Gene: Lekr1 (leucine, glutamate and lysine rich 1) Rattus norvegicus
Analyze
Symbol:
Lekr1
Name:
leucine, glutamate and lysine rich 1
RGD ID:
1565425
Description:
Orthologous to human LEKR1 (leucine, glutamate and lysine rich 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
hypothetical protein LOC691104; leucine-, glutamate- and lysine-rich protein 1; LOC361953; LOC691104; RGD1562738; RGD1565425; similar to Restin
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
LEKR1 (leucine, glutamate and lysine rich 1) HGNC
HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Lekr1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Lekr1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
LEKR1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
LEKR1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Lekr1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
LEKR1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
LEKR1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Lekr1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Lekr1 (leucine, glutamate and lysine rich 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
GDF10 (growth differentiation factor 10) HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
LEKR1 (leucine, glutamate and lysine rich 1)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
LEKR1 (leucine, glutamate and lysine rich 1)
Alliance
DIOPT (HGNC|OrthoInspector|PhylomeDB)
Mus musculus (house mouse):
Lekr1 (leucine, glutamate and lysine rich 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
zmp:0000001018
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
zmp:0000001018
Alliance
DIOPT (OrthoFinder|OrthoInspector|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
lekr1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 152,195,003 - 152,376,389 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 2 152,201,182 - 152,370,542 (+) Ensembl GRCr8 mRatBN7.2 2 149,889,615 - 150,061,167 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 149,891,106 - 150,060,469 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 2 156,993,726 - 157,168,707 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 155,044,220 - 155,219,213 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 149,676,915 - 149,851,916 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 157,451,912 - 157,621,908 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 157,453,428 - 157,620,210 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 2 176,820,259 - 176,989,613 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 2 155,462,085 - 155,632,219 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 2 144,303,340 - 144,474,116 (+) NCBI Celera Cytogenetic Map 2 q31 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Lekr1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Lekr1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of LEKR1 mRNA CTD PMID:20159946|PMID:21889950 Lekr1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of LEKR1 mRNA CTD PMID:33387578 Lekr1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Lekr1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of LEKR1 mRNA CTD PMID:26377647 Lekr1 Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of LEKR1 mRNA CTD PMID:32109520 Lekr1 Rat 2-palmitoylglycerol increases expression ISO LEKR1 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of LEKR1 mRNA CTD PMID:37199045 Lekr1 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of LEKR1 mRNA CTD PMID:31881176 Lekr1 Rat acrylamide affects expression EXP 6480464 Acrylamide affects the expression of LEKR1 mRNA CTD PMID:28959563 Lekr1 Rat aflatoxin B1 decreases methylation ISO LEKR1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of LEKR1 gene CTD PMID:27153756 Lekr1 Rat all-trans-retinoic acid decreases expression ISO LEKR1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of LEKR1 mRNA CTD PMID:33167477 Lekr1 Rat antirheumatic drug increases expression ISO LEKR1 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of LEKR1 mRNA CTD PMID:24449571 Lekr1 Rat aristolochic acid A increases expression ISO LEKR1 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of LEKR1 mRNA CTD PMID:33212167 Lekr1 Rat benzo[a]pyrene increases methylation ISO LEKR1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of LEKR1 5' UTR; Benzo(a)pyrene results in increased methylation of more ... CTD PMID:27901495 Lekr1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of LEKR1 mRNA CTD PMID:25181051 Lekr1 Rat bisphenol A increases methylation ISO LEKR1 (Homo sapiens) 6480464 bisphenol A results in increased methylation of LEKR1 gene CTD PMID:31601247 Lekr1 Rat Butylbenzyl phthalate increases methylation ISO Lekr1 (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of LEKR1 intron CTD PMID:28392331 Lekr1 Rat DDE decreases expression ISO LEKR1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of LEKR1 mRNA CTD PMID:38568856 Lekr1 Rat furan increases expression EXP 6480464 furan results in increased expression of LEKR1 mRNA CTD PMID:25539665 Lekr1 Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of LEKR1 mRNA CTD PMID:33387578 Lekr1 Rat okadaic acid decreases expression ISO LEKR1 (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of LEKR1 mRNA CTD PMID:38832940 Lekr1 Rat orphenadrine affects expression EXP 6480464 Orphenadrine affects the expression of LEKR1 mRNA CTD PMID:23665939 Lekr1 Rat permethrin decreases expression ISO LEKR1 (Homo sapiens) 6480464 Permethrin results in decreased expression of LEKR1 mRNA CTD PMID:37047231 Lekr1 Rat propanal increases expression ISO LEKR1 (Homo sapiens) 6480464 propionaldehyde results in increased expression of LEKR1 mRNA CTD PMID:26079696 Lekr1 Rat sodium fluoride decreases expression ISO Lekr1 (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of LEKR1 mRNA CTD PMID:27862939 Lekr1 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of LEKR1 mRNA CTD PMID:34492290 Lekr1 Rat titanium dioxide decreases methylation ISO Lekr1 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of LEKR1 gene; titanium dioxide results in decreased methylation more ... CTD PMID:35295148 Lekr1 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of LEKR1 mRNA CTD PMID:33387578 Lekr1 Rat trovafloxacin increases expression ISO Lekr1 (Mus musculus) 6480464 trovafloxacin results in increased expression of LEKR1 mRNA CTD PMID:35537566 Lekr1 Rat valproic acid decreases methylation ISO LEKR1 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of LEKR1 gene CTD PMID:29154799 Lekr1 Rat valproic acid increases expression ISO LEKR1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of LEKR1 mRNA CTD PMID:28001369
References
Additional References at PubMed
Genomics
Comparative Map Data
Lekr1 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 2 152,195,003 - 152,376,389 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 2 152,201,182 - 152,370,542 (+) Ensembl GRCr8 mRatBN7.2 2 149,889,615 - 150,061,167 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 2 149,891,106 - 150,060,469 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 2 156,993,726 - 157,168,707 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 2 155,044,220 - 155,219,213 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 2 149,676,915 - 149,851,916 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 2 157,451,912 - 157,621,908 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 2 157,453,428 - 157,620,210 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 2 176,820,259 - 176,989,613 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 2 155,462,085 - 155,632,219 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 2 144,303,340 - 144,474,116 (+) NCBI Celera Cytogenetic Map 2 q31 NCBI
LEKR1 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 3 156,826,353 - 157,046,129 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 3 156,825,481 - 157,046,129 (+) Ensembl hg38 GRCh38 GRCh37 3 156,544,142 - 156,763,918 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 3 158,026,790 - 158,246,612 (+) NCBI Build 36 Build 36 hg18 NCBI36 Celera 3 154,967,679 - 155,187,419 (+) NCBI Celera Cytogenetic Map 3 q25.31 NCBI HuRef 3 153,940,639 - 154,160,281 (+) NCBI HuRef CHM1_1 3 156,507,104 - 156,726,943 (+) NCBI CHM1_1 T2T-CHM13v2.0 3 159,601,066 - 159,820,688 (+) NCBI T2T-CHM13v2.0
Lekr1 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 3 65,566,960 - 65,743,948 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 3 65,573,649 - 65,738,776 (+) Ensembl GRCm39 Ensembl GRCm39 GRCm38 3 65,659,539 - 65,836,527 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 3 65,666,228 - 65,831,355 (+) Ensembl mm10 GRCm38 MGSCv37 3 65,870,709 - 65,919,088 (+) NCBI MGSCv37 MGSCv37 mm9 NCBIm37 MGSCv36 3 65,754,197 - 65,774,108 (+) NCBI MGSCv36 mm8 Celera 3 65,921,077 - 65,969,458 (+) NCBI Celera Cytogenetic Map 3 E1 NCBI cM Map 3 30.24 NCBI
Lekr1 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 NW_004955448 7,834,824 - 8,030,085 (+) NCBI ChiLan1.0 ChiLan1.0
LEKR1 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 2 154,740,632 - 154,959,948 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 3 154,742,296 - 154,962,526 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 3 153,881,467 - 154,095,829 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 3 161,935,058 - 162,149,152 (+) NCBI PanPan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 3 161,935,058 - 162,149,152 (+) Ensembl panPan2 panpan1.1
LEKR1 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 23 50,389,960 - 50,561,281 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 23 50,370,297 - 50,558,916 (+) Ensembl canFam3 CanFam3.1 Dog10K_Boxer_Tasha 23 50,263,523 - 50,434,235 (+) NCBI Dog10K_Boxer_Tasha Dog10K_Boxer_Tasha ROS_Cfam_1.0 23 51,023,131 - 51,194,527 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 23 51,003,114 - 51,192,140 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 23 50,607,155 - 50,778,135 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 23 50,658,190 - 50,830,259 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 23 50,944,819 - 51,114,766 (+) NCBI UU_Cfam_GSD_1.0 UU_Cfam_GSD_1.0
Lekr1 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405602 85,761,031 - 85,923,313 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936519 3,825,371 - 3,971,925 (+) Ensembl SpeTri2.0 Ensembl SpeTri2.0 NW_004936519 3,810,766 - 3,972,956 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
LEKR1 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 13 96,652,441 - 96,879,731 (+) Ensembl susScr11 Sscrofa11.1 Sscrofa11.1 13 96,641,062 - 96,882,709 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 13 104,757,949 - 104,997,283 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
LEKR1
Lekr1
Lekr1
miRNA Target Status (No longer updated)
Predicted Target Of
Count of predictions: 39 Count of miRNA genes: 38 Interacting mature miRNAs: 39 Transcripts: ENSRNOT00000051494 Prediction methods: Miranda, Rnahybrid Result types: miRGate_prediction 
