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Gene: Rmdn1 (regulator of microtubule dynamics 1) Rattus norvegicus

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Symbol:

Rmdn1

Name:

regulator of microtubule dynamics 1

RGD ID:

1563085

Description:

Predicted to enable microtubule binding activity. Predicted to be located in microtubule and spindle pole. Predicted to be active in mitochondrion; mitotic spindle pole; and spindle microtubule. Orthologous to human RMDN1 (regulator of microtubule dynamics 1); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Fam82b; family with sequence similarity 82, member B; LOC500419; MGC112702; regulator of microtubule dynamics protein 1; RMD-1; similar to RIKEN cDNA 2410005O16

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RMDN1 (regulator of microtubule dynamics 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rmdn1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rmdn1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RMDN1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RMDN1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rmdn1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RMDN1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RMDN1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rmdn1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rmdn1 (regulator of microtubule dynamics 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MCTP2 (multiple C2 and transmembrane domain containing 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RMDN1 (regulator of microtubule dynamics 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rmdn1 (regulator of microtubule dynamics 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rmdn1 (regulator of microtubule dynamics 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F33H2.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F33H2.6	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rmdn1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	rmdn1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	37,867,172 - 37,890,826 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	37,867,263 - 38,007,420 (+)	Ensembl				GRCr8
mRatBN7.2	5	33,070,267 - 33,093,922 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	33,070,265 - 33,127,328 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	35,186,377 - 35,209,883 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	36,778,935 - 36,802,441 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	36,718,075 - 36,741,587 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	33,580,891 - 33,604,564 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	33,580,944 - 33,638,165 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	38,235,214 - 38,258,968 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	34,210,399 - 34,233,936 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	32,160,469 - 32,183,998 (+)	NCBI		Celera
Cytogenetic Map	5	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

aconitine (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

amphetamine (EXP)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dicrotophos (ISO)

dioxygen (ISO)

folic acid (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

indometacin (ISO)

isotretinoin (ISO)

ivermectin (ISO)

methylmercury chloride (ISO)

methylparaben (ISO)

okadaic acid (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

potassium chromate (ISO)

resveratrol (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sunitinib (ISO)

tetrachloromethane (EXP)

tetraphene (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

centrosome (IEA,ISO)

cytoplasm (IBA,IEA)

microtubule (IEA)

mitochondrion (IBA,ISO)

mitotic spindle pole (IBA,IEA,ISO)

spindle (IEA)

spindle microtubule (IBA,IEA,ISO)

spindle pole (IEA)

Molecular Function

microtubule binding (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:18614015	PMID:26316108	PMID:34800366

Genomics

Comparative Map Data

Rmdn1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	37,867,172 - 37,890,826 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	37,867,263 - 38,007,420 (+)	Ensembl				GRCr8
mRatBN7.2	5	33,070,267 - 33,093,922 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	33,070,265 - 33,127,328 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	35,186,377 - 35,209,883 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	36,778,935 - 36,802,441 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	36,718,075 - 36,741,587 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	33,580,891 - 33,604,564 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	33,580,944 - 33,638,165 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	38,235,214 - 38,258,968 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	34,210,399 - 34,233,936 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	32,160,469 - 32,183,998 (+)	NCBI		Celera
Cytogenetic Map	5	q13	NCBI

RMDN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	86,468,266 - 86,514,357 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	86,468,257 - 86,514,357 (-)	Ensembl			hg38	GRCh38
GRCh37	8	87,484,578 - 87,526,586 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	87,553,694 - 87,590,125 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	8	83,679,304 - 83,713,917 (-)	NCBI		Celera
Cytogenetic Map	8	q21.3	NCBI
HuRef	8	82,693,976 - 82,730,379 (-)	NCBI		HuRef
CHM1_1	8	87,526,075 - 87,562,504 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	87,588,507 - 87,634,595 (-)	NCBI		T2T-CHM13v2.0

Rmdn1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	19,575,036 - 19,606,932 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	19,575,162 - 19,606,932 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	19,575,035 - 19,606,932 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	19,575,162 - 19,606,932 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	19,502,214 - 19,534,079 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	19,502,354 - 19,534,079 (+)	NCBI		MGSCv36	mm8
Celera	4	19,337,058 - 19,368,918 (+)	NCBI		Celera
Cytogenetic Map	4	A3	NCBI
cM Map	4	7.56	NCBI

Rmdn1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	4,068,135 - 4,092,788 (-)	Ensembl
ChiLan1.0	NW_004955417	4,067,981 - 4,092,421 (-)	NCBI	ChiLan1.0	ChiLan1.0

RMDN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	103,870,948 - 103,916,804 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	79,409,793 - 79,455,655 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	83,121,882 - 83,209,849 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	85,138,666 - 85,178,896 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	85,138,773 - 85,173,650 (-)	Ensembl			panPan2	panpan1.1

RMDN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	32,624,008 - 32,685,557 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	32,525,554 - 32,674,930 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	32,844,120 - 32,877,992 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	32,779,075 - 32,840,467 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	32,680,619 - 32,829,964 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	32,822,907 - 32,884,243 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	32,847,477 - 32,908,836 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	33,267,771 - 33,329,421 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rmdn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	46,704,357 - 46,744,642 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936544	1,052,568 - 1,088,213 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936544	1,052,416 - 1,088,355 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RMDN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	50,344,909 - 50,389,085 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	50,344,886 - 50,386,187 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	55,260,705 - 55,301,985 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RMDN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	81,657,337 - 81,696,900 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	81,657,533 - 81,691,231 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	59,253,437 - 59,294,483 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rmdn1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624744	5,300,003 - 5,325,081 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624744	5,300,190 - 5,325,170 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rmdn1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	124,116,065 - 124,139,702 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rmdn1
84 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	522
Count of miRNA genes:	264
Interacting mature miRNAs:	324
Transcripts:	ENSRNOT00000036050
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	13731153	43590997	Rat
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	32751649	77751649	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33311673	78311673	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	23671493	79046465	Rat
1300117	Hrtrt8	Heart rate QTL 8	3.49		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	8627230	52665523	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	17576633	62576633	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	14606078	59606078	Rat
1578774	Tcas8	Tongue tumor susceptibility QTL 8	3.47		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	15707451	60707451	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	7065535	74335773	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	33311673	78311673	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	17486080	62486080	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	32751649	77751649	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	26023211	71023211	Rat
2303577	Gluco47	Glucose level QTL 47	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	16520019	61520019	Rat
1549901	Neudeg2	Neurodegradation QTL 2	4	0	nervous system integrity trait (VT:0010566)	mononuclear cell count (CMO:0002119)	5	31130421	48841739	Rat
1641922	Alcrsp8	Alcohol response QTL 8			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	5	17486080	62486080	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	23671493	68671493	Rat
2313085	Bss59	Bone structure and strength QTL 59	2.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	5	8627230	53627230	Rat

Markers in Region

BE121263

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	33,070,813 - 33,070,977 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	33,581,455 - 33,581,618	NCBI	Rnor6.0
Rnor_5.0	5	38,235,859 - 38,236,022	UniSTS	Rnor5.0
RGSC_v3.4	5	34,210,826 - 34,210,989	UniSTS	RGSC3.4
Celera	5	32,160,896 - 32,161,059	UniSTS
RH 3.4 Map	5	166.0	UniSTS
Cytogenetic Map	5	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001031663	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237933	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005504511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098713	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000036050 ⟹ ENSRNOP00000030229

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	37,867,263 - 37,892,344 (+)	Ensembl
mRatBN7.2 Ensembl	5	33,070,355 - 33,093,920 (+)	Ensembl
Rnor_6.0 Ensembl	5	33,581,028 - 33,604,564 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000092054 ⟹ ENSRNOP00000071718

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	37,867,263 - 37,924,246 (+)	Ensembl
mRatBN7.2 Ensembl	5	33,070,265 - 33,127,328 (+)	Ensembl
Rnor_6.0 Ensembl	5	33,580,944 - 33,638,165 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100436 ⟹ ENSRNOP00000082921

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	37,867,291 - 37,890,818 (+)	Ensembl
mRatBN7.2 Ensembl	5	33,070,355 - 33,093,920 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000154005 ⟹ ENSRNOP00000100292

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	37,867,263 - 38,007,420 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000160540 ⟹ ENSRNOP00000111523

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	37,867,263 - 37,915,367 (+)	Ensembl

RefSeq Acc Id:

NM_001031663 ⟹ NP_001026833

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	37,867,291 - 37,890,826 (+)	NCBI
mRatBN7.2	5	33,070,387 - 33,093,922 (+)	NCBI
Rnor_6.0	5	33,581,028 - 33,604,564 (+)	NCBI
Rnor_5.0	5	38,235,214 - 38,258,968 (+)	NCBI
RGSC_v3.4	5	34,210,399 - 34,233,936 (+)	RGD
Celera	5	32,160,469 - 32,183,998 (+)	RGD

Sequence:

show sequence

GTCAGTCATGGCGCTGTCCTCGCGACTGTGGCGTCTTCTCCCTCTGCTACGCGGAGCGGAGCAG
AGCGTGTGTCAGCTGGCGAGGAGCTGGGGCAGCGGTGGGCGCTGTGGCACTTGGGGATTCCGCG
GTTCCGAGGTGACAGGAAACACAAGAGCCTTCAAGAGAGGCCTTTTGTTCTCAGCCTTGTCTTA
TTTGGGTTTTGAAACCTATCAAGTCATTTCTCAAGCTGCTGTGGTTCATGCCACAGCCAAAGTT
GAAGAAATACTTGAGCAAGCAGACTACCTCTATGAAAGTGGAGAAACAGAAAAGCTTTATCAGC
TGCTTACACAGTACAAGGAGAGTGAAGATGTAGAGCTACTGTGGCGGCTGGCACGAGCATCACG
TGACATAGCACAGCTATGTAAGACTTCAGAAGAAGAAAAGAAAGTGTTGTTGTATGAAGCTCTA
GAGTATGCAAAAAGAGCACTAGAAAAAAAGGGGTCAAGCTTTGCTGCTCATAAGTGGTATGCAA
TCTGCATTAGTGATGTTGGGGATTATGAAGGCATCAAGGTTAAGATTGCAAATGCCTATGTCAT
CAAGGAGCACTTTGAGAAAGCAATTGAACTGAACCCTAAAGATGCTACTTCAATTCACCTTATG
GGTATTTGGTGCTATACATTTGCTGAAATGCCTTGGTATCAAAGAAGAATTGCTGAAGTGCTGT
TTGCAAATCCTCCTAGTTCCACCTATGAGGAGGCCTTAAAATACTTTCACAGGGCAGAAGAGGT
GGATCCAAACTTCTACAGCAAAAACTTGCTGCTTTTAGGAAAGACATACTTGAAGCTAAACAAC
AAAAAGCTTGCTGCATTCTGGCTGGTAAAAGCTAAGAGTTACCCAGCACACACAGAAGAAGATA
AACAGATACAGACAGAAGCTGCTCAGTTGCTTACAGGTTTGTGACAAGAACTGAGAACATTTTG
GAGAAGGCAACAACATACCCAATACTTTGTATTTCACTGATTTATAAACATGATACATTAACCA
TCACAATGATTGTATGGCCTTTTTCCCAGTTCTTGTATGTGTGACTATTTTTCAGAATAAATGT
AGAATTTTCTGGGTTTCTTCACAAGTAAATAAAAACTGCCACATTGCCCTAAGAGCGGCAGCAA
TACAGTCCTCTGCTTCAGACAGACGTTTGGAAAACAGTGGTACAGGGTATGTAAATACTGGTCA
CTTCAGGATGAAATGTTTCAAAAGGCTTTGTGAGCAGCTGGCACACGAGGAGATGGCTCTCATG
TTGTAGTCTACTGAAGGCTCTCTTAGAGAAGCCAAGTGTTTATGATGGTGAGGGTTCTGGGCAT
AAAGAACTTAAGTGATGTGTATATTAGAGGCACCCTGAATAAGGGAAAAATCTGCAGAACATCT
TTTTTAAATGTGGTATATCTCCACAGATGGGTTGGATTTGTCACTTGACAAATTGTAATCCTTT
GTAGAATGGACGGACACAGATTTCAGGGTGAAAGGAAATATTTACCAGGCAGAGTACTACAACT
GTGAGTCTGATGTGCCACCACTGTAAACTTACATTTTGCAACAACTAGAGCTGAATGATTATGA
GACTGTGTATGGGTCTATTTTCCCCAAGACATGAGAATTGTAATGTTTTAATAAATTATAGCAA
AATGTGAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006237933 ⟹ XP_006237995

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	37,867,173 - 37,890,826 (+)	NCBI
mRatBN7.2	5	33,070,268 - 33,093,922 (+)	NCBI
Rnor_6.0	5	33,580,891 - 33,604,564 (+)	NCBI
Rnor_5.0	5	38,235,214 - 38,258,968 (+)	NCBI

Sequence:

show sequence

TGGAAACCGAGGCCCGGAAGCTGAGGGAGTGAGGGAGGTGGTGCAGGCGGGCCTTAGGAACTCC
GCTCCAGAGTCGACTTTCGCCCCGCCCCGTTCTGTCAAGTTCGGTAGCTAGTAGTTAGTCAGGC
TGGGAAGCTGTCAGTCATGGCGCTGTCCTCGCGACTGTGGCGTCTTCTCCCTCTGCTACGCGGA
GCGGAGCAGAGCGTGTGTCAGCTGGCGAGGAGCTGGGGCAGCGGTGGGCGCTGTGGCACTTGGG
GATTCCGCGGTTCCGAGGTGACAGGAAACACAAGAGCCTTCAAGAGAGGCCTTTTGTTCTCAGC
CTTGTCTTATTTGGGTTTTGAAACCTATCAAGTCATTTCTCAAGCTGCTGTGGTTCATGCCACA
GCCAAAGTTGAAGAAATACTTGAGCAAGCAGACTACCTCTATGAAAGTGGAGAAACAGAAAAGC
TTTATCAGCTGCTTACACAGTACAAGGAGAGTGAAGATGTAGAGCTACTGTGGCGGCTGGCACG
AGCATCACGTGACATAGCACAGCTATGTAAGACTTCAGAAGAAGAAAAGAAAGTGTTGTTGTAT
GAAGCTCTAGAGTATGCAAAAAGAGCACTAGAAAAAAAGGGGTCAAGCTTTGCTGCTCATAAGA
AAGCAATTGAACTGAACCCTAAAGATGCTACTTCAATTCACCTTATGGGTATTTGGTGCTATAC
ATTTGCTGAAATGCCTTGGTATCAAAGAAGAATTGCTGAAGTGCTGTTTGCAAATCCTCCTAGT
TCCACCTATGAGGAGGCCTTAAAATACTTTCACAGGGCAGAAGAGGTGGATCCAAACTTCTACA
GCAAAAACTTGCTGCTTTTAGGAAAGACATACTTGAAGCTAAACAACAAAAAGCTTGCTGCATT
CTGGCTGGTAAAAGCTAAGAGTTACCCAGCACACACAGAAGAAGATAAACAGATACAGACAGAA
GCTGCTCAGTTGCTTACAGGTTTGTGACAAGAACTGAGAACATTTTGGAGAAGGCAACAACATA
CCCAATACTTTGTATTTCACTGATTTATAAACATGATACATTAACCATCACAATGATTGTATGG
CCTTTTTCCCAGTTCTTGTATGTGTGACTATTTTTCAGAATAAATGTAGAATTTTCTGGGTTTC
TTCACAAGTAAATAAAAACTGCCACATTGCCCTAAGAGCGGCAGCAATACAGTCCTCTGCTTCA
GACAGACGTTTGGAAAACAGTGGTACAGGGTATGTAAATACTGGTCACTTCAGGATGAAATGTT
TCAAAAGGCTTTGTGAGCAGCTGGCACACGAGGAGATGGCTCTCATGTTGTAGTCTACTGAAGG
CTCTCTTAGAGAAGCCAAGTGTTTATGATGGTGAGGGTTCTGGGCATAAAGAACTTAAGTGATG
TGTATATTAGAGGCACCCTGAATAAGGGAAAAATCTGCAGAACATCTTTTTTAAATGTGGTATA
TCTCCACAGATGGGTTGGATTTGTCACTTGACAAATTGTAATCCTTTGTAGAATGGACGGACAC
AGATTTCAGGGTGAAAGGAAATATTTACCAGGCAGAGTACTACAACTGTGAGTCTGATGTGCCA
CCACTGTAAACTTACATTTTGCAACAACTAGAGCTGAATGATTATGAGACTGTGTATGGGTCTA
TTTTCCCCAAGACATGAGAATTGTAATGTTTTAATAAATTATAGCAAAATGTG

hide sequence

RefSeq Acc Id:

XR_005504511

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	37,867,172 - 37,889,459 (+)	NCBI
mRatBN7.2	5	33,070,267 - 33,092,549 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001026833	(Get FASTA)	NCBI Sequence Viewer
	XP_006237995	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98713	(Get FASTA)	NCBI Sequence Viewer
	EDL98497	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030229
	ENSRNOP00000030229.3
	ENSRNOP00000082921
GenBank Protein	Q4G069	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001026833 ⟸ NM_001031663

- UniProtKB:

Q4G069 (UniProtKB/Swiss-Prot), A6IIC7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALSSRLWRLLPLLRGAEQSVCQLARSWGSGGRCGTWGFRGSEVTGNTRAFKRGLLFSALSYLG
FETYQVISQAAVVHATAKVEEILEQADYLYESGETEKLYQLLTQYKESEDVELLWRLARASRDI
AQLCKTSEEEKKVLLYEALEYAKRALEKKGSSFAAHKWYAICISDVGDYEGIKVKIANAYVIKE
HFEKAIELNPKDATSIHLMGIWCYTFAEMPWYQRRIAEVLFANPPSSTYEEALKYFHRAEEVDP
NFYSKNLLLLGKTYLKLNNKKLAAFWLVKAKSYPAHTEEDKQIQTEAAQLLTGL

hide sequence

RefSeq Acc Id:	XP_006237995 ⟸ XM_006237933
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6G831 (UniProtKB/TrEMBL), A6IIC7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALSSRLWRLLPLLRGAEQSVCQLARSWGSGGRCGTWGFRGSEVTGNTRAFKRGLLFSALSYLG FETYQVISQAAVVHATAKVEEILEQADYLYESGETEKLYQLLTQYKESEDVELLWRLARASRDI AQLCKTSEEEKKVLLYEALEYAKRALEKKGSSFAAHKKAIELNPKDATSIHLMGIWCYTFAEMP WYQRRIAEVLFANPPSSTYEEALKYFHRAEEVDPNFYSKNLLLLGKTYLKLNNKKLAAFWLVKA KSYPAHTEEDKQIQTEAAQLLTGL hide sequence

Ensembl Acc Id:

ENSRNOP00000071718 ⟸ ENSRNOT00000092054

Ensembl Acc Id:

ENSRNOP00000030229 ⟸ ENSRNOT00000036050

Ensembl Acc Id:

ENSRNOP00000082921 ⟸ ENSRNOT00000100436

Ensembl Acc Id:

ENSRNOP00000111523 ⟸ ENSRNOT00000160540

Ensembl Acc Id:

ENSRNOP00000100292 ⟸ ENSRNOT00000154005

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4G069-F1-model_v2	AlphaFold	Q4G069	1-310	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693602

Promoter ID:

EPDNEW_R4113

Type:

initiation region

Name:

Rmdn1_1

Description:

regulator of microtubule dynamics 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	33,581,004 - 33,581,064	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563085	AgrOrtholog
BioCyc Gene	G2FUF-41839	BioCyc
Ensembl Genes	ENSRNOG00000025145	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000036050	ENTREZGENE
	ENSRNOT00000036050.5	UniProtKB/Swiss-Prot
	ENSRNOT00000100436	ENTREZGENE
Gene3D-CATH	1.25.40.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7122806	IMAGE-MGC_LOAD
	IMAGE:7322407	IMAGE-MGC_LOAD
InterPro	RMD1-3_a_helical_rpt	UniProtKB/Swiss-Prot
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:500419	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:112702	IMAGE-MGC_LOAD
	MGC:95033	IMAGE-MGC_LOAD
NCBI Gene	500419	ENTREZGENE
PANTHER	REGULATOR OF MICROTUBULE DYNAMICS PROTEIN	UniProtKB/Swiss-Prot
	REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1	UniProtKB/Swiss-Prot
Pfam	RMD1-3	UniProtKB/Swiss-Prot
PhenoGen	Rmdn1	PhenoGen
RatGTEx	ENSRNOG00000025145	RatGTEx
Superfamily-SCOP	SSF48452	UniProtKB/Swiss-Prot
UniProt	A0A0G2K167_RAT	UniProtKB/TrEMBL
	A0A8I6G831	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L8S6_RAT	UniProtKB/TrEMBL
	A0ABK0M4N1_RAT	UniProtKB/TrEMBL
	A6IIC7	ENTREZGENE, UniProtKB/TrEMBL
	Q4G069	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-01-17	Rmdn1	regulator of microtubule dynamics 1	Fam82b	family with sequence similarity 82, member B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Fam82b	family with sequence similarity 82, member B	LOC500419	similar to RIKEN cDNA 2410005O16	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	LOC500419	similar to RIKEN cDNA 2410005O16			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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