Ip6k2 (inositol hexakisphosphate kinase 2) - Rat Genome Database

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Gene: Ip6k2 (inositol hexakisphosphate kinase 2) Rattus norvegicus
Analyze
Symbol: Ip6k2
Name: inositol hexakisphosphate kinase 2
RGD ID: 620529
Description: Predicted to enable flavonoid binding activity and inositol hexakisphosphate 5-kinase activity. Involved in phosphate ion transport. Predicted to be located in cell junction; fibrillar center; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human IP6K2 (inositol hexakisphosphate kinase 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ihpk2; inositol hexaphosphate kinase 2; InsP6 kinase 2; P(i)-uptake stimulator; Pius
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,362,154 - 118,388,668 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,362,795 - 118,388,667 (+)EnsemblGRCr8
mRatBN7.28109,483,843 - 109,510,172 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,484,310 - 109,510,166 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,103,519 - 115,127,769 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,302,698 - 113,326,948 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,145,495 - 111,169,746 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd8119,249,969 - 119,275,662 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive8121,354,906 - 121,380,600 (+)NCBILyon_Normotensive
Lyon_Hypertensive8119,844,626 - 119,870,320 (+)NCBILyon_Hypertensive
F344_StmMcwi8111,246,710 - 111,272,400 (+)NCBIF344_StmMcwi
Rnor_6.08117,574,136 - 117,599,849 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,574,161 - 117,599,848 (+)Ensemblrn6Rnor6.0
Rnor_5.08116,921,132 - 116,944,750 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,836,756 - 113,861,895 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,780,684 - 108,804,293 (+)NCBICelera
RGSC_v3.18113,870,909 - 113,881,351 (+)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
clotrimazole  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
erythromycin estolate  (EXP)
estriol  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gallic acid  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
leflunomide  (EXP)
levofloxacin  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
Methylazoxymethanol acetate  (EXP)
N-nitrosodiethylamine  (EXP)
okadaic acid  (ISO)
orphenadrine  (EXP)
oxycodone  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl caffeate  (EXP)
phenformin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
ritodrine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP,ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
fibrillar center  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Regulation of intestinal Na+-dependent phosphate co-transporters by a low-phosphate diet and 1,25-dihydroxyvitamin D3. Katai K, etal., Biochem J 1999 Nov 1;343 Pt 3:705-12.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10574768   PMID:11337497   PMID:11502751   PMID:12477932   PMID:30624931  


Genomics

Comparative Map Data
Ip6k2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,362,154 - 118,388,668 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,362,795 - 118,388,667 (+)EnsemblGRCr8
mRatBN7.28109,483,843 - 109,510,172 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,484,310 - 109,510,166 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8115,103,519 - 115,127,769 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,302,698 - 113,326,948 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,145,495 - 111,169,746 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd8119,249,969 - 119,275,662 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive8121,354,906 - 121,380,600 (+)NCBILyon_Normotensive
Lyon_Hypertensive8119,844,626 - 119,870,320 (+)NCBILyon_Hypertensive
F344_StmMcwi8111,246,710 - 111,272,400 (+)NCBIF344_StmMcwi
Rnor_6.08117,574,136 - 117,599,849 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,574,161 - 117,599,848 (+)Ensemblrn6Rnor6.0
Rnor_5.08116,921,132 - 116,944,750 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,836,756 - 113,861,895 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,780,684 - 108,804,293 (+)NCBICelera
RGSC_v3.18113,870,909 - 113,881,351 (+)NCBI
Cytogenetic Map8q32NCBI
IP6K2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,688,003 - 48,717,221 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,688,003 - 48,740,353 (-)Ensemblhg38GRCh38
GRCh37348,725,436 - 48,754,654 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,700,440 - 48,729,710 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34348,700,440 - 48,729,710NCBI
Celera348,681,373 - 48,710,646 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,783,857 - 48,813,325 (-)NCBIHuRef
CHM1_1348,677,527 - 48,706,810 (-)NCBICHM1_1
T2T-CHM13v2.0348,716,988 - 48,746,201 (-)NCBIT2T-CHM13v2.0
Ip6k2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,660,928 - 108,683,532 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,660,995 - 108,683,536 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389108,783,764 - 108,806,333 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,783,796 - 108,806,337 (+)Ensemblmm10GRCm38
MGSCv379108,698,325 - 108,708,664 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369108,653,217 - 108,663,556 (+)NCBIMGSCv36mm8
Celera9108,403,128 - 108,413,468 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.63NCBI
Ip6k2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532766,577 - 794,409 (-)Ensembl
ChiLan1.0NW_004955532766,577 - 794,461 (-)NCBIChiLan1.0ChiLan1.0
IP6K2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,662,753 - 48,693,498 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,667,521 - 48,698,266 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,608,902 - 48,638,185 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,690,486 - 49,719,811 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,690,486 - 49,719,798 (-)EnsemblpanPan2panpan1.1
IP6K2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,403,260 - 40,437,863 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,427,083 - 40,437,804 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2040,320,579 - 40,355,092 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02040,888,751 - 40,923,377 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,888,832 - 40,923,377 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,126,293 - 40,160,881 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,530,369 - 40,565,188 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,812,078 - 40,846,684 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ip6k2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,726,780 - 63,755,149 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529486,879 - 515,674 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936529487,277 - 515,614 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IP6K2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,379,521 - 31,406,911 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11331,379,516 - 31,406,989 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,646,759 - 34,655,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IP6K2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,097,730 - 10,121,325 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,097,746 - 10,121,840 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041156,967,477 - 156,992,136 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ip6k2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,697,098 - 2,734,636 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247302,697,098 - 2,734,198 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ip6k2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18100,112,897 - 100,137,899 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ip6k2
248 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:47
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000027584
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH144690  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,497,031 - 109,497,247 (+)MAPPERmRatBN7.2
Rnor_6.08117,586,900 - 117,587,115NCBIRnor6.0
Rnor_5.08116,932,067 - 116,932,282UniSTSRnor5.0
RGSC_v3.48113,848,833 - 113,849,048UniSTSRGSC3.4
Celera8108,791,530 - 108,791,745UniSTS
RH 3.4 Map81115.3UniSTS
Cytogenetic Map8q32UniSTS
UniSTS:532317  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,509,564 - 109,509,986 (+)MAPPERmRatBN7.2
Rnor_6.08117,599,243 - 117,599,664NCBIRnor6.0
Rnor_5.08116,944,144 - 116,944,565UniSTSRnor5.0
Celera8108,803,687 - 108,804,108UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027584   ⟹   ENSRNOP00000027584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,378,028 - 118,388,667 (+)Ensembl
mRatBN7.2 Ensembl8109,499,531 - 109,510,166 (+)Ensembl
Rnor_6.0 Ensembl8117,576,788 - 117,599,848 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077078   ⟹   ENSRNOP00000071056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,364,677 - 118,388,667 (+)Ensembl
mRatBN7.2 Ensembl8109,484,310 - 109,510,166 (+)Ensembl
Rnor_6.0 Ensembl8117,574,161 - 117,599,843 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099109   ⟹   ENSRNOP00000092455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,362,795 - 118,379,064 (+)Ensembl
mRatBN7.2 Ensembl8109,499,531 - 109,500,567 (+)Ensembl
RefSeq Acc Id: NM_001431589   ⟹   NP_001418518
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd8119,249,969 - 119,275,662 (+)NCBI
Lyon_Normotensive8121,354,906 - 121,380,600 (+)NCBI
Lyon_Hypertensive8119,844,626 - 119,870,320 (+)NCBI
F344_StmMcwi8111,246,710 - 111,272,400 (+)NCBI
RefSeq Acc Id: NM_021660   ⟹   NP_067692
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,364,677 - 118,388,668 (+)NCBI
mRatBN7.28109,486,179 - 109,510,172 (+)NCBI
Dahl_SR_JrHsd8119,251,798 - 119,275,662 (+)NCBI
Lyon_Normotensive8121,356,735 - 121,380,600 (+)NCBI
Lyon_Hypertensive8119,846,455 - 119,870,320 (+)NCBI
F344_StmMcwi8111,248,539 - 111,272,400 (+)NCBI
Rnor_6.08117,576,048 - 117,599,849 (+)NCBI
Rnor_5.08116,921,132 - 116,944,750 (+)NCBI
RGSC_v3.48113,836,756 - 113,861,895 (+)RGD
Celera8108,780,684 - 108,804,293 (+)RGD
Sequence:
RefSeq Acc Id: XM_008766564   ⟹   XP_008764786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,362,645 - 118,388,668 (+)NCBI
mRatBN7.28109,484,212 - 109,510,172 (+)NCBI
Rnor_6.08117,574,137 - 117,599,849 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039082043   ⟹   XP_038937971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,364,824 - 118,388,668 (+)NCBI
mRatBN7.28109,486,926 - 109,510,172 (+)NCBI
RefSeq Acc Id: XM_039082044   ⟹   XP_038937972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,362,450 - 118,379,799 (+)NCBI
mRatBN7.28109,483,843 - 109,501,302 (+)NCBI
RefSeq Acc Id: XM_039082045   ⟹   XP_038937973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,362,154 - 118,379,799 (+)NCBI
mRatBN7.28109,483,847 - 109,501,302 (+)NCBI
RefSeq Acc Id: XM_063266056   ⟹   XP_063122126
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,363,096 - 118,388,668 (+)NCBI
RefSeq Acc Id: XM_063266057   ⟹   XP_063122127
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,362,710 - 118,388,668 (+)NCBI
RefSeq Acc Id: XM_063266058   ⟹   XP_063122128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,378,110 - 118,388,668 (+)NCBI
RefSeq Acc Id: NP_067692   ⟸   NM_021660
- UniProtKB: Q5XIU6 (UniProtKB/Swiss-Prot),   Q9R0U1 (UniProtKB/Swiss-Prot),   A6I382 (UniProtKB/TrEMBL),   A0A8L2UKG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008764786   ⟸   XM_008766564
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000071056   ⟸   ENSRNOT00000077078
Ensembl Acc Id: ENSRNOP00000027584   ⟸   ENSRNOT00000027584
RefSeq Acc Id: XP_038937972   ⟸   XM_039082044
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038937973   ⟸   XM_039082045
- Peptide Label: isoform X4
- UniProtKB: A6I383 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937971   ⟸   XM_039082043
- Peptide Label: isoform X1
- UniProtKB: Q9R0U1 (UniProtKB/Swiss-Prot),   Q5XIU6 (UniProtKB/Swiss-Prot),   A6I382 (UniProtKB/TrEMBL),   A0A8L2UKG6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092455   ⟸   ENSRNOT00000099109
RefSeq Acc Id: XP_063122127   ⟸   XM_063266057
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063122126   ⟸   XM_063266056
- Peptide Label: isoform X1
- UniProtKB: Q9R0U1 (UniProtKB/Swiss-Prot),   Q5XIU6 (UniProtKB/Swiss-Prot),   A6I382 (UniProtKB/TrEMBL),   A0A8L2UKG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122128   ⟸   XM_063266058
- Peptide Label: isoform X3
RefSeq Acc Id: NP_001418518   ⟸   NM_001431589

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9R0U1-F1-model_v2 AlphaFold Q9R0U1 1-425 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696324
Promoter ID:EPDNEW_R6840
Type:initiation region
Name:Ip6k2_1
Description:inositol hexakisphosphate kinase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,574,173 - 117,574,233EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620529 AgrOrtholog
BioCyc Gene G2FUF-29116 BioCyc
BioCyc Pathway PWY-6369 [inositol diphosphates biosynthesis] BioCyc
BioCyc Pathway Image PWY-6369 BioCyc
Ensembl Genes ENSRNOG00000020361 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027584 ENTREZGENE
  ENSRNOT00000077078 ENTREZGENE
  ENSRNOT00000077078.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.470.160 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7112777 IMAGE-MGC_LOAD
InterPro IPK UniProtKB/Swiss-Prot
  IPK_sf UniProtKB/Swiss-Prot
KEGG Report rno:59268 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93905 IMAGE-MGC_LOAD
NCBI Gene 59268 ENTREZGENE
PANTHER INOSITOL HEXAKISPHOSPHATE KINASE 2 UniProtKB/Swiss-Prot
  PTHR12400 UniProtKB/Swiss-Prot
Pfam IPK UniProtKB/Swiss-Prot
PhenoGen Ip6k2 PhenoGen
RatGTEx ENSRNOG00000020361 RatGTEx
Superfamily-SCOP SAICAR synthase-like UniProtKB/Swiss-Prot
UniProt A0A8I6AHJ9_RAT UniProtKB/TrEMBL
  A0A8L2UKG6 ENTREZGENE, UniProtKB/TrEMBL
  A6I382 ENTREZGENE, UniProtKB/TrEMBL
  A6I383 ENTREZGENE, UniProtKB/TrEMBL
  IP6K2_RAT UniProtKB/Swiss-Prot
  Q5XIU6 ENTREZGENE
  Q9R0U1 ENTREZGENE
UniProt Secondary Q5XIU6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-02-26 Ip6k2  inositol hexakisphosphate kinase 2  Ihpk2  inositol hexaphosphate kinase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Ihpk2  inositol hexaphosphate kinase 2  Pius  PiUS protein  Symbol and Name updated 1299863 APPROVED
2002-08-07 Pius  PiUS protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein 424 amino acids; 51 kDa 633655