Epb41l4b (erythrocyte membrane protein band 4.1 like 4B) - Rat Genome Database

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Gene: Epb41l4b (erythrocyte membrane protein band 4.1 like 4B) Rattus norvegicus
Analyze
Symbol: Epb41l4b
Name: erythrocyte membrane protein band 4.1 like 4B
RGD ID: 1562988
Description: Predicted to enable cytoskeletal protein binding activity. Predicted to be involved in several processes, including actomyosin structure organization; positive regulation of keratinocyte migration; and wound healing. Predicted to be located in apical part of cell; cytosol; and plasma membrane. Predicted to be active in cytoskeleton. Orthologous to human EPB41L4B (erythrocyte membrane protein band 4.1 like 4B); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: band 4.1-like protein 4B; LOC500464; RGD1562988; similar to EHM2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8576,486,886 - 76,647,752 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl576,486,902 - 76,647,752 (-)EnsemblGRCr8
mRatBN7.2571,691,706 - 71,852,583 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl571,694,331 - 71,851,990 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx573,579,659 - 73,742,868 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0575,410,983 - 75,571,368 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0575,383,056 - 75,543,452 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd576,533,804 - 76,696,999 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive578,200,413 - 78,363,612 (-)NCBILyon_Normotensive
Lyon_Hypertensive577,422,249 - 77,585,441 (-)NCBILyon_Hypertensive
F344_StmMcwi571,299,816 - 71,459,874 (-)NCBIF344_StmMcwi
Rnor_6.0574,030,950 - 74,192,275 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl574,030,882 - 74,191,167 (-)Ensemblrn6Rnor6.0
Rnor_5.0578,259,811 - 78,344,848 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4574,972,597 - 75,059,096 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera570,548,863 - 70,608,478 (-)NCBICelera
Celera570,618,652 - 70,703,659 (-)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
CGP 52608  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
glyphosate  (EXP)
indometacin  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
maneb  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
paraquat  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylephrine  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tremolite asbestos  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:22006950   PMID:23664528  


Genomics

Comparative Map Data
Epb41l4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8576,486,886 - 76,647,752 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl576,486,902 - 76,647,752 (-)EnsemblGRCr8
mRatBN7.2571,691,706 - 71,852,583 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl571,694,331 - 71,851,990 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx573,579,659 - 73,742,868 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0575,410,983 - 75,571,368 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0575,383,056 - 75,543,452 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd576,533,804 - 76,696,999 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive578,200,413 - 78,363,612 (-)NCBILyon_Normotensive
Lyon_Hypertensive577,422,249 - 77,585,441 (-)NCBILyon_Hypertensive
F344_StmMcwi571,299,816 - 71,459,874 (-)NCBIF344_StmMcwi
Rnor_6.0574,030,950 - 74,192,275 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl574,030,882 - 74,191,167 (-)Ensemblrn6Rnor6.0
Rnor_5.0578,259,811 - 78,344,848 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4574,972,597 - 75,059,096 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera570,548,863 - 70,608,478 (-)NCBICelera
Celera570,618,652 - 70,703,659 (-)NCBICelera
Cytogenetic Map5q24NCBI
EPB41L4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389109,171,974 - 109,321,059 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9109,171,463 - 109,321,067 (-)Ensemblhg38GRCh38
GRCh379111,934,254 - 112,083,339 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369110,974,075 - 111,122,842 (-)NCBIBuild 36Build 36hg18NCBI36
Celera982,433,463 - 82,582,331 (-)NCBICelera
Cytogenetic Map9q31.3NCBI
HuRef981,534,383 - 81,682,900 (-)NCBIHuRef
CHM1_19112,080,755 - 112,230,021 (-)NCBICHM1_1
T2T-CHM13v2.09121,341,055 - 121,490,407 (-)NCBIT2T-CHM13v2.0
Epb41l4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39456,991,977 - 57,143,753 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl456,991,972 - 57,143,437 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38456,991,972 - 57,143,168 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl456,991,972 - 57,143,437 (-)Ensemblmm10GRCm38
MGSCv37457,074,598 - 57,156,028 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36457,089,660 - 57,251,234 (-)NCBIMGSCv36mm8
Celera456,971,790 - 57,053,159 (-)NCBICelera
Cytogenetic Map4B3NCBI
cM Map431.66NCBI
Epb41l4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541917,686,882 - 17,823,605 (+)Ensembl
ChiLan1.0NW_00495541917,686,096 - 17,821,884 (+)NCBIChiLan1.0ChiLan1.0
EPB41L4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21130,086,890 - 30,235,815 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1930,089,255 - 30,239,746 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0980,324,948 - 80,401,283 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19108,496,690 - 108,650,645 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9108,499,267 - 108,604,576 (-)EnsemblpanPan2panpan1.1
EPB41L4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11164,312,716 - 64,439,117 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1164,312,802 - 64,407,412 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1162,713,675 - 62,840,170 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01165,446,475 - 65,573,331 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1165,446,078 - 65,574,026 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11163,965,575 - 64,091,945 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01163,987,800 - 64,114,603 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01164,678,447 - 64,805,309 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Epb41l4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947179,546,685 - 179,684,395 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365593,587,379 - 3,716,883 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365593,582,190 - 3,717,407 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPB41L4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1250,226,595 - 250,368,846 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11250,226,592 - 250,368,897 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21280,755,888 - 280,879,154 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPB41L4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11230,230,214 - 30,381,295 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1230,230,724 - 30,382,212 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603512,303,113 - 12,455,585 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Epb41l4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247582,221,581 - 2,362,458 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247582,221,600 - 2,361,572 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Epb41l4b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1194,472,586 - 94,627,710 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Epb41l4b
590 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:67
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000015114
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)573779642103472210Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat

Markers in Region
RH128855  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2571,766,321 - 71,766,515 (+)MAPPERmRatBN7.2
Rnor_6.0574,105,550 - 74,105,743NCBIRnor6.0
Rnor_5.0578,259,870 - 78,260,063UniSTSRnor5.0
RGSC_v3.4574,972,656 - 74,972,849UniSTSRGSC3.4
Celera570,618,711 - 70,618,904UniSTS
RH 3.4 Map5482.1UniSTS
Cytogenetic Map5q24UniSTS
AU048092  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2571,847,244 - 71,847,396 (+)MAPPERmRatBN7.2
Rnor_6.0574,186,434 - 74,186,585NCBIRnor6.0
Rnor_5.0578,340,253 - 78,340,404UniSTSRnor5.0
RGSC_v3.4575,054,501 - 75,054,652UniSTSRGSC3.4
Celera570,699,152 - 70,699,303UniSTS
Cytogenetic Map5q24UniSTS
AU049474  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8576,639,545 - 76,639,765 (+)Marker Load Pipeline
mRatBN7.2571,844,376 - 71,844,596 (+)MAPPERmRatBN7.2
Rnor_6.0574,183,566 - 74,183,785NCBIRnor6.0
Rnor_5.0578,337,385 - 78,337,604UniSTSRnor5.0
RGSC_v3.4575,051,633 - 75,051,852UniSTSRGSC3.4
Celera570,696,288 - 70,696,503UniSTS
Cytogenetic Map5q24UniSTS
MARC_21252-21253:1032892750:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2571,780,900 - 71,781,164 (+)MAPPERmRatBN7.2
Rnor_6.0574,120,129 - 74,120,392NCBIRnor6.0
Rnor_5.0578,274,449 - 78,274,712UniSTSRnor5.0
RGSC_v3.4574,987,235 - 74,987,498UniSTSRGSC3.4
Celera570,633,284 - 70,633,547UniSTS
Cytogenetic Map5q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 158 91 90 59 32 59 6 296 132 11 137 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000088169   ⟹   ENSRNOP00000068924
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl576,560,579 - 76,647,752 (-)Ensembl
mRatBN7.2 Ensembl571,766,264 - 71,851,990 (-)Ensembl
Rnor_6.0 Ensembl574,105,492 - 74,191,167 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090366   ⟹   ENSRNOP00000072639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl576,486,902 - 76,647,752 (-)Ensembl
mRatBN7.2 Ensembl571,694,331 - 71,851,990 (-)Ensembl
Rnor_6.0 Ensembl574,030,882 - 74,190,991 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102034   ⟹   ENSRNOP00000088752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl576,530,553 - 76,647,752 (-)Ensembl
mRatBN7.2 Ensembl571,694,331 - 71,851,990 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112787   ⟹   ENSRNOP00000086223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl576,560,579 - 76,647,752 (-)Ensembl
mRatBN7.2 Ensembl571,766,264 - 71,851,990 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000147948   ⟹   ENSRNOP00000101921
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl576,486,902 - 76,647,752 (-)Ensembl
RefSeq Acc Id: NM_001127565   ⟹   NP_001121037
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,560,579 - 76,647,752 (-)NCBI
mRatBN7.2571,765,409 - 71,852,583 (-)NCBI
Dahl_SR_JrHsd576,609,862 - 76,696,999 (-)NCBI
Lyon_Normotensive578,276,470 - 78,363,612 (-)NCBI
Lyon_Hypertensive577,498,302 - 77,585,441 (-)NCBI
F344_StmMcwi571,373,066 - 71,459,874 (-)NCBI
Rnor_6.0574,105,491 - 74,191,167 (-)NCBI
Rnor_5.0578,259,811 - 78,344,848 (-)NCBI
RGSC_v3.4574,972,597 - 75,059,096 (-)RGD
Celera570,618,652 - 70,703,659 (-)RGD
Sequence:
RefSeq Acc Id: NM_001401792   ⟹   NP_001388721
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,486,891 - 76,647,752 (-)NCBI
mRatBN7.2571,691,706 - 71,852,583 (-)NCBI
Dahl_SR_JrHsd576,533,804 - 76,696,999 (-)NCBI
Lyon_Normotensive578,200,413 - 78,363,612 (-)NCBI
Lyon_Hypertensive577,422,249 - 77,585,441 (-)NCBI
F344_StmMcwi571,299,816 - 71,459,874 (-)NCBI
RefSeq Acc Id: XM_039110571   ⟹   XP_038966499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,486,886 - 76,647,698 (-)NCBI
mRatBN7.2571,691,706 - 71,852,039 (-)NCBI
RefSeq Acc Id: XM_039110572   ⟹   XP_038966500
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,486,886 - 76,647,698 (-)NCBI
mRatBN7.2571,691,706 - 71,852,039 (-)NCBI
RefSeq Acc Id: XM_039110573   ⟹   XP_038966501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,486,886 - 76,647,697 (-)NCBI
mRatBN7.2571,691,706 - 71,852,039 (-)NCBI
RefSeq Acc Id: XM_063288229   ⟹   XP_063144299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,535,390 - 76,647,696 (-)NCBI
RefSeq Acc Id: XM_063288230   ⟹   XP_063144300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,486,886 - 76,557,595 (-)NCBI
RefSeq Acc Id: XR_005504513
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,538,082 - 76,647,692 (-)NCBI
mRatBN7.2571,742,924 - 71,852,039 (-)NCBI
RefSeq Acc Id: XR_010066451
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8576,519,540 - 76,647,693 (-)NCBI
RefSeq Acc Id: NP_001121037   ⟸   NM_001127565
- Peptide Label: isoform 2
- UniProtKB: B2RYE5 (UniProtKB/Swiss-Prot),   A0A0G2JU16 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072639   ⟸   ENSRNOT00000090366
Ensembl Acc Id: ENSRNOP00000068924   ⟸   ENSRNOT00000088169
RefSeq Acc Id: XP_038966500   ⟸   XM_039110572
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K3H4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966501   ⟸   XM_039110573
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038966499   ⟸   XM_039110571
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000088752   ⟸   ENSRNOT00000102034
Ensembl Acc Id: ENSRNOP00000086223   ⟸   ENSRNOT00000112787
RefSeq Acc Id: NP_001388721   ⟸   NM_001401792
- Peptide Label: isoform 1
- UniProtKB: A0A8I6AAH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144300   ⟸   XM_063288230
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063144299   ⟸   XM_063288229
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JU16 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101921   ⟸   ENSRNOT00000147948
Protein Domains
FERM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RYE5-F1-model_v2 AlphaFold B2RYE5 1-527 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693756
Promoter ID:EPDNEW_R4281
Type:multiple initiation site
Name:Epb41l4b_1
Description:erythrocyte membrane protein band 4.1 like 4B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0574,191,118 - 74,191,178EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562988 AgrOrtholog
BioCyc Gene G2FUF-41212 BioCyc
Ensembl Genes ENSRNOG00000056550 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000088169 ENTREZGENE
  ENSRNOT00000088169.2 UniProtKB/Swiss-Prot
  ENSRNOT00000090366 ENTREZGENE
  ENSRNOT00000102034 ENTREZGENE
  ENSRNOT00000147948 ENTREZGENE
Gene3D-CATH 1.20.80.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5599589 IMAGE-MGC_LOAD
InterPro Band4.1-like4B UniProtKB/Swiss-Prot
  Band_41_domain UniProtKB/Swiss-Prot
  Ez/rad/moesin-like UniProtKB/Swiss-Prot
  FERM-adjacent UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_CS UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  FERM_PH-like_C UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report rno:500464 UniProtKB/Swiss-Prot
MGC_CLONE MGC:188486 IMAGE-MGC_LOAD
NCBI Gene 500464 ENTREZGENE
PANTHER 4.1 G PROTEIN UniProtKB/Swiss-Prot
  PTHR23280:SF18 UniProtKB/Swiss-Prot
Pfam FERM_C UniProtKB/Swiss-Prot
  FERM_M UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  PF08736 UniProtKB/Swiss-Prot
PhenoGen Epb41l4b PhenoGen
PRINTS BAND41 UniProtKB/Swiss-Prot
  ERMFAMILY UniProtKB/Swiss-Prot
PROSITE FERM_2 UniProtKB/Swiss-Prot
  FERM_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000056550 RatGTEx
SMART B41 UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
  SM01195 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF47031 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
UniProt A0A0G2JU16 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K3H4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A1T8_RAT UniProtKB/TrEMBL
  A0A8I6AAH9 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LB09_RAT UniProtKB/TrEMBL
  B2RYE5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 RGD1562988  similar to EHM2   RGD1562988_predicted  similar to EHM2 (predicted)  'predicted' is removed 2292626 APPROVED
2008-01-09 RGD1562988_predicted  similar to EHM2 (predicted)  LOC682100  similar to erythrocyte membrane protein band 4.1 like 4B isoform 2  Data merged from RGD:1586984 1643240 APPROVED
2006-11-19 LOC682100  similar to erythrocyte membrane protein band 4.1 like 4B isoform 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1562988_predicted  similar to EHM2 (predicted)  LOC500464  similar to EHM2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500464  similar to EHM2      Symbol and Name status set to provisional 70820 PROVISIONAL