volinic JL, etal., Mol Endocrinol. 2006 Jan;20(1):167-82. Epub 2005 Aug 11.

Additional References at PubMed

PMID:19490896	PMID:19782349

Genomics

Comparative Map Data

Psmd9
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	38,998,027 - 39,018,340 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	38,998,030 - 39,018,679 (-)	Ensembl				GRCr8
mRatBN7.2	12	33,337,182 - 33,357,468 (-)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	12	34,518,576 - 34,537,128 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	35,129,937 - 35,148,492 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	34,181,818 - 34,200,369 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	38,786,539 - 38,805,121 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	38,786,540 - 38,805,121 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	40,670,892 - 40,699,374 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	34,472,250 - 34,500,731 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	35,020,854 - 35,039,503 (-)	NCBI		Celera
RGSC_v3.1	12	34,335,640 - 34,364,118 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

PSMD9
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	121,888,790 - 121,918,297 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	121,888,726 - 121,918,297 (+)	Ensembl			hg38	GRCh38
GRCh37	12	122,326,696 - 122,356,203 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	120,811,029 - 120,840,154 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	120,789,365 - 120,818,490	NCBI
Celera	12	121,962,584 - 121,993,388 (+)	NCBI		Celera
Cytogenetic Map	12	q24.31	NCBI
HuRef	12	119,337,911 - 119,366,980 (+)	NCBI		HuRef
CHM1_1	12	122,294,280 - 122,323,411 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	121,885,089 - 121,914,595 (+)	NCBI		T2T-CHM13v2.0

Psmd9
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	123,366,253 - 123,388,189 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	123,307,476 - 123,388,194 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	123,228,190 - 123,250,126 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	123,169,413 - 123,250,131 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	123,678,199 - 123,700,135 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	123,488,864 - 123,509,579 (+)	NCBI		MGSCv36	mm8
Celera	5	120,316,542 - 120,337,789 (+)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	62.85	NCBI

Psmd9
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	6,554,607 - 6,567,481 (-)	Ensembl
ChiLan1.0	NW_004955482	6,555,902 - 6,567,481 (-)	NCBI	ChiLan1.0	ChiLan1.0

PSMD9
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	129,977,069 - 130,004,853 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	129,973,447 - 130,001,227 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	119,490,380 - 119,519,318 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	122,859,940 - 122,887,705 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	122,859,940 - 122,887,703 (+)	Ensembl			panPan2	panpan1.1

PSMD9
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	7,376,154 - 7,400,655 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	7,377,413 - 7,400,573 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	7,535,989 - 7,560,487 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	7,627,447 - 7,651,967 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	7,627,019 - 7,651,928 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	7,559,629 - 7,584,337 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	7,650,056 - 7,674,566 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	7,606,014 - 7,630,570 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Psmd9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	156,967,501 - 156,983,428 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936558	2,495,982 - 2,511,985 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936558	2,495,998 - 2,511,911 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSMD9
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	30,793,524 - 30,822,127 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	30,793,521 - 30,822,135 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	32,600,110 - 32,627,319 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PSMD9
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	117,246,171 - 117,275,766 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	117,246,186 - 117,275,757 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666136	74,714 - 104,852 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psmd9
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	22,233,497 - 22,250,421 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	22,233,620 - 22,247,943 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Psmd9
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	30,597,143 - 30,616,417 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Psmd9
168 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	321
Count of miRNA genes:	198
Interacting mature miRNAs:	216
Transcripts:	ENSRNOT00000057716
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	29775522	42298555	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
1556747	Calcic1	Intracellular calcium level QTL 1		3.6	platelet calcium amount (VT:0010500)	platelet intracellular calcium level (CMO:0000922)	12	33700432	46784661	Rat
631829	Alc6	Alcohol consumption QTL 6	4.7		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	34243475	43352593	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat

Markers in Region

RH139716

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	33,339,274 - 33,339,466 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	38,786,563 - 38,786,754	NCBI	Rnor6.0
Rnor_5.0	12	40,670,916 - 40,671,107	UniSTS	Rnor5.0
RGSC_v3.4	12	34,500,516 - 34,500,707	UniSTS	RGSC3.4
Celera	12	35,020,878 - 35,021,069	UniSTS
RH 3.4 Map	12	594.0	UniSTS
Cytogenetic Map	12	q16	UniSTS

