Dpep1 (dipeptidase 1) - Rat Genome Database

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Gene: Dpep1 (dipeptidase 1) Rattus norvegicus
Analyze
Symbol: Dpep1
Name: dipeptidase 1
RGD ID: 620324
Description: Predicted to enable several functions, including beta-lactamase activity; metallodipeptidase activity; and zinc ion binding activity. Predicted to be involved in several processes, including carboxylic acid metabolic process; cellular response to nitric oxide; and glutathione catabolic process. Predicted to be located in apical part of cell; endoplasmic reticulum membrane; and extracellular space. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hepatoblastoma. Orthologous to human DPEP1 (dipeptidase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-lactamase; dipeptidase 1 (renal); microsomal dipeptidase; renal dipeptidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,118,270 - 68,143,781 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1968,118,453 - 68,143,775 (+)EnsemblGRCr8
mRatBN7.21951,209,831 - 51,237,004 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,219,660 - 51,235,257 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,014,788 - 58,029,351 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,694,560 - 58,709,533 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,913,384 - 60,927,951 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,973,447 - 55,998,830 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,982,740 - 55,998,208 (+)Ensemblrn6Rnor6.0
Rnor_5.01966,678,990 - 66,706,989 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,503,467 - 53,518,440 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,455,220 - 50,470,193 (+)NCBICelera
RGSC_v3.11953,508,370 - 53,523,966 (+)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP)
bisphenol F  (ISO)
bleomycin A2  (EXP)
Bufotalin  (ISO)
cadmium atom  (EXP)
carbon nanotube  (ISO)
carnosic acid  (ISO)
choline  (ISO)
cilastatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
erianin  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
indole-3-methanol  (EXP)
inulin  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
manganese(II) chloride  (EXP)
metformin  (ISO)
methimazole  (EXP)
mifepristone  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
nitrofen  (EXP)
ochratoxin A  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP)
paraquat  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
progesterone  (EXP)
propanal  (ISO)
S-nitrosoglutathione  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Primary structure of rat renal dipeptidase and expression of its mRNA in rat tissues and COS-1 cells. Adachi H, etal., Biochim Biophys Acta 1992 Oct 20;1132(3):311-4.
2. DPEP1 is a direct target of miR-193a-5p and promotes hepatoblastoma progression by PI3K/Akt/mTOR pathway. Cui X, etal., Cell Death Dis. 2019 Sep 20;10(10):701. doi: 10.1038/s41419-019-1943-0.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes. Hinojos CA, etal., Hypertension 2005 Apr;45(4):698-704. Epub 2005 Feb 14.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:6334084   PMID:8045301   PMID:8737157   PMID:8823187   PMID:9560193   PMID:11139399   PMID:11487543   PMID:11988094   PMID:12144777   PMID:12738806   PMID:15865404   PMID:17615681  
PMID:19056867   PMID:19879002   PMID:20031578   PMID:20435919   PMID:20824289   PMID:23376485   PMID:23533145   PMID:31442408  


Genomics

Comparative Map Data
Dpep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,118,270 - 68,143,781 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1968,118,453 - 68,143,775 (+)EnsemblGRCr8
mRatBN7.21951,209,831 - 51,237,004 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,219,660 - 51,235,257 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,014,788 - 58,029,351 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,694,560 - 58,709,533 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,913,384 - 60,927,951 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,973,447 - 55,998,830 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,982,740 - 55,998,208 (+)Ensemblrn6Rnor6.0
Rnor_5.01966,678,990 - 66,706,989 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,503,467 - 53,518,440 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,455,220 - 50,470,193 (+)NCBICelera
RGSC_v3.11953,508,370 - 53,523,966 (+)NCBI
Cytogenetic Map19q12NCBI
DPEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,613,308 - 89,641,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1689,613,308 - 89,638,456 (+)Ensemblhg38GRCh38
GRCh371689,679,716 - 89,707,948 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,214,501 - 88,232,338 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341688,214,500 - 88,232,338NCBI
Celera1674,743,127 - 74,769,330 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1675,374,386 - 75,400,655 (+)NCBIHuRef
CHM1_11691,091,422 - 91,116,106 (+)NCBICHM1_1
T2T-CHM13v2.01695,694,848 - 95,725,329 (+)NCBIT2T-CHM13v2.0
Dpep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,913,069 - 123,928,551 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,912,981 - 123,928,551 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388123,186,235 - 123,201,812 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,186,242 - 123,201,812 (+)Ensemblmm10GRCm38
MGSCv378125,710,135 - 125,725,712 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368126,072,332 - 126,087,314 (+)NCBIMGSCv36mm8
Celera8127,417,731 - 127,433,354 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map872.08NCBI
Dpep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555413,204,055 - 3,215,565 (+)Ensembl
ChiLan1.0NW_0049555413,204,421 - 3,215,514 (+)NCBIChiLan1.0ChiLan1.0
DPEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21899,399,032 - 99,426,756 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116105,315,996 - 105,342,405 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01670,365,900 - 70,392,377 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,971,984 - 89,997,978 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,975,105 - 89,997,978 (+)EnsemblpanPan2panpan1.1
DPEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,909,034 - 63,923,309 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,909,042 - 63,923,492 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha563,921,890 - 63,936,207 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0564,136,884 - 64,151,198 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,136,892 - 64,151,287 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,156,932 - 64,171,234 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0563,994,537 - 64,008,843 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,401,112 - 64,415,426 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dpep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,625,555 - 24,643,322 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641379,083 - 391,918 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936641379,112 - 384,711 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6361,197 - 376,616 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16361,187 - 385,757 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26488,005 - 503,439 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DPEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,963,509 - 74,987,469 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,977,290 - 74,987,546 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023669841183 - 2,804 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dpep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746310,248 - 315,654 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746310,361 - 321,053 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dpep1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11742,799,093 - 42,806,711 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:77
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000021397
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 60 81 81 80 49 53 49 6 289 145 10 59 72 92 31 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000021397   ⟹   ENSRNOP00000021397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,118,453 - 68,143,775 (+)Ensembl
mRatBN7.2 Ensembl1951,219,660 - 51,235,257 (+)Ensembl
Rnor_6.0 Ensembl1955,982,740 - 55,998,208 (+)Ensembl
RefSeq Acc Id: NM_053591   ⟹   NP_446043
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,128,158 - 68,143,131 (+)NCBI
mRatBN7.21951,219,637 - 51,234,612 (+)NCBI
Rnor_6.01955,983,210 - 55,998,183 (+)NCBI
Rnor_5.01966,678,990 - 66,706,989 (+)NCBI
RGSC_v3.41953,503,467 - 53,518,440 (+)RGD
Celera1950,455,220 - 50,470,193 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255783   ⟹   XP_006255845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,118,352 - 68,143,781 (+)NCBI
mRatBN7.21951,209,831 - 51,237,004 (+)NCBI
Rnor_6.01955,973,447 - 55,998,830 (+)NCBI
Rnor_5.01966,678,990 - 66,706,989 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063278335   ⟹   XP_063134405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,118,270 - 68,143,781 (+)NCBI
RefSeq Acc Id: NP_446043   ⟸   NM_053591
- Peptide Label: precursor
- UniProtKB: Q6IN35 (UniProtKB/Swiss-Prot),   P31430 (UniProtKB/Swiss-Prot),   A6IZW1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255845   ⟸   XM_006255783
- Peptide Label: isoform X1
- UniProtKB: Q6IN35 (UniProtKB/Swiss-Prot),   P31430 (UniProtKB/Swiss-Prot),   A6IZW1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021397   ⟸   ENSRNOT00000021397
RefSeq Acc Id: XP_063134405   ⟸   XM_063278335
- Peptide Label: isoform X1
- UniProtKB: Q6IN35 (UniProtKB/Swiss-Prot),   P31430 (UniProtKB/Swiss-Prot),   A6IZW1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P31430-F1-model_v2 AlphaFold P31430 1-410 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701217
Promoter ID:EPDNEW_R11741
Type:single initiation site
Name:Dpep1_2
Description:dipeptidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11742  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01955,982,719 - 55,982,779EPDNEW
RGD ID:13701218
Promoter ID:EPDNEW_R11742
Type:initiation region
Name:Dpep1_1
Description:dipeptidase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11741  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01955,983,198 - 55,983,258EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620324 AgrOrtholog
BioCyc Gene G2FUF-5340 BioCyc
Ensembl Genes ENSRNOG00000015880 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021397 ENTREZGENE
  ENSRNOT00000021397.4 UniProtKB/Swiss-Prot
Gene3D-CATH Metal-dependent hydrolases UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7100683 IMAGE-MGC_LOAD
InterPro Dipep_AS UniProtKB/Swiss-Prot
  Metal_Hydrolase UniProtKB/Swiss-Prot
  Pept_M19 UniProtKB/Swiss-Prot
KEGG Report rno:94199 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91569 IMAGE-MGC_LOAD
NCBI Gene 94199 ENTREZGENE
PANTHER PTHR10443 UniProtKB/Swiss-Prot
  PTHR10443:SF38 UniProtKB/Swiss-Prot
Pfam Peptidase_M19 UniProtKB/Swiss-Prot
PhenoGen Dpep1 PhenoGen
PROSITE RENAL_DIPEPTIDASE_1 UniProtKB/Swiss-Prot
  RENAL_DIPEPTIDASE_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015880 RatGTEx
Superfamily-SCOP SSF51556 UniProtKB/Swiss-Prot
UniProt A6IZW1 ENTREZGENE, UniProtKB/TrEMBL
  DPEP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6IN35 ENTREZGENE
UniProt Secondary Q6IN35 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-16 Dpep1  dipeptidase 1  Dpep1  dipeptidase 1 (renal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Dpep1  dipeptidase 1 (renal)    dipeptidase 1  Name updated 1299863 APPROVED
2002-08-07 Dpep1  dipeptidase 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expression is decreased 1.8 fold in SHR compared with WKY rats 1357414
gene_expression expressed in lung and kidney and small intestine 728405