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Gene: Polr1g (RNA polymerase I subunit G) Rattus norvegicus

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Symbol:

Polr1g

Name:

RNA polymerase I subunit G

RGD ID:

1591707

Description:

Predicted to be involved in transcription initiation at RNA polymerase I promoter. Predicted to act upstream of or within rRNA transcription. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in multiple myeloma. Orthologous to human POLR1G (RNA polymerase I subunit G); PARTICIPATES IN RNA polymerase I transcription pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CD3E antigen, epsilon polypeptide-associated protein; CD3e molecule associated protein; CD3e molecule, epsilon associated protein; Cd3eap; DNA-directed RNA polymerase I subunit RPA34; LOC292674; LOC680493; RGD1305916; similar to RIKEN cDNA 2610103M17; similar to RNA polymerase I-associated factor PAF49

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	POLR1G (RNA polymerase I subunit G)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Polr1g (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Polr1g (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	POLR1G (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	POLR1G (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Polr1g (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	POLR1G (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	POLR1G (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Polr1g (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Polr1g (RNA polymerase I subunit G)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	POLR1G (RNA polymerase I subunit G)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Polr1g (RNA polymerase I subunit G)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cd3eap (CD3e molecule, epsilon associated protein)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cd3eap (CD3e molecule, epsilon associated protein)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	88,135,493 - 88,138,769 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	88,135,493 - 88,138,769 (-)	Ensembl				GRCr8
mRatBN7.2	1	79,007,490 - 79,010,766 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	79,007,490 - 79,010,766 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	84,396,350 - 84,399,607 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	92,954,064 - 92,957,338 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	86,151,448 - 86,154,705 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	80,267,725 - 80,271,001 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	80,267,725 - 80,271,001 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	81,533,986 - 81,537,262 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	78,722,001 - 78,725,277 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	73,469,478 - 73,472,754 (-)	NCBI		Celera
RGSC_v3.1	1	78,800,727 - 78,829,737 (-)	NCBI
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

multiple myeloma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

4-aminobenzohydrazide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

benzene-1,2,4-triol (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chromium(6+) (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

coumarin (ISO)

DDE (ISO)

deoxynivalenol (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

dioxygen (EXP,ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenthion (ISO)

formaldehyde (ISO)

FR900359 (ISO)

gentamycin (EXP)

geraniol (ISO)

hydrogen peroxide (ISO)

leflunomide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methidathion (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorooctanoic acid (ISO)

quercetin (ISO)

senecionine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

rRNA transcription (IEA,ISO)

transcription by RNA polymerase I (IEA)

transcription elongation by RNA polymerase I (IEA,ISO)

transcription initiation at RNA polymerase I promoter (IEA,ISO)

Cellular Component

fibrillar center (IEA,ISO)

nucleolus (IEA,ISO)

nucleoplasm (IEA,ISO)

RNA polymerase I complex (IBA,IEA,ISO)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase I transcription pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Comprehensive gene review and curation	RGD comprehensive gene curation
4.	RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.	Schneider DA Gene. 2012 Feb 10;493(2):176-84. doi: 10.1016/j.gene.2011.08.006. Epub 2011 Aug 26.
5.	Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation.	Vangsted A, etal., Int J Cancer. 2007 Mar 1;120(5):1036-45. doi: 10.1002/ijc.22411.
6.	Conservation between the RNA polymerase I, II, and III transcription initiation machineries.	Vannini A and Cramer P, Mol Cell. 2012 Feb 24;45(4):439-46. doi: 10.1016/j.molcel.2012.01.023.

Additional References at PubMed

PMID:12477932	PMID:15226435	PMID:22658674

Genomics

Comparative Map Data

Polr1g
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	88,135,493 - 88,138,769 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	88,135,493 - 88,138,769 (-)	Ensembl				GRCr8
mRatBN7.2	1	79,007,490 - 79,010,766 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	79,007,490 - 79,010,766 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	84,396,350 - 84,399,607 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	92,954,064 - 92,957,338 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	86,151,448 - 86,154,705 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	80,267,725 - 80,271,001 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	80,267,725 - 80,271,001 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	81,533,986 - 81,537,262 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	78,722,001 - 78,725,277 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	73,469,478 - 73,472,754 (-)	NCBI		Celera
RGSC_v3.1	1	78,800,727 - 78,829,737 (-)	NCBI
Cytogenetic Map	1	q21	NCBI

POLR1G
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	45,406,644 - 45,410,737 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	45,406,644 - 45,410,737 (+)	Ensembl			hg38	GRCh38
GRCh37	19	45,909,902 - 45,913,995 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	50,601,307 - 50,605,864 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	42,715,573 - 42,720,130 (+)	NCBI		Celera
Cytogenetic Map	19	q13.32	NCBI
HuRef	19	42,339,795 - 42,344,365 (+)	NCBI		HuRef
CHM1_1	19	45,912,759 - 45,917,316 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	48,233,891 - 48,237,984 (+)	NCBI		T2T-CHM13v2.0

Polr1g
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	19,089,932 - 19,093,408 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	19,089,939 - 19,093,408 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	19,356,007 - 19,359,483 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	19,356,014 - 19,359,483 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	19,941,356 - 19,944,832 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	18,515,371 - 18,517,941 (-)	NCBI		MGSCv36	mm8
Celera	7	16,762,761 - 16,766,237 (-)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	9.62	NCBI

Polr1g
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955555	2,391,106 - 2,393,369 (+)	Ensembl
ChiLan1.0	NW_004955555	2,389,569 - 2,393,410 (+)	NCBI	ChiLan1.0	ChiLan1.0

POLR1G
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	51,567,306 - 51,570,495 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	53,438,850 - 53,442,041 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	42,354,919 - 42,359,537 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	50,950,958 - 50,954,115 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	50,951,038 - 50,953,826 (+)	Ensembl			panPan2	panpan1.1

POLR1G
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	110,146,495 - 110,149,338 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	110,146,012 - 110,149,186 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	109,631,024 - 109,633,707 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	110,679,369 - 110,682,052 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	110,679,660 - 110,682,579 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	110,354,996 - 110,357,679 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	109,989,155 - 109,991,838 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	110,858,466 - 110,861,149 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Polr1g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	17,505,339 - 17,507,751 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936706	1,852,359 - 1,857,623 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936706	1,852,350 - 1,854,921 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLR1G
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	51,781,347 - 51,785,104 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	51,780,709 - 51,783,696 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

POLR1G
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	38,853,681 - 38,857,241 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	38,853,874 - 38,859,288 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	18,457,653 - 18,461,250 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Polr1g
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624907	2,286,050 - 2,288,242 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624907	2,286,040 - 2,288,533 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Polr1g
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	171,261,511 - 171,264,821 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Polr1g
17 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	103
Count of miRNA genes:	78
Interacting mature miRNAs:	91
Transcripts:	ENSRNOT00000034266
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat

Markers in Region

BE120839

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	79,008,387 - 79,008,538 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	80,268,623 - 80,268,773	NCBI	Rnor6.0
Rnor_5.0	1	81,534,884 - 81,535,034	UniSTS	Rnor5.0
RGSC_v3.4	1	78,722,899 - 78,723,049	UniSTS	RGSC3.4
Celera	1	73,470,376 - 73,470,526	UniSTS
RH 3.4 Map	1	794.6	UniSTS
Cytogenetic Map	1	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC158735	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000034266 ⟹ ENSRNOP00000029706

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	88,135,493 - 88,138,769 (-)	Ensembl
mRatBN7.2 Ensembl	1	79,007,490 - 79,010,766 (-)	Ensembl
Rnor_6.0 Ensembl	1	80,267,725 - 80,271,001 (-)	Ensembl

RefSeq Acc Id:

NM_001109416 ⟹ NP_001102886

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	88,135,493 - 88,138,769 (-)	NCBI
mRatBN7.2	1	79,007,490 - 79,010,766 (-)	NCBI
Rnor_6.0	1	80,267,725 - 80,271,001 (-)	NCBI
Rnor_5.0	1	81,533,986 - 81,537,262 (-)	NCBI
RGSC_v3.4	1	78,722,001 - 78,725,277 (-)	RGD
Celera	1	73,469,478 - 73,472,754 (-)	RGD

Sequence:

show sequence

TGGGCAGCGTTCCGCGCAGGTCCTGCGTGGACTTCTCTAGAGTTGGGATGGAGGGTACCTCGGC
CTGTGGTGCCACTCGGTTCTCCTGCCCACCCCACTTCACGGCGATGTCTCCAGACTCGGATCCC
CCCCGTTTCTCCTTGGAGGCGCTTACAGGTCCAGATACGGAAGTGTGGCTTATCCGAGCCCCTG
CAGACTTCGCCCCACAATGCCTCAATGGGCGGCGTGTGCCTCTCTCTGGCTCCAAGACTGTTAA
GGGCAAACTGGACGGCAAGAAGCACCGATACCGGGTCGTTACCAGCGGCCCCCAGGCTGGGGAA
GCCACCTTGCTCATGTCTTCAATGGAGGCAGGTGGCAGGCTCGCCTGTGCCCCTGCCCCCAACG
GAAGCTTAAGGATCATGGAGGGTCCTCAGGAATATCTTATCTCTCGGGTCCCCCTGCAGCCGAT
CCCCACAAGCCTGCCACCTCAGATCCCTGCTGGCCTGCGGCCTCGCTTCTCTGCCTTCGGAGGT
AGCCCTCCTGTCACAGGGCCGGGTTCAGCCTCGGTTCTGAGGTCCCCCACTTCAGGGAAGAGGA
AAAAGAAGAGAAAGGATGCAGAGGCCTCAGACACTCAGGAGGCTGTGAACAGGCACGAGGCCAT
GAAAGTGGAAACAGCCTGGGGTGACCTAGGAATGGATGTGAAGAAGAAGAGAAAGAGGCATCAT
GTGGATGAGGAGGCAGAGGCTAAGGGGATGGAGCCGCTGGCCGAGCTGGCCGAGCTGCCAGTCC
CCTCTGCCACCGGCAGCAAGAAGAGGAAGAAGTCCAAGGGGGCAGAGACACTCCAGGCGGAAGA
GGATCCGGGGCACATGGAACCCGTGGCTCAGACAGAGCCTCCTGAGGGGCCCTTCCTGTCTCCC
ACCAAAAAGAGAAAGAGGCAGAAGCAAGCTGAAGGGGCAGAGGAAGTGGATGGCACCATGGCTG
ACTCTCAGCCACAGGTCACTGTGGAACCCCACGAGGAAACCATACTACTGTCCCCCACAAAGAA
GAGGAAAAAAGAAAAGAGACAGAATTTGGTGATGGAGGCAGAGATGGGCCTCCCTGGAGTGCTC
ATGGAGACGGAGCTTTTAGAACCAGGGCTTCAGGCTGAAGTAGCTCCTGTGTCCCCCAAGAAAA
CAAAGAAGAAGAAAAAGGGGAAGTGTGTGGATGAGGCACTGGCCTTGGCAGCAGAGGTGACAGA
GGCTGCACTTCCAGCTGATTTTGAGCCCCAGGGGGCTCCAGTACCCAGCAAGAAAAAAGAGAGA
GGACAGAAAGCAACAGAGCCTGGGTCTGAGGTGACTGACCCAAGACAATCTGAGGAACCAGAGC
CCAGGGCAGGTCAGGGATCCCCCAAGAAGAAGAAAAAGAAGGATCAGGAAAGTAGGGTACAAAA
CACCATTCCCCACTGAGAGATGTCTCCCACGGGACAGGAGGAGCCATCACACCACCCTGAGGAA
GGGGAAAGGGAGGAACTTGCAGGGTTATGGTCAGACATCAGCGGTGTAGCCGCTCCCTGCTCCC
TCCCCAAGCAAACATGCACAACCACAAGAGCCTGGGCATGGAAATGCTTTATTGTGTGACACGG
AGCCTCGGTGGCAGGGGGTCATCGGGGCACTTTGAGGAAGGGTTCATGTAGTACTTCAAAAAGC
CTGCGGGCCTGAAGACAAGGGGAGAGGAGAACTTGTCATTAAAGATACTGTTTGCCTGTTCTGT
TTGGTGCGGGGTTCCGCCTCTTATTCTCCTGTCGAGGAGCTTTGGGTGTGTGGTTTCTACTTGA
GGCTGGCCAGAGGTGGGTGTAAATGGACCTAAAACTAGTCCATCGGCTGGGCATTGCTGCTGCA
CACCTTTAATCCCAGCGCTTGGGAGGCTGAGGCAGGAGGATCAGAAGTGTAACCTCCGGTTGGG
GATTTAGCTCAGTGGTAGAGCGCTTGCCTAGCAAGCGCAAGGCCCTGGGTTCGGTCCCCAGCTC
CGAAAAAAAGAAAAAAGAAAAAAAAAAAAAAAAAAAAAGAAGTGTAACCTCAGCTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102886	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM08209	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000029706
	ENSRNOP00000029706.4

RefSeq Acc Id:

NP_001102886 ⟸ NM_001109416

- UniProtKB:

D4ADE7 (UniProtKB/TrEMBL), A6J8M5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEGTSACGATRFSCPPHFTAMSPDSDPPRFSLEALTGPDTEVWLIRAPADFAPQCLNGRRVPLS
GSKTVKGKLDGKKHRYRVVTSGPQAGEATLLMSSMEAGGRLACAPAPNGSLRIMEGPQEYLISR
VPLQPIPTSLPPQIPAGLRPRFSAFGGSPPVTGPGSASVLRSPTSGKRKKKRKDAEASDTQEAV
NRHEAMKVETAWGDLGMDVKKKRKRHHVDEEAEAKGMEPLAELAELPVPSATGSKKRKKSKGAE
TLQAEEDPGHMEPVAQTEPPEGPFLSPTKKRKRQKQAEGAEEVDGTMADSQPQVTVEPHEETIL
LSPTKKRKKEKRQNLVMEAEMGLPGVLMETELLEPGLQAEVAPVSPKKTKKKKKGKCVDEALAL
AAEVTEAALPADFEPQGAPVPSKKKERGQKATEPGSEVTDPRQSEEPEPRAGQGSPKKKKKKDQ
ESRVQNTIPH

hide sequence

Ensembl Acc Id:

ENSRNOP00000029706 ⟸ ENSRNOT00000034266

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ADE7-F1-model_v2	AlphaFold	D4ADE7	1-458	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689769

Promoter ID:

EPDNEW_R293

Type:

initiation region

Name:

Cd3eap_1

Description:

CD3e molecule associated protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	80,270,984 - 80,271,044	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1591707	AgrOrtholog
BioCyc Gene	G2FUF-60510	BioCyc
Ensembl Genes	ENSRNOG00000016825	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034266	ENTREZGENE
	ENSRNOT00000034266.6	UniProtKB/TrEMBL
Gene3D-CATH	6.20.250.70	UniProtKB/TrEMBL
InterPro	RNA_pol1_su_RPA34	UniProtKB/TrEMBL
KEGG Report	rno:680493	UniProtKB/TrEMBL
NCBI Gene	680493	ENTREZGENE
PANTHER	DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34	UniProtKB/TrEMBL
	PTHR15484	UniProtKB/TrEMBL
Pfam	RNA_polI_A34	UniProtKB/TrEMBL
PhenoGen	Polr1g	PhenoGen
RatGTEx	ENSRNOG00000016825	RatGTEx
UniProt	A6J8M5	ENTREZGENE, UniProtKB/TrEMBL
	D4ADE7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-04-30	Polr1g	RNA polymerase I subunit G	Cd3eap	CD3e molecule associated protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-01-13	Cd3eap	CD3e molecule associated protein	Cd3eap	CD3e molecule, epsilon associated protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-02-04	Cd3eap	CD3e molecule, epsilon associated protein	Cd3eap	CD3E antigen, epsilon polypeptide-associated protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-06-15	Cd3eap	CD3E antigen, epsilon polypeptide-associated protein	RGD1305916	similar to RIKEN cDNA 2610103M17	Data merged from RGD:1305916	737654	PROVISIONAL
2008-07-08	Cd3eap	CD3E antigen, epsilon polypeptide-associated protein	LOC686776	similar to RNA polymerase I-associated factor PAF49	Data merged from RGD:1593686	1643240	APPROVED
2008-04-30	RGD1305916	similar to RIKEN cDNA 2610103M17	RGD1305916_predicted	similar to RIKEN cDNA 2610103M17 (predicted)	'predicted' is removed	2292626	APPROVED
2008-03-05	Cd3eap	CD3E antigen, epsilon polypeptide-associated protein	LOC680493	similar to RNA polymerase I-associated factor PAF49	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC680493	similar to RNA polymerase I-associated factor PAF49			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC686776	similar to RNA polymerase I-associated factor PAF49			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-20	RGD1305916_predicted	similar to RIKEN cDNA 2610103M17 (predicted)	LOC292674_predicted		Symbol and Name status set to approved	1331353	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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