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Gene: Slc28a2 (solute carrier family 28 member 2) Rattus norvegicus

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Symbol:

Slc28a2

Name:

solute carrier family 28 member 2

RGD ID:

61840

Description:

Enables nucleoside:sodium symporter activity. Involved in protein localization to cell surface and retina homeostasis. Located in coated vesicle; plasma membrane; and vesicle membrane. Orthologous to human SLC28A2 (solute carrier family 28 member 2); PARTICIPATES IN azathioprine pharmacodynamics pathway; mercaptopurine pharmacodynamics pathway; mercaptopurine pharmacokinetics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CNT 2; concentrative nucleoside transporter 2; LOC102556085; Na(+)/nucleoside cotransporter 2; rCNT2; sodium-coupled nucleoside transporter 2; sodium/nucleoside cotransporter 2; sodium/nucleoside cotransporter 2-like; sodium/purine nucleoside cotransporter; solute carrier family 28 (concentrative nucleoside transporter), member 2; solute carrier family 28 (sodium-coupled nucleoside transporter) member 2; solute carrier family 28 (sodium-coupled nucleoside transporter), member 2; solute carrier family 28, member 2; SPNT

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC28A2 (solute carrier family 28 member 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Slc28a2 (solute carrier family 28 (sodium-coupled nucleoside transporter), member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc28a2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC28A2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc28a2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC28A2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC28A2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc28a2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SLC28A1 (solute carrier family 28 member 1)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Slc28a2 (solute carrier family 28 (sodium-coupled nucleoside transporter), member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC28A2 (solute carrier family 28 member 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc28a2b (solute carrier family 28 member 2b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	slc28a1 (solute carrier family 28 member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	slc-28.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CNT1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CNT2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	slc-28.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc28a2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	129,778,425 - 129,841,292 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	129,807,537 - 129,841,291 (+)	Ensembl				GRCr8
mRatBN7.2	3	109,324,815 - 109,387,702 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	109,366,996 - 109,387,702 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	113,039,238 - 113,060,743 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	121,634,754 - 121,656,259 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	119,295,132 - 119,316,637 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	114,355,003 - 114,647,382 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	114,355,798 - 114,647,382 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	120,897,082 - 120,921,371 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	109,350,531 - 109,372,027 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	108,262,866 - 108,284,103 (+)	NCBI		Celera
RGSC_v3.1	3	109,256,103 - 109,277,600 (-)	NCBI
Cytogenetic Map	3	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Diabetes Mellitus (IDA)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aconitine (EXP)

acrylamide (EXP)

adenosine (ISO)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

bromuconazole (EXP)

buspirone (EXP)

buta-1,3-diene (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

clofibrate (EXP)

clofibric acid (EXP)

cobalt dichloride (EXP)

coumarin (EXP)

D-penicillamine (EXP)

decabromodiphenyl ether (EXP)

dexamethasone (EXP)

dimethylarsinic acid (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

flutamide (EXP)

genistein (EXP)

gentamycin (EXP)

glyphosate (EXP)

indole-3-methanol (EXP)

leflunomide (EXP)

methimazole (EXP)

methylarsonic acid (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

nefazodone (EXP)

nimesulide (EXP)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paclitaxel (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorooctanoic acid (EXP)

permethrin (EXP)

phenobarbital (EXP)

pirinixic acid (EXP,ISO)

pregnenolone 16alpha-carbonitrile (EXP)

resveratrol (ISO)

rotenone (EXP)

sevoflurane (EXP)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium atom (ISO)

sodium dichromate (EXP,ISO)

succimer (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

toluene (EXP)

topotecan (EXP)

tributylstannane (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

uridine (ISO)

ursodeoxycholic acid (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenosine transport (ISO)

inosine transport (ISO)

neurotransmitter transport (ISO)

nucleoside transmembrane transport (IBA,IEA,ISO)

protein localization to cell surface (IDA)

purine nucleobase transmembrane transport (ISO)

purine nucleoside transmembrane transport (ISO)

pyrimidine nucleobase transport (IEA)

pyrimidine-containing compound transmembrane transport (ISO)

retina homeostasis (IBA,IDA)

uridine transmembrane transport (ISO)

Cellular Component

apicolateral plasma membrane (IEA,ISO,ISS)

brush border membrane (ISO)

coated vesicle (IDA)

membrane (IEA)

plasma membrane (IBA,IDA,IEA)

vesicle membrane (IDA)

Molecular Function

neurotransmitter transmembrane transporter activity (ISO)

nucleoside transmembrane transporter activity (IDA,IEA)

nucleoside:sodium symporter activity (IBA,IDA,ISO)

purine nucleobase transmembrane transporter activity (ISO)

purine nucleoside transmembrane transporter activity (IBA,ISO)

pyrimidine- and adenosine-specific:sodium symporter activity (ISO)

uridine transmembrane transporter activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

azathioprine pharmacodynamics pathway (ISO)

mercaptopurine pharmacodynamics pathway (ISO)

mercaptopurine pharmacokinetics pathway (ISO)

tioguanine pharmacodynamics pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Demonstration of the existence of mRNAs encoding N1/cif and N2/cit sodium/nucleoside cotransporters in rat brain.	Anderson CM, etal., Brain Res Mol Brain Res 1996 Dec;42(2):358-61.
2.	Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter.	Che M, etal., J Biol Chem 1995 Jun 9;270(23):13596-9.
3.	Bile acids alter the subcellular localization of CNT2 (concentrative nucleoside cotransporter) and increase CNT2-related transport activity in liver parenchymal cells.	Fernandez-Veledo S, etal., Biochem J. 2006 Apr 15;395(2):337-44.
4.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
6.	Characterization of the rat Na+/nucleoside cotransporter 2 and transport of nucleoside-derived drugs using electrophysiological methods.	Larrayoz IM, etal., Am J Physiol Cell Physiol. 2006 Dec;291(6):C1395-404. Epub 2006 Jul 12.
7.	Cloned blood-brain barrier adenosine transporter is identical to the rat concentrative Na+ nucleoside cotransporter CNT2.	Li JY, etal., J Cereb Blood Flow Metab 2001 Aug;21(8):929-36.
8.	Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum.	Melani A, etal., Exp Neurol. 2012 Jan;233(1):193-204. doi: 10.1016/j.expneurol.2011.09.036. Epub 2011 Oct 6.
9.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
10.	Study on intestinal absorption sites of mizoribine and ribavirin, substrates for concentrative nucleoside transporter(s), in rats.	Mori N, etal., Eur J Pharmacol. 2010 Feb 25;628(1-3):214-9. Epub 2009 Dec 2.
11.	Functional and molecular characterization of adenosine transport at the rat inner blood-retinal barrier.	Nagase K, etal., Biochim Biophys Acta. 2006 Jan;1758(1):13-9. Epub 2006 Feb 2.
12.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
14.	GOA pipeline	RGD automated data pipeline
15.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
17.	Expression of concentrative nucleoside transporters SLC28 (CNT1, CNT2, and CNT3) along the rat nephron: effect of diabetes.	Rodriguez-Mulero S, etal., Kidney Int. 2005 Aug;68(2):665-72.
18.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
19.	Transport of adenosine by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from rat jejunum expressed in Xenopus laevis oocytes.	Yao SY, etal., Mol Pharmacol 1996 Dec;50(6):1529-35.

Additional References at PubMed

PMID:1315767	PMID:10721696	PMID:15024061	PMID:15287894	PMID:16840788	PMID:17013559	PMID:20421393	PMID:22136384	PMID:22354287	PMID:23819782	PMID:25315414	PMID:28322028

Genomics

Comparative Map Data

Slc28a2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	129,778,425 - 129,841,292 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	129,807,537 - 129,841,291 (+)	Ensembl				GRCr8
mRatBN7.2	3	109,324,815 - 109,387,702 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	109,366,996 - 109,387,702 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	113,039,238 - 113,060,743 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	121,634,754 - 121,656,259 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	119,295,132 - 119,316,637 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	114,355,003 - 114,647,382 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	114,355,798 - 114,647,382 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	120,897,082 - 120,921,371 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	109,350,531 - 109,372,027 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	108,262,866 - 108,284,103 (+)	NCBI		Celera
RGSC_v3.1	3	109,256,103 - 109,277,600 (-)	NCBI
Cytogenetic Map	3	q35	NCBI

SLC28A2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	45,252,234 - 45,277,846 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	45,252,234 - 45,277,846 (+)	Ensembl			hg38	GRCh38
GRCh37	15	45,544,432 - 45,570,044 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	43,331,726 - 43,355,425 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	15	43,331,725 - 43,355,425	NCBI
Celera	15	22,435,715 - 22,459,420 (+)	NCBI		Celera
Cytogenetic Map	15	q21.1	NCBI
HuRef	15	22,368,444 - 22,392,157 (+)	NCBI		HuRef
CHM1_1	15	45,662,894 - 45,686,614 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	43,060,158 - 43,086,086 (+)	NCBI		T2T-CHM13v2.0

Slc28a2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	122,256,836 - 122,291,633 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	122,256,958 - 122,291,618 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	122,426,357 - 122,461,152 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	122,426,477 - 122,461,137 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	122,252,213 - 122,286,866 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	122,117,918 - 122,152,571 (+)	NCBI		MGSCv36	mm8
Celera	2	123,576,831 - 123,613,534 (+)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	60.63	NCBI

Slc28a2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	8,144,304 - 8,175,360 (-)	Ensembl
ChiLan1.0	NW_004955409	8,145,723 - 8,175,256 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC28A2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	34,491,976 - 34,519,267 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	38,670,150 - 38,697,435 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	24,199,846 - 24,223,378 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	42,554,204 - 42,577,891 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	42,554,142 - 42,578,096 (+)	Ensembl			panPan2	panpan1.1

Slc28a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	90,088,338 - 90,119,863 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	7,937,490 - 7,967,568 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	7,937,490 - 7,967,568 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC28A2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	126,472,525 - 126,511,095 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	126,472,500 - 126,511,207 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	141,072,725 - 141,110,169 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC28A2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	37,927,200 - 37,956,729 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	103,107,096 - 103,134,707 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc28a2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	13,998,505 - 14,025,732 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624731	13,999,029 - 14,051,964 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc28a2
497 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	96
Count of miRNA genes:	87
Interacting mature miRNAs:	91
Transcripts:	ENSRNOT00000036435
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	96509147	141509147	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	129154923	182114333	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	136118980	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	122654702	136118980	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	116582412	136118980	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	85062224	136118980	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	85062224	136118980	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	104545086	149545086	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	81425008	141509147	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	70845569	136091483	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	93829559	138829559	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	112250810	157250810	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	101255536	134750886	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	96509147	141509147	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	117537367	162537367	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	125116475	170116475	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	110225882	155225882	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	90755164	141509147	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	122395989	167395989	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	125814931	139636791	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	110634702	155634702	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	116188400	161188400	Rat

Markers in Region

RH127610

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	109,534,736 - 109,534,918 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	114,379,146 - 114,379,328	NCBI	Rnor6.0
Rnor_5.0	3	120,920,944 - 120,921,126	UniSTS	Rnor5.0
RGSC_v3.4	3	109,199,517 - 109,199,698	UniSTS	RGSC3.4
RH 3.4 Map	3	954.4	UniSTS
Cytogenetic Map	3	q35	UniSTS

RH131217

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	109,387,372 - 109,387,564 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	114,647,053 - 114,647,244	NCBI	Rnor6.0
Rnor_5.0	3	121,185,952 - 121,186,143	UniSTS	Rnor5.0
RGSC_v3.4	3	109,350,669 - 109,350,860	UniSTS	RGSC3.4
Celera	3	108,476,193 - 108,476,389	UniSTS
Celera	3	108,283,774 - 108,283,965	UniSTS
RH 3.4 Map	3	953.5	UniSTS
Cytogenetic Map	3	q35	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005501974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB485922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY029302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU032627	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U25055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U66723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U67084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024658 ⟹ ENSRNOP00000024658

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	129,807,537 - 129,841,291 (+)	Ensembl
mRatBN7.2 Ensembl	3	109,366,996 - 109,387,702 (+)	Ensembl
Rnor_6.0 Ensembl	3	114,355,798 - 114,647,382 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000036435 ⟹ ENSRNOP00000034564

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	114,355,814 - 114,378,941 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083380

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	114,650,518 - 114,652,214 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000122082 ⟹ ENSRNOP00000110608

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	129,807,537 - 129,841,291 (+)	Ensembl

RefSeq Acc Id:

NM_031664 ⟹ NP_113852

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,819,788 - 129,841,292 (+)	NCBI
mRatBN7.2	3	109,366,196 - 109,387,702 (+)	NCBI
Rnor_6.0	3	114,355,003 - 114,647,382 (+)	NCBI
Rnor_5.0	3	120,897,082 - 120,921,371 (+)	NCBI
RGSC_v3.4	3	109,350,531 - 109,372,027 (-)	RGD
Celera	3	108,262,866 - 108,284,103 (+)	RGD

Sequence:

show sequence

CCACGCGTCCGGTCTTGCTGAAGGGAAACCTCCACTTCCTGCTTGTGAGAGTATTAATCCCTGC
TGCAGCTGTCCATCCCCACTGACATCAGACTCCAGTTTCTCCAGGATCCAGTGTGTTCTGAAGA
TCAGCAGCTCTCCCGGAGTCTTCAAGGCGCCAGATTTGGAAGTCTGAGGCATCTGGCTTTGTAA
CCTGAGCAGCTGCCAGGTTCCAGCCATTATCTGACTGGGCTGTGCGGACCCACCCAGCACATTC
AGAGGATAACAGGAGATGGCGAAGTCAGAGGGAAGAAAGTCTGCTTCCCAGGACACATCGGAGA
ATGGCATGGAGAACCCAGGCCTGGAGCTCATGGAAGTCGGAAACCTTGAGCAAGGCAAAACACT
GGAGGAAGTGACACAGGGACATAGCCTGAAGGATGGCTTGGGGCATTCCTCTCTCTGGAGGAGG
ATTCTTCAGCCCTTCACCAAGGCGAGAAGTTTCTATCAAAGACATGCTGGTTTATTCAAAAAGA
TCCTGCTTGGTCTCTTGTGTTTAGCGTATGCTGCCTACCTCCTGGCAGCTTGCATCCTGAACTT
CCGGAGGGCACTGGCCTTGTTTGTCATCACCTGCCTTGTCATCTTCATCCTGGCTTGCCACTTT
CTGAAAAAATTCTTTGCTAAAAAGTCAATAAGATGCTTGAAGCCCTTGAAAAACACCCGCCTGA
GACTTTGGCTTAAGAGGGTGTTCATGGGAGCCGCTGTTGTCGGCCTTATTCTCTGGCTGGCTCT
GGACACAGCTCAAAGGCCAGAGCAGCTGATCTCCTTTGCGGGAATCTGCATGTTCATCCTCATC
CTCTTTGCCTGCTCCAAACACCACAGTGCGGTGAGCTGGAGGACAGTGTTTTGGGGCCTGGGCC
TTCAGTTCGTCTTTGGGATTTTGGTCATCAGAACTGAACCTGGATTTAATGCATTTCAATGGCT
GGGAGATCAGATCCAGATTTTCCTGGCATATACTGTAGAAGGATCCAGTTTTGTTTTTGGTGAC
ACACTGGTCCAAAGTGTTTTTGCTTTTCAGTCTCTCCCAATCATTATTTTCTTCGGATGTGTGA
TGTCTATTCTCTACTACCTGGGCCTTGTGCAGTGGGTGATCCAGAAGATTGCCTGGTTCCTGCA
AATCACCATGGGTACCACAGCTGCAGAGACCCTGGCCGTGGCAGGAAACATCTTTGTGGGAATG
ACAGAGGCACCTCTGCTCATCCGTCCCTACCTTGCAGACATGACCCTCTCTGAAATCCATGCAG
TGATGACTGGAGGCTTTGCTACTATAGCAGGCACAGTGTTGGGAGCCTTCATATCCTTTGGGAT
TGATGCATCATCCTTGATTTCTGCCTCAGTGATGGCTGCCCCTTGTGCACTTGCCTTGTCCAAA
CTGGTATATCCAGAAGTAGAAGAGTCCAAGTTCAAGAGCAAGGAGGGAGTGAAGCTGCCTCGAG
GGGAAGAGAGGAATATTCTGGAAGCCGCGAGCAACGGAGCCACAGATGCCATAGCGCTTGTTGC
TAATGTTGCAGCCAACCTGATTGCCTTTCTGGCTGTATTGGCCTTCATCAATTCTACCCTTTCC
TGGCTGGGGGAAATGGTGGATATCCATGGACTCACTTTCCAGGTCATCTGCTCCTATGTCCTAA
GGCCAATGGTTTTCATGATGGGTGTACAGTGGGCAGACTGCCCATTGGTGGCTGAGATAGTGGG
AGTCAAATTCTTCATAAATGAATTTGTGGCCTATCAACAACTGTCTCAGTACAAGAACAAACGT
CTCTCTGGAGTCGAAGAGTGGATCAATGGCGAGAAACAGTGGATTTCTGTGAAGGCTGAAATCA
TTGCAACATTTTCTCTCTGTGGATTTGCCAATCTTACTTCCATAGGGATCACACTGGGAGGCTT
GACATCCATGGTTCCCCAACGGAAGAGTGACTTGTGCAAGCTTGTGGTCAGGGCCCTCTTCACA
GGTGCCTGTGTTTCCTTCATCAGTGCCTGTATGGCAGGAATCCTCTATGTTCCCAGAGGCGCTG
AAACTGACTGTGTCTCATTCTTAAACACAAATTTCACCAACAGAACCTATGAGACATATGTGTG
CTGCAGAGAGCTCTTCCAGAGTACTTTGCTGAATGGCACCAACATGCCTTCTTTCTCAGGCCCC
TGGCAAGACAAGGAGTCCAGCCTCAGGAATCTTGCTAAATGCTGTGACCTCTATACCAGCACTG
TGTGTGCCTGAGGCTGGTGGGGCCATTCCGTGACAGTTCTTATAGAACAGATTCATATTACCAA
ATACATGTTCATGTACTTAGGCTTATTCTCTGAGAACTGCACTAAACTCCACAAAATGAAAGTC
CTGATCTCACTGTGGCTCTGTATAAAAACCAGCATCCACCTTTCCACTGGCATGCCACATAGTA
GATGTGAAATTCATTATAGACCCTCTTGAGCCAAAGTATGGTGGGAATGTAGCTAAGGGGGAAA
TATGTGTGTGGTAAGTGCTAAGATGGAGATTCAACCCCTGGCCAGGGCCAGAGTGGGGAGAGTG
GGGAAATCCAAGTAGATGCTTAGATTTAACTTGGTGGTACACCCTGTGGTCACTTACCTGTAAG
CTCAGAGCTAAGGGGATTGCCTCAGATCCAAGGCAAGCCTGGCCCGAACCCTGAAGTCTTTCAC
AGAAGTGATAGAGTAGAGGCCATGTCCTTGGGCAGGGATGGAGGTGAGGGAATATATTTCTAAA
GTTATATGGGAAACACTTGTGAATACTTAATGATAACATATTTTTTATTGCCAAAGGTTGTATA
CTTAAAAACTCTTTTCATTTTCATACATTACTAAAAAGCTTTCTGTAATAAAGTGTTTTTATGT
A

hide sequence

RefSeq Acc Id:

XM_039105768 ⟹ XP_038961696

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,816,819 - 129,841,292 (+)	NCBI
mRatBN7.2	3	109,363,227 - 109,387,185 (+)	NCBI

RefSeq Acc Id:

XM_039105769 ⟹ XP_038961697

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,778,449 - 129,841,292 (+)	NCBI
mRatBN7.2	3	109,324,815 - 109,387,699 (+)	NCBI

RefSeq Acc Id:

XM_039105770 ⟹ XP_038961698

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,820,049 - 129,841,292 (+)	NCBI
mRatBN7.2	3	109,366,528 - 109,387,185 (+)	NCBI

RefSeq Acc Id:

XM_063284459 ⟹ XP_063140529

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,778,442 - 129,841,292 (+)	NCBI

RefSeq Acc Id:

XM_063284460 ⟹ XP_063140530

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,807,442 - 129,841,292 (+)	NCBI

RefSeq Acc Id:

XM_063284461 ⟹ XP_063140531

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,778,425 - 129,841,292 (+)	NCBI

RefSeq Acc Id:

XM_063284462 ⟹ XP_063140532

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,778,449 - 129,841,292 (+)	NCBI

RefSeq Acc Id:

XR_005501974

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,816,819 - 129,839,298 (+)	NCBI
mRatBN7.2	3	109,363,227 - 109,385,722 (+)	NCBI

RefSeq Acc Id:

XR_010064689

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,816,819 - 129,840,775 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_113852	(Get FASTA)	NCBI Sequence Viewer
	XP_038961696	(Get FASTA)	NCBI Sequence Viewer
	XP_038961697	(Get FASTA)	NCBI Sequence Viewer
	XP_038961698	(Get FASTA)	NCBI Sequence Viewer
	XP_063140529	(Get FASTA)	NCBI Sequence Viewer
	XP_063140530	(Get FASTA)	NCBI Sequence Viewer
	XP_063140531	(Get FASTA)	NCBI Sequence Viewer
	XP_063140532	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA80640	(Get FASTA)	NCBI Sequence Viewer
	AAD00159	(Get FASTA)	NCBI Sequence Viewer
	AAD00160	(Get FASTA)	NCBI Sequence Viewer
	AAK38150	(Get FASTA)	NCBI Sequence Viewer
	BAH58083	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024658
GenBank Protein	Q62773	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_113852 ⟸ NM_031664

- UniProtKB:

F1LN73 (UniProtKB/TrEMBL), Q91WW8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKSEGRKSASQDTSENGMENPGLELMEVGNLEQGKTLEEVTQGHSLKDGLGHSSLWRRILQPF
TKARSFYQRHAGLFKKILLGLLCLAYAAYLLAACILNFRRALALFVITCLVIFILACHFLKKFF
AKKSIRCLKPLKNTRLRLWLKRVFMGAAVVGLILWLALDTAQRPEQLISFAGICMFILILFACS
KHHSAVSWRTVFWGLGLQFVFGILVIRTEPGFNAFQWLGDQIQIFLAYTVEGSSFVFGDTLVQS
VFAFQSLPIIIFFGCVMSILYYLGLVQWVIQKIAWFLQITMGTTAAETLAVAGNIFVGMTEAPL
LIRPYLADMTLSEIHAVMTGGFATIAGTVLGAFISFGIDASSLISASVMAAPCALALSKLVYPE
VEESKFKSKEGVKLPRGEERNILEAASNGATDAIALVANVAANLIAFLAVLAFINSTLSWLGEM
VDIHGLTFQVICSYVLRPMVFMMGVQWADCPLVAEIVGVKFFINEFVAYQQLSQYKNKRLSGVE
EWINGEKQWISVKAEIIATFSLCGFANLTSIGITLGGLTSMVPQRKSDLCKLVVRALFTGACVS
FISACMAGILYVPRGAETDCVSFLNTNFTNRTYETYVCCRELFQSTLLNGTNMPSFSGPWQDKE
SSLRNLAKCCDLYTSTVCA

hide sequence

Ensembl Acc Id:

ENSRNOP00000024658 ⟸ ENSRNOT00000024658

Ensembl Acc Id:

ENSRNOP00000034564 ⟸ ENSRNOT00000036435

RefSeq Acc Id:	XP_038961697 ⟸ XM_039105769
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL), Q91WW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961696 ⟸ XM_039105768
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL), Q91WW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961698 ⟸ XM_039105770
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL), Q91WW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140531 ⟸ XM_063284461
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL), Q91WW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140529 ⟸ XM_063284459
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL), Q91WW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140532 ⟸ XM_063284462
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL), Q91WW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140530 ⟸ XM_063284460
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL), Q91WW8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000110608 ⟸ ENSRNOT00000122082

Protein Domains

Concentrative nucleoside transporter C-terminal Concentrative nucleoside transporter N-terminal Nucleoside transporter/FeoB GTPase Gate

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q62773-F1-model_v2	AlphaFold	Q62773	1-659	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692368

Promoter ID:

EPDNEW_R2893

Type:

single initiation site

Name:

Slc28a2_1

Description:

solute carrier family 28 member 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	114,355,796 - 114,355,856	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61840	AgrOrtholog
BioCyc Gene	G2FUF-48096	BioCyc
Ensembl Genes	ENSRNOG00000028668	Ensembl, ENTREZGENE
	ENSRNOG00000052651	Ensembl
Ensembl Transcript	ENSRNOT00000024658	ENTREZGENE
InterPro	C_nuclsd_transpt	UniProtKB/Swiss-Prot
	C_nuclsd_transpt_met_bac	UniProtKB/Swiss-Prot
	CNT_C_dom	UniProtKB/Swiss-Prot
	CNT_N_dom	UniProtKB/Swiss-Prot
	Gate_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:60423	UniProtKB/Swiss-Prot
NCBI Gene	60423	ENTREZGENE
PANTHER	PTHR10590	UniProtKB/Swiss-Prot
	PTHR10590:SF11	UniProtKB/Swiss-Prot
Pfam	Gate	UniProtKB/Swiss-Prot
	Nucleos_tra2_C	UniProtKB/Swiss-Prot
	Nucleos_tra2_N	UniProtKB/Swiss-Prot
PharmGKB	SLC28A2	RGD
PhenoGen	Slc28a2	PhenoGen
RatGTEx	ENSRNOG00000028668	RatGTEx
	ENSRNOG00000052651	RatGTEx
TIGR	TC230283
UniProt	A0ABK0M573_RAT	UniProtKB/TrEMBL
	C1PHX8_RAT	UniProtKB/TrEMBL
	F1LN73	ENTREZGENE, UniProtKB/TrEMBL
	Q62773	ENTREZGENE
	Q91WW8	ENTREZGENE, UniProtKB/TrEMBL
	S28A2_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	Q9QWI3	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Slc28a2	solute carrier family 28 member 2	LOC102556085	sodium/nucleoside cotransporter 2-like	Data merged from RGD:7516973	737654	PROVISIONAL
2016-02-24	Slc28a2	solute carrier family 28 member 2	Slc28a2	solute carrier family 28 (concentrative nucleoside transporter), member 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-07-25	Slc28a2	solute carrier family 28 (concentrative nucleoside transporter), member 2	Slc28a2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-12-17	LOC102556085	sodium/nucleoside cotransporter 2-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-09-10	Slc28a2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2		solute carrier family 28, member 2	Name updated	1299863	APPROVED
2002-06-10	Slc28a2	solute carrier family 28, member 2			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - SMPDB