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Gene: Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6) Rattus norvegicus

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Symbol:

Entpd6

Name:

ectonucleoside triphosphate diphosphohydrolase 6

RGD ID:

619725

Description:

Enables pyrophosphatase activity. Involved in response to calcium ion and response to magnesium ion. Located in cell surface and extracellular space. Orthologous to human ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6); PARTICIPATES IN purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CD39 antigen-like 2; NTPDase 6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	entpd6 (ectonucleoside triphosphate diphosphohydrolase 6 (putative))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GDA1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GDA1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	NTPase	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	uda-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	entpd6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	entpd6	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Allele / Splice:

Entpd6^{Tn(sb-T2/Bart3)2.174Mcwi}

Genetic Models:

F344-Entpd6^{Tn(sb-T2/Bart3)2.174Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	160,036,055 - 160,058,580 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	160,036,121 - 160,059,451 (+)	Ensembl				GRCr8
mRatBN7.2	3	139,575,659 - 139,598,163 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	139,575,686 - 139,598,154 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	143,471,519 - 143,494,099 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	152,055,255 - 152,077,835 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	149,804,015 - 149,826,553 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	146,546,424 - 146,568,828 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	146,546,387 - 146,568,825 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	152,905,464 - 152,927,857 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	141,385,480 - 141,407,860 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	138,337,640 - 138,359,993 (+)	NCBI		Celera
RGSC_v3.1	3	141,291,052 - 141,313,433 (+)	NCBI
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

obesity (ISO)

seminoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cisplatin (ISO)

clobetasol (ISO)

dexamethasone (ISO)

doxorubicin (ISO)

ethanol (ISO)

fipronil (EXP)

furan (EXP)

indometacin (ISO)

nickel sulfate (ISO)

paracetamol (EXP,ISO)

rotenone (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triptonide (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

response to calcium ion (IDA)

response to magnesium ion (IDA)

Cellular Component

cell surface (IDA)

extracellular region (IEA,ISO)

extracellular space (IDA)

Golgi apparatus (IBA,IEA,ISO)

Golgi membrane (IEA)

plasma membrane (IEA,ISO)

Molecular Function

CDP phosphatase activity (IDA,IEA,ISO)

GDP phosphatase activity (IDA,IEA,ISO)

guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity (IDA)

hydrolase activity (IEA)

IDP phosphatase activity (IDA,IEA,ISO)

nucleoside diphosphate phosphatase activity (IDA,IEA,ISO)

ribonucleoside triphosphate phosphatase activity (IDA)

UDP phosphatase activity (IDA,IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

purine metabolic pathway (IEA)

pyrimidine metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Sequencing, functional expression and characterization of rat NTPDase6, a nucleoside diphosphatase and novel member of the ecto-nucleoside triphosphate diphosphohydrolase family.	Braun N, etal., Biochem J 2000 Nov 1;351 Pt 3:639-47.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10948193	PMID:14529283	PMID:23302703	PMID:23376485

Genomics

Comparative Map Data

Entpd6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	160,036,055 - 160,058,580 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	160,036,121 - 160,059,451 (+)	Ensembl				GRCr8
mRatBN7.2	3	139,575,659 - 139,598,163 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	139,575,686 - 139,598,154 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	143,471,519 - 143,494,099 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	152,055,255 - 152,077,835 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	149,804,015 - 149,826,553 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	146,546,424 - 146,568,828 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	146,546,387 - 146,568,825 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	152,905,464 - 152,927,857 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	141,385,480 - 141,407,860 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	138,337,640 - 138,359,993 (+)	NCBI		Celera
RGSC_v3.1	3	141,291,052 - 141,313,433 (+)	NCBI
Cytogenetic Map	3	q41	NCBI

ENTPD6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	25,195,712 - 25,228,075 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	25,195,693 - 25,228,075 (+)	Ensembl			hg38	GRCh38
GRCh37	20	25,176,348 - 25,208,711 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	25,124,372 - 25,155,360 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	25,124,371 - 25,155,360	NCBI
Celera	20	25,250,075 - 25,281,095 (+)	NCBI		Celera
Cytogenetic Map	20	p11.21	NCBI
HuRef	20	25,133,642 - 25,164,663 (+)	NCBI		HuRef
CHM1_1	20	25,177,223 - 25,208,244 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	25,260,296 - 25,293,060 (+)	NCBI		T2T-CHM13v2.0

