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Gene: Ptprr (protein tyrosine phosphatase, receptor type, R) Rattus norvegicus

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Symbol:

Ptprr

Name:

protein tyrosine phosphatase, receptor type, R

RGD ID:

620780

Description:

Predicted to enable protein kinase binding activity and protein tyrosine phosphatase activity. Involved in neuron differentiation. Predicted to be located in cytoplasm and membrane. Predicted to be active in cell junction; cytosol; and plasma membrane. Orthologous to human PTPRR (protein tyrosine phosphatase receptor type R); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

PC12-PTP1; Pcptp1; protein tyrosine phosphatase PCPTP1; protein-tyrosine phosphatase PCPTP1; R-PTP-R; receptor-type tyrosine-protein phosphatase R; tyrosine phosphatase CBPTP

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PTPRR (protein tyrosine phosphatase receptor type R)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Ptprr (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ptprr (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PTPRR (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PTPRR (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ptprr (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PTPRR (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PTPRR (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ptprr (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ptprr (protein tyrosine phosphatase receptor type R)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	LBHD1 (LBH domain containing 1)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Ptprr (protein tyrosine phosphatase receptor type R)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PTPRR (protein tyrosine phosphatase receptor type R)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ptprr (protein tyrosine phosphatase, receptor type, r)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ptprr (protein tyrosine phosphatase, receptor type, r)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F25H5.7	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)
Caenorhabditis elegans (roundworm):	M04G7.2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)
Caenorhabditis elegans (roundworm):	T27A3.5	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)
Drosophila melanogaster (fruit fly):	PTP-ER	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Caenorhabditis elegans (roundworm):	ZK354.8	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)
Caenorhabditis elegans (roundworm):	M01A12.4	Alliance	DIOPT (Ensembl Compara\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	ptprr	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	ptprr	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

NCBI Annotation Information:

Note: There is an assembly problem in the Rnor_6.0 reference genome assembly, and therefore, annotation of this gene is split across NW_007905857.1 and NW_007905858.1 in NCBI's Rattus norvegicus Annotation Release 105. [17 Jun 2015]

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	53,548,611 - 53,815,632 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	53,548,629 - 53,815,629 (+)	Ensembl				GRCr8
mRatBN7.2	7	51,662,595 - 51,929,605 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	51,662,595 - 51,929,603 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	53,569,319 - 53,836,323 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	55,772,411 - 56,039,410 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	55,550,399 - 55,817,402 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	59,039,717 - 59,325,925 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	59,039,720 - 59,325,947 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	59,207,155 - 59,335,376 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	7	59,041,711 - 59,084,462 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	55,324,246 - 55,612,945 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	48,446,749 - 48,710,763 (+)	NCBI		Celera
RGSC_v3.1	7	55,344,975 - 55,633,672 (+)	NCBI
Cytogenetic Map	7	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-palmitoylglycerol (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

Ampullosporin (EXP)

arsenite(3-) (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (EXP,ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

chromium(6+) (ISO)

copper atom (ISO)

copper(0) (ISO)

Cuprizon (EXP)

curcumin (ISO)

dexamethasone (EXP)

dibenz[a,h]anthracene (ISO)

dichlorine (EXP)

dioxygen (ISO)

diuron (EXP)

ethanol (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

graphite (EXP)

GW 4064 (ISO)

ketamine (EXP)

lead(0) (ISO)

methimazole (EXP)

methotrexate (ISO)

N,N-diethyl-m-toluamide (EXP)

nitroglycerin (EXP)

ozone (EXP,ISO)

paracetamol (EXP)

paraquat (EXP)

pentanal (ISO)

permethrin (EXP)

progesterone (EXP,ISO)

raloxifene (ISO)

resveratrol (EXP)

rotenone (ISO)

sarin (ISO)

sevoflurane (EXP)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

Soman (EXP)

sulfadimethoxine (EXP)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (EXP)

thiram (ISO)

trichloroethene (EXP)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ERBB2 signaling pathway (IEA,ISO)

in utero embryonic development (IEA,ISO,ISS)

negative regulation of epithelial cell migration (IEA,ISO)

negative regulation of ERK1 and ERK2 cascade (IEA,ISO)

nervous system development (IEP)

neuron differentiation (IEP)

protein dephosphorylation (ISO)

regulation of homophilic cell adhesion (ISO)

signal transduction (IBA)

Cellular Component

cell junction (IBA,IEA,ISO)

cytoplasm (IEA)

cytosol (IBA,IEA,ISO)

endomembrane system (IEA)

plasma membrane (IBA,IEA,ISO)

Molecular Function

hydrolase activity (IEA)

phosphoprotein phosphatase activity (IEA)

protein binding (IPI,ISO)

protein kinase binding (IBA,IEA,ISO)

protein tyrosine phosphatase activity (IBA,IEA,ISO,TAS)

Molecular Pathway Annotations Click to see Annotation Detail View

mitogen activated protein kinase signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Interaction between chicken protein tyrosine phosphatase 1 (CPTP1)-like rat protein phosphatase 1 (PTP1) and p60(v-src) in v-src-transformed Rat-1 fibroblasts.	Jung EJ and Kim CW, Exp Mol Med. 2002 Dec 31;34(6):476-80.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	A neuronal protein tyrosine phosphatase induced by nerve growth factor.	Sharma E and Lombroso PJ, J Biol Chem 1995 Jan 6;270(1):49-53.
9.	Cloning and expression of PCPTP1 encoding protein tyrosine phosphatase.	Shiozuka K, etal., Gene 1995 Sep 11;162(2):279-84.

Additional References at PubMed

PMID:7832766	PMID:10601328	PMID:12477932	PMID:21724833	PMID:22664934

Genomics

Comparative Map Data

Ptprr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	53,548,611 - 53,815,632 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	53,548,629 - 53,815,629 (+)	Ensembl				GRCr8
mRatBN7.2	7	51,662,595 - 51,929,605 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	51,662,595 - 51,929,603 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	53,569,319 - 53,836,323 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	55,772,411 - 56,039,410 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	55,550,399 - 55,817,402 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	59,039,717 - 59,325,925 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	59,039,720 - 59,325,947 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	59,207,155 - 59,335,376 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	7	59,041,711 - 59,084,462 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	55,324,246 - 55,612,945 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	48,446,749 - 48,710,763 (+)	NCBI		Celera
RGSC_v3.1	7	55,344,975 - 55,633,672 (+)	NCBI
Cytogenetic Map	7	q22	NCBI

PTPRR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	70,638,073 - 70,920,738 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	70,638,073 - 70,920,738 (-)	Ensembl			hg38	GRCh38
GRCh37	12	71,031,853 - 71,314,518 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	69,318,129 - 69,600,853 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	69,318,128 - 69,434,632	NCBI
Celera	12	70,695,535 - 70,977,822 (-)	NCBI		Celera
Cytogenetic Map	12	q15	NCBI
HuRef	12	68,081,248 - 68,364,028 (-)	NCBI		HuRef
CHM1_1	12	71,001,121 - 71,283,977 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	70,617,477 - 70,900,236 (-)	NCBI		T2T-CHM13v2.0

Ptprr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	115,854,093 - 116,110,837 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	115,854,118 - 116,110,837 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	116,018,188 - 116,274,932 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	116,018,213 - 116,274,932 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	115,455,419 - 115,711,985 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	115,422,509 - 115,679,039 (+)	NCBI		MGSCv36	mm8
Celera	10	117,959,423 - 118,215,461 (+)	NCBI		Celera
Cytogenetic Map	10	D2	NCBI
cM Map	10	64.01	NCBI

Ptprr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	10,767,507 - 11,026,914 (-)	Ensembl
ChiLan1.0	NW_004955405	10,767,548 - 11,133,695 (-)	NCBI	ChiLan1.0	ChiLan1.0

PTPRR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	78,653,652 - 78,936,078 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	78,650,051 - 78,932,477 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	68,148,200 - 68,430,618 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	70,915,951 - 71,197,146 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	70,915,951 - 71,196,732 (-)	Ensembl			panPan2	panpan1.1

PTPRR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	12,385,121 - 12,618,438 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	12,385,107 - 12,594,004 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	12,324,091 - 12,557,686 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	12,517,368 - 12,751,240 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	12,517,368 - 12,751,216 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	12,382,959 - 12,616,783 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	12,630,054 - 12,863,956 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	12,754,267 - 12,988,172 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ptprr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	45,732,053 - 45,841,891 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936545	8,268,218 - 8,377,169 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936545	8,268,227 - 8,377,427 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTPRR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	34,794,977 - 35,047,818 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	34,794,970 - 35,048,550 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	37,346,846 - 37,511,950 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PTPRR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	66,222,495 - 66,496,247 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	66,223,605 - 66,353,700 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	179,171,480 - 179,454,986 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptprr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624750	26,906,871 - 27,188,249 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624750	26,907,292 - 27,188,129 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ptprr
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	194,183,355 - 194,432,708 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ptprr
1474 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	642
Count of miRNA genes:	276
Interacting mature miRNAs:	359
Transcripts:	ENSRNOT00000006401
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	23807606	68807606	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	45113903	90113903	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	10517086	62346019	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	26638057	71638057	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	51700643	96700643	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	24179478	86817926	Rat
10059605	Kidm47	Kidney mass QTL 47	2.91	0.05	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	49137999	67614020	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	10112916	60150541	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	39845902	84845902	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	9460877	54460877	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	32998702	77998702	Rat
2317059	Aia15	Adjuvant induced arthritis QTL 15	2.46		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	49682832	63890004	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	36178764	81178764	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	48475049	93475049	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	36178764	81178764	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2303629	Vencon3	Ventilatory control QTL 3	7.25		respiration trait (VT:0001943)	respiration rate (CMO:0000289)	7	42996226	58678836	Rat
70190	Mcs6	Mammary carcinoma susceptibility QTL 6	2.29		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	28624575	65788017	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	21541977	86817926	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
1300138	Hrtrt9	Heart rate QTL 9	4.72		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	10498820	55498820	Rat
738033	Anxrr6	Anxiety related response QTL 6	4.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	7	17460447	62460447	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
2303582	Gluco53	Glucose level QTL 53	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	7	48603087	93603087	Rat
70207	Niddm31	Non-insulin dependent diabetes mellitus QTL 31	3.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	20057232	65057232	Rat
61439	Cia8	Collagen induced arthritis QTL 8	5.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	7	27182914	72182914	Rat

Markers in Region

D7Got237

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	51,685,053 - 51,685,209 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	59,060,586 - 59,060,741	NCBI	Rnor6.0
Rnor_5.0	7	59,063,595 - 59,063,750	UniSTS	Rnor5.0
RGSC_v3.4	7	55,364,167 - 55,364,322	UniSTS	RGSC3.4
Celera	7	48,468,205 - 48,468,360	UniSTS
Cytogenetic Map	7	q22	UniSTS

RH131513

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	51,929,395 - 51,929,575 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	59,325,716 - 59,325,895	NCBI	Rnor6.0
Rnor_5.0	7	59,335,167 - 59,335,346	UniSTS	Rnor5.0
RGSC_v3.4	7	55,612,736 - 55,612,915	UniSTS	RGSC3.4
Celera	7	48,710,554 - 48,710,733	UniSTS
RH 3.4 Map	7	476.0	UniSTS
Cytogenetic Map	7	q22	UniSTS

AU048245

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	53,667,399 - 53,667,568 (+)	Marker Load Pipeline
mRatBN7.2	7	51,781,357 - 51,781,526 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	62,386,196 - 62,386,364	NCBI	Rnor6.0
Rnor_5.0	7	62,372,783 - 62,372,951	UniSTS	Rnor5.0
RGSC_v3.4	7	55,461,824 - 55,461,992	UniSTS	RGSC3.4
Celera	7	48,564,539 - 48,564,707	UniSTS
Cytogenetic Map	7	q22	UniSTS

D7Uwm24

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	51,685,029 - 51,685,285 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	59,060,562 - 59,060,817	NCBI	Rnor6.0
Rnor_5.0	7	59,063,571 - 59,063,826	UniSTS	Rnor5.0
Celera	7	48,468,181 - 48,468,436	UniSTS
Cytogenetic Map	7	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	152	89	88	57	30	57	6	292	130	11	127	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001113390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_053594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC089186	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D38292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D64050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U14914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006401 ⟹ ENSRNOP00000006401

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	53,548,629 - 53,815,629 (+)	Ensembl
mRatBN7.2 Ensembl	7	51,662,595 - 51,929,602 (+)	Ensembl
Rnor_6.0 Ensembl	7	59,039,720 - 59,325,947 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085073 ⟹ ENSRNOP00000070648

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	53,686,237 - 53,815,629 (+)	Ensembl
mRatBN7.2 Ensembl	7	51,800,156 - 51,929,603 (+)	Ensembl
Rnor_6.0 Ensembl	7	59,200,918 - 59,325,922 (+)	Ensembl

RefSeq Acc Id:

NM_001113390 ⟹ NP_001106861

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	53,686,239 - 53,815,632 (+)	NCBI
mRatBN7.2	7	51,800,199 - 51,929,605 (+)	NCBI
Rnor_6.0	7	59,200,941 - 59,325,925 (+)	NCBI
Rnor_5.0	7	59,207,155 - 59,335,376 (+)	NCBI
RGSC_v3.4	7	55,324,246 - 55,612,945 (+)	RGD
Celera	7	48,583,357 - 48,710,763 (+)	NCBI

Sequence:

show sequence

TAGCAGTCGGCTAGCTCCAAGTGACTAAACAAAGCTTCAGCTCGCAGGCTTTCTGATTAGTCCA
ACTAGCCATGGTGAGGGAGTAACAAGAAGAACACAAATGGAAGCCGGATGCATCGCAACACTCG
ACACTGCAAATGGATATAGACAAGCTGAACATAACCTTGCTTCGGATCTTCCGCCAAGGAGTAG
CTGCAGCCCTGGGACTCTTACCTCAGCAAGTACACATCAACCGCCTCATTGAAAAGAAGAGCCA
GATTGAGTTGTTTGTGTCTCCCGGAAACCGGAAACCAGGAGAGCCGCAGGCCCTGCAGGCTGAG
GAAGTACTGCGTTCCCTTAATGTGGATGTTTTGCGTCAGAGTTTACCACAGTTTGGAATTATAG
ACGTCTCCCCTGAGAAAAATGTTTTACAAGGGCAGCATGAAGCGGACAAGATCTGGAGCAAAGA
AGGCTTTTACGCCGTCGTCATCTTCCTCAGCATCTTTATCATTATAGTAACCTGTTTGATGATC
ATTTATAGGTTAAAAGAAAGGCTTCAGCTTTCCTTACGACAAGATAAAGAGAAAAACCAGGAGA
TCCACCTATCGCCCATTGCACTCCAGCAAGCACAATCGGAGGCCAAGGCAGCCCACAGCATGGT
CCAGCCCGACCAGGCGCCAAAGGTGCTGAATGTTGTTGTGGACCCTCAAGGCCAATGCACTCCT
GAGATTCGAAACACCGCCTCCACTTCTGTCTGCCCTTCTCCCTTCAGGATGAAGCCCATAGGAC
TCCAGGAGCGACGAGGTTCCAATGTATCTCTTACACTGGACATGAGTAGCCTGGGCAACGTGGA
ACCCTTTGTGGCCGTCTCCACCCCCCGGGAGAAGGTAGCCATGGAGTACCTGCAGTCAGCCAGC
CGAGTTCTCACAAGGCCACAGCTGAGGGACGTCGTGGCAAGTTCCCACCTGCTTCAAAGTGAAT
TCATGGAAATACCAATGAACTTTGTGGATCCCAAAGAAATTGATATTCCACGTCATGGAACTAA
AAATCGTTATAAGACCATTTTGCCAAATCCCCTCAGCAGGGTGTGCTTAAGACCAAAAAATATA
ACTGACCCATTGAGTACTTACATCAATGCTAATTACATTCGGGGCTACAGTGGCAAGGAGAAAG
CCTTCATTGCCACACAGGGCCCCATGATCAACACTGTGAATGACTTCTGGCAGATGGTTTGGCA
AGAAGACAGTCCTGTGATTGTTATGATCACGAAACTCAAAGAGAAAAATGAGAAATGTGTGCTC
TACTGGCCAGAAAAGAGAGGGATTTACGGCAAGGTTGAGGTTCTGGTCATCGGTGTCAATGAAT
GTGATAACTACACCATCCGCAACCTCGTCTTGAAGCGAGGAAGTCACACCCAACATGTGAAGCA
TTACTGGTACACTTCATGGCCCGATCACAAGACTCCAGACAGTGCCCAGCCCCTTCTGCAGCTC
ATGCTGGACGTAGAGGAAGACAGACTGGCCTCTGAAGGCCGAGGGCCTGTGGTTGTCCACTGCA
GTGCAGGGATTGGGAGAACCGGATGTTTCATCGCTACATCCATTGGCTGTCAACAGTTGAAAGA
AGAAGGAGTCGTAGATGCACTAAGTATCGTCTGCCAGCTTCGTGTAGACAGGGGTGGAATGGTC
CAAACCAGTGAGCAGTATGAATTTGTGCACCACGCTCTGTGCCTGTTCGAGAGCAGACTTTCGC
CAGAAACGGTCCAGTGACTCTGAAGATCTACCAGAGCGTCAATCTATCACGGGTGATTCGTCAA
GTTACCTACTGAGGGCTCCGAGAAGGAGCTCCCCACGATGGATGAGGAGGCTCTAAAGCCAGCC
TGAGGCGTGGATTGTGGAAGCTATGGTAACTTGAAAGATTGCCACCTTTGTGTATAGGACTGTG
TTCTAGGCATCCCCCTAGTTACTCCGAAGGACCTGTGCTGATGGAGGTGTGACAGTCCTCATGC
AGCCTGAGGAGGATTCTGTTTTGTCTGTGTCGACTCTCACACAGAACCTGTATGTGTAATATTC
AGAGTCTGTGCTTATGGTGACTGGAGGAGCTGCGGAAGATATCGTTATCCTGTGTTAGATGCTT
TAATGTTCACAAAGCCTGTCTTGTGACTGGACTGTCAGCTGTTCAACTGTTCCTGTATTAAGTG
CTATTACCTATCTCAGTTACCAGAGTCTTGCTGCTAAAGTTGCAAGTGACCGACAATGGATTTT
TAACCATGACGTTTTTTGTTTTTGAAAAAAAAAAATCAAAGGCAGTAACTATTTTATATGGAGA
TGTGTCTTGATTATCTCTAATAAGTGTGTATTTATAGTATCTCCTATGGATCAATTACAGAGCA
CAATGATTGTCACTGGATATATATGTATATGTACATTACAGGTATATGTACGCATATATATTCT
ATTATTAAGCATAGAGGTAGCTCCTGTTTTACAACTCTAACTACTATATTTCTACATTGTGACT
TGTTTTACTTTAAAAGGGGATAAACAAATTTATAGTAACTATAAAGTATCAATAATTTTAAATA
CTCATCTCTCTTTTACTAAGAAGGGATTTTTGAATATAGTGTCTACTTGGTTTCTCTCTCCCAG
TAAGAAGCAGGTGCCTTTGGGGATGCTCCAACCTGTTTCATCCCCAAAAGTTTTTCTGAGGACA
CCGTCATGCACGCATGACCTTAAATTTCTAAAAGGTTTTCTTCCTCAAGAGACCAATGAAGGCA
AGATAACCGCACTCAGCAAACATGAGATGTTCTGCTCAGATGTGAATTTTCAATGCAGCAAAGT
TGACTTTCGTACTCCCAATAAATGACTCTTAACAGCAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_053594 ⟹ NP_446046

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	53,548,642 - 53,815,632 (+)	NCBI
mRatBN7.2	7	51,662,595 - 51,929,605 (+)	NCBI
Rnor_6.0	7	59,039,717 - 59,325,925 (+)	NCBI
Rnor_5.0	7	59,041,711 - 59,084,462 (+)	NCBI
Rnor_5.0	7	59,207,155 - 59,335,376 (+)	NCBI
RGSC_v3.4	7	55,324,246 - 55,612,945 (+)	RGD
Celera	7	48,446,749 - 48,710,763 (+)	RGD

Sequence:

show sequence

GAGCTCGTTCCCCTCGCAGCCTCAGCTAAGACCCGGAGAGGTGGAATTTCGATTTGAAACTCCC
TAGCCAGGGCCGGGGCTGGGCATGCTCAGTGCCTCGGTGTATCGGGCTGCTGCTAGCTGCACAG
GCAGCAGAGGCGCTGCCTGGCTTGGAAGCTGGCACAAGAGTCCACCCCACTGTCACCACCGACT
GCGGGCTTCAGGAAGGCCAAACACTCACCTCCTCTGAGCGCTTTACACCCACCAACCTCGAGTC
CCCATCTCCCGCAGCATCCTACTCTCCCGTCTCCCCATCCCTTAGGGAGACGAAGCCAGTGCTC
GGTTCTGTAGGCACGCCACAGACTGCTCTGTGAACCCCAGCGGAGGACCCTGTCATCGGATGCC
TCGGGATCAAAGGACTCTTGGCAGTGTTTCTCTCAAATAGCACTTTGCCTGGAGTGGGATTGCG
GTGGAGTTTCTCCCCCGCCCCTCAATGCACACACTATGAGGAGAGCGGTCGGTTTCCCTGCACT
GTGCCTGCTTCTTAATCTTCACGCTGCAGGGTGTTTTTCCAGGAACAATGACCACTTTTTGGCT
ATTCGTCAAAAGAAGAGTTGGAAACCCATGTTCATTTATGACCATTCCCAAGACATTAAGAAGA
GCCTGGATATCGCTCAAGAGGCATATAAACACAACTACCCCGCCCCCTCAGAAGTTCAAATAAG
CAAACGTCACCAGATCGTTGATTCAGCATTTCCTAGACCTGCATATGACCCATCTCTTAATCTG
TTGGCTGCATCTGGTCAAGACCTCGAAATAGAAAATCTCCCAATTCCAGCAGCAAATGTGATTG
TGGTGACACTGCAAATGGATATAGACAAGCTGAACATAACCTTGCTTCGGATCTTCCGCCAAGG
AGTAGCTGCAGCCCTGGGACTCTTACCTCAGCAAGTACACATCAACCGCCTCATTGAAAAGAAG
AGCCAGATTGAGTTGTTTGTGTCTCCCGGAAACCGGAAACCAGGAGAGCCGCAGGCCCTGCAGG
CTGAGGAAGTACTGCGTTCCCTTAATGTGGATGTTTTGCGTCAGAGTTTACCACAGTTTGGAAT
TATAGACGTCTCCCCTGAGAAAAATGTTTTACAAGGGCAGCATGAAGCGGACAAGATCTGGAGC
AAAGAAGGCTTTTACGCCGTCGTCATCTTCCTCAGCATCTTTATCATTATAGTAACCTGTTTGA
TGATCATTTATAGGTTAAAAGAAAGGCTTCAGCTTTCCTTACGACAAGATAAAGAGAAAAACCA
GGAGATCCACCTATCGCCCATTGCACTCCAGCAAGCACAATCGGAGGCCAAGGCAGCCCACAGC
ATGGTCCAGCCCGACCAGGCGCCAAAGGTGCTGAATGTTGTTGTGGACCCTCAAGGCCAATGCA
CTCCTGAGATTCGAAACACCGCCTCCACTTCTGTCTGCCCTTCTCCCTTCAGGATGAAGCCCAT
AGGACTCCAGGAGCGACGAGGTTCCAATGTATCTCTTACACTGGACATGAGTAGCCTGGGCAAC
GTGGAACCCTTTGTGGCCGTCTCCACCCCCCGGGAGAAGGTAGCCATGGAGTACCTGCAGTCAG
CCAGCCGAGTTCTCACAAGGCCACAGCTGAGGGACGTCGTGGCAAGTTCCCACCTGCTTCAAAG
TGAATTCATGGAAATACCAATGAACTTTGTGGATCCCAAAGAAATTGATATTCCACGTCATGGA
ACTAAAAATCGTTATAAGACCATTTTGCCAAATCCCCTCAGCAGGGTGTGCTTAAGACCAAAAA
ATATAACTGACCCATTGAGTACTTACATCAATGCTAATTACATTCGGGGCTACAGTGGCAAGGA
GAAAGCCTTCATTGCCACACAGGGCCCCATGATCAACACTGTGAATGACTTCTGGCAGATGGTT
TGGCAAGAAGACAGTCCTGTGATTGTTATGATCACGAAACTCAAAGAGAAAAATGAGAAATGTG
TGCTCTACTGGCCAGAAAAGAGAGGGATTTACGGCAAGGTTGAGGTTCTGGTCATCGGTGTCAA
TGAATGTGATAACTACACCATCCGCAACCTCGTCTTGAAGCGAGGAAGTCACACCCAACATGTG
AAGCATTACTGGTACACTTCATGGCCCGATCACAAGACTCCAGACAGTGCCCAGCCCCTTCTGC
AGCTCATGCTGGACGTAGAGGAAGACAGACTGGCCTCTGAAGGCCGAGGGCCTGTGGTTGTCCA
CTGCAGTGCAGGGATTGGGAGAACCGGATGTTTCATCGCTACATCCATTGGCTGTCAACAGTTG
AAAGAAGAAGGAGTCGTAGATGCACTAAGTATCGTCTGCCAGCTTCGTGTAGACAGGGGTGGAA
TGGTCCAAACCAGTGAGCAGTATGAATTTGTGCACCACGCTCTGTGCCTGTTCGAGAGCAGACT
TTCGCCAGAAACGGTCCAGTGACTCTGAAGATCTACCAGAGCGTCAATCTATCACGGGTGATTC
GTCAAGTTACCTACTGAGGGCTCCGAGAAGGAGCTCCCCACGATGGATGAGGAGGCTCTAAAGC
CAGCCTGAGGCGTGGATTGTGGAAGCTATGGTAACTTGAAAGATTGCCACCTTTGTGTATAGGA
CTGTGTTCTAGGCATCCCCCTAGTTACTCCGAAGGACCTGTGCTGATGGAGGTGTGACAGTCCT
CATGCAGCCTGAGGAGGATTCTGTTTTGTCTGTGTCGACTCTCACACAGAACCTGTATGTGTAA
TATTCAGAGTCTGTGCTTATGGTGACTGGAGGAGCTGCGGAAGATATCGTTATCCTGTGTTAGA
TGCTTTAATGTTCACAAAGCCTGTCTTGTGACTGGACTGTCAGCTGTTCAACTGTTCCTGTATT
AAGTGCTATTACCTATCTCAGTTACCAGAGTCTTGCTGCTAAAGTTGCAAGTGACCGACAATGG
ATTTTTAACCATGACGTTTTTTGTTTTTGAAAAAAAAAAATCAAAGGCAGTAACTATTTTATAT
GGAGATGTGTCTTGATTATCTCTAATAAGTGTGTATTTATAGTATCTCCTATGGATCAATTACA
GAGCACAATGATTGTCACTGGATATATATGTATATGTACATTACAGGTATATGTACGCATATAT
ATTCTATTATTAAGCATAGAGGTAGCTCCTGTTTTACAACTCTAACTACTATATTTCTACATTG
TGACTTGTTTTACTTTAAAAGGGGATAAACAAATTTATAGTAACTATAAAGTATCAATAATTTT
AAATACTCATCTCTCTTTTACTAAGAAGGGATTTTTGAATATAGTGTCTACTTGGTTTCTCTCT
CCCAGTAAGAAGCAGGTGCCTTTGGGGATGCTCCAACCTGTTTCATCCCCAAAAGTTTTTCTGA
GGACACCGTCATGCACGCATGACCTTAAATTTCTAAAAGGTTTTCTTCCTCAAGAGACCAATGA
AGGCAAGATAACCGCACTCAGCAAACATGAGATGTTCTGCTCAGATGTGAATTTTCAATGCAGC
AAAGTTGACTTTCGTACTCCCAATAAATGACTCTTAACAGCAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063264355 ⟹ XP_063120425

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	53,548,611 - 53,815,632 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001106861	(Get FASTA)	NCBI Sequence Viewer
	NP_446046	(Get FASTA)	NCBI Sequence Viewer
	XP_063120425	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA64485	(Get FASTA)	NCBI Sequence Viewer
	AAH89186	(Get FASTA)	NCBI Sequence Viewer
	BAA07414	(Get FASTA)	NCBI Sequence Viewer
	BAA19530	(Get FASTA)	NCBI Sequence Viewer
	EDM16674	(Get FASTA)	NCBI Sequence Viewer
	EDM16675	(Get FASTA)	NCBI Sequence Viewer
	EDM16676	(Get FASTA)	NCBI Sequence Viewer
	EDM16677	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006401
	ENSRNOP00000070648
GenBank Protein	O08617	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_446046 ⟸ NM_053594
- Peptide Label:	isoform 1 precursor
- UniProtKB:	Q63419 (UniProtKB/Swiss-Prot), Q62695 (UniProtKB/Swiss-Prot), O08617 (UniProtKB/Swiss-Prot), G3V6L5 (UniProtKB/TrEMBL), A6IGM0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRRAVGFPALCLLLNLHAAGCFSRNNDHFLAIRQKKSWKPMFIYDHSQDIKKSLDIAQEAYKHN YPAPSEVQISKRHQIVDSAFPRPAYDPSLNLLAASGQDLEIENLPIPAANVIVVTLQMDIDKLN ITLLRIFRQGVAAALGLLPQQVHINRLIEKKSQIELFVSPGNRKPGEPQALQAEEVLRSLNVDV LRQSLPQFGIIDVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFIIIVTCLMIIYRLKERLQL SLRQDKEKNQEIHLSPIALQQAQSEAKAAHSMVQPDQAPKVLNVVVDPQGQCTPEIRNTASTSV CPSPFRMKPIGLQERRGSNVSLTLDMSSLGNVEPFVAVSTPREKVAMEYLQSASRVLTRPQLRD VVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNITDPLSTYINA NYIRGYSGKEKAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYG KVEVLVIGVNECDNYTIRNLVLKRGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLA SEGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRVDRGGMVQTSEQYEFVH HALCLFESRLSPETVQ hide sequence

RefSeq Acc Id:	NP_001106861 ⟸ NM_001113390
- Peptide Label:	isoform 2
- UniProtKB:	A0A0G2JYG7 (UniProtKB/TrEMBL), A6IGM2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDIDKLNITLLRIFRQGVAAALGLLPQQVHINRLIEKKSQIELFVSPGNRKPGEPQALQAEEVL RSLNVDVLRQSLPQFGIIDVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFIIIVTCLMIIYR LKERLQLSLRQDKEKNQEIHLSPIALQQAQSEAKAAHSMVQPDQAPKVLNVVVDPQGQCTPEIR NTASTSVCPSPFRMKPIGLQERRGSNVSLTLDMSSLGNVEPFVAVSTPREKVAMEYLQSASRVL TRPQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNITDP LSTYINANYIRGYSGKEKAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWP EKRGIYGKVEVLVIGVNECDNYTIRNLVLKRGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLD VEEDRLASEGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRVDRGGMVQTS EQYEFVHHALCLFESRLSPETVQ hide sequence

Ensembl Acc Id:

ENSRNOP00000006401 ⟸ ENSRNOT00000006401

Ensembl Acc Id:

ENSRNOP00000070648 ⟸ ENSRNOT00000085073

RefSeq Acc Id:	XP_063120425 ⟸ XM_063264355
- Peptide Label:	isoform X1
- UniProtKB:	Q63419 (UniProtKB/Swiss-Prot), Q62695 (UniProtKB/Swiss-Prot), O08617 (UniProtKB/Swiss-Prot)

Protein Domains

Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O08617-F1-model_v2	AlphaFold	O08617	1-656	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695204

Promoter ID:

EPDNEW_R5726

Type:

multiple initiation site

Name:

Ptprr_1

Description:

protein tyrosine phosphatase, receptor type, R

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	59,039,813 - 59,039,873	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620780	AgrOrtholog
BioCyc Gene	G2FUF-34044	BioCyc
Ensembl Genes	ENSRNOG00000004483	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000006401	ENTREZGENE
	ENSRNOT00000085073	ENTREZGENE
Gene3D-CATH	3.90.190.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7315399	IMAGE-MGC_LOAD
InterPro	Prot-tyrosine_phosphatase-like	UniProtKB/Swiss-Prot
	PTPase_domain	UniProtKB/Swiss-Prot
	Tyr_Pase_AS	UniProtKB/Swiss-Prot
	Tyr_Pase_cat	UniProtKB/Swiss-Prot
	Tyr_Pase_KIM-con	UniProtKB/Swiss-Prot
	Tyr_Pase_rcpt_R/non-rcpt_5	UniProtKB/Swiss-Prot
	TYR_PHOSPHATASE_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:94202	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105367	IMAGE-MGC_LOAD
NCBI Gene	94202	ENTREZGENE
PANTHER	PTHR46198	UniProtKB/Swiss-Prot
	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE R	UniProtKB/Swiss-Prot
Pfam	Y_phosphatase	UniProtKB/Swiss-Prot
PhenoGen	Ptprr	PhenoGen
PIRSF	PTPRR	UniProtKB/Swiss-Prot
PRINTS	KIMPTPASE	UniProtKB/Swiss-Prot
	PRTYPHPHTASE	UniProtKB/Swiss-Prot
PROSITE	TYR_PHOSPHATASE_1	UniProtKB/Swiss-Prot
	TYR_PHOSPHATASE_2	UniProtKB/Swiss-Prot
	TYR_PHOSPHATASE_PTP	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000004483	RatGTEx
SMART	PTPc	UniProtKB/Swiss-Prot
	PTPc_motif	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52799	UniProtKB/Swiss-Prot
UniProt	A0A0G2JYG7	ENTREZGENE, UniProtKB/TrEMBL
	A6IGM0	ENTREZGENE, UniProtKB/TrEMBL
	A6IGM2	ENTREZGENE, UniProtKB/TrEMBL
	A6IGM3_RAT	UniProtKB/TrEMBL
	A6IGM4_RAT	UniProtKB/TrEMBL
	G3V6L5	ENTREZGENE, UniProtKB/TrEMBL
	O08617	ENTREZGENE, UniProtKB/Swiss-Prot
	Q5FWV8_RAT	UniProtKB/TrEMBL
	Q62695	ENTREZGENE
	Q63419	ENTREZGENE
UniProt Secondary	Q62695	UniProtKB/Swiss-Prot
	Q63419	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Ptprr	protein tyrosine phosphatase, receptor type, R			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Ptprr	protein tyrosine phosphatase, receptor type, R			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_regulation	mRNA expression of the 3.0 kb transcript is induced by nerve growth factor	729713
gene_transcript	contains 1.5, 2.6, and 3.0 kb mRNA transcripts	729713

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)