Advanced Search (OLGA)

Gene: Kcnab2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2) Rattus norvegicus

Analyze

Symbol:

Kcnab2

Name:

potassium voltage-gated channel subfamily A regulatory beta subunit 2

RGD ID:

61828

Description:

Enables alcohol dehydrogenase (NADP+) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Involved in myoblast differentiation; regulation of potassium ion transmembrane transport; and regulation of protein localization to cell surface. Located in axon; cytoplasmic side of plasma membrane; and cytosol. Part of potassium channel complex. Is active in glutamatergic synapse and postsynaptic density membrane. Colocalizes with microtubule. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2); INTERACTS WITH 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

K(+) channel subunit beta-2; kv-beta-2; potassium channel, voltage gated shaker-related subfamily A regulatory beta subunit 2; potassium channel, voltage gated subfamily A regulatory beta subunit 2; potassium channel, voltage-gated shaker-related subfamily A regulatory beta subunit 2; potassium voltage gated channel, shaker related subfamily, beta member 2; potassium voltage-gated channel, shaker-related subfamily, beta member 2; voltage-gated potassium channel subunit beta-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	168,182,228 - 168,270,760 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	168,184,613 - 168,270,760 (-)	Ensembl				GRCr8
mRatBN7.2	5	162,899,511 - 162,988,057 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	162,901,896 - 162,988,243 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	165,605,037 - 165,691,160 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	167,426,639 - 167,512,761 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	167,388,842 - 167,474,968 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	169,570,327 - 169,658,875 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	169,572,517 - 169,658,875 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	173,123,990 - 173,212,638 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	169,624,099 - 169,710,725 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	161,132,556 - 161,217,754 (-)	NCBI		Celera
RGSC_v3.1	5	169,634,286 - 169,720,913 (-)	NCBI
RH 3.4 Map	5	1140.7	RGD
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 1p36 deletion syndrome (ISS)

epilepsy (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,4'-trichlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

calciol (ISO)

carmustine (ISO)

choline (ISO)

cisplatin (ISO)

Cuprizon (EXP)

dioxygen (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

etoposide (ISO)

folic acid (ISO)

fulvestrant (ISO)

gentamycin (EXP)

L-methionine (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

mitoxantrone (ISO)

N,N-diethyl-m-toluamide (EXP)

NADP zwitterion (EXP)

NADP(+) (EXP)

nickel atom (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP)

PCB138 (ISO)

permethrin (EXP)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

tamibarotene (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

thiram (ISO)

trichloroethene (EXP)

triclosan (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

trovafloxacin (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

hematopoietic progenitor cell differentiation (ISO)

monoatomic ion transport (IEA)

myoblast differentiation (IEA,IEP)

neuromuscular process (ISO)

potassium ion transmembrane transport (IEA)

potassium ion transport (IEA)

regulation of potassium ion transmembrane transport (IBA,IDA,IEA,ISO)

regulation of protein localization to cell surface (IMP)

transmembrane transport (IEA)

Cellular Component

axon (IDA,IEA,ISO)

axon initial segment (ISO)

axon terminus (ISO)

cytoplasm (IEA)

cytoplasmic side of plasma membrane (IDA)

cytoskeleton (IEA)

cytosol (IDA)

glutamatergic synapse (IDA,IMP)

juxtaparanode region of axon (IBA,IDA,IEA,ISO)

membrane (IEA,ISO)

microtubule (IDA)

neuron projection (IDA,IEA)

pinceau fiber (IDA)

plasma membrane (IEA)

postsynaptic density (ISO)

postsynaptic density membrane (IDA,IMP)

potassium channel complex (IDA)

synapse (IEA)

voltage-gated potassium channel complex (IBA,IEA,ISO)

Molecular Function

alcohol dehydrogenase (NADP+) activity (IBA,IDA)

methylglyoxal reductase (NADPH) (acetol producing) activity (IEA)

oxidoreductase activity (IEA)

potassium channel regulator activity (IBA,IDA,IEA,ISO)

protein binding (IPI,ISO)

protein-containing complex binding (IPI)

transmembrane transporter binding (IBA,IPI)

voltage-gated potassium channel activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Separable effects of human Kvbeta1.2 N- and C-termini on inactivation and expression of human Kv1.4.	Accili EA, etal., J Physiol. 1998 Oct 15;512 ( Pt 2):325-36.
2.	ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.	Croci C, etal., J Biol Chem 2003 Feb 21;278(8):6128-35.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2.	Gong J, etal., Science. 1999 Sep 3;285(5433):1565-9.
6.	Voltage-dependent K+ channel beta subunits in muscle: differential regulation during postnatal development and myogenesis.	Grande M, etal., J Cell Physiol. 2003 May;195(2):187-93.
7.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
8.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
9.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.	A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets.	Ovsepian SV, etal., J Physiol. 2013 Apr 1;591(Pt 7):1771-91. doi: 10.1113/jphysiol.2012.249706. Epub 2013 Jan 14.
11.	Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels.	Poliak S, etal., Neuron. 1999 Dec;24(4):1037-47.
12.	The Kvβ2 subunit of voltage-gated potassium channels is interacting with ProSAP2/Shank3 in the PSD.	Proepper C, etal., Neuroscience. 2014 Mar 7;261:133-43. doi: 10.1016/j.neuroscience.2013.10.045. Epub 2013 Nov 6.
13.	Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit.	Rettig J, etal., Nature 1994 May 26;369(6478):289-94.
14.	GOA pipeline	RGD automated data pipeline
15.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
17.	Voltage-gated K+ channel beta subunits: expression and distribution of Kv beta 1 and Kv beta 2 in adult rat brain.	Rhodes KJ, etal., J Neurosci. 1996 Aug 15;16(16):4846-60.
18.	Association and colocalization of the Kvbeta1 and Kvbeta2 beta-subunits with Kv1 alpha-subunits in mammalian brain K+ channel complexes.	Rhodes KJ, etal., J Neurosci. 1997 Nov 1;17(21):8246-58.
19.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
20.	Catalytic mechanism and substrate specificity of the beta-subunit of the voltage-gated potassium channel.	Tipparaju SM, etal., Biochemistry. 2008 Aug 26;47(34):8840-54. doi: 10.1021/bi800301b. Epub 2008 Aug 2.
21.	Cdk-mediated phosphorylation of the Kvbeta2 auxiliary subunit regulates Kv1 channel axonal targeting.	Vacher H, etal., J Cell Biol. 2011 Mar 7;192(5):813-24. doi: 10.1083/jcb.201007113. Epub 2011 Feb 28.

Additional References at PubMed

PMID:7649300	PMID:8608002	PMID:10884227	PMID:11086297	PMID:11825900	PMID:12963709	PMID:14569011	PMID:15062979	PMID:16002581	PMID:16079148	PMID:16569641	PMID:21296056
PMID:22871113	PMID:24029230	PMID:25066316

Genomics

Comparative Map Data

Kcnab2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	168,182,228 - 168,270,760 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	168,184,613 - 168,270,760 (-)	Ensembl				GRCr8
mRatBN7.2	5	162,899,511 - 162,988,057 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	162,901,896 - 162,988,243 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	165,605,037 - 165,691,160 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	167,426,639 - 167,512,761 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	167,388,842 - 167,474,968 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	169,570,327 - 169,658,875 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	169,572,517 - 169,658,875 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	173,123,990 - 173,212,638 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	169,624,099 - 169,710,725 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	161,132,556 - 161,217,754 (-)	NCBI		Celera
RGSC_v3.1	5	169,634,286 - 169,720,913 (-)	NCBI
RH 3.4 Map	5	1140.7	RGD
Cytogenetic Map	5	q36	NCBI

KCNAB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	5,992,676 - 6,101,180 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	5,990,927 - 6,101,193 (+)	Ensembl			hg38	GRCh38
GRCh37	1	6,052,736 - 6,161,240 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	6,008,967 - 6,083,110 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	6,020,645 - 6,094,789	NCBI
Celera	1	5,201,212 - 5,275,339 (+)	NCBI		Celera
Cytogenetic Map	1	p36.31	NCBI
HuRef	1	5,201,765 - 5,310,071 (+)	NCBI		HuRef
CHM1_1	1	6,041,041 - 6,149,632 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	5,518,502 - 5,626,866 (+)	NCBI		T2T-CHM13v2.0

Kcnab2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	152,475,201 - 152,561,991 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	152,475,199 - 152,562,367 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	152,390,744 - 152,477,549 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	152,390,742 - 152,477,910 (-)	Ensembl			mm10	GRCm38
MGSCv37	4	151,764,853 - 151,851,588 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	151,234,544 - 151,321,279 (-)	NCBI		MGSCv36	mm8
Celera	4	154,677,910 - 154,763,618 (-)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	83.08	NCBI

Kcnab2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	6,369,288 - 6,442,885 (-)	Ensembl
ChiLan1.0	NW_004955486	6,371,212 - 6,442,888 (-)	NCBI	ChiLan1.0	ChiLan1.0

KCNAB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	222,123,611 - 222,235,524 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	220,764,655 - 220,877,249 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	4,755,412 - 4,866,424 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	6,012,647 - 6,120,438 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	6,013,072 - 6,120,438 (+)	Ensembl			panPan2	panpan1.1

KCNAB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	59,936,432 - 60,021,945 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	59,936,528 - 60,021,957 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	59,947,614 - 60,032,655 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	60,152,884 - 60,238,334 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	60,152,939 - 60,237,934 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	60,152,983 - 60,238,041 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	60,019,378 - 60,104,720 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	60,420,808 - 60,506,161 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Kcnab2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	30,463,300 - 30,502,711 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936623	940,678 - 985,388 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936623	972,288 - 987,949 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KCNAB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	66,928,381 - 67,016,845 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	66,928,374 - 67,016,846 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	61,880,875 - 61,923,103 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KCNAB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	125,636,352 - 125,743,821 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	125,638,962 - 125,708,768 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666054	29,784,200 - 29,893,813 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kcnab2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	5,253,773 - 5,327,000 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624818	5,251,304 - 5,326,796 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Kcnab2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	8,264,059 - 8,352,622 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	94
Count of miRNA genes:	77
Interacting mature miRNAs:	82
Transcripts:	ENSRNOT00000015840
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	130249266	172190305	Rat
1354583	Despr3	Despair related QTL3	4.98	0.0002	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	5	132930505	172190305	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	141212838	172190305	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	149642129	171146538	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	131708216	172190305	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	160111176	171146538	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	133789363	172190305	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	134369199	172190305	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	136631198	172190305	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	156396728	172190305	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	133081618	172190305	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	138002522	170842766	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	133270647	172190305	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	156289283	171137955	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	160071170	172129029	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	141764300	172190305	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	133081618	172190305	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	133789363	172190305	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	148093485	172129029	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat

Markers in Region

RH94672

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	162,987,799 - 162,987,983 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	169,658,618 - 169,658,801	NCBI	Rnor6.0
Rnor_5.0	5	173,212,381 - 173,212,564	UniSTS	Rnor5.0
RGSC_v3.4	5	169,710,468 - 169,710,651	UniSTS	RGSC3.4
Celera	5	161,217,497 - 161,217,680	UniSTS
RH 3.4 Map	5	1140.7	UniSTS
Cytogenetic Map	5	q36	UniSTS

BE103035

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	162,982,322 - 162,982,473 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	169,653,141 - 169,653,291	NCBI	Rnor6.0
Rnor_5.0	5	173,206,904 - 173,207,054	UniSTS	Rnor5.0
RGSC_v3.4	5	169,704,991 - 169,705,141	UniSTS	RGSC3.4
Celera	5	161,212,020 - 161,212,170	UniSTS
RH 3.4 Map	5	1142.4	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH138171

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	5	168,184,634 - 168,185,328 (+)	Marker Load Pipeline
mRatBN7.2	5	162,901,917 - 162,902,611 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	169,572,734 - 169,573,427	NCBI	Rnor6.0
Rnor_5.0	5	173,126,397 - 173,127,090	UniSTS	Rnor5.0
RGSC_v3.4	5	169,624,121 - 169,624,814	UniSTS	RGSC3.4
Celera	5	161,132,578 - 161,133,271	UniSTS
RH 3.4 Map	5	1139.9	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001429742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_017304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109386	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109387	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC097926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X76724	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000015840 ⟹ ENSRNOP00000015840

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	168,184,613 - 168,270,760 (-)	Ensembl
mRatBN7.2 Ensembl	5	162,901,896 - 162,988,057 (-)	Ensembl
Rnor_6.0 Ensembl	5	169,572,712 - 169,658,875 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000087043 ⟹ ENSRNOP00000073699

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	168,184,613 - 168,224,870 (-)	Ensembl
mRatBN7.2 Ensembl	5	162,901,896 - 162,937,047 (-)	Ensembl
Rnor_6.0 Ensembl	5	169,572,517 - 169,630,340 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101700 ⟹ ENSRNOP00000085478

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	168,184,613 - 168,270,760 (-)	Ensembl
mRatBN7.2 Ensembl	5	162,901,896 - 162,988,243 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111948 ⟹ ENSRNOP00000082892

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	168,184,613 - 168,242,315 (-)	Ensembl
mRatBN7.2 Ensembl	5	162,902,068 - 162,959,485 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113173 ⟹ ENSRNOP00000081886

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	168,184,613 - 168,270,477 (-)	Ensembl
mRatBN7.2 Ensembl	5	162,901,896 - 162,988,243 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119416 ⟹ ENSRNOP00000096391

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	168,184,613 - 168,211,608 (-)	Ensembl
mRatBN7.2 Ensembl	5	162,901,896 - 162,928,901 (-)	Ensembl

RefSeq Acc Id:

NM_017304 ⟹ NP_059000

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,184,613 - 168,270,760 (-)	NCBI
mRatBN7.2	5	162,901,896 - 162,988,057 (-)	NCBI
Rnor_6.0	5	169,572,712 - 169,658,875 (-)	NCBI
Rnor_5.0	5	173,123,990 - 173,212,638 (-)	NCBI
RGSC_v3.4	5	169,624,099 - 169,710,725 (-)	RGD
Celera	5	161,132,556 - 161,217,754 (-)	RGD

Sequence:

show sequence

GTCTCGTGGATCCAGTGCTGGTCCAGGGGGTCGCCCAATCCGCCGCCACCCACGCGAGGAGTCC
CGACCTGAGGGATACCGCTCACTCAGCACAGAACCCGCCCCGCGTCACTTTTACGTCAAGGTAG
CGCGGCCAATGAGAGCCAGAGTTCAATGATTCTGACTCTACGCGCGCGGACCAATCGACGCATC
GGCGGGAGCTGCAGGATTTGCATGGACTCCGAAGGCCACTGCCAATGAGACTGTGACTGGCGTG
AATCATAGCCAATAATAGGATGCTAGGGGCGTGGCCGCGGGCGTCCCACGAGGTAAAGATGCTG
CGGGCGGAACCTGCCGGAGCAAGCGGGATTCGGGGGTGCTGAAGTCGCAAGGGCAGGGCGGGAA
GGAAGATCCGGAACGGGGCGTGGGATCCGGAGCTGGAGGCCCCCAGGATTTCCCCTCTGTGAAA
AGACACGCTGATCTAGATAAGTGAGGCCGGCCCCATGTATCCGGAATCAACCACGGGGTCTCCA
GCTCGACTCTCCCTGCGGCAGACAGGCTCCCCCGGGATGATCTACAGTACTCGGTATGGGAGTC
CCAAAAGACAGCTCCAGTTTTACAGGAATCTGGGCAAATCTGGCCTTCGGGTCTCCTGCCTGGG
GCTTGGAACATGGGTGACCTTCGGAGGCCAGATCACAGATGAGATGGCAGAGCACCTAATGACC
TTGGCCTATGACAATGGCATCAACCTGTTCGATACGGCGGAGGTCTACGCAGCTGGCAAGGCTG
AAGTGGTATTAGGGAACATCATTAAGAAGAAGGGGTGGAGACGGTCCAGCCTTGTCATCACCAC
CAAGATCTTCTGGGGCGGAAAGGCAGAGACCGAGAGAGGCCTTTCCCGGAAGCACATAATCGAA
GGACTGAAAGCTTCCCTGGAGAGGCTGCAGCTGGAGTACGTGGATGTGGTTTTTGCCAACCGCC
CAGACCCCAACACACCCATGGAAGAGACTGTGCGGGCCATGACCCATGTCATCAACCAAGGGAT
GGCCATGTACTGGGGCACATCACGCTGGAGCTCCATGGAGATCATGGAGGCCTACTCGGTGGCT
CGGCAGTTCAACCTGATCCCGCCCATCTGCGAGCAAGCGGAATACCACATGTTCCAGAGGGAGA
AGGTAGAGGTCCAGCTGCCAGAGCTGTTCCACAAGATAGGAGTAGGTGCCATGACCTGGTCCCC
TCTGGCCTGCGGCATTGTCTCAGGGAAGTATGACAGTGGCATCCCACCCTACTCCAGAGCCTCT
CTGAAGGGCTACCAGTGGTTGAAGGACAAGATCCTGAGTGAGGAGGGTCGCCGCCAGCAAGCCA
AACTGAAGGAACTGCAGGCCATTGCAGAGCGCCTAGGCTGCACCCTCCCACAGCTGGCCATAGC
CTGGTGCCTGAGGAACGAGGGCGTCAGCTCCGTGCTCCTGGGTGCTTCCAATGCAGAACAACTT
ATGGAGAACATTGGAGCAATACAGGTCCTTCCAAAATTGTCGTCCTCCATCGTCCACGAGATCG
ACAGCATTCTGGGCAATAAACCCTACAGCAAAAAGGACTATAGATCCTAAGTCA

hide sequence

RefSeq Acc Id:

XM_017593214 ⟹ XP_017448703

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,182,228 - 168,270,469 (-)	NCBI
mRatBN7.2	5	162,899,511 - 162,987,771 (-)	NCBI
Rnor_6.0	5	169,570,327 - 169,658,546 (-)	NCBI

Sequence:

show sequence

CCTGCCGGAGCAAGCGGGATTCGGGGGTGCTGAAGTCGCAAGGGCAGGGCGGGAAGGAAGATCC
GGAACGGGGCGTGGGATCCGGAGCTGGAGGCCCCCAGGATTTCCCCTCTGTGAAAAGACACGCT
GATCTAGATAAGTGAGGCCGGCCCCATGTATCCGGAATCAACCACGGGGTCTCCAGCTCGACTC
TCCCTGCGGCAGACAGGCTCCCCCGGGATGATCTACAGTACTCGGTATGGGAGTCCCAAAAGAC
AGCTCCAGTTTTACAGGAATCTGGGCAAATCTGGCCTTCGGGTCTCCTGCCTGGGGCTTGGAAC
ATGGGTGACCTTCGGAGGCCAGATCACAGATGAGATGGCAGAGCACCTAATGACCTTGGCCTAT
GACAATGGCATCAACCTGTTCGATACGGCGGAGGTCTACGCAGCTGGCAAGGCTGAAGTGGTAT
TAGGGAACATCATTAAGAAGAAGGGGTGGAGACGGTCCAGCCTTGTCATCACCACCAAGATCTT
CTGGGGCGGAAAGGCAGAGACCGAGAGAGGCCTTTCCCGGAAGCACATAATCGAAGGACTGAAA
GCTTCCCTGGAGAGGCTGCAGCTGGAGTACGTGGATGTGGTTTTTGCCAACCGCCCAGACCCCA
ACACACCCATGGAAGCAGGGGACCCATTTAGTTCCTTCAAGTCACGGACATTCATCATTGAAGA
GACTGTGCGGGCCATGACCCATGTCATCAACCAAGGGATGGCCATGTACTGGGGCACATCACGC
TGGAGCTCCATGGAGATCATGGAGGCCTACTCGGTGGCTCGGCAGTTCAACCTGATCCCGCCCA
TCTGCGAGCAAGCGGAATACCACATGTTCCAGAGGGAGAAGGTAGAGGTCCAGCTGCCAGAGCT
GTTCCACAAGATAGGAGTAGGTGCCATGACCTGGTCCCCTCTGGCCTGCGGCATTGTCTCAGGG
AAGTATGACAGTGGCATCCCACCCTACTCCAGAGCCTCTCTGAAGGGCTACCAGTGGTTGAAGG
ACAAGATCCTGAGTGAGGAGGGTCGCCGCCAGCAAGCCAAACTGAAGGAACTGCAGGCCATTGC
AGAGCGCCTAGGCTGCACCCTCCCACAGCTGGCCATAGCCTGGTGCCTGAGGAACGAGGGCGTC
AGCTCCGTGCTCCTGGGTGCTTCCAATGCAGAACAACTTATGGAGAACATTGGAGCAATACAGG
TCCTTCCAAAATTGTCGTCCTCCATCGTCCACGAGATCGACAGCATTCTGGGCAATAAACCCTA
CAGCAAAAAGGACTATAGATCCTAAGTCACCCCCCCGCCCCCCCCAGCTCCCCCAGCTCGGACA
GTTCCTGGTTCCCTCCTCGTCTCTCGTTCGCTCGCTTCTGCCGTTTCAAAGCCAAATTGCAGAG
TGTGGTTCACACCCAACGGGAAAACACCATGCCCAGACGTCACCGGGGATTGATCTCGTCACCG
GGGATTGATCTCGAGTCACCGCCCAACGCAGCCTGCCGCTTCCTCGCTGGATGCGACCCGACGG
GTGCCAGGGGATGGCATCAATTAGGGGCACATCCAGAGGCTCCCACCCAAGCCTGCCACCCCTG
CTTATCCCTCAAGAAGAAACACTTGCCCCCAGCCGTGGCCCTCCATCGAGATTCGAGAAGCCAT
GGCCGGGTGGAGGTCTAGTCCTCGGAGTGGCCAGGGCTGGCCTCTCTGCCAGGAACCCGTCTCA
GAAGAGGGGCGTGCACCCCTCTCCCAGAGCCCCTGGTTAGAGCAGGGCCTCCCTCTTTCCATGG
ACACCAGGCACTTTGTTCAGGGCTGGCCTGGGATCCCACTCTTCCCAGGCCTTGACCTGCCCCA
CGCACCCACTGGGCCTTGGCTGGGACTACCTAGCTGGCCCTCAGCCCCTCCCTTACCCTTGCTG
GCAGGGGCAGGGATCCCAGCTGGCTTTCCCAGCATCTTCTATCCTATGTGTGACATACAACTGC
CGAGCCCCCAACAGGGAAGCTCAGCAGGCTTGGATGGAGCCCATTGGAGTAAGCCTCTCAAGAC
AGACACTAGTGGACAAGTGTGGCAGCTGGCCCCACCGTAGGCAGGTGGCAGCAGGCTGGGCCCA
AACTTGCAAGACCATATTGCTCTCATAGACCTTCCTCTGATACCTCTGCTGTGCTGGGGGGGGG
GGGAGTGGGCTCACGACATGGGCTTTGCACACATGAAGCACTTAGAGCTCCCTAGGGCTTCCAT
ATTGCGAGCCAAGGGACCAAGGGAGCAGCAGCTCCAGTAACAGTCTCCGTGTTGTAAGAAAAGA
CCTCTCCCTAGGAAAATGGCTAGGACCACCCATTCCTTTCTGCATACCCTTATGCTGTCCTAGG
GCAGGATAGAGAGACAGAGAGTGGGAAGGATGGACACCCCCTTATTAGTGGGAGCTAGATGGAT
GTAGACGCCAGGAAGCCTACAGGTTTGGGCAGTGCATGCTGCCTGGAGGCCCAATCCCGTGGTC
TTATGATGCTCTAGGGGACAGGGTCCTACCCAGCTGGCTCCCCAGGAGACCCAAGTCTCCTGCC
CTGGACAGGTCGTGGCCAGCTCCCAGGCACAAGCCCTGGACCATAGTGCCATGGCTACCTTCTG
TAGCTGCTATTCCAAGGCTCCTCTCTGCCGCTCTTAAGGCTGGGCAGAGGTTAGGACTGGGGTA
AGGGGTAGGGTTATGGGGTAGAGACGGGAAGAAAAGCAGACAGGGTGAGTAGCTTCCTCTCACA
CGCAACCCCCCTGTAACCCCTGGGCTCTCAAACCTTCAATGCTCATAGCGCTGACCCCTGAGAC
CTCAGAAGCAGCCCTGCGGGTGTGGGGATGGAGGCCACTGGGCTCTGGTACTTCTATGTCTGAC
TAGAGCAGCCAGCTTCCCAGACAGGGCCCTGCAGTGGCCCGGCAGGAAGTGCCAGACCTGTCCA
CACAGCTGGCCTTGGCCCTGCTTGCTACGTGGGCCAGGCATTCAGGGATGCCCACAGTAGGAGC
CGCTGCCTGCCTGTGAACCACACCTCAGAGCTATCCTCCTGCTGGGCATGTGCAAGAGACAGGA
AAACAGGCCGTAGGGCTAAGGCCCACAGGAGCCCAGATGCAGACAACCTCCTGGAAGACATTTT
AGCCAAATGTTTCTGAGAGGTTTCCTTCCACACCCCCCTCTTGAAGCATTGGGGATTTGCATCT
TAAGCTTCTGTGGGGGTGGGGGGTGGAGGAGGAGGGACTTGGGAGGCCACAGAAGTTGATCAAG
TGCAGACAGCCTATAAATGGGAGCTTGTCCCGGGCCCTCAAAGGGTCTAAGGCTAGCCCCTCCC
TCCATGGCCTCTCCTTCCTTTAGTCCAACTGCCTGCTGGTCAGACCAAGCCAGCCTCTCTCCAC
CCTCTTGAAGTAGTCTGTCAGGCCTGGTGCAGGAGGAGGGCTATGTATAGGATCTGGCACATGG
AGCCCTGCTCCTGCTCATCCCAGACCCAGGGTCCTGAGGCACAGCAGGGCACCTGGGTGCCCGC
TCTGGCCGTGTACATAACGTGCTTTCTCTCCCCATTTTTTAACGAGCGTGGCTCCTCGCTAACT
GCACCCCACCAAGGCCGACCGCAAACGCCTCCAGCTTCCTGACAGACTCGGACCAAGGTGCGGC
CCGTATTTATGGAATGGCAAATAAAACCCAAGCCCTTTGGTCTCCA

hide sequence

RefSeq Acc Id:

XM_017593215 ⟹ XP_017448704

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,182,228 - 168,242,246 (-)	NCBI
mRatBN7.2	5	162,899,511 - 162,959,531 (-)	NCBI
Rnor_6.0	5	169,570,327 - 169,630,324 (-)	NCBI

Sequence:

show sequence

GGGCCCTGGCGCTCGCTGCACCAACTTCCTGTTGGGCCTGTGGTCCTTGGTGGCACGCAGTTCG
TCCTACAGTGACTCAGCCATCCACCCAACATGAGGAACGCGTCTCTTCTGCGGGTCCCGGTCCA
CAGCAGGATTTCCCCTCTGTGAAAAGACACGCTGATCTAGATAAGTGAGGCCGGCCCCATGTAT
CCGGAATCAACCACGGGGTCTCCAGCTCGACTCTCCCTGCGGCAGACAGGCTCCCCCGGGATGA
TCTACAGTACTCGGTATGGGAGTCCCAAAAGACAGCTCCAGTTTTACAGGAATCTGGGCAAATC
TGGCCTTCGGGTCTCCTGCCTGGGGCTTGGAACATGGGTGACCTTCGGAGGCCAGATCACAGAT
GAGATGGCAGAGCACCTAATGACCTTGGCCTATGACAATGGCATCAACCTGTTCGATACGGCGG
AGGTCTACGCAGCTGGCAAGGCTGAAGTGGTATTAGGGAACATCATTAAGAAGAAGGGGTGGAG
ACGGTCCAGCCTTGTCATCACCACCAAGATCTTCTGGGGCGGAAAGGCAGAGACCGAGAGAGGC
CTTTCCCGGAAGCACATAATCGAAGGACTGAAAGCTTCCCTGGAGAGGCTGCAGCTGGAGTACG
TGGATGTGGTTTTTGCCAACCGCCCAGACCCCAACACACCCATGGAAGCAGGGGACCCATTTAG
TTCCTTCAAGTCACGGACATTCATCATTGAAGAGACTGTGCGGGCCATGACCCATGTCATCAAC
CAAGGGATGGCCATGTACTGGGGCACATCACGCTGGAGCTCCATGGAGATCATGGAGGCCTACT
CGGTGGCTCGGCAGTTCAACCTGATCCCGCCCATCTGCGAGCAAGCGGAATACCACATGTTCCA
GAGGGAGAAGGTAGAGGTCCAGCTGCCAGAGCTGTTCCACAAGATAGGAGTAGGTGCCATGACC
TGGTCCCCTCTGGCCTGCGGCATTGTCTCAGGGAAGTATGACAGTGGCATCCCACCCTACTCCA
GAGCCTCTCTGAAGGGCTACCAGTGGTTGAAGGACAAGATCCTGAGTGAGGAGGGTCGCCGCCA
GCAAGCCAAACTGAAGGAACTGCAGGCCATTGCAGAGCGCCTAGGCTGCACCCTCCCACAGCTG
GCCATAGCCTGGTGCCTGAGGAACGAGGGCGTCAGCTCCGTGCTCCTGGGTGCTTCCAATGCAG
AACAACTTATGGAGAACATTGGAGCAATACAGGTCCTTCCAAAATTGTCGTCCTCCATCGTCCA
CGAGATCGACAGCATTCTGGGCAATAAACCCTACAGCAAAAAGGACTATAGATCCTAAGTCACC
CCCCCGCCCCCCCCAGCTCCCCCAGCTCGGACAGTTCCTGGTTCCCTCCTCGTCTCTCGTTCGC
TCGCTTCTGCCGTTTCAAAGCCAAATTGCAGAGTGTGGTTCACACCCAACGGGAAAACACCATG
CCCAGACGTCACCGGGGATTGATCTCGTCACCGGGGATTGATCTCGAGTCACCGCCCAACGCAG
CCTGCCGCTTCCTCGCTGGATGCGACCCGACGGGTGCCAGGGGATGGCATCAATTAGGGGCACA
TCCAGAGGCTCCCACCCAAGCCTGCCACCCCTGCTTATCCCTCAAGAAGAAACACTTGCCCCCA
GCCGTGGCCCTCCATCGAGATTCGAGAAGCCATGGCCGGGTGGAGGTCTAGTCCTCGGAGTGGC
CAGGGCTGGCCTCTCTGCCAGGAACCCGTCTCAGAAGAGGGGCGTGCACCCCTCTCCCAGAGCC
CCTGGTTAGAGCAGGGCCTCCCTCTTTCCATGGACACCAGGCACTTTGTTCAGGGCTGGCCTGG
GATCCCACTCTTCCCAGGCCTTGACCTGCCCCACGCACCCACTGGGCCTTGGCTGGGACTACCT
AGCTGGCCCTCAGCCCCTCCCTTACCCTTGCTGGCAGGGGCAGGGATCCCAGCTGGCTTTCCCA
GCATCTTCTATCCTATGTGTGACATACAACTGCCGAGCCCCCAACAGGGAAGCTCAGCAGGCTT
GGATGGAGCCCATTGGAGTAAGCCTCTCAAGACAGACACTAGTGGACAAGTGTGGCAGCTGGCC
CCACCGTAGGCAGGTGGCAGCAGGCTGGGCCCAAACTTGCAAGACCATATTGCTCTCATAGACC
TTCCTCTGATACCTCTGCTGTGCTGGGGGGGGGGGGAGTGGGCTCACGACATGGGCTTTGCACA
CATGAAGCACTTAGAGCTCCCTAGGGCTTCCATATTGCGAGCCAAGGGACCAAGGGAGCAGCAG
CTCCAGTAACAGTCTCCGTGTTGTAAGAAAAGACCTCTCCCTAGGAAAATGGCTAGGACCACCC
ATTCCTTTCTGCATACCCTTATGCTGTCCTAGGGCAGGATAGAGAGACAGAGAGTGGGAAGGAT
GGACACCCCCTTATTAGTGGGAGCTAGATGGATGTAGACGCCAGGAAGCCTACAGGTTTGGGCA
GTGCATGCTGCCTGGAGGCCCAATCCCGTGGTCTTATGATGCTCTAGGGGACAGGGTCCTACCC
AGCTGGCTCCCCAGGAGACCCAAGTCTCCTGCCCTGGACAGGTCGTGGCCAGCTCCCAGGCACA
AGCCCTGGACCATAGTGCCATGGCTACCTTCTGTAGCTGCTATTCCAAGGCTCCTCTCTGCCGC
TCTTAAGGCTGGGCAGAGGTTAGGACTGGGGTAAGGGGTAGGGTTATGGGGTAGAGACGGGAAG
AAAAGCAGACAGGGTGAGTAGCTTCCTCTCACACGCAACCCCCCTGTAACCCCTGGGCTCTCAA
ACCTTCAATGCTCATAGCGCTGACCCCTGAGACCTCAGAAGCAGCCCTGCGGGTGTGGGGATGG
AGGCCACTGGGCTCTGGTACTTCTATGTCTGACTAGAGCAGCCAGCTTCCCAGACAGGGCCCTG
CAGTGGCCCGGCAGGAAGTGCCAGACCTGTCCACACAGCTGGCCTTGGCCCTGCTTGCTACGTG
GGCCAGGCATTCAGGGATGCCCACAGTAGGAGCCGCTGCCTGCCTGTGAACCACACCTCAGAGC
TATCCTCCTGCTGGGCATGTGCAAGAGACAGGAAAACAGGCCGTAGGGCTAAGGCCCACAGGAG
CCCAGATGCAGACAACCTCCTGGAAGACATTTTAGCCAAATGTTTCTGAGAGGTTTCCTTCCAC
ACCCCCCTCTTGAAGCATTGGGGATTTGCATCTTAAGCTTCTGTGGGGGTGGGGGGTGGAGGAG
GAGGGACTTGGGAGGCCACAGAAGTTGATCAAGTGCAGACAGCCTATAAATGGGAGCTTGTCCC
GGGCCCTCAAAGGGTCTAAGGCTAGCCCCTCCCTCCATGGCCTCTCCTTCCTTTAGTCCAACTG
CCTGCTGGTCAGACCAAGCCAGCCTCTCTCCACCCTCTTGAAGTAGTCTGTCAGGCCTGGTGCA
GGAGGAGGGCTATGTATAGGATCTGGCACATGGAGCCCTGCTCCTGCTCATCCCAGACCCAGGG
TCCTGAGGCACAGCAGGGCACCTGGGTGCCCGCTCTGGCCGTGTACATAACGTGCTTTCTCTCC
CCATTTTTTAACGAGCGTGGCTCCTCGCTAACTGCACCCCACCAAGGCCGACCGCAAACGCCTC
CAGCTTCCTGACAGACTCGGACCAAGGTGCGGCCCGTATTTATGGAATGGCAAATAAAACCCAA
GCCCTTTGGTCTCCA

hide sequence

RefSeq Acc Id:

XM_039109386 ⟹ XP_038965314

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,182,228 - 168,270,466 (-)	NCBI
mRatBN7.2	5	162,899,511 - 162,987,758 (-)	NCBI

RefSeq Acc Id:

XM_063287267 ⟹ XP_063143337

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,182,228 - 168,242,246 (-)	NCBI

RefSeq Acc Id:

XM_063287268 ⟹ XP_063143338

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,182,228 - 168,242,246 (-)	NCBI

RefSeq Acc Id:

XM_063287269 ⟹ XP_063143339

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,182,228 - 168,242,246 (-)	NCBI

RefSeq Acc Id:

XM_063287270 ⟹ XP_063143340

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,182,228 - 168,242,246 (-)	NCBI

RefSeq Acc Id:

XM_063287271 ⟹ XP_063143341

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	168,182,228 - 168,213,319 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001416671	(Get FASTA)	NCBI Sequence Viewer
	NP_001416672	(Get FASTA)	NCBI Sequence Viewer
	NP_001416673	(Get FASTA)	NCBI Sequence Viewer
	NP_001416674	(Get FASTA)	NCBI Sequence Viewer
	NP_001416675	(Get FASTA)	NCBI Sequence Viewer
	NP_001416676	(Get FASTA)	NCBI Sequence Viewer
	NP_001416677	(Get FASTA)	NCBI Sequence Viewer
	NP_059000	(Get FASTA)	NCBI Sequence Viewer
	XP_017448703	(Get FASTA)	NCBI Sequence Viewer
	XP_017448704	(Get FASTA)	NCBI Sequence Viewer
	XP_038965314	(Get FASTA)	NCBI Sequence Viewer
	XP_063143337	(Get FASTA)	NCBI Sequence Viewer
	XP_063143338	(Get FASTA)	NCBI Sequence Viewer
	XP_063143339	(Get FASTA)	NCBI Sequence Viewer
	XP_063143340	(Get FASTA)	NCBI Sequence Viewer
	XP_063143341	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA54142	(Get FASTA)	NCBI Sequence Viewer
	EDL81236	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015840
	ENSRNOP00000081886
	ENSRNOP00000082892
	ENSRNOP00000085478
GenBank Protein	P62483	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_059000 ⟸ NM_017304

- UniProtKB:

P62483 (UniProtKB/Swiss-Prot), A6IUI6 (UniProtKB/TrEMBL), A0A8I5ZVX6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQI
TDEMAEHLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETE
RGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSS
MEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYD
SGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSV
LLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPYSKKDYRS

hide sequence

RefSeq Acc Id:

XP_017448703 ⟸ XM_017593214

- Peptide Label:

isoform X1

- Sequence:

show sequence

MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQI
TDEMAEHLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETE
RGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEAGDPFSSFKSRTFIIEETVRAMTHV
INQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGA
MTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLP
QLAIAWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPYSKKDYRS

hide sequence

RefSeq Acc Id:	XP_017448704 ⟸ XM_017593215
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2Q7L3 (UniProtKB/TrEMBL), A0A8I5ZVX6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQI TDEMAEHLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETE RGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEAGDPFSSFKSRTFIIEETVRAMTHV INQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGA MTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLP QLAIAWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPYSKKDYRS hide sequence

Ensembl Acc Id:

ENSRNOP00000073699 ⟸ ENSRNOT00000087043

Ensembl Acc Id:

ENSRNOP00000015840 ⟸ ENSRNOT00000015840

RefSeq Acc Id:	XP_038965314 ⟸ XM_039109386
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I5ZVX6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000082892 ⟸ ENSRNOT00000111948

Ensembl Acc Id:

ENSRNOP00000096391 ⟸ ENSRNOT00000119416

Ensembl Acc Id:

ENSRNOP00000081886 ⟸ ENSRNOT00000113173

Ensembl Acc Id:

ENSRNOP00000085478 ⟸ ENSRNOT00000101700

RefSeq Acc Id:	XP_063143340 ⟸ XM_063287270
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063143338 ⟸ XM_063287268
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5ZVX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063143339 ⟸ XM_063287269
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063143337 ⟸ XM_063287267
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZVX6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063143341 ⟸ XM_063287271
- Peptide Label:	isoform X7

Protein Domains

NADP-dependent oxidoreductase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P62483-F1-model_v2	AlphaFold	P62483	1-367	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694315

Promoter ID:

EPDNEW_R4830

Type:

multiple initiation site

Name:

Kcnab2_1

Description:

potassium voltage-gated channel subfamily A regulatory beta subunit2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	169,630,341 - 169,630,401	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61828	AgrOrtholog
BioCyc Gene	G2FUF-39004	BioCyc
Ensembl Genes	ENSRNOG00000011550	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000015840	ENTREZGENE
	ENSRNOT00000101700	ENTREZGENE
	ENSRNOT00000111948	ENTREZGENE
	ENSRNOT00000113173	ENTREZGENE
Gene3D-CATH	3.20.20.100	UniProtKB/Swiss-Prot
InterPro	K_chnl_volt-dep_bsu_KCNAB	UniProtKB/Swiss-Prot
	K_chnl_volt-dep_bsu_KCNAB-rel	UniProtKB/Swiss-Prot
	K_chnl_volt-dep_bsu_KCNAB2	UniProtKB/Swiss-Prot
	NADP_OxRdtase_dom	UniProtKB/Swiss-Prot
	NADP_OxRdtase_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:29738	UniProtKB/Swiss-Prot
NCBI Gene	29738	ENTREZGENE
PANTHER	PTHR43150	UniProtKB/Swiss-Prot
	VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-2	UniProtKB/Swiss-Prot
Pfam	Aldo_ket_red	UniProtKB/Swiss-Prot
PhenoGen	Kcnab2	PhenoGen
PRINTS	KCNAB2CHANEL	UniProtKB/Swiss-Prot
	KCNABCHANNEL	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000011550	RatGTEx
Superfamily-SCOP	SSF51430	UniProtKB/Swiss-Prot
TIGR	TC236448
UniProt	A0A0G2K670	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZVX6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZYT6_RAT	UniProtKB/TrEMBL
	A0A8I6APC7_RAT	UniProtKB/TrEMBL
	A0A8I6GCY0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2Q7L3	ENTREZGENE, UniProtKB/TrEMBL
	A6IUI6	ENTREZGENE, UniProtKB/TrEMBL
	KCAB2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	P97381	UniProtKB/Swiss-Prot
	Q60942	UniProtKB/Swiss-Prot
	Q64284	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-11	Kcnab2	potassium voltage-gated channel subfamily A regulatory beta subunit 2	Kcnab2	potassium channel, voltage gated subfamily A regulatory beta subunit 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-02	Kcnab2	potassium channel, voltage gated subfamily A regulatory beta subunit 2	Kcnab2	potassium channel, voltage-gated shaker-related subfamily A regulatory beta subunit 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-01-27	Kcnab2	potassium channel, voltage-gated shaker-related subfamily A regulatory beta subunit 2	Kcnab2	potassium channel, voltage gated shaker-related subfamily A regulatory beta subunit 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-01-26	Kcnab2	potassium channel, voltage gated shaker-related subfamily A regulatory beta subunit 2	Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2		potassium voltage gated channel, shaker related subfamily, beta member 2	Name updated	1299863	APPROVED
2002-06-10	Kcnab2	potassium voltage gated channel, shaker related subfamily, beta member 2			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in the nervous system	61642

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI