Gabrr2 (gamma-aminobutyric acid type A receptor subunit rho 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Gabrr2 (gamma-aminobutyric acid type A receptor subunit rho 2) Rattus norvegicus
Analyze
Symbol: Gabrr2
Name: gamma-aminobutyric acid type A receptor subunit rho 2
RGD ID: 61902
Description: Enables GABA-A receptor activity; protein domain specific binding activity; and transmitter-gated monoatomic ion channel activity. Predicted to be involved in GABAergic synaptic transmission and chloride transmembrane transport. Predicted to act upstream of or within gamma-aminobutyric acid signaling pathway and visual perception. Is active in GABA-ergic synapse. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human GABRR2 (gamma-aminobutyric acid type A receptor subunit rho2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GABA(A) receptor subunit rho-2; GABA(C) receptor; GABAAR subunit rho-2; gamma-aminobutyric acid (GABA) A receptor, rho 2; gamma-aminobutyric acid (GABA) receptor, rho 2; gamma-aminobutyric acid (GABA-A) receptor subunit rho 2; gamma-aminobutyric acid (GABA-A) receptor, subunit rho 2; gamma-aminobutyric acid (GABA-C) receptor, subunit rho 2; gamma-aminobutyric acid A receptor, rho 2; gamma-aminobutyric acid receptor subunit rho-2; gamma-aminobutyric acid type A receptor rho 2 subunit
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8552,242,564 - 52,286,255 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl552,243,256 - 52,296,746 (+)EnsemblGRCr8
mRatBN7.2547,445,280 - 47,489,929 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,452,150 - 47,489,809 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx549,598,143 - 49,635,800 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0551,197,326 - 51,234,977 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0551,140,749 - 51,178,468 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0548,303,366 - 48,341,571 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl548,303,366 - 48,341,642 (+)Ensemblrn6Rnor6.0
Rnor_5.0552,888,136 - 52,924,364 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4549,349,963 - 49,387,218 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera546,209,552 - 46,246,823 (+)NCBICelera
RGSC_v3.1549,350,141 - 49,387,397 (+)NCBI
Cytogenetic Map5q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Evidence for a functional role of GABA receptors in the rat mature hippocampus. Alakuijala A, etal., Eur J Neurosci. 2006 Jan;23(2):514-20. doi: 10.1111/j.1460-9568.2005.04572.x.
2. ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2. Croci C, etal., J Biol Chem 2003 Feb 21;278(8):6128-35.
3. gamma-Aminobutyric acidA rho receptor subunits in the developing rat hippocampus. Didelon F, etal., J Neurosci Res 2002 Mar 15;67(6):739-44.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. Ma DQ, etal., Am J Hum Genet. 2005 Sep;77(3):377-88. Epub 2005 Jul 15.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Identification of GABAA receptor subunits in rat retina: cloning of the rat GABAA receptor rho 2-subunit cDNA. Ogurusu T, etal., J Neurochem 1995 Sep;65(3):964-8.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
13. Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block. Zhang D, etal., Proc Natl Acad Sci U S A 1995 Dec 5;92(25):11756-60.
Additional References at PubMed
PMID:12019334   PMID:12706246   PMID:15617751   PMID:18201822  


Genomics

Comparative Map Data
Gabrr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8552,242,564 - 52,286,255 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl552,243,256 - 52,296,746 (+)EnsemblGRCr8
mRatBN7.2547,445,280 - 47,489,929 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,452,150 - 47,489,809 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx549,598,143 - 49,635,800 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0551,197,326 - 51,234,977 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0551,140,749 - 51,178,468 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0548,303,366 - 48,341,571 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl548,303,366 - 48,341,642 (+)Ensemblrn6Rnor6.0
Rnor_5.0552,888,136 - 52,924,364 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4549,349,963 - 49,387,218 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera546,209,552 - 46,246,823 (+)NCBICelera
RGSC_v3.1549,350,141 - 49,387,397 (+)NCBI
Cytogenetic Map5q21NCBI
GABRR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38689,254,464 - 89,315,299 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl689,254,464 - 89,315,299 (-)Ensemblhg38GRCh38
GRCh37689,964,183 - 90,025,018 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36690,023,958 - 90,081,686 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34690,023,957 - 90,081,673NCBI
Celera690,385,736 - 90,443,478 (-)NCBICelera
Cytogenetic Map6q15ENTREZGENE
HuRef687,183,652 - 87,241,843 (-)NCBIHuRef
CHM1_1690,064,781 - 90,122,809 (-)NCBICHM1_1
T2T-CHM13v2.0690,463,740 - 90,524,560 (-)NCBIT2T-CHM13v2.0
Gabrr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39433,057,715 - 33,095,865 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl433,062,999 - 33,095,865 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38433,057,712 - 33,095,865 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl433,062,999 - 33,095,865 (+)Ensemblmm10GRCm38
MGSCv37433,150,087 - 33,182,840 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36433,391,725 - 33,424,478 (+)NCBIMGSCv36mm8
Celera432,803,825 - 32,840,866 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.64NCBI
GABRR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25109,328,376 - 109,390,399 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,228,568 - 107,290,403 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,123,527 - 87,185,547 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1690,398,602 - 90,459,596 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl690,401,811 - 90,459,468 (-)EnsemblpanPan2panpan1.1
GABRR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11248,492,607 - 48,537,961 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1248,431,379 - 48,538,037 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1248,298,970 - 48,344,788 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01249,300,885 - 49,346,708 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1249,236,816 - 49,346,733 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11248,616,699 - 48,663,008 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01248,515,291 - 48,561,811 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01248,708,571 - 48,754,457 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gabrr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494683,520,034 - 83,579,800 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365102,891,101 - 2,951,071 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365102,891,136 - 2,949,428 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl157,286,705 - 57,332,720 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1157,287,265 - 57,332,342 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,065,021 - 64,110,481 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABRR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11314,015,862 - 14,074,742 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1314,016,672 - 14,073,757 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040190,333,419 - 190,400,995 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabrr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247994,841,898 - 4,900,172 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247994,841,856 - 4,900,704 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Gabrr2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11109,947,711 - 109,984,300 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Gabrr2
445 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:29
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000009973
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 160 91 90 59 91 59 6 346 190 11 138 73 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000009973   ⟹   ENSRNOP00000009973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl552,248,493 - 52,286,255 (+)Ensembl
mRatBN7.2 Ensembl547,452,150 - 47,489,809 (+)Ensembl
Rnor_6.0 Ensembl548,303,366 - 48,341,571 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000081825   ⟹   ENSRNOP00000068931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl548,313,599 - 48,341,642 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000124482   ⟹   ENSRNOP00000102496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl552,251,324 - 52,286,255 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000129441   ⟹   ENSRNOP00000111362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl552,248,331 - 52,296,746 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000130265   ⟹   ENSRNOP00000110953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl552,248,331 - 52,286,255 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000143365   ⟹   ENSRNOP00000100510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl552,243,256 - 52,286,255 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155034   ⟹   ENSRNOP00000100074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl552,243,256 - 52,286,255 (+)Ensembl
RefSeq Acc Id: NM_017292   ⟹   NP_058988
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,248,478 - 52,286,135 (+)NCBI
mRatBN7.2547,452,150 - 47,489,809 (+)NCBI
Rnor_6.0548,303,366 - 48,341,571 (+)NCBI
Rnor_5.0552,888,136 - 52,924,364 (+)NCBI
RGSC_v3.4549,349,963 - 49,387,218 (+)RGD
Celera546,209,552 - 46,246,823 (+)RGD
Sequence:
RefSeq Acc Id: XM_008763611   ⟹   XP_008761833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,257,189 - 52,286,255 (+)NCBI
mRatBN7.2547,461,982 - 47,489,929 (+)NCBI
Rnor_6.0548,313,261 - 48,341,380 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109380   ⟹   XP_038965308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,242,564 - 52,286,255 (+)NCBI
mRatBN7.2547,445,280 - 47,489,618 (+)NCBI
RefSeq Acc Id: XM_039109381   ⟹   XP_038965309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,242,564 - 52,283,262 (+)NCBI
mRatBN7.2547,445,280 - 47,486,735 (+)NCBI
RefSeq Acc Id: XM_039109382   ⟹   XP_038965310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,242,564 - 52,286,255 (+)NCBI
mRatBN7.2547,445,280 - 47,489,618 (+)NCBI
RefSeq Acc Id: XM_039109383   ⟹   XP_038965311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,266,643 - 52,286,255 (+)NCBI
mRatBN7.2547,470,317 - 47,489,929 (+)NCBI
RefSeq Acc Id: XM_039109384   ⟹   XP_038965312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,242,564 - 52,274,977 (+)NCBI
mRatBN7.2547,445,280 - 47,478,651 (+)NCBI
RefSeq Acc Id: XM_039109385   ⟹   XP_038965313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,242,564 - 52,286,255 (+)NCBI
mRatBN7.2547,445,280 - 47,489,929 (+)NCBI
RefSeq Acc Id: XM_063287266   ⟹   XP_063143336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8552,260,567 - 52,286,255 (+)NCBI
RefSeq Acc Id: NP_058988   ⟸   NM_017292
- Peptide Label: precursor
- UniProtKB: P47742 (UniProtKB/Swiss-Prot),   A6IIK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761833   ⟸   XM_008763611
- Peptide Label: isoform X4
- UniProtKB: A6IIK8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068931   ⟸   ENSRNOT00000081825
Ensembl Acc Id: ENSRNOP00000009973   ⟸   ENSRNOT00000009973
RefSeq Acc Id: XP_038965313   ⟸   XM_039109385
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038965308   ⟸   XM_039109380
- Peptide Label: isoform X1
- UniProtKB: A6IIK8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965310   ⟸   XM_039109382
- Peptide Label: isoform X3
- UniProtKB: A6IIK8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965309   ⟸   XM_039109381
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965312   ⟸   XM_039109384
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038965311   ⟸   XM_039109383
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063143336   ⟸   XM_063287266
- Peptide Label: isoform X7
Ensembl Acc Id: ENSRNOP00000100510   ⟸   ENSRNOT00000143365
Ensembl Acc Id: ENSRNOP00000111362   ⟸   ENSRNOT00000129441
Ensembl Acc Id: ENSRNOP00000110953   ⟸   ENSRNOT00000130265
Ensembl Acc Id: ENSRNOP00000100074   ⟸   ENSRNOT00000155034
Ensembl Acc Id: ENSRNOP00000102496   ⟸   ENSRNOT00000124482
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47742-F1-model_v2 AlphaFold P47742 1-465 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61902 AgrOrtholog
BioCyc Gene G2FUF-41707 BioCyc
Ensembl Genes ENSRNOG00000007490 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009973.4 UniProtKB/Swiss-Prot
  ENSRNOT00000130265 ENTREZGENE
  ENSRNOT00000155034 ENTREZGENE
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot
  2.70.170.10 UniProtKB/Swiss-Prot
InterPro GABAA/Glycine_rcpt UniProtKB/Swiss-Prot
  GABAAa_rho2_rcpt UniProtKB/Swiss-Prot
  GABAAa_rho_rcpt UniProtKB/Swiss-Prot
  Neur_chan_lig-bd UniProtKB/Swiss-Prot
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot
  Neur_channel UniProtKB/Swiss-Prot
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot
  Neuro_actylchol_rec UniProtKB/Swiss-Prot
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot
KEGG Report rno:29695 UniProtKB/Swiss-Prot
NCBI Gene 29695 ENTREZGENE
PANTHER PTHR18945 UniProtKB/Swiss-Prot
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot
  Neur_chan_memb UniProtKB/Swiss-Prot
PhenoGen Gabrr2 PhenoGen
PRINTS GABAARECEPTR UniProtKB/Swiss-Prot
  GABAARRHO UniProtKB/Swiss-Prot
  GABAARRHO2 UniProtKB/Swiss-Prot
  NRIONCHANNEL UniProtKB/Swiss-Prot
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007490 RatGTEx
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot
  SSF90112 UniProtKB/Swiss-Prot
TIGR TC215093
UniProt A0ABK0KZ31_RAT UniProtKB/TrEMBL
  A0ABK0LA83_RAT UniProtKB/TrEMBL
  A0ABK0LGB0_RAT UniProtKB/TrEMBL
  A0ABK0M4C7_RAT UniProtKB/TrEMBL
  A6IIK8 ENTREZGENE, UniProtKB/TrEMBL
  GBRR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Gabrr2  gamma-aminobutyric acid type A receptor subunit rho 2  Gabrr2  gamma-aminobutyric acid type A receptor rho 2 subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-11 Gabrr2  gamma-aminobutyric acid type A receptor rho 2 subunit  Gabrr2  gamma-aminobutyric acid (GABA) A receptor, rho 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-16 Gabrr2  gamma-aminobutyric acid (GABA) A receptor, rho 2  Gabrr2  gamma-aminobutyric acid (GABA) receptor, rho 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Gabrr2  gamma-aminobutyric acid (GABA) receptor, rho 2  Gabrr2  gamma-aminobutyric acid (GABA-C) receptor, subunit rho 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Gabrr2  gamma-aminobutyric acid (GABA-C) receptor, subunit rho 2    gamma-aminobutyric acid A receptor, rho 2  Name updated 1299863 APPROVED
2002-06-10 Gabrr2  gamma-aminobutyric acid A receptor, rho 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference