Ddt (D-dopachrome tautomerase) - Rat Genome Database

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Gene: Ddt (D-dopachrome tautomerase) Rattus norvegicus
Analyze
Symbol: Ddt
Name: D-dopachrome tautomerase
RGD ID: 61923
Description: Enables D-dopachrome decarboxylase activity. Predicted to be involved in several processes, including negative regulation of macrophage chemotaxis; positive regulation of ERK1 and ERK2 cascade; and positive regulation of tumor necrosis factor production. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Orthologous to several human genes including DDT (D-dopachrome tautomerase); INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: D-dopachrome decarboxylase; dopachrome isomerase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,883,025 - 12,886,121 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.22012,884,216 - 12,886,687 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,884,243 - 12,888,482 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2013,590,792 - 13,593,263 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,951,735 - 12,954,206 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,424,018 - 13,426,496 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd2013,204,303 - 13,206,781 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive2014,200,164 - 14,202,642 (+)NCBILyon_Normotensive
Lyon_Hypertensive2014,203,296 - 14,205,774 (+)NCBILyon_Hypertensive
F344_StmMcwi2013,213,103 - 13,215,581 (+)NCBIF344_StmMcwi
Rnor_6.02013,827,153 - 13,829,624 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,827,132 - 13,831,588 (+)Ensemblrn6Rnor6.0
Rnor_5.02016,016,838 - 16,019,309 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42013,591,785 - 13,594,256 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2014,375,891 - 14,378,362 (+)NCBICelera
RGSC_v3.12013,592,013 - 13,594,480 (-)NCBI
Cytogenetic Map20p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3',5'-cyclic AMP  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bromobenzene  (EXP)
cadmium dichloride  (EXP)
cannabidiol  (ISO)
carbamazepine  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fructose  (EXP)
fumonisin B1  (ISO)
hydralazine  (ISO)
hydrazine  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
lovastatin  (ISO)
methamphetamine  (EXP)
methyl methanesulfonate  (ISO)
N-nitrosomorpholine  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
okadaic acid  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorododecanoic acid  (EXP)
pirinixic acid  (ISO)
progesterone  (EXP)
rotenone  (EXP)
sodium arsenite  (EXP)
sodium fluoride  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
tungsten  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,TAS)
extracellular space  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes. Hinojos CA, etal., Hypertension 2005 Apr;45(4):698-704. Epub 2005 Feb 14.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Isolation of a new tautomerase monitored by the conversion of D-dopachrome to 5,6-dihydroxyindole. Odh G, etal., Biochem Biophys Res Commun. 1993 Dec 15;197(2):619-24. doi: 10.1006/bbrc.1993.2524.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
8. NMR characterization of physicochemical properties of rat D-dopachrome tautomerase. Yoshida H, etal., Biochem Mol Biol Int 1997 Aug;42(5):891-9.
9. Cloning and sequencing of a cDNA encoding rat D-dopachrome tautomerase. Zhang M, etal., FEBS Lett 1995 Oct 16;373(3):203-6.
Additional References at PubMed
PMID:19056867   PMID:21817065   PMID:23376485   PMID:23533145   PMID:34116703  


Genomics

Comparative Map Data
Ddt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,883,025 - 12,886,121 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.22012,884,216 - 12,886,687 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,884,243 - 12,888,482 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2013,590,792 - 13,593,263 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,951,735 - 12,954,206 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,424,018 - 13,426,496 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd2013,204,303 - 13,206,781 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive2014,200,164 - 14,202,642 (+)NCBILyon_Normotensive
Lyon_Hypertensive2014,203,296 - 14,205,774 (+)NCBILyon_Hypertensive
F344_StmMcwi2013,213,103 - 13,215,581 (+)NCBIF344_StmMcwi
Rnor_6.02013,827,153 - 13,829,624 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,827,132 - 13,831,588 (+)Ensemblrn6Rnor6.0
Rnor_5.02016,016,838 - 16,019,309 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42013,591,785 - 13,594,256 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2014,375,891 - 14,378,362 (+)NCBICelera
RGSC_v3.12013,592,013 - 13,594,480 (-)NCBI
Cytogenetic Map20p12NCBI
DDT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,971,370 - 23,980,504 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,970,542 - 23,980,525 (-)Ensemblhg38GRCh38
GRCh372224,313,559 - 24,322,695 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,643,554 - 22,652,019 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342222,638,114 - 22,646,573NCBI
Celera228,114,132 - 8,122,585 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef227,261,709 - 7,270,163 (-)NCBIHuRef
CHM1_12224,326,074 - 24,334,537 (-)NCBICHM1_1
T2T-CHM13v2.02224,378,787 - 24,387,911 (-)NCBIT2T-CHM13v2.0
Ddt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,607,067 - 75,609,208 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1075,607,064 - 75,609,248 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381075,771,233 - 75,773,374 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,771,230 - 75,773,414 (-)Ensemblmm10GRCm38
MGSCv371075,233,978 - 75,236,119 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361075,214,949 - 75,217,090 (-)NCBIMGSCv36mm8
Celera1076,816,014 - 76,818,155 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.58NCBI
Ddt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,479,587 - 10,481,478 (-)Ensembl
ChiLan1.0NW_00495545510,479,409 - 10,481,080 (-)NCBIChiLan1.0ChiLan1.0
LOC100991346
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12222,814,869 - 22,815,793 (-)NCBIPanPan1.1PanPan1.1panPan2
DDT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12628,520,189 - 28,522,539 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2627,594,091 - 27,596,448 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02629,924,321 - 29,926,680 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2629,924,392 - 29,926,643 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12628,008,355 - 28,010,711 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02627,624,962 - 27,627,316 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02628,614,196 - 28,616,556 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101963449
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118141,709,010 - 141,711,056 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366191,043,006 - 1,045,054 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,790,804 - 49,793,357 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11449,790,794 - 49,793,196 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,233,009 - 53,235,411 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103223037
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1197,077,812 - 7,081,065 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666100282,915 - 286,125 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474712,473,181 - 12,474,898 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ddt
12 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:95
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000001664
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804392029865039Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804392015089182Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
RH128155  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22012,882,322 - 12,882,515 (+)MAPPERmRatBN7.2
Rnor_6.02013,825,260 - 13,825,452NCBIRnor6.0
Rnor_5.02016,014,945 - 16,015,137UniSTSRnor5.0
RGSC_v3.42013,595,957 - 13,596,149UniSTSRGSC3.4
Celera2014,373,976 - 14,374,168UniSTS
Cytogenetic Map20p12UniSTS
RH142321  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22012,886,431 - 12,886,588 (+)MAPPERmRatBN7.2
Rnor_6.02013,829,369 - 13,829,525NCBIRnor6.0
Rnor_5.02016,019,054 - 16,019,210UniSTSRnor5.0
RGSC_v3.42013,591,884 - 13,592,040UniSTSRGSC3.4
Celera2014,378,107 - 14,378,263UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001664   ⟹   ENSRNOP00000001664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2013,827,132 - 13,829,626 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093131   ⟹   ENSRNOP00000076125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2013,827,660 - 13,831,588 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2013,827,493 - 13,829,624 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119257   ⟹   ENSRNOP00000079844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2012,884,243 - 12,888,482 (+)Ensembl
RefSeq Acc Id: NM_024131   ⟹   NP_077045
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,883,650 - 12,886,121 (+)NCBI
mRatBN7.22012,884,216 - 12,886,687 (+)NCBI
Dahl_SR_JrHsd2013,204,303 - 13,206,781 (+)NCBI
Lyon_Normotensive2014,200,164 - 14,202,642 (+)NCBI
Lyon_Hypertensive2014,203,296 - 14,205,774 (+)NCBI
F344_StmMcwi2013,213,103 - 13,215,581 (+)NCBI
Rnor_6.02013,827,153 - 13,829,624 (+)NCBI
Rnor_5.02016,016,838 - 16,019,309 (+)NCBI
RGSC_v3.42013,591,785 - 13,594,256 (-)RGD
Celera2014,375,891 - 14,378,362 (+)RGD
Sequence:
RefSeq Acc Id: XM_063278989   ⟹   XP_063135059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82012,883,025 - 12,886,121 (+)NCBI
Protein Sequences
Protein RefSeqs NP_077045 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135059 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA85429 (Get FASTA)   NCBI Sequence Viewer  
  CCP38009 (Get FASTA)   NCBI Sequence Viewer  
  EDL97190 (Get FASTA)   NCBI Sequence Viewer  
  EDL97191 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079844.1
  ENSRNOP00000107743
GenBank Protein P80254 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_077045   ⟸   NM_024131
- UniProtKB: P80254 (UniProtKB/Swiss-Prot),   A0A0F7RQJ6 (UniProtKB/TrEMBL),   A6JKH4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000076125   ⟸   ENSRNOT00000093131
Ensembl Acc Id: ENSRNOP00000001664   ⟸   ENSRNOT00000001664
Ensembl Acc Id: ENSRNOP00000079844   ⟸   ENSRNOT00000119257
RefSeq Acc Id: XP_063135059   ⟸   XM_063278989
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P80254-F1-model_v2 AlphaFold P80254 1-118 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701535
Promoter ID:EPDNEW_R12059
Type:initiation region
Name:Ddt_1
Description:D-dopachrome tautomerase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02013,827,132 - 13,827,192EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61923 AgrOrtholog
BioCyc Gene G2FUF-4157 BioCyc
Ensembl Genes ENSRNOG00000001239 Ensembl
  ENSRNOG00000068887 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000083406 ENTREZGENE
Ensembl Transcript ENSRNOT00000119257.1 UniProtKB/Swiss-Prot
  ENSRNOT00000151293 ENTREZGENE
Gene3D-CATH 3.30.429.10 UniProtKB/Swiss-Prot
InterPro Macrophage_inhib_fac UniProtKB/Swiss-Prot
  Macrophage_inhib_fac_CS UniProtKB/Swiss-Prot
  Tautomerase/MIF_sf UniProtKB/Swiss-Prot
KEGG Report rno:29318 UniProtKB/Swiss-Prot
NCBI Gene 29318 ENTREZGENE
PANTHER D-DOPACHROME DECARBOXYLASE UniProtKB/Swiss-Prot
  PTHR11954 UniProtKB/Swiss-Prot
Pfam MIF UniProtKB/Swiss-Prot
PhenoGen Ddt PhenoGen
PROSITE MIF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001239 RatGTEx
  ENSRNOG00000068887 RatGTEx
  ENSRNOG00000083406 RatGTEx
Superfamily-SCOP SSF55331 UniProtKB/Swiss-Prot
TIGR TC204729
UniProt A0A0F7RQJ6 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LB54_RAT UniProtKB/TrEMBL
  A6JKH4 ENTREZGENE, UniProtKB/TrEMBL
  DOPD_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ddt  D-dopachrome tautomerase      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expression is decreased 1.3 fold in SHR compared with WKY rats 1357414
gene_protein 118 amino acids 61570