Pou4f1 (POU class 4 homeobox 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Pou4f1 (POU class 4 homeobox 1) Rattus norvegicus
Analyze
Symbol: Pou4f1
Name: POU class 4 homeobox 1
RGD ID: 620074
Description: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of neuron apoptotic process and spermatogenesis. Predicted to be located in several cellular components, including chromatin; neuron projection; and nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human POU4F1 (POU class 4 homeobox 1); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; lead diacetate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brain-3A; brain-specific homeobox/POU domain protein 3A; brn-3A; Brn3a; POU domain, class 4, transcription factor 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81587,668,328 - 87,674,643 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1587,668,328 - 87,674,643 (-)EnsemblGRCr8
mRatBN7.21581,253,714 - 81,260,057 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1581,257,781 - 81,259,728 (-)EnsemblmRatBN7.2
Rnor_6.01588,618,255 - 88,622,712 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1588,620,470 - 88,622,413 (-)Ensemblrn6Rnor6.0
Rnor_5.01592,114,015 - 92,118,240 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41588,535,625 - 88,539,256 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1580,380,878 - 80,387,018 (-)NCBICelera
RGSC_v3.11588,553,052 - 88,553,272 (-)NCBI
Cytogenetic Map15q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell migration in hindbrain  (ISO)
cellular response to cytokine stimulus  (ISO,ISS)
cellular response to estradiol stimulus  (ISO,ISS)
central nervous system neuron differentiation  (ISO)
DNA-templated transcription  (IEA)
habenula development  (ISO)
heart development  (ISO)
innervation  (ISO)
intrinsic apoptotic signaling pathway by p53 class mediator  (ISO,ISS)
mesoderm development  (ISO)
negative regulation of apoptotic process  (ISO,TAS)
negative regulation of gene expression  (ISO)
negative regulation of neuron apoptotic process  (IMP,ISO)
negative regulation of programmed cell death  (ISO,ISS)
negative regulation of transcription by RNA polymerase II  (ISO)
nervous system development  (ISO)
neuron differentiation  (ISO)
neuron fate specification  (ISO)
neuron projection development  (ISO,ISS)
obsolete regulation of DNA-binding transcription factor activity  (ISO)
peripheral nervous system neuron development  (ISO)
peripheral nervous system neuron differentiation  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of gene expression  (ISO,ISS)
positive regulation of osteoclast differentiation  (ISO,ISS)
positive regulation of transcription by RNA polymerase II  (ISO)
proprioception involved in equilibrioception  (ISO)
regulation of cell cycle  (ISO,ISS)
regulation of DNA-templated transcription  (IEA,ISO)
regulation of neurogenesis  (ISO)
regulation of transcription by RNA polymerase II  (IBA,IEA)
sensory system development  (ISO)
spermatogenesis  (IEA,IEP)
suckling behavior  (ISO)
transcription by RNA polymerase II  (TAS)
trigeminal nerve development  (ISO)
ventricular compact myocardium morphogenesis  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transcriptional regulation by p53. Beckerman R and Prives C, Cold Spring Harb Perspect Biol. 2010 Aug;2(8):a000935. doi: 10.1101/cshperspect.a000935. Epub 2010 Apr 28.
2. The closely related POU family transcription factors Brn-3a and Brn-3b are expressed in distinct cell types in the testis. Budhram-Mahadeo V, etal., Int J Biochem Cell Biol. 2001 Oct;33(10):1027-39.
3. p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor. Budhram-Mahadeo V, etal., J Biol Chem. 1999 May 21;274(21):15237-44. doi: 10.1074/jbc.274.21.15237.
4. The BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosis. Ensor E, etal., J Biol Chem 2001 Feb 16;276(7):5204-12.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival. Wiggins AK, etal., J Cell Biol 2004 Oct 25;167(2):257-67. Epub 2004 Oct 18.
Additional References at PubMed
PMID:1383937   PMID:2739723   PMID:7623109   PMID:7935408   PMID:8290353   PMID:8621561   PMID:8876243   PMID:8955272   PMID:8972215   PMID:9448000   PMID:12810599   PMID:12934100  
PMID:15532030   PMID:15968082   PMID:16040009   PMID:16752387   PMID:17145718   PMID:17196582   PMID:17239249   PMID:17668438   PMID:18303621   PMID:18368538   PMID:18421303   PMID:18839516  
PMID:19877281   PMID:19906978   PMID:20096094   PMID:20228055   PMID:21315070   PMID:21734270   PMID:23805044   PMID:26200499   PMID:28594399  


Genomics

Comparative Map Data
Pou4f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81587,668,328 - 87,674,643 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1587,668,328 - 87,674,643 (-)EnsemblGRCr8
mRatBN7.21581,253,714 - 81,260,057 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1581,257,781 - 81,259,728 (-)EnsemblmRatBN7.2
Rnor_6.01588,618,255 - 88,622,712 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1588,620,470 - 88,622,413 (-)Ensemblrn6Rnor6.0
Rnor_5.01592,114,015 - 92,118,240 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41588,535,625 - 88,539,256 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1580,380,878 - 80,387,018 (-)NCBICelera
RGSC_v3.11588,553,052 - 88,553,272 (-)NCBI
Cytogenetic Map15q22NCBI
POU4F1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381378,598,362 - 78,603,552 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1378,598,362 - 78,603,552 (-)Ensemblhg38GRCh38
GRCh371379,172,497 - 79,177,687 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361378,071,228 - 78,075,696 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341378,071,232 - 78,075,696NCBI
Celera1360,071,661 - 60,076,129 (-)NCBICelera
Cytogenetic Map13q31.1NCBI
HuRef1359,873,428 - 59,878,003 (-)NCBIHuRef
CHM1_11379,141,107 - 79,145,483 (-)NCBICHM1_1
T2T-CHM13v2.01377,824,085 - 77,829,278 (-)NCBIT2T-CHM13v2.0
Pou4f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914104,699,111 - 104,705,554 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14104,699,112 - 104,705,435 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3814104,461,675 - 104,468,118 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14104,461,676 - 104,467,999 (-)Ensemblmm10GRCm38
MGSCv3714104,861,537 - 104,867,216 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3614103,347,999 - 103,353,678 (-)NCBIMGSCv36mm8
Celera14103,076,392 - 103,080,281 (-)NCBICelera
Cytogenetic Map14E2.3NCBI
cM Map1454.21NCBI
Pou4f1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540428,812,753 - 28,814,673 (+)Ensembl
ChiLan1.0NW_00495540428,812,762 - 28,818,024 (+)NCBIChiLan1.0ChiLan1.0
POU4F1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21479,962,702 - 80,181,037 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11378,718,089 - 78,769,633 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01359,821,614 - 59,829,671 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11378,863,468 - 78,863,992 (-)NCBIPanPan1.1PanPan1.1panPan2
POU4F1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12231,992,657 - 31,997,066 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2231,792,017 - 31,794,362 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02232,315,525 - 32,317,867 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2232,315,761 - 32,317,760 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12231,977,103 - 31,979,449 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02232,014,166 - 32,016,510 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02232,086,264 - 32,088,616 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pou4f1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945127,439,842 - 127,446,181 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365112,857,331 - 2,859,277 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365112,857,017 - 2,859,705 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POU4F1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1150,730,428 - 50,732,539 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11150,729,746 - 50,732,626 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21155,418,338 - 55,421,499 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POU4F1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1357,667,248 - 57,673,071 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604613,898,273 - 13,902,805 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pou4f1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475121,812,850 - 21,814,747 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475121,812,567 - 21,817,837 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pou4f1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11220,340,661 - 20,342,601 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pou4f1
39 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:50
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000012828
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1582194914108192169Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1574735564106469153Rat
1358354Srcrt5Stress Responsive Cort QTL 53.38blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1582503470108192169Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1582714037106778197Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
7411646Foco21Food consumption QTL 2123.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1584278281108192169Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1572716871101425383Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)1561710951106710951Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1575928947101425383Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1559257087104257087Rat
2313080Bss65Bone structure and strength QTL 653.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1567399137108192169Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1582194914108192169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)1560213984105213984Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)156244089297773284Rat
70182BpQTLcluster12Blood pressure QTL cluster 123.53arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)1572716871101425383Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1564571127108192169Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)1583700787108192169Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat

Markers in Region
PMC125354P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21581,257,804 - 81,258,078 (+)MAPPERmRatBN7.2
Rnor_6.01588,620,494 - 88,620,767NCBIRnor6.0
Rnor_5.01592,116,254 - 92,116,527UniSTSRnor5.0
RGSC_v3.41588,537,237 - 88,537,510UniSTSRGSC3.4
Celera1580,384,969 - 80,385,242UniSTS
Cytogenetic Map15q22UniSTS
Pou4f1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21581,257,337 - 81,257,415 (+)MAPPERmRatBN7.2
Rnor_6.01588,620,027 - 88,620,104NCBIRnor6.0
Rnor_5.01592,115,787 - 92,115,864UniSTSRnor5.0
RGSC_v3.41588,536,770 - 88,536,847UniSTSRGSC3.4
Celera1580,384,502 - 80,384,579UniSTS
Cytogenetic Map15q22UniSTS
UniSTS:465489  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21581,257,765 - 81,257,929 (+)MAPPERmRatBN7.2
Rnor_6.01588,620,455 - 88,620,618NCBIRnor6.0
Rnor_5.01592,116,215 - 92,116,378UniSTSRnor5.0
RGSC_v3.41588,537,198 - 88,537,361UniSTSRGSC3.4
Celera1580,384,930 - 80,385,093UniSTS
Cytogenetic Map15q22UniSTS
UniSTS:470675  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21581,257,776 - 81,257,929 (+)MAPPERmRatBN7.2
Rnor_6.01588,620,466 - 88,620,618NCBIRnor6.0
Rnor_5.01592,116,226 - 92,116,378UniSTSRnor5.0
RGSC_v3.41588,537,209 - 88,537,361UniSTSRGSC3.4
Celera1580,384,941 - 80,385,093UniSTS
Cytogenetic Map15q22UniSTS
UniSTS:276144  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21581,258,786 - 81,259,784 (+)MAPPERmRatBN7.2
Rnor_6.01588,621,472 - 88,622,469NCBIRnor6.0
Rnor_5.01592,117,134 - 92,118,131UniSTSRnor5.0
RGSC_v3.41588,538,315 - 88,539,312UniSTSRGSC3.4
Cytogenetic Map15q22UniSTS
Pou4f1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21581,258,900 - 81,259,735 (+)MAPPERmRatBN7.2
Rnor_6.01588,621,586 - 88,622,420NCBIRnor6.0
Rnor_5.01592,117,248 - 92,118,082UniSTSRnor5.0
RGSC_v3.41588,538,429 - 88,539,263UniSTSRGSC3.4
Celera1580,386,144 - 80,386,978UniSTS
Cytogenetic Map15q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 8 18 138 69 65 45 71 45 6 240 111 9 121 61 77 20 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000092174   ⟹   ENSRNOP00000074614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1581,257,781 - 81,259,728 (-)Ensembl
Rnor_6.0 Ensembl1588,620,470 - 88,622,413 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129142   ⟹   ENSRNOP00000104209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1587,672,395 - 87,674,643 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000157082   ⟹   ENSRNOP00000108265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1587,668,328 - 87,674,643 (-)Ensembl
RefSeq Acc Id: NM_001419538   ⟹   NP_001406467
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81587,668,328 - 87,674,643 (-)NCBI
mRatBN7.21581,253,714 - 81,260,029 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001406467 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK70502 (Get FASTA)   NCBI Sequence Viewer  
  EDM02474 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000108265
GenBank Protein P20266 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000074614   ⟸   ENSRNOT00000092174
RefSeq Acc Id: NP_001406467   ⟸   NM_001419538
- UniProtKB: A0A0G2K8H8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000104209   ⟸   ENSRNOT00000129142
Ensembl Acc Id: ENSRNOP00000108265   ⟸   ENSRNOT00000157082
Protein Domains
POU-specific

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620074 AgrOrtholog
BioCyc Gene G2FUF-12651 BioCyc
Ensembl Genes ENSRNOG00000060662 Ensembl
  ENSRNOG00000089245 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000157082 ENTREZGENE
Gene3D-CATH 1.10.260.40 UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Lambda_DNA-bd_dom_sf UniProtKB/Swiss-Prot
  POU UniProtKB/Swiss-Prot
  POU_dom UniProtKB/Swiss-Prot
  POU_domain_TF UniProtKB/Swiss-Prot
NCBI Gene 114503 ENTREZGENE
PANTHER POU DOMAIN UniProtKB/Swiss-Prot
  PTHR11636:SF42 UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
  Pou UniProtKB/Swiss-Prot
PhenoGen Pou4f1 PhenoGen
PRINTS POUDOMAIN UniProtKB/Swiss-Prot
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
  POU_1 UniProtKB/Swiss-Prot
  POU_2 UniProtKB/Swiss-Prot
  POU_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000060662 RatGTEx
  ENSRNOG00000089245 RatGTEx
SMART HOX UniProtKB/Swiss-Prot
  POU UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
  SSF47413 UniProtKB/Swiss-Prot
UniProt A0A0G2K8H8 ENTREZGENE
  A0ABK0LC39_RAT UniProtKB/TrEMBL
  A0ABK0LH94_RAT UniProtKB/TrEMBL
  A6HUB1_RAT UniProtKB/TrEMBL
  P20266 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q91XM4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-24 Pou4f1  POU class 4 homeobox 1  Pou4f1  POU domain, class 4, transcription factor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Pou4f1  POU domain, class 4, transcription factor 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Pou4f1  POU domain, class 4, transcription factor 1      Symbol and Name status set to provisional 70820 PROVISIONAL