Cela2a (chymotrypsin like elastase 2A) - Rat Genome Database

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Gene: Cela2a (chymotrypsin like elastase 2A) Rattus norvegicus
Analyze
Symbol: Cela2a
Name: chymotrypsin like elastase 2A
RGD ID: 2548
Description: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in several processes, including insulin catabolic process; regulation of insulin secretion; and regulation of platelet aggregation. Predicted to be located in extracellular region and keratohyalin granule. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in abdominal obesity-metabolic syndrome 4. Orthologous to several human genes including CELA2A (chymotrypsin like elastase 2A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: chymotrypsin-like elastase family member 2A; chymotrypsin-like elastase family, member 2A; Ela2; Ela2a; ELAII; Elaii1; elastase 2; Elastase 2 pancreatic; Elastase 2, pancreatic; elastase 2A; elastase-2; elastase-2A
RGD Orthologs
Human
Mouse
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,409,900 - 159,420,282 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5159,409,899 - 159,426,208 (-)EnsemblGRCr8
mRatBN7.25154,126,879 - 154,136,630 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5154,126,878 - 154,136,632 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5156,811,783 - 156,821,667 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,585,079 - 158,594,963 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,574,229 - 158,584,115 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd5159,023,306 - 159,033,191 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive5161,013,570 - 161,023,454 (-)NCBILyon_Normotensive
Lyon_Hypertensive5160,189,067 - 160,198,953 (-)NCBILyon_Hypertensive
F344_StmMcwi5153,757,856 - 153,767,740 (-)NCBIF344_StmMcwi
Rnor_6.05160,374,031 - 160,383,782 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,374,031 - 160,383,782 (-)Ensemblrn6Rnor6.0
Rnor_5.05164,085,554 - 164,106,135 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45160,722,053 - 160,731,804 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5152,478,974 - 152,488,731 (-)NCBICelera
RGSC_v3.15160,732,240 - 160,741,992 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Primary structure of two distinct rat pancreatic preproelastases determined by sequence analysis of the complete cloned messenger ribonucleic acid sequences. MacDonald RJ, etal., Biochemistry 1982 Mar 16;21(6):1453-63.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Molecular cloning and sequencing of the cDNA for rat mesenteric arterial bed elastase-2, an angiotensin II-forming enzyme. Santos CF, etal., J Cardiovasc Pharmacol 2002 May;39(5):628-35.
9. Structure of the two related elastase genes expressed in the rat pancreas. Swift GH, etal., J Biol Chem 1984 Nov 25;259(22):14271-8.
Additional References at PubMed
PMID:12714330   PMID:15644940   PMID:20179351   PMID:21602471   PMID:31358993  


Genomics

Comparative Map Data
Cela2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,409,900 - 159,420,282 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5159,409,899 - 159,426,208 (-)EnsemblGRCr8
mRatBN7.25154,126,879 - 154,136,630 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5154,126,878 - 154,136,632 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5156,811,783 - 156,821,667 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,585,079 - 158,594,963 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,574,229 - 158,584,115 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd5159,023,306 - 159,033,191 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive5161,013,570 - 161,023,454 (-)NCBILyon_Normotensive
Lyon_Hypertensive5160,189,067 - 160,198,953 (-)NCBILyon_Hypertensive
F344_StmMcwi5153,757,856 - 153,767,740 (-)NCBIF344_StmMcwi
Rnor_6.05160,374,031 - 160,383,782 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,374,031 - 160,383,782 (-)Ensemblrn6Rnor6.0
Rnor_5.05164,085,554 - 164,106,135 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45160,722,053 - 160,731,804 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5152,478,974 - 152,488,731 (-)NCBICelera
RGSC_v3.15160,732,240 - 160,741,992 (-)NCBI
Cytogenetic Map5q36NCBI
CELA2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,456,732 - 15,472,091 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,456,728 - 15,472,091 (+)Ensemblhg38GRCh38
GRCh37115,783,227 - 15,798,586 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,655,811 - 15,671,170 (+)NCBIBuild 36Build 36hg18NCBI36
Celera114,266,097 - 14,281,458 (+)NCBICelera
Cytogenetic Map1p36.21NCBI
HuRef114,303,023 - 14,318,355 (+)NCBIHuRef
CHM1_1115,581,888 - 15,597,250 (+)NCBICHM1_1
T2T-CHM13v2.0114,901,450 - 14,916,792 (+)NCBIT2T-CHM13v2.0
Cela2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,542,265 - 141,553,316 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,542,273 - 141,553,471 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384141,814,954 - 141,826,005 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,814,962 - 141,826,160 (-)Ensemblmm10GRCm38
MGSCv374141,370,878 - 141,381,918 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364141,087,039 - 141,098,079 (-)NCBIMGSCv36mm8
Celera4143,639,909 - 143,650,953 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map474.75NCBI
LOC100992916
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21211,451,372 - 211,473,090 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,699,826 - 210,721,553 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0114,595,218 - 14,606,322 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1115,589,914 - 15,604,924 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl115,589,878 - 15,604,926 (+)EnsemblpanPan2panpan1.1

Variants

.
Variants in Cela2a
18 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:26
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000018349
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5149805999162987697Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5156396728167181764Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat

Markers in Region
D5Arb14  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85159,420,190 - 159,420,447 (+)Marker Load Pipeline
mRatBN7.25154,137,169 - 154,137,426 (+)MAPPERmRatBN7.2
Rnor_6.05160,384,322 - 160,384,578NCBIRnor6.0
Rnor_5.05164,095,845 - 164,096,101UniSTSRnor5.0
RGSC_v3.45160,732,342 - 160,732,600RGDRGSC3.4
Celera5152,489,271 - 152,489,527UniSTS
RGSC_v3.15160,742,530 - 160,742,788RGD
FHH x ACI Map585.54UniSTS
FHH x ACI Map585.54RGD
Cytogenetic Map5q36UniSTS
RH142416  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25154,137,407 - 154,137,592 (+)MAPPERmRatBN7.2
Rnor_6.05160,384,560 - 160,384,744NCBIRnor6.0
Rnor_5.05164,096,083 - 164,096,267UniSTSRnor5.0
RGSC_v3.45160,732,582 - 160,732,766UniSTSRGSC3.4
Celera5152,489,509 - 152,489,693UniSTS
Cytogenetic Map5q36UniSTS
RH140695  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25154,130,449 - 154,131,766 (+)MAPPERmRatBN7.2
Rnor_6.05160,377,602 - 160,378,918NCBIRnor6.0
Rnor_5.05164,089,125 - 164,090,441UniSTSRnor5.0
RGSC_v3.45160,725,624 - 160,726,940UniSTSRGSC3.4
Celera5152,482,551 - 152,483,867UniSTS
RH 3.4 Map51057.3UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 20 72 80 79 48 36 48 4 157 75 54 17 58 31 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000018349   ⟹   ENSRNOP00000018349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,409,899 - 159,419,653 (-)Ensembl
mRatBN7.2 Ensembl5154,126,878 - 154,136,632 (-)Ensembl
Rnor_6.0 Ensembl5160,374,031 - 160,383,782 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000146859   ⟹   ENSRNOP00000100366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,409,899 - 159,426,208 (-)Ensembl
RefSeq Acc Id: NM_012553   ⟹   NP_036685
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,409,900 - 159,419,651 (-)NCBI
mRatBN7.25154,126,879 - 154,136,630 (-)NCBI
Dahl_SR_JrHsd5159,023,306 - 159,033,191 (-)NCBI
Lyon_Normotensive5161,013,570 - 161,023,454 (-)NCBI
Lyon_Hypertensive5160,189,067 - 160,198,953 (-)NCBI
F344_StmMcwi5153,757,856 - 153,767,740 (-)NCBI
Rnor_6.05160,374,031 - 160,383,782 (-)NCBI
Rnor_5.05164,085,554 - 164,106,135 (-)NCBI
RGSC_v3.45160,722,053 - 160,731,804 (-)RGD
Celera5152,478,974 - 152,488,731 (-)RGD
Sequence:
RefSeq Acc Id: XM_063287152   ⟹   XP_063143222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,410,811 - 159,420,282 (-)NCBI
Protein Sequences
Protein RefSeqs NP_036685 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143222 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA98780 (Get FASTA)   NCBI Sequence Viewer  
  CAA24543 (Get FASTA)   NCBI Sequence Viewer  
  EDL81019 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018349
  ENSRNOP00000018349.3
GenBank Protein P00774 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_036685   ⟸   NM_012553
- Peptide Label: precursor
- UniProtKB: P00774 (UniProtKB/Swiss-Prot),   A6ITW9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018349   ⟸   ENSRNOT00000018349
RefSeq Acc Id: XP_063143222   ⟸   XM_063287152
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000100366   ⟸   ENSRNOT00000146859
Protein Domains
Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P00774-F1-model_v2 AlphaFold P00774 1-271 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694235
Promoter ID:EPDNEW_R4760
Type:single initiation site
Name:Cela2a_1
Description:chymotrypsin-like elastase family, member 2A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05160,383,784 - 160,383,844EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2548 AgrOrtholog
BioCyc Gene G2FUF-39330 BioCyc
Ensembl Genes ENSRNOG00000013628 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018349 ENTREZGENE
  ENSRNOT00000018349.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot
InterPro Peptidase_S1_Elastase_sf UniProtKB/Swiss-Prot
  Peptidase_S1_PA UniProtKB/Swiss-Prot
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot
  Peptidase_S1A UniProtKB/Swiss-Prot
  Trypsin_dom UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
KEGG Report rno:24332 UniProtKB/Swiss-Prot
NCBI Gene 24332 ENTREZGENE
PANTHER CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER UniProtKB/Swiss-Prot
  CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B UniProtKB/Swiss-Prot
Pfam Trypsin UniProtKB/Swiss-Prot
PhenoGen Cela2a PhenoGen
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot
PROSITE TRYPSIN_DOM UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013628 RatGTEx
SMART Tryp_SPc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot
UniProt A0ABK0LBE3_RAT UniProtKB/TrEMBL
  A6ITW9 ENTREZGENE, UniProtKB/TrEMBL
  CEL2A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 Cela2a  chymotrypsin like elastase 2A  Cela2a  chymotrypsin-like elastase family, member 2A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-05-18 Cela2a  chymotrypsin-like elastase family, member 2A  Ela2a  elastase 2A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Ela2a  elastase 2A  Ela2  elastase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Ela2  elastase 2    Elastase 2, pancreatic  Name updated 625702 APPROVED
2002-06-10 Ela2  Elastase 2, pancreatic      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference