Ralgds (ral guanine nucleotide dissociation stimulator) - Rat Genome Database

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Gene: Ralgds (ral guanine nucleotide dissociation stimulator) Rattus norvegicus
Analyze
Symbol: Ralgds
Name: ral guanine nucleotide dissociation stimulator
RGD ID: 3533
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in brush border; cytosol; and nucleus. Predicted to be active in plasma membrane. Orthologous to human RALGDS (ral guanine nucleotide dissociation stimulator); PARTICIPATES IN ceramide signaling pathway; colorectal cancer pathway; pancreatic cancer pathway; INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102554500; ral guanine nucleotide dissociation stimulator-like; ral guanine nucleotide exchange factor; ralGEF; Rgds
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,237,644 - 32,278,045 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl332,237,786 - 32,278,045 (+)EnsemblGRCr8
mRatBN7.2311,839,686 - 11,880,059 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,839,416 - 11,880,059 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx314,931,722 - 14,952,349 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,516,673 - 23,537,304 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,771,127 - 21,791,756 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,090,134 - 7,130,548 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,109,920 - 7,130,548 (+)Ensemblrn6Rnor6.0
Rnor_5.0312,440,157 - 12,481,565 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.437,516,054 - 7,537,651 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera36,640,808 - 6,660,733 (+)NCBICelera
RGSC_v3.137,516,353 - 7,537,935 (+)NCBI
Cytogenetic Map3p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Allylamine  (EXP)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Bufotalin  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
choline  (ISO)
cisplatin  (ISO)
citalopram  (EXP)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
dibutyl phthalate  (ISO)
dichlorine  (EXP)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dimethylarsinic acid  (EXP)
doxorubicin  (ISO)
escitalopram  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (EXP)
gentamycin  (EXP)
hydralazine  (ISO)
indole-3-methanol  (EXP)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
okadaic acid  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
thioacetamide  (EXP)
tipifarnib  (EXP)
titanium dioxide  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
brush border  (ISO)
cytoplasm  (IEA)
cytosol  (ISO,TAS)
nucleus  (IEA,ISO)
plasma membrane  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase. Albright CF, etal., EMBO J 1993 Jan;12(1):339-47.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:7972015   PMID:9253406   PMID:12642511   PMID:22797597  


Genomics

Comparative Map Data
Ralgds
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,237,644 - 32,278,045 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl332,237,786 - 32,278,045 (+)EnsemblGRCr8
mRatBN7.2311,839,686 - 11,880,059 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,839,416 - 11,880,059 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx314,931,722 - 14,952,349 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,516,673 - 23,537,304 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,771,127 - 21,791,756 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,090,134 - 7,130,548 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,109,920 - 7,130,548 (+)Ensemblrn6Rnor6.0
Rnor_5.0312,440,157 - 12,481,565 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.437,516,054 - 7,537,651 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera36,640,808 - 6,660,733 (+)NCBICelera
RGSC_v3.137,516,353 - 7,537,935 (+)NCBI
Cytogenetic Map3p12NCBI
RALGDS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389133,097,722 - 133,149,210 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9133,097,719 - 133,149,334 (-)Ensemblhg38GRCh38
GRCh379135,973,109 - 136,024,597 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,962,928 - 135,014,409 (-)NCBIBuild 36Build 36hg18NCBI36
Build 349133,002,661 - 133,026,115NCBI
Celera9106,514,832 - 106,566,263 (-)NCBICelera
Cytogenetic Map9q34.13-q34.2NCBI
HuRef9105,466,726 - 105,500,074 (-)NCBIHuRef
CHM1_19136,123,741 - 136,174,957 (-)NCBICHM1_1
T2T-CHM13v2.09145,311,872 - 145,363,296 (-)NCBIT2T-CHM13v2.0
Ralgds
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39228,403,037 - 28,443,085 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl228,403,137 - 28,443,093 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38228,513,089 - 28,553,082 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,513,125 - 28,553,081 (+)Ensemblmm10GRCm38
MGSCv37228,368,687 - 28,408,602 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36228,335,340 - 28,375,079 (+)NCBIMGSCv36mm8
Celera228,217,341 - 28,257,258 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Ralgds
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555132,386,293 - 2,405,161 (-)Ensembl
ChiLan1.0NW_0049555132,386,293 - 2,405,161 (-)NCBIChiLan1.0ChiLan1.0
RALGDS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,207,048 - 6,258,030 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan196,209,384 - 6,260,367 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09104,218,338 - 104,269,322 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,832,924 - 132,847,200 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,832,924 - 132,865,901 (-)EnsemblpanPan2panpan1.1
RALGDS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1951,287,252 - 51,329,997 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,550,610 - 50,592,293 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0952,180,564 - 52,222,391 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,180,324 - 52,223,270 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1950,980,284 - 51,000,916 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,283,824 - 51,325,521 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,363,054 - 51,404,763 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ralgds
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947199,706,834 - 199,732,858 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648719,476,205 - 19,495,105 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648719,475,361 - 19,501,347 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGDS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,776,846 - 272,824,184 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11272,776,844 - 272,824,179 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,700,576 - 306,713,801 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGDS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1124,993,357 - 5,042,347 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl125,018,872 - 5,041,602 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607910,611,288 - 10,660,534 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralgds
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247603,338,424 - 3,376,864 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247603,338,398 - 3,376,631 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ralgds
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v158,124,219 - 8,144,237 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ralgds
256 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:94
Interacting mature miRNAs:120
Transcripts:ENSRNOT00000013809
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)33083238444921701Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000013809   ⟹   ENSRNOP00000013809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl332,257,417 - 32,278,045 (+)Ensembl
mRatBN7.2 Ensembl311,859,428 - 11,880,059 (+)Ensembl
Rnor_6.0 Ensembl37,109,920 - 7,130,548 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084092   ⟹   ENSRNOP00000074350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl332,249,918 - 32,278,045 (+)Ensembl
mRatBN7.2 Ensembl311,863,832 - 11,880,059 (+)Ensembl
Rnor_6.0 Ensembl37,109,920 - 7,130,532 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl34,988,097 - 4,989,205 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096803   ⟹   ENSRNOP00000087735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl332,237,786 - 32,278,033 (+)Ensembl
mRatBN7.2 Ensembl311,839,416 - 11,880,059 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103319   ⟹   ENSRNOP00000088988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl332,252,173 - 32,277,135 (+)Ensembl
mRatBN7.2 Ensembl311,854,184 - 11,879,149 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000142346   ⟹   ENSRNOP00000100430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl332,261,513 - 32,278,032 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000164313   ⟹   ENSRNOP00000111335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl332,246,749 - 32,278,045 (+)Ensembl
RefSeq Acc Id: NM_001416483   ⟹   NP_001403412
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,257,519 - 32,278,034 (+)NCBI
mRatBN7.2311,859,530 - 11,880,048 (+)NCBI
RefSeq Acc Id: NM_019250   ⟹   NP_062123
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,257,417 - 32,278,045 (+)NCBI
mRatBN7.2311,859,428 - 11,880,059 (+)NCBI
Rnor_6.037,109,920 - 7,130,548 (+)NCBI
Rnor_5.0312,440,157 - 12,481,565 (+)NCBI
RGSC_v3.437,516,054 - 7,537,651 (+)RGD
Celera36,640,808 - 6,660,733 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233751   ⟹   XP_006233813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,246,717 - 32,278,034 (+)NCBI
mRatBN7.2311,848,760 - 11,880,050 (+)NCBI
Rnor_6.037,096,774 - 7,130,539 (+)NCBI
Rnor_5.0312,440,157 - 12,481,565 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233752   ⟹   XP_006233814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,237,644 - 32,278,034 (+)NCBI
mRatBN7.2311,839,686 - 11,880,050 (+)NCBI
Rnor_6.037,090,134 - 7,130,539 (+)NCBI
Rnor_5.0312,440,157 - 12,481,565 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233753   ⟹   XP_006233815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,237,651 - 32,278,034 (+)NCBI
mRatBN7.2311,839,686 - 11,880,050 (+)NCBI
Rnor_6.037,090,134 - 7,130,539 (+)NCBI
Rnor_5.0312,440,157 - 12,481,565 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591589   ⟹   XP_017447078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,247,063 - 32,278,034 (+)NCBI
mRatBN7.2311,849,200 - 11,880,050 (+)NCBI
Rnor_6.037,099,610 - 7,130,539 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063283354   ⟹   XP_063139424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,246,735 - 32,278,034 (+)NCBI
RefSeq Acc Id: XM_063283357   ⟹   XP_063139427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,246,731 - 32,278,034 (+)NCBI
RefSeq Acc Id: NP_062123   ⟸   NM_019250
- Peptide Label: isoform 1
- UniProtKB: Q03386 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006233814   ⟸   XM_006233752
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A8C4 (UniProtKB/TrEMBL),   A0A0G2K7U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233815   ⟸   XM_006233753
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K7U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233813   ⟸   XM_006233751
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K7U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447078   ⟸   XM_017591589
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K7U4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074350   ⟸   ENSRNOT00000084092
Ensembl Acc Id: ENSRNOP00000013809   ⟸   ENSRNOT00000013809
Ensembl Acc Id: ENSRNOP00000088988   ⟸   ENSRNOT00000103319
Ensembl Acc Id: ENSRNOP00000087735   ⟸   ENSRNOT00000096803
RefSeq Acc Id: NP_001403412   ⟸   NM_001416483
- Peptide Label: isoform 2
- UniProtKB: Q03386 (UniProtKB/Swiss-Prot),   F1LN84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139427   ⟸   XM_063283357
- Peptide Label: isoform X6
- UniProtKB: A0A0G2K7U4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139424   ⟸   XM_063283354
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K7U4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100430   ⟸   ENSRNOT00000142346
Ensembl Acc Id: ENSRNOP00000111335   ⟸   ENSRNOT00000164313
Protein Domains
N-terminal Ras-GEF   Ras-associating   Ras-GEF

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q03386-F1-model_v2 AlphaFold Q03386 1-895 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691933
Promoter ID:EPDNEW_R2458
Type:single initiation site
Name:Ralgds_1
Description:ral guanine nucleotide dissociation stimulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.037,110,022 - 7,110,082EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3533 AgrOrtholog
BioCyc Gene G2FUF-50279 BioCyc
Ensembl Genes ENSRNOG00000010219 Ensembl, ENTREZGENE
  ENSRNOG00000053371 Ensembl
Ensembl Transcript ENSRNOT00000013809 ENTREZGENE
  ENSRNOT00000084092 ENTREZGENE
  ENSRNOT00000096803 ENTREZGENE
  ENSRNOT00000142346 ENTREZGENE
  ENSRNOT00000164313 ENTREZGENE
Gene3D-CATH 1.10.840.10 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
  Son of sevenless (SoS) protein Chain: S domain 1 UniProtKB/Swiss-Prot
InterPro RA_dom UniProtKB/Swiss-Prot
  RalGDS UniProtKB/Swiss-Prot
  Ras-like_GEF UniProtKB/Swiss-Prot
  Ras-like_Gua-exchang_fac_N UniProtKB/Swiss-Prot
  Ras_G-nucl-exch_fac_CS UniProtKB/Swiss-Prot
  Ras_GEF_dom_sf UniProtKB/Swiss-Prot
  RASGEF_cat_dom UniProtKB/Swiss-Prot
  RASGEF_cat_dom_sf UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report rno:29622 UniProtKB/Swiss-Prot
NCBI Gene 29622 ENTREZGENE
PANTHER PTHR23113 UniProtKB/Swiss-Prot
  PTHR23113:SF35 UniProtKB/Swiss-Prot
Pfam PF00788 UniProtKB/Swiss-Prot
  RasGEF UniProtKB/Swiss-Prot
  RasGEF_N UniProtKB/Swiss-Prot
PhenoGen Ralgds PhenoGen
PROSITE PS50200 UniProtKB/Swiss-Prot
  RASGEF UniProtKB/Swiss-Prot
  RASGEF_CAT UniProtKB/Swiss-Prot
  RASGEF_NTER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010219 RatGTEx
  ENSRNOG00000053371 RatGTEx
SMART RasGEF UniProtKB/Swiss-Prot
  RasGEFN UniProtKB/Swiss-Prot
  SM00314 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48366 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
TIGR TC217563
UniProt A0A0G2K7U4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7N2_RAT UniProtKB/TrEMBL
  A0A8I6A8C4 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LG16_RAT UniProtKB/TrEMBL
  A0ABK0M6J0_RAT UniProtKB/TrEMBL
  A6JTN7_RAT UniProtKB/TrEMBL
  F1LN84 ENTREZGENE, UniProtKB/TrEMBL
  GNDS_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ralgds  ral guanine nucleotide dissociation stimulator  LOC102554500  ral guanine nucleotide dissociation stimulator-like  Data merged from RGD:7684955 737654 PROVISIONAL
2013-12-18 LOC102554500  ral guanine nucleotide dissociation stimulator-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Ralgds  ral guanine nucleotide dissociation stimulator      Name updated 70584 APPROVED