Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6)

Gene: Entpd6 (ectonucleoside triphosphate diphosphohydrolase 6) Chinchilla lanigera

Analyze

Symbol:

Entpd6

Name:

ectonucleoside triphosphate diphosphohydrolase 6

RGD ID:

8945699

Description:

ENCODES a protein that exhibits CDP phosphatase activity (ortholog); GDP phosphatase activity (ortholog); guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity (ortholog); INVOLVED IN response to calcium ion (ortholog); response to magnesium ion (ortholog); ASSOCIATED WITH genetic disease (ortholog); obesity (ortholog); seminoma (ortholog); FOUND IN cell surface (ortholog); extracellular region (ortholog); extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955415	31,219,909 - 31,245,107 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

obesity (ISO)

seminoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

response to calcium ion (ISO)

response to magnesium ion (ISO)

Cellular Component

cell surface (ISO)

extracellular region (ISO)

extracellular space (ISO)

Golgi apparatus (ISO)

plasma membrane (ISO)

Molecular Function

CDP phosphatase activity (ISO)

GDP phosphatase activity (ISO)

guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity (ISO)

IDP phosphatase activity (ISO)

nucleoside diphosphate phosphatase activity (ISO)

ribonucleoside triphosphate phosphatase activity (ISO)

UDP phosphatase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Entpd6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955415	31,219,909 - 31,245,107 (+)	NCBI	ChiLan1.0	ChiLan1.0

ENTPD6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	25,195,712 - 25,228,075 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	25,195,693 - 25,228,075 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	25,176,348 - 25,208,711 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	25,124,372 - 25,155,360 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	25,124,371 - 25,155,360	NCBI
Celera	20	25,250,075 - 25,281,095 (+)	NCBI		Celera
Cytogenetic Map	20	p11.21	NCBI
HuRef	20	25,133,642 - 25,164,663 (+)	NCBI		HuRef
CHM1_1	20	25,177,223 - 25,208,244 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	25,260,296 - 25,293,060 (+)	NCBI		T2T-CHM13v2.0

Entpd6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	150,590,959 - 150,613,595 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	150,590,962 - 150,613,595 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	150,748,980 - 150,771,675 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	150,749,042 - 150,771,675 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	150,574,817 - 150,597,410 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	150,440,590 - 150,463,114 (+)	NCBI		MGSCv36	mm8
Celera	2	151,982,124 - 152,004,717 (+)	NCBI		Celera
Cytogenetic Map	2	G3	NCBI
cM Map	2	74.74	NCBI

Entpd6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	160,036,055 - 160,058,580 (+)	NCBI		GRCr8
mRatBN7.2	3	139,575,659 - 139,598,163 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	139,575,686 - 139,598,154 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	143,471,519 - 143,494,099 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	152,055,255 - 152,077,835 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	149,804,015 - 149,826,553 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	146,546,424 - 146,568,828 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	146,546,387 - 146,568,825 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	152,905,464 - 152,927,857 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	141,385,480 - 141,407,860 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	141,291,052 - 141,313,433 (+)	NCBI
Celera	3	138,337,640 - 138,359,993 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

ENTPD6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	26,069,393 - 26,105,731 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	26,066,122 - 26,101,884 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	25,138,856 - 25,169,765 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	25,544,808 - 25,576,712 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	25,544,880 - 25,576,707 (+)	Ensembl	panpan1.1		panPan2

ENTPD6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	1,374,793 - 1,422,625 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	1,374,199 - 1,420,802 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	1,404,549 - 1,450,380 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	1,615,237 - 1,661,162 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	1,615,277 - 1,661,177 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	1,456,204 - 1,501,946 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	1,580,817 - 1,626,596 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	1,548,077 - 1,593,906 (+)	NCBI		UU_Cfam_GSD_1.0

Entpd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	147,178,218 - 147,207,324 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936620	598,592 - 627,822 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936620	598,677 - 627,766 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ENTPD6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	30,908,252 - 30,934,083 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	30,908,747 - 30,930,774 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ENTPD6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666078	7,827,280 - 7,857,456 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Entpd6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624939	313,768 - 333,694 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624939	313,763 - 333,640 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005380988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01016671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01016672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01241622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005380988 ⟹ XP_005381045

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955415	31,219,909 - 31,245,107 (+)	NCBI

Sequence:

show sequence

ATGGAAAGCAGCCTGCCTGGGTTTTACACTCCAGGGACACAGACTCCCTGGGCAGCAGCACTGA
AGGATATCCTCTTTCCAGATGGGGAACGCTGGAAACAGAACCTGGGATGCCCTGCCCAGCGGTT
CCTCCAGATGTTGCTCCAGAACGACAAAAAAGTACTTTCTTTTCCTTTAGAGACTCCCACCTTG
ACCCACGAGACCTTTAAAGCGCTGAAGCCAGGGCTTTCTGCTTATGCTGATGATGTGGAGAAGA
GTGCTCAAGGGATCCAGGAGCTGCTGGATGTTGCTAAGCAGGACATTCCGTTTGACTTATGGAA
GGCCACCCCGCTGGTCCTCAAGGCCACAGCCGGCTTGCGCCTGTTACCTGGAGAGAAGGCTCAG
AAGCTGCTGCAGAAGGTGAAGGAGGTGTTTAAGGCATCACCTTTCCTGGTAGGGGACGACTGTG
TTTCCATCATGAACGGAACTGACGAAGGTGTCTCTGCGTGGATCACCGTCAACTTCCTGACAGG
CAGCTTGCGAGGCCCGGGCAGGAGCAGCGTGGGCATGCTGGATCTGGGCGGCGGGTCCACTCAG
ATCACCTTCCTTCCGCGGGCCGAGGGCACCCTGGAGGCCTCCCCACCTGGCCACCTGACGTCCC
TGCAGATGTTTAACAGGACCTATAGGCTGTATTCTCACAGCTACCTGGGGCTGGGACTGATGTC
GGCACGGCTGGCGATCCTGGGTGGAGTGGAAGGGAGACCTGCCAAGGACGGGAAGGAGTTGGTT
AGCGCTTGTCTGTCTCCCGGGTTCAGAGGCGAGTGGGAGCATGCGGAAATAACGTACAGGATCT
CAGGACAGAAGGCAGGGCGTCTCCATGAGCCTTGTGCCAGCAGGGTGTCTGAAGTCCTCCGAAA
CAAGGTGCACAGGGCAGAAGAGGCAGGACACGTGGACTTCTATGCCTTCTCCTACTACTATGAC
CTGGCGGCCAGTGTGGGTCTCATCGATGCGGAGAAGGGAGGCAGCGTCACAGTCGAGGACTTCG
AGATCGCAGCTAAGTACATGTGCCGGACCCTGGGTGCCCAACCGCACCGCAGCCCTTTCCTCTG
CATGGACCTCACCTATGTCAGCCTGCTGCTCCGCGAGCTCGGCTTCCGCGGGGACAAAGTGCTG
AAGCTGACTCGGAAAATTGACAATGTGGAGACCAGCTGGGCTCTAGGGGCCATTTTCCACTACA
TCGACTCCCTGAACAGACGGAAGAGTACAGCCTGGTAGCAGCTGGGTCCCGGCCAGCCCCAAGC
AGCGTTCCAGGCCATCCGACAGACCCTTCGTCTGGACCTGACCCCATCCGGCAGGAGCCCTGCT
GCCGAAGTCCCTCTGCACATCTGCCACAGCACAGAAGGTGGGCTGCTGGGCACCCGCCTCAGAG
GGCAGGCCTGGGCCGTGGCTCCGGGTGGACATGAGCCATGTGTGGCCAAGGGCACTTGCCGTTC
CCATCCCCAGCTGTGGGGCTGTGGCTGCCGCGTGTGTCCCTGTGTGTGAATCTTTCACCCCTGA
GTCTTGTTGACTTACCTGAGGGCTTCCCGATTCCCTGGGGGAGCAGAGCAGGACCCTGGGCCTT
CTGACCGCATCTCCAGTGAGGTTCTCCCCATGCTGGAAAGGTGAAGCCACCCAGAGATGTGGGG
CTGATCGGTGGGGGACACTGAGTAGGCGACCCTTCTCTGTGAAGCTATACCAGCTGCAGAGTCC
CCAGAAAATGGGTGAGGGCGGACTTACATAGGAGCAGTGCCAGCCATGCTGCCTGAGTCCCAGG
TGCTGTGTGAGCCACATCCATGGCCCTTTCTGACACCCGCACCATGTCTCCATGAATGTACTGC
GCGGGAGCCATGTGGGATGGTGTGCGCCCCATGCTGGCCCTGGCCGCAGCCTTCCAGATCCAAC
GAGGCTCCCTCAGTGAATGTACAGCTCTGCTCTGCGCTCTGCCGTGAATAAAGGTTCAGAGCTC
CTCCCAGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005381045	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000022805
	ENSCLAP00000022805.1

RefSeq Acc Id:

XP_005381045 ⟸ XM_005380988

- UniProtKB:

A0A8C2VZP5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MESSLPGFYTPGTQTPWAAALKDILFPDGERWKQNLGCPAQRFLQMLLQNDKKVLSFPLETPTL
THETFKALKPGLSAYADDVEKSAQGIQELLDVAKQDIPFDLWKATPLVLKATAGLRLLPGEKAQ
KLLQKVKEVFKASPFLVGDDCVSIMNGTDEGVSAWITVNFLTGSLRGPGRSSVGMLDLGGGSTQ
ITFLPRAEGTLEASPPGHLTSLQMFNRTYRLYSHSYLGLGLMSARLAILGGVEGRPAKDGKELV
SACLSPGFRGEWEHAEITYRISGQKAGRLHEPCASRVSEVLRNKVHRAEEAGHVDFYAFSYYYD
LAASVGLIDAEKGGSVTVEDFEIAAKYMCRTLGAQPHRSPFLCMDLTYVSLLLRELGFRGDKVL
KLTRKIDNVETSWALGAIFHYIDSLNRRKSTAW

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000015639	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000023015	ENTREZGENE
	ENSCLAT00000023015.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.420.40	UniProtKB/TrEMBL
	Exopolyphosphatase. Domain 2	UniProtKB/TrEMBL
InterPro	GDA1_CD39_NTPase	UniProtKB/TrEMBL
NCBI Gene	Entpd6	ENTREZGENE
PANTHER	ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 6	UniProtKB/TrEMBL
	PTHR11782	UniProtKB/TrEMBL
Pfam	GDA1_CD39	UniProtKB/TrEMBL
PROSITE	GDA1_CD39_NTPASE	UniProtKB/TrEMBL
UniProt	A0A8C2VZP5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-03-05	Entpd6	ectonucleoside triphosphate diphosphohydrolase 6		ectonucleoside triphosphate diphosphohydrolase 6 (putative)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD