Smim29 (small integral membrane protein 29) - Rat Genome Database

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Gene: Smim29 (small integral membrane protein 29) Rattus norvegicus
Analyze
Symbol: Smim29
Name: small integral membrane protein 29
RGD ID: 1564450
Description: Orthologous to human SMIM29 (small integral membrane protein 29); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical LOC294291; hypothetical protein LOC294291; LOC294291; RGD1564450; RGD1564450; uncharacterized protein C6orf1 homolog; uncharacterized protein LOC294291
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8205,620,686 - 5,622,730 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl205,620,686 - 5,623,037 (-)EnsemblGRCr8
mRatBN7.2205,618,845 - 5,620,856 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl205,618,845 - 5,620,813 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx206,331,332 - 6,333,345 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0205,693,084 - 5,695,097 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0206,173,220 - 6,175,233 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0207,140,241 - 7,142,316 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl207,140,245 - 7,142,213 (-)Ensemblrn6Rnor6.0
Rnor_5.0209,342,411 - 9,344,670 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4205,773,534 - 5,775,502 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera207,181,798 - 7,183,766 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Smim29
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8205,620,686 - 5,622,730 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl205,620,686 - 5,623,037 (-)EnsemblGRCr8
mRatBN7.2205,618,845 - 5,620,856 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl205,618,845 - 5,620,813 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx206,331,332 - 6,333,345 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0205,693,084 - 5,695,097 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0206,173,220 - 6,175,233 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0207,140,241 - 7,142,316 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl207,140,245 - 7,142,213 (-)Ensemblrn6Rnor6.0
Rnor_5.0209,342,411 - 9,344,670 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4205,773,534 - 5,775,502 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera207,181,798 - 7,183,766 (-)NCBICelera
Cytogenetic Map20p12NCBI
SMIM29
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38634,246,395 - 34,249,006 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl634,246,381 - 34,249,108 (-)Ensemblhg38GRCh38
GRCh37634,214,172 - 34,216,783 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36634,322,135 - 34,324,882 (-)NCBIBuild 36Build 36hg18NCBI36
Celera635,768,530 - 35,771,279 (-)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef633,936,822 - 33,939,571 (-)NCBIHuRef
CHM1_1634,216,746 - 34,219,495 (-)NCBICHM1_1
T2T-CHM13v2.0634,070,100 - 34,072,713 (-)NCBIT2T-CHM13v2.0
Smim29
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391727,782,743 - 27,784,706 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1727,782,547 - 27,784,730 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381727,563,769 - 27,565,728 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,563,573 - 27,565,756 (-)Ensemblmm10GRCm38
MGSCv371727,700,714 - 27,702,672 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361727,291,358 - 27,293,289 (-)NCBIMGSCv36mm8
Celera1728,115,873 - 28,117,831 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.53NCBI
Smim29
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554372,486,918 - 2,489,003 (-)Ensembl
ChiLan1.0NW_0049554372,486,918 - 2,489,003 (-)NCBIChiLan1.0ChiLan1.0
SMIM29
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2548,722,458 - 48,725,172 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1644,589,731 - 44,592,457 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0633,816,762 - 33,819,465 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1634,920,643 - 34,923,316 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl634,920,643 - 34,923,311 (-)EnsemblpanPan2panpan1.1
SMIM29
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1123,538,756 - 3,541,344 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha123,554,313 - 3,556,924 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0123,874,885 - 3,877,494 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl123,874,890 - 3,877,928 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1123,537,240 - 3,539,849 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0123,618,753 - 3,621,225 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0123,717,099 - 3,719,708 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Smim29
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494639,164,551 - 39,165,847 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647624,793,223 - 24,795,661 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647624,793,213 - 24,795,679 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100156657
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl730,329,550 - 30,332,126 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1730,329,547 - 30,332,166 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2734,990,226 - 34,992,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMIM29
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11737,845,160 - 37,847,944 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1737,846,855 - 37,847,851 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604434,161,143 - 34,163,841 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smim29
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1186,284,527 - 6,286,689 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Smim29
16 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2016693431Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362632310078622Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2016693431Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036263239244918Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
RH128050  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2205,618,454 - 5,618,649 (+)MAPPERmRatBN7.2
mRatBN7.2X31,610,924 - 31,611,116 (+)MAPPERmRatBN7.2
Rnor_6.0207,139,855 - 7,140,049NCBIRnor6.0
Rnor_6.0X33,348,165 - 33,348,356NCBIRnor6.0
Rnor_5.0209,342,210 - 9,342,404UniSTSRnor5.0
Rnor_5.0X33,695,628 - 33,695,819UniSTSRnor5.0
RGSC_v3.4X52,351,648 - 52,351,839UniSTSRGSC3.4
RGSC_v3.4205,773,144 - 5,773,338UniSTSRGSC3.4
Celera207,181,408 - 7,181,602UniSTS
CeleraX31,924,692 - 31,924,883UniSTS
RH 3.4 Map2076.95UniSTS
Cytogenetic Map20p12UniSTS
RH130079  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2205,618,876 - 5,619,070 (+)MAPPERmRatBN7.2
Rnor_6.0207,140,277 - 7,140,470NCBIRnor6.0
Rnor_5.0209,342,632 - 9,342,825UniSTSRnor5.0
RGSC_v3.4205,773,566 - 5,773,759UniSTSRGSC3.4
Celera207,181,830 - 7,182,023UniSTS
RH 3.4 Map2075.03UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000078918   ⟹   ENSRNOP00000072018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl205,620,686 - 5,623,037 (-)Ensembl
mRatBN7.2 Ensembl205,618,845 - 5,620,813 (-)Ensembl
Rnor_6.0 Ensembl207,140,245 - 7,142,213 (-)Ensembl
RefSeq Acc Id: NM_001106377   ⟹   NP_001099847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,620,686 - 5,622,654 (-)NCBI
mRatBN7.2205,618,845 - 5,620,813 (-)NCBI
Rnor_6.0207,140,245 - 7,142,213 (-)NCBI
Rnor_5.0209,342,411 - 9,344,670 (-)NCBI
RGSC_v3.4205,773,534 - 5,775,502 (-)RGD
Celera207,181,798 - 7,183,766 (-)RGD
Sequence:
RefSeq Acc Id: NM_001395665   ⟹   NP_001382594
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,620,686 - 5,622,696 (-)NCBI
mRatBN7.2205,618,845 - 5,620,855 (-)NCBI
RefSeq Acc Id: NM_001395666   ⟹   NP_001382595
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,620,686 - 5,622,696 (-)NCBI
mRatBN7.2205,618,845 - 5,620,855 (-)NCBI
RefSeq Acc Id: XM_017601591   ⟹   XP_017457080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,620,686 - 5,622,697 (-)NCBI
mRatBN7.2205,618,845 - 5,620,856 (-)NCBI
Rnor_6.0207,140,241 - 7,142,213 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063279028   ⟹   XP_063135098
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,620,686 - 5,622,655 (-)NCBI
RefSeq Acc Id: XM_063279029   ⟹   XP_063135099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8205,620,686 - 5,622,730 (-)NCBI
RefSeq Acc Id: NP_001099847   ⟸   NM_001106377
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: XP_017457080   ⟸   XM_017601591
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000072018   ⟸   ENSRNOT00000078918
RefSeq Acc Id: NP_001382595   ⟸   NM_001395666
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001382594   ⟸   NM_001395665
- Peptide Label: isoform 2
RefSeq Acc Id: XP_063135099   ⟸   XM_063279029
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063135098   ⟸   XM_063279028
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K1X2 (UniProtKB/TrEMBL),   A6JJM6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K1X2-F1-model_v2 AlphaFold A0A0G2K1X2 1-114 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701448
Promoter ID:EPDNEW_R11971
Type:multiple initiation site
Name:Smim29_1
Description:small integral membrane protein 29
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0207,142,261 - 7,142,321EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564450 AgrOrtholog
BioCyc Gene G2FUF-4465 BioCyc
Ensembl Genes ENSRNOG00000054374 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078918.3 UniProtKB/TrEMBL
InterPro DUF5546 UniProtKB/TrEMBL
  SMIM29 UniProtKB/TrEMBL
KEGG Report rno:294291 UniProtKB/TrEMBL
NCBI Gene 294291 ENTREZGENE
PANTHER PTHR47730 UniProtKB/TrEMBL
  SMALL INTEGRAL MEMBRANE PROTEIN 29 UniProtKB/TrEMBL
Pfam DUF5546 UniProtKB/TrEMBL
PhenoGen Smim29 PhenoGen
RatGTEx ENSRNOG00000054374 RatGTEx
UniProt A0A0G2K1X2 ENTREZGENE, UniProtKB/TrEMBL
  A6JJM5_RAT UniProtKB/TrEMBL
  A6JJM6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-20 Smim29  small integral membrane protein 29  RGD1564450  RGD1564450  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1564450  RGD1564450   RGD1564450_predicted  RGD1564450 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564450_predicted  RGD1564450 (predicted)  LOC294291  hypothetical LOC294291  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC294291  hypothetical LOC294291      Symbol and Name status set to provisional 70820 PROVISIONAL