Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mettl27 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of METTL27 mRNA | CTD | PMID:36331819 | Mettl27 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of METTL27 mRNA | CTD | PMID:22206623 | Mettl27 | Rat | 17beta-estradiol | increases expression | ISO | Mettl27 (Mus musculus) | 6480464 | Estradiol results in increased expression of METTL27 mRNA | CTD | PMID:39298647 | Mettl27 | Rat | 17beta-estradiol | decreases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of METTL27 mRNA | CTD | PMID:31614463 | Mettl27 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of METTL27 mRNA; [TIPARP gene more ... | CTD | PMID:16214954|PMID:25975270 | Mettl27 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of METTL27 mRNA | CTD | PMID:33387578 | Mettl27 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of METTL27 mRNA | CTD | PMID:34747641 | Mettl27 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mettl27 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of METTL27 mRNA | CTD | PMID:21570461 | Mettl27 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mettl27 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of METTL27 mRNA | CTD | PMID:19933214 | Mettl27 | Rat | 2-butoxyethanol | increases expression | ISO | Mettl27 (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of METTL27 mRNA | CTD | PMID:19812364 | Mettl27 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Mettl27 (Mus musculus) | 6480464 | bisphenol S results in increased expression of METTL27 mRNA | CTD | PMID:39298647 | Mettl27 | Rat | aflatoxin B1 | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of METTL27 mRNA | CTD | PMID:21641981 | Mettl27 | Rat | arsenite(3-) | multiple interactions | ISO | METTL27 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to METTL27 mRNA] | CTD | PMID:32406909 | Mettl27 | Rat | arsenous acid | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of METTL27 mRNA | CTD | PMID:20458559 | Mettl27 | Rat | benzo[a]pyrene | increases expression | ISO | Mettl27 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of METTL27 mRNA | CTD | PMID:19770486 | Mettl27 | Rat | benzo[a]pyrene | decreases methylation | ISO | METTL27 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of WBSCR27 promoter | CTD | PMID:27901495 | Mettl27 | Rat | benzo[a]pyrene | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of METTL27 mRNA] | CTD | PMID:22228805 | Mettl27 | Rat | benzo[a]pyrene | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of METTL27 mRNA | CTD | PMID:21871943 | Mettl27 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of WBSCR27 mRNA | CTD | PMID:31163220 | Mettl27 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of METTL27 mRNA | CTD | PMID:25181051 | Mettl27 | Rat | bisphenol A | decreases expression | ISO | Mettl27 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of METTL27 mRNA | CTD | PMID:33221593 | Mettl27 | Rat | bisphenol A | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of METTL27 mRNA | CTD | PMID:29275510 | Mettl27 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of METTL27 mRNA | CTD | PMID:30816183|PMID:32528016 | Mettl27 | Rat | bortezomib | decreases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Bortezomib results in decreased expression of METTL27 mRNA | CTD | PMID:20977926 | Mettl27 | Rat | carbon nanotube | decreases expression | ISO | Mettl27 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of METTL27 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681|PMID:25620056 | Mettl27 | Rat | choline | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Mettl27 | Rat | cisplatin | multiple interactions | ISO | METTL27 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of METTL27 mRNA | CTD | PMID:27392435 | Mettl27 | Rat | cisplatin | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of METTL27 mRNA | CTD | PMID:27392435 | Mettl27 | Rat | diarsenic trioxide | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of METTL27 mRNA | CTD | PMID:20458559 | Mettl27 | Rat | epoxiconazole | decreases expression | ISO | Mettl27 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of METTL27 mRNA | CTD | PMID:35436446 | Mettl27 | Rat | ethanol | affects expression | ISO | Mettl27 (Mus musculus) | 6480464 | Ethanol affects the expression of METTL27 mRNA | CTD | PMID:30319688 | Mettl27 | Rat | ethylparaben | decreases expression | ISO | METTL27 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of METTL27 mRNA | CTD | PMID:37690743 | Mettl27 | Rat | folic acid | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of METTL27 mRNA; [Methionine deficiency co-treated more ... | CTD | PMID:20938992|PMID:22206623 | Mettl27 | Rat | fonofos | increases methylation | ISO | METTL27 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of METTL27 promoter | CTD | PMID:22847954 | Mettl27 | Rat | iron dichloride | decreases expression | ISO | METTL27 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of METTL27 mRNA | CTD | PMID:35984750 | Mettl27 | Rat | L-methionine | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Mettl27 | Rat | okadaic acid | decreases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of METTL27 mRNA | CTD | PMID:38832940 | Mettl27 | Rat | paracetamol | affects expression | ISO | Mettl27 (Mus musculus) | 6480464 | Acetaminophen affects the expression of METTL27 mRNA | CTD | PMID:17562736 | Mettl27 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of METTL27 mRNA | CTD | PMID:33387578 | Mettl27 | Rat | paracetamol | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of METTL27 mRNA | CTD | PMID:22230336 | Mettl27 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of WBSCR27 mRNA | CTD | PMID:32680482 | Mettl27 | Rat | parathion | increases methylation | ISO | METTL27 (Homo sapiens) | 6480464 | Parathion results in increased methylation of METTL27 promoter | CTD | PMID:22847954 | Mettl27 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of METTL27 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Mettl27 | Rat | phenobarbital | multiple interactions | ISO | Mettl27 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of METTL27 mRNA] | CTD | PMID:19482888 | Mettl27 | Rat | phenobarbital | increases expression | ISO | Mettl27 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of METTL27 mRNA | CTD | PMID:19482888 | Mettl27 | Rat | pirinixic acid | multiple interactions | ISO | METTL27 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Mettl27 | Rat | pirinixic acid | increases expression | ISO | Mettl27 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of METTL27 mRNA | CTD | PMID:18301758|PMID:23811191 | Mettl27 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Mettl27 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of METTL27 mRNA | CTD | PMID:28903501 | Mettl27 | Rat | resveratrol | multiple interactions | ISO | METTL27 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of METTL27 mRNA | CTD | PMID:23557933 | Mettl27 | Rat | rotenone | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Rotenone results in increased expression of METTL27 mRNA | CTD | PMID:29955902 | Mettl27 | Rat | temozolomide | increases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of METTL27 mRNA | CTD | PMID:31758290 | Mettl27 | Rat | terbufos | increases methylation | ISO | METTL27 (Homo sapiens) | 6480464 | terbufos results in increased methylation of METTL27 promoter | CTD | PMID:22847954 | Mettl27 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of METTL27 mRNA | CTD | PMID:34492290 | Mettl27 | Rat | titanium dioxide | decreases methylation | ISO | Mettl27 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of WBSCR27 gene | CTD | PMID:35295148 | Mettl27 | Rat | urethane | decreases expression | ISO | METTL27 (Homo sapiens) | 6480464 | Urethane results in decreased expression of METTL27 mRNA | CTD | PMID:28818685 | Mettl27 | Rat | valproic acid | affects expression | ISO | Mettl27 (Mus musculus) | 6480464 | Valproic Acid affects the expression of METTL27 mRNA | CTD | PMID:17292431 | Mettl27 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of METTL27 mRNA | CTD | PMID:23034163 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