Entpd6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	150,590,959 - 150,613,595 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	150,590,962 - 150,613,595 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	150,748,980 - 150,771,675 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	150,749,042 - 150,771,675 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	150,574,817 - 150,597,410 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	150,440,590 - 150,463,114 (+)	NCBI		MGSCv36	mm8
Celera	2	151,982,124 - 152,004,717 (+)	NCBI		Celera
Cytogenetic Map	2	G3	NCBI
cM Map	2	74.74	NCBI

Entpd6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	31,233,553 - 31,244,369 (+)	Ensembl
ChiLan1.0	NW_004955415	31,219,909 - 31,245,107 (+)	NCBI	ChiLan1.0	ChiLan1.0

ENTPD6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	26,069,393 - 26,105,731 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	26,066,122 - 26,101,884 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	25,138,856 - 25,169,765 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	25,544,808 - 25,576,712 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	25,544,880 - 25,576,707 (+)	Ensembl			panPan2	panpan1.1

ENTPD6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	1,374,793 - 1,422,625 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	1,374,199 - 1,420,802 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	1,404,549 - 1,450,380 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	1,615,237 - 1,661,162 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	1,615,277 - 1,661,177 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	1,456,204 - 1,501,946 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	1,580,817 - 1,626,596 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	1,548,077 - 1,593,906 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Entpd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	147,178,218 - 147,207,324 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936620	598,592 - 627,822 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936620	598,677 - 627,766 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ENTPD6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	30,908,252 - 30,934,083 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	30,908,747 - 30,930,774 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ENTPD6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666078	7,827,280 - 7,857,456 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Entpd6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624939	313,768 - 333,694 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624939	313,763 - 333,640 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Entpd6
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	130,457,415 - 130,480,444 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Entpd6
449 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	476
Count of miRNA genes:	230
Interacting mature miRNAs:	285
Transcripts:	ENSRNOT00000009946
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
1582233	Insul10	Insulin level QTL 10	5.4	0.0015	blood insulin amount (VT:0001560)	serum insulin level times blood glucose level (CMO:0002040)	3	133259579	178259579	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	133134628	178134628	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	141508991	166376254	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	117537367	162537367	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	125116475	170116475	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	122395989	167395989	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	141508991	177728348	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	131036586	176036586	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	137114333	182114333	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	131036586	176036586	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	116188400	161188400	Rat

Markers in Region

RH131966

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	139,597,957 - 139,598,143 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	146,568,623 - 146,568,808	NCBI	Rnor6.0
Rnor_5.0	3	152,927,654 - 152,927,839	UniSTS	Rnor5.0
RGSC_v3.4	3	141,407,657 - 141,407,842	UniSTS	RGSC3.4
Celera	3	138,359,790 - 138,359,975	UniSTS
RH 3.4 Map	3	1197.22	UniSTS
Cytogenetic Map	3	q41	UniSTS

UniSTS:234554

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	139,597,847 - 139,598,051 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	146,568,513 - 146,568,716	NCBI	Rnor6.0
Rnor_5.0	3	152,927,544 - 152,927,747	UniSTS	Rnor5.0
RGSC_v3.4	3	141,407,547 - 141,407,750	UniSTS	RGSC3.4
Celera	3	138,359,680 - 138,359,883	UniSTS
Cytogenetic Map	3	q41	UniSTS

Genetic Models

This gene Entpd6 is modified in the following models/strains:

F344-Entpd6^{Tn(sb-T2/Bart3)2.174Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001429515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_053498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ277748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000009946 ⟹ ENSRNOP00000009946

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	160,036,121 - 160,059,451 (+)	Ensembl
mRatBN7.2 Ensembl	3	139,575,686 - 139,598,154 (+)	Ensembl
Rnor_6.0 Ensembl	3	146,546,387 - 146,568,825 (+)	Ensembl

RefSeq Acc Id:

NM_053498 ⟹ NP_445950

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	160,036,119 - 160,058,580 (+)	NCBI
mRatBN7.2	3	139,575,700 - 139,598,161 (+)	NCBI
Rnor_6.0	3	146,546,446 - 146,568,826 (+)	NCBI
Rnor_5.0	3	152,905,464 - 152,927,857 (+)	NCBI
RGSC_v3.4	3	141,385,480 - 141,407,860 (+)	RGD
Celera	3	138,337,640 - 138,359,993 (+)	RGD

Sequence:

show sequence

ATCGGCTAAGGTCTGGTTCCACGCGTTGAGGCTCTGTTGACGCGGACTGGCGCTGGAGAGCCAA
GCGCTCGGTGTGTGGTCGCTGTCTGCCTCCAGCACCGGCTACATAGTCCCTAGCAGACTGAGAA
ATGAGAAAAATACCAAACCATGGGACCTTGCGGATGACGAAGGTGGCGTATCCCCTGGGACTGT
GCGTGGGCCTGTTCATCTATGTTGCCTATATCAAGTGGCACCGGGCCTCCGCCGCCCAGGCCTT
CTTCACCATTGCTGGGGCTGCCTCAGGAGTGCGGTGGACCCAACAGGCCTTCAGCTCTCCAGAC
TCAGCCACACGTGGTCACGAGGTCTTCTATGGGATCATGTTTGATGCCGGGAGTACCGGCACCC
GCATCCACGTCTTCCAGTTTGCCCGGCCACCTGGAGAAACTCCCACCTTGACCCACGAAACCTT
CAAAGCTCTGAAGCCTGGGCTTTCTGCGTATGCCGATGATGTTGAAAAGAGCGCCCAAGGGATC
CAGGAGCTTCTGAATGTCGCCAAGCAACACATTCCATACGACTTCTGGAAGGCCACCCCTCTGG
TTCTCAAGGCCACAGCTGGTCTGCGCCTGCTGCCGGGAGAAAAGGCTCAGAAGTTGCTGCAAAA
GGTGAAGGAGGTGTTTAAGGCATCACCCTTCCTTGTAGGGGATGACTGTGTTTCCATCATGAAT
GGCACAGATGAAGGTGTTTCGGCTTGGATCACTGTCAACTTCCTGACAGGCAGTCTGAAGACCC
CAGGAAGCAGCAGTGTGGGCATGCTGGACTTGGGCGGAGGATCCACTCAGATCACCTTCCTCCC
ACGTGTCGAGGGTACCCTGCAGGCCTCCCCACCCGGCCACCTGACAGCGCTGCAGATGTTTAAC
AGGACTTTCAAGCTGTATTCCTACAGCTACCTGGGGCTGGGACTGATGTCGGCACGACTGGCTA
TCTTGGGTGGTGTGGAGGGGAAACCTGCTGAGGATGACAAGGAACTGGTCAGCCCCTGTCTGTC
TCCCCGGTTCAGAGGAAAGTGGGAGCATGCGGAGGTCACCTATAGAATTTCAGGACAGAAGGCA
GTGGGCCTCTACGAGCTGTGTGCCAGCAGGGTATCAGAAGTCCTCCGCAATAAAGTACACAGGA
CAGAAGAGGCGCAGCACGTGGACTTCTATGCGTTTTCCTACTACTACGACCTTGCTGCCAGCTT
TGGCCTTATAGATGCAGAGAAAGGAGGCAGCCTTGTAGTTGGAGACTTTGAGATAGCAGCCAAG
TATGTCTGCCGCACTCTGGAGACACAGCCTCCAAGCAGCCCCTTTGCTTGCATGGACCTCACCT
ACATCAGCCTCCTGCTCCACGAGTTTGGTTTTCCCGGGGACAAGGTACTGAAGCTGGCTCGGAA
AATTGACAATGTTGAAACCAGCTGGGCTCTGGGGGCTATTTTTCATTACATCGACTCCCTGAAG
AGACAGAAGGTTCCTGCCTTGTAGCAGCCTCGAACTAGTCCCCACCCTAGCCAGATTTCCGAGG
CTCCCAACTCCACGGACCCCTCTATCTTGGAAGTGACACCATCCTTGAGGAGCCTGCATCTGGT
TGAGACCCGCCTCTGTGCCTGCAGTGTCATCTCCTGCAGATTTGCCTGGGACATGACCCATGTA
CTGGCTCTGCTACACCACACTAGCTGGGGCAGGGCCAGGGTAGGAATGCTGCCTGGCCTGAGGC
CATCTCCCTGTCTTACCCCCAAATGGGCGGGGAGCCAGCTGGGGCCCAGGGCACATGCTAAGGT
AGAGACGCAGCCCTGCTCTTATCCCGTCCGTGTGCAGGATTGTGGCTGCTTTTGTGTGTTTCTG
TGACTTGAGTCTTGTTTTGTCTCCCAGCCCCCGTTCCCTCATGAGTTGGGCCTCTCTGCCTTCC
CAGAGTTTGGCGAGATGAAGTAACTGGCCCAAACGCAGTGCAAGGGGAGCACATTTTGAGTGTG
GCCATCTCTTCCTCGGGATAGACGTGAAGTTACCTGGAGGTTTGCTGTCCCACCTTTGGATGGT
ATAGCATTCATTGATGTGGGGACATTGAGTAGGAAGGAGATGGGGCAGTGCCTCTTTATAGACC
TTTGCAGAGCATGTGGGTGTGAGCAGAGCTATGAGAATGTTCAGGGCTGCGTGCTCAAGTACTA
CCTTGCAAGCTGTGAGCGCTGTACGTTAAAACTGAGCCCCTCTTCTGGACACAGCGGTGTCCCC
GTGAATGTATTACTGCTATGAGCCACTTGCAGACCAGTGGGGCAGGTTAGAAAGCTCAGCCCTA
GAACCAGACTACCCCTCACCCCACCCTCCTTACTCGGCTGCAGCTGGCTTCCCCGTGGTCCCCT
CAGTGAATGTACAGTTCATAGAGTAAGCTGAGCCACCACCGTTCAACTCCAAATAAAGGTTTAC
AAGGGTTTCAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006235218 ⟹ XP_006235280

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	160,036,118 - 160,058,578 (+)	NCBI
mRatBN7.2	3	139,575,700 - 139,598,163 (+)	NCBI
Rnor_6.0	3	146,546,424 - 146,568,828 (+)	NCBI
Rnor_5.0	3	152,905,464 - 152,927,857 (+)	NCBI

Sequence:

show sequence

TAGGCGGAGACAGCTCCTCCCGATCGGCTAAGGTCTGGTTCCACGCGTTGAGGCTCTGTTGACG
CGGACTGGCGCTGGAGAGCCAAGCGCTCGGTGTGTGGTCGCTGTCTGCCTCCAGGTACGCCACT
ACATGTCCTGAGGGGCCGAGGGCGCCGTGCAGGCACCGGCTACATAGTCCCTAGCAGACTGAGA
AATGAGAAAAATACCAAACCATGGGACCTTGCGGATGACGAAGGTGGCGTATCCCCTGGGACTG
TGCGTGGGCCTGTTCATCTATGTTGCCTATATCAAGTGGCACCGGGCCTCCGCCGCCCAGGCCT
TCTTCACCATTGCTGGGGCTGCCTCAGGAGTGCGGTGGACCCAACAGGCCTTCAGCTCTCCAGA
CTCAGCCACACGTGGTCACGAGGTCTTCTATGGGATCATGTTTGATGCCGGGAGTACCGGCACC
CGCATCCACGTCTTCCAGTTTGCCCGGCCACCTGGAGAAACTCCCACCTTGACCCACGAAACCT
TCAAAGCTCTGAAGCCTGGGCTTTCTGCGTATGCCGATGATGTTGAAAAGAGCGCCCAAGGGAT
CCAGGAGCTTCTGAATGTCGCCAAGCAACACATTCCATACGACTTCTGGAAGGCCACCCCTCTG
GTTCTCAAGGCCACAGCTGGTCTGCGCCTGCTGCCGGGAGAAAAGGCTCAGAAGTTGCTGCAAA
AGGTGAAGGAGGTGTTTAAGGCATCACCCTTCCTTGTAGGGGATGACTGTGTTTCCATCATGAA
TGGCACAGATGAAGGTGTTTCGGCTTGGATCACTGTCAACTTCCTGACAGGCAGTCTGAAGACC
CCAGGAAGCAGCAGTGTGGGCATGCTGGACTTGGGCGGAGGATCCACTCAGATCACCTTCCTCC
CACGTGTCGAGGGTACCCTGCAGGCCTCCCCACCCGGCCACCTGACAGCGCTGCAGATGTTTAA
CAGGACTTTCAAGCTGTATTCCTACAGCTACCTGGGGCTGGGACTGATGTCGGCACGACTGGCT
ATCTTGGGTGGTGTGGAGGGGAAACCTGCTGAGGATGACAAGGAACTGGTCAGCCCCTGTCTGT
CTCCCCGGTTCAGAGGAAAGTGGGAGCATGCGGAGGTCACCTATAGAATTTCAGGACAGAAGGC
AGTGGGCCTCTACGAGCTGTGTGCCAGCAGGGTATCAGAAGTCCTCCGCAATAAAGTACACAGG
ACAGAAGAGGCGCAGCACGTGGACTTCTATGCGTTTTCCTACTACTACGACCTTGCTGCCAGCT
TTGGCCTTATAGATGCAGAGAAAGGAGGCAGCCTTGTAGTTGGAGACTTTGAGATAGCAGCCAA
GTATGTCTGCCGCACTCTGGAGACACAGCCTCCAAGCAGCCCCTTTGCTTGCATGGACCTCACC
TACATCAGCCTCCTGCTCCACGAGTTTGGTTTTCCCGGGGACAAGGTACTGAAGCTGGCTCGGA
AAATTGACAATGTTGAAACCAGCTGGGCTCTGGGGGCTATTTTTCATTACATCGACTCCCTGAA
GAGACAGAAGGTTCCTGCCTTGTAGCAGCCTCGAACTAGTCCCCACCCTAGCCAGATTTCCGAG
GCTCCCAACTCCACGGACCCCTCTATCTTGGAAGTGACACCATCCTTGAGGAGCCTGCATCTGG
TTGAGACCCGCCTCTGTGCCTGCAGTGTCATCTCCTGCAGATTTGCCTGGGACATGACCCATGT
ACTGGCTCTGCTACACCACACTAGCTGGGGCAGGGCCAGGGTAGGAATGCTGCCTGGCCTGAGG
CCATCTCCCTGTCTTACCCCCAAATGGGCGGGGAGCCAGCTGGGGCCCAGGGCACATGCTAAGG
TAGAGACGCAGCCCTGCTCTTATCCCGTCCGTGTGCAGGATTGTGGCTGCTTTTGTGTGTTTCT
GTGACTTGAGTCTTGTTTTGTCTCCCAGCCCCCGTTCCCTCATGAGTTGGGCCTCTCTGCCTTC
CCAGAGTTTGGCGAGATGAAGTAACTGGCCCAAACGCAGTGCAAGGGGAGCACATTTTGAGTGT
GGCCATCTCTTCCTCGGGATAGACGTGAAGTTACCTGGAGGTTTGCTGTCCCACCTTTGGATGG
TATAGCATTCATTGATGTGGGGACATTGAGTAGGAAGGAGATGGGGCAGTGCCTCTTTATAGAC
CTTTGCAGAGCATGTGGGTGTGAGCAGAGCTATGAGAATGTTCAGGGCTGCGTGCTCAAGTACT
ACCTTGCAAGCTGTGAGCGCTGTACGTTAAAACTGAGCCCCTCTTCTGGACACAGCGGTGTCCC
CGTGAATGTATTACTGCTATGAGCCACTTGCAGACCAGTGGGGCAGGTTAGAAAGCTCAGCCCT
AGAACCAGACTACCCCTCACCCCACCCTCCTTACTCGGCTGCAGCTGGCTTCCCCGTGGTCCCC
TCAGTGAATGTACAGTTCATAGAGTAAGCTGAGCCACCACCGTTCAACTCCAAATAAAGGTTTA
CAAGGGTTTCTC

hide sequence

RefSeq Acc Id:

XM_063284740 ⟹ XP_063140810

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	160,036,085 - 160,058,578 (+)	NCBI

RefSeq Acc Id:

XR_010064708

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	160,036,055 - 160,052,414 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001416444	(Get FASTA)	NCBI Sequence Viewer
	NP_445950	(Get FASTA)	NCBI Sequence Viewer
	XP_006235280	(Get FASTA)	NCBI Sequence Viewer
	XP_063140810	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAC16598	(Get FASTA)	NCBI Sequence Viewer
	EDL86140	(Get FASTA)	NCBI Sequence Viewer
	EDL86141	(Get FASTA)	NCBI Sequence Viewer
	EDL86142	(Get FASTA)	NCBI Sequence Viewer
	EDL86143	(Get FASTA)	NCBI Sequence Viewer
	EDL86144	(Get FASTA)	NCBI Sequence Viewer
	EDL86145	(Get FASTA)	NCBI Sequence Viewer
	EDL86146	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000009946
	ENSRNOP00000009946.3
GenBank Protein	Q9ER31	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_445950 ⟸ NM_053498

- UniProtKB:

Q9ER31 (UniProtKB/Swiss-Prot), A6KHG0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRKIPNHGTLRMTKVAYPLGLCVGLFIYVAYIKWHRASAAQAFFTIAGAASGVRWTQQAFSSPD
SATRGHEVFYGIMFDAGSTGTRIHVFQFARPPGETPTLTHETFKALKPGLSAYADDVEKSAQGI
QELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMN
GTDEGVSAWITVNFLTGSLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFN
RTFKLYSYSYLGLGLMSARLAILGGVEGKPAEDDKELVSPCLSPRFRGKWEHAEVTYRISGQKA
VGLYELCASRVSEVLRNKVHRTEEAQHVDFYAFSYYYDLAASFGLIDAEKGGSLVVGDFEIAAK
YVCRTLETQPPSSPFACMDLTYISLLLHEFGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLK
RQKVPAL

hide sequence

RefSeq Acc Id:

XP_006235280 ⟸ XM_006235218

- Peptide Label:

isoform X1

- Sequence:

show sequence

MRKIPNHGTLRMTKVAYPLGLCVGLFIYVAYIKWHRASAAQAFFTIAGAASGVRWTQQAFSSPD
SATRGHEVFYGIMFDAGSTGTRIHVFQFARPPGETPTLTHETFKALKPGLSAYADDVEKSAQGI
QELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMN
GTDEGVSAWITVNFLTGSLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFN
RTFKLYSYSYLGLGLMSARLAILGGVEGKPAEDDKELVSPCLSPRFRGKWEHAEVTYRISGQKA
VGLYELCASRVSEVLRNKVHRTEEAQHVDFYAFSYYYDLAASFGLIDAEKGGSLVVGDFEIAAK
YVCRTLETQPPSSPFACMDLTYISLLLHEFGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLK
RQKVPAL

hide sequence

Ensembl Acc Id:

ENSRNOP00000009946 ⟸ ENSRNOT00000009946

RefSeq Acc Id:	XP_063140810 ⟸ XM_063284740
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9ER31-F1-model_v2	AlphaFold	Q9ER31	1-455	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692517

Promoter ID:

EPDNEW_R3042

Type:

initiation region

Name:

Entpd6_1

Description:

ectonucleoside triphosphate diphosphohydrolase 6

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	146,546,432 - 146,546,492	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:619725	AgrOrtholog
BioCyc Gene	G2FUF-47338	BioCyc
Ensembl Genes	ENSRNOG00000007427	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000009946	ENTREZGENE
	ENSRNOT00000009946.6	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.420.40	UniProtKB/Swiss-Prot
	Exopolyphosphatase. Domain 2	UniProtKB/Swiss-Prot
InterPro	GDA1_CD39_NTPase	UniProtKB/Swiss-Prot
KEGG Report	rno:85260	UniProtKB/Swiss-Prot
NCBI Gene	85260	ENTREZGENE
PANTHER	ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 6	UniProtKB/Swiss-Prot
	PTHR11782	UniProtKB/Swiss-Prot
Pfam	GDA1_CD39	UniProtKB/Swiss-Prot
PhenoGen	Entpd6	PhenoGen
PROSITE	GDA1_CD39_NTPASE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000007427	RatGTEx
UniProt	A6KHG0	ENTREZGENE, UniProtKB/TrEMBL
	A6KHG2_RAT	UniProtKB/TrEMBL
	A6KHG3_RAT	UniProtKB/TrEMBL
	A6KHG4_RAT	UniProtKB/TrEMBL
	A6KHG5_RAT	UniProtKB/TrEMBL
	ENTP6_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-01-20	Entpd6	ectonucleoside triphosphate diphosphohydrolase 6			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Entpd6	ectonucleoside triphosphate diphosphohydrolase 6			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_function	preferentially hydrolyses nucleoside 5'-diphosphates	727304
gene_protein	455 amino acids; 50 (49.97) kDa	727304

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)