BI276461

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	12	38,999,659 - 38,999,834 (+)	Marker Load Pipeline
mRatBN7.2	12	33,338,816 - 33,338,991 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	38,786,105 - 38,786,279	NCBI	Rnor6.0
Rnor_5.0	12	40,670,458 - 40,670,632	UniSTS	Rnor5.0
RGSC_v3.4	12	34,500,991 - 34,501,165	UniSTS	RGSC3.4
Celera	12	35,020,420 - 35,020,594	UniSTS
RH 3.4 Map	12	597.7	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_130430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC123330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF067728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000057716 ⟹ ENSRNOP00000054528

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	12	38,786,540 - 38,805,121 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000134832 ⟹ ENSRNOP00000105159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	39,004,159 - 39,018,679 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000140737 ⟹ ENSRNOP00000109118

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	38,998,030 - 39,018,264 (-)	Ensembl

RefSeq Acc Id:

NM_130430 ⟹ NP_569114

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	39,000,090 - 39,018,264 (-)	NCBI
mRatBN7.2	12	33,339,247 - 33,357,421 (-)	NCBI
Rnor_6.0	12	38,786,539 - 38,805,121 (-)	NCBI
Rnor_5.0	12	40,670,892 - 40,699,374 (-)	NCBI
RGSC_v3.4	12	34,472,250 - 34,500,731 (+)	RGD
Celera	12	35,020,854 - 35,039,503 (-)	RGD

Sequence:

show sequence

GAATTCGCGGCGCGTCGACCTCAAGAGGCAGAGGCACATAGAGAAACCCTATCTTGAAAAACGG
GGGAGGGAGAAACAGGGGCAGAATGAAAAAGGGAGGAAGGAAGAAAGGAAGGAATGAGAAAGAA
AAGTGGAAATAAGTCACGTATAAAACGAGAGTTAAAGCCTACGTCATGGGGTTGGGGATTTAGC
TCAGTGGTAGAGCGCTTGCCTAGCAAGCGCAAGGCCCTGGGTTCGGTCCCCAGCTCCGGAAAAA
AAAAAAAAAAAGAAAAAAAAAAAAGCCTACGTCATCCTGTCTCCACTTAGCTCTGCCGGGTCAT
CTGAAAACCACGTGGTCTATTTAGCTGGAGTTTCCGGTGACCTCGCCCCACCTTCAAACTCAGT
ACTTGTGCATTGGCTGAAGTATTTTGTCCCTTGGGAGGACCCGTAGCTCCAGCCTCCCGGTGTC
CGTAGCCGGGAAACCTGGCGTCCGGCGTTTTAGGCTGAGGTCCGCGATGTCGAGTGAGGAAGTC
CGGCACCGGGCAGAGTCCTCTGAGGCCCGTGCGGCCGCGGTCAGCGACATCCAGGAGCTGATGC
GACGCAAGGAGGAAATCGAGGCGCAGATCAAGGCTAATTACGACGTCCTCGAGAGCCAAAAAGG
AATTGGCATGAACGAGCCTCTAGTGGACTGCGAGGGCTACCCCCGGGCAGATGTGGATTTGTAT
CAGGTCCGAACAGCAAGGCACAACATCATCTGTCTCCAGAATGATCACAAGGCACTGATGAAGC
AGGTGGAGGAGGCCCTACACCAGCTACATGCTCGGGACAAAGAGAAGCAGGCTCGGGACATGGC
TGAAGCCCGAGAAGAGGCCATGAACCGTAGGCTGGCCTCGGACAGTCCCGCCCTACCCAAGGCC
TTTGCCAGAGTGAACAGTATCAGCCCTGGTTCCCCAGCCAGTATTGCGGGCCTGCAAGTGGATG
ATGAAATTGTGGAGTTCGGCTCTGTGAACACCCAAAACTTCCAGTCTCTGCAGAACGTGGGCAC
TGTGGTGCAGCACAGCGAGGGGAAGCCCCTGAATGTCATGGTGATCCGCAGAGGGGAGAAGCAC
CAGCTCAGACTGACTCCCACCCGCTGGGCAGGAAAAGGACTGCTGGGCTGCAATATTACCCCTC
TCCAAAGATGACTGCTTCCTGGGAGCTGCAGGAGAGCTTCTTCAGCTGGGCCCGCGCTTGGCCT
GGGGGATTTCCTCATTCTCTCGGCTCCCTCAAGTGTAAGGATCTGGAAGAGAGTGGCGGACGCC
TGAGCGTCGAGGTGGAAGAGACGCTTTGGCTGCCTGATGTAGTCTCTGGGTTGAGGCATTATTA
AAAATGTGGTTTGTGCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XR_005491591

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,998,027 - 39,018,340 (-)	NCBI
mRatBN7.2	12	33,337,182 - 33,357,467 (-)	NCBI

RefSeq Acc Id:

XR_005491592

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	38,999,604 - 39,018,306 (-)	NCBI
mRatBN7.2	12	33,337,536 - 33,357,468 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_569114	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD32925	(Get FASTA)	NCBI Sequence Viewer
	EDM13649	(Get FASTA)	NCBI Sequence Viewer
	EDM13650	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000109118
GenBank Protein	Q9WTV5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_569114 ⟸ NM_130430

- UniProtKB:

Q9WTV5 (UniProtKB/Swiss-Prot), A6J160 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSEEVRHRAESSEARAAAVSDIQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPR
ADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHARDKEKQARDMAEAREEAMNRRLASDS
PALPKAFARVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLQNVGTVVQHSEGKPLNVMVI
RRGEKHQLRLTPTRWAGKGLLGCNITPLQR

hide sequence

Ensembl Acc Id:

ENSRNOP00000054528 ⟸ ENSRNOT00000057716

Ensembl Acc Id:

ENSRNOP00000105159 ⟸ ENSRNOT00000134832

Ensembl Acc Id:

ENSRNOP00000109118 ⟸ ENSRNOT00000140737

Protein Domains

Nas2 N-terminal PDZ

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9WTV5-F1-model_v2	AlphaFold	Q9WTV5	1-222	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698632

Promoter ID:

EPDNEW_R9156

Type:

initiation region

Name:

Psmd9_1

Description:

proteasome 26S subunit, non-ATPase 9

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	38,804,661 - 38,804,721	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621110	AgrOrtholog
BioCyc Gene	G2FUF-19296	BioCyc
Ensembl Genes	ENSRNOG00000001339	Ensembl
	ENSRNOG00000077689	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000140737	ENTREZGENE
Gene3D-CATH	2.30.42.10	UniProtKB/Swiss-Prot
	6.10.140.1710	UniProtKB/Swiss-Prot
InterPro	Nas2_N	UniProtKB/Swiss-Prot
	PDZ	UniProtKB/Swiss-Prot
	PDZ_6	UniProtKB/Swiss-Prot
	PDZ_sf	UniProtKB/Swiss-Prot
	PSMD9	UniProtKB/Swiss-Prot
KEGG Report	rno:161475	UniProtKB/Swiss-Prot
NCBI Gene	161475	ENTREZGENE
PANTHER	26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9	UniProtKB/Swiss-Prot
	PTHR12651	UniProtKB/Swiss-Prot
Pfam	Nas2_N	UniProtKB/Swiss-Prot
	PDZ_6	UniProtKB/Swiss-Prot
PhenoGen	Psmd9	PhenoGen
RatGTEx	ENSRNOG00000001339	RatGTEx
	ENSRNOG00000077689	RatGTEx
SMART	PDZ	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50156	UniProtKB/Swiss-Prot
UniProt	A0ABK0LQ47_RAT	UniProtKB/TrEMBL
	A0ABK0M2X8_RAT	UniProtKB/TrEMBL
	A6J160	ENTREZGENE, UniProtKB/TrEMBL
	A6J161_RAT	UniProtKB/TrEMBL
	PSMD9_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Psmd9	proteasome 26S subunit, non-ATPase 9	LOC103694906	26S proteasome non-ATPase regulatory subunit 9-like	Data merged from RGD:9385973	737654	PROVISIONAL
2015-08-19	Psmd9	proteasome 26S subunit, non-ATPase 9	Psmd9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103694906	26S proteasome non-ATPase regulatory subunit 9-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-02-26	Psmd9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Psmd9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a PDZ domain	633869

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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