Spsb4 (splA/ryanodine receptor domain and SOCS box containing 4) - Rat Genome Database

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Gene: Spsb4 (splA/ryanodine receptor domain and SOCS box containing 4) Rattus norvegicus
Analyze
Symbol: Spsb4
Name: splA/ryanodine receptor domain and SOCS box containing 4
RGD ID: 1562307
Description: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in several processes, including positive regulation of protein polyubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in cytosol. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC300950; RGD1562307; similar to SPRY domain-containing SOCS box 4; SPRY domain-containing SOCS box protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88106,416,039 - 106,489,271 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8106,416,040 - 106,489,271 (-)EnsemblGRCr8
mRatBN7.2897,536,519 - 97,609,757 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl897,536,520 - 97,609,787 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8103,204,973 - 103,278,112 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08101,404,227 - 101,477,360 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0899,243,182 - 99,316,308 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08104,840,939 - 104,912,959 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8104,840,940 - 104,912,959 (-)Ensemblrn6Rnor6.0
Rnor_5.08104,287,498 - 104,359,356 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48102,034,525 - 102,107,618 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera896,977,033 - 97,049,836 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
all-trans-retinoic acid  (EXP)
amitrole  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
decabromodiphenyl ether  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodimethylamine  (EXP)
nitrogen dioxide  (ISO)
okadaic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
resveratrol  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21199876   PMID:26392558   PMID:28931592  


Genomics

Comparative Map Data
Spsb4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88106,416,039 - 106,489,271 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8106,416,040 - 106,489,271 (-)EnsemblGRCr8
mRatBN7.2897,536,519 - 97,609,757 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl897,536,520 - 97,609,787 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8103,204,973 - 103,278,112 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08101,404,227 - 101,477,360 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0899,243,182 - 99,316,308 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08104,840,939 - 104,912,959 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8104,840,940 - 104,912,959 (-)Ensemblrn6Rnor6.0
Rnor_5.08104,287,498 - 104,359,356 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48102,034,525 - 102,107,618 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera896,977,033 - 97,049,836 (-)NCBICelera
Cytogenetic Map8q31NCBI
SPSB4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383141,051,347 - 141,148,611 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3141,050,744 - 141,148,613 (+)Ensemblhg38GRCh38
GRCh373140,770,189 - 140,867,453 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363142,253,433 - 142,350,143 (+)NCBIBuild 36Build 36hg18NCBI36
Celera3139,194,129 - 139,290,840 (+)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3138,145,605 - 138,242,314 (+)NCBIHuRef
CHM1_13140,733,736 - 140,830,404 (+)NCBICHM1_1
T2T-CHM13v2.03143,798,863 - 143,896,164 (+)NCBIT2T-CHM13v2.0
Spsb4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39996,825,535 - 96,900,408 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl996,825,535 - 96,900,896 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38996,943,482 - 97,018,355 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl996,943,482 - 97,018,843 (-)Ensemblmm10GRCm38
MGSCv37996,843,901 - 96,918,774 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36996,752,834 - 96,827,707 (-)NCBIMGSCv36mm8
Celera996,503,220 - 96,578,054 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map950.74NCBI
Spsb4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555084,539,516 - 4,615,439 (-)Ensembl
ChiLan1.0NW_0049555084,539,531 - 4,615,439 (-)NCBIChiLan1.0ChiLan1.0
SPSB4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22138,961,906 - 139,058,518 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13138,966,638 - 139,063,250 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03138,085,136 - 138,181,747 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13145,682,533 - 145,779,049 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3145,682,533 - 145,779,049 (+)EnsemblpanPan2panpan1.1
SPSB4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12336,998,124 - 37,082,576 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2336,997,705 - 37,077,401 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2336,987,084 - 37,068,486 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02337,528,830 - 37,610,138 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2337,528,801 - 37,610,136 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12337,210,665 - 37,292,472 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02337,284,991 - 37,366,350 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02337,527,473 - 37,608,794 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Spsb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560276,214,048 - 76,281,647 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365402,953,831 - 3,021,485 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365402,953,837 - 3,021,430 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPSB4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1381,867,740 - 81,926,762 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11381,849,908 - 81,926,764 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21389,692,304 - 89,769,847 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPSB4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11549,442,817 - 49,529,654 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1549,442,864 - 49,515,357 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604122,387,229 - 22,474,610 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spsb4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473017,692,959 - 17,774,497 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473017,692,124 - 17,774,321 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Spsb4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1888,392,017 - 88,462,914 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Spsb4
776 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:271
Count of miRNA genes:159
Interacting mature miRNAs:185
Transcripts:ENSRNOT00000017363
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)897492344116428905Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
AW535059  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2897,597,443 - 97,597,656 (+)MAPPERmRatBN7.2
Rnor_6.08104,900,645 - 104,900,857NCBIRnor6.0
Rnor_5.08104,347,042 - 104,347,254UniSTSRnor5.0
RGSC_v3.48102,095,305 - 102,095,517UniSTSRGSC3.4
Celera897,037,522 - 97,037,734UniSTS
RH 3.4 Map81051.0UniSTS
Cytogenetic Map8q31UniSTS
AU048745  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q32UniSTS
Cytogenetic Map13q24UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map13q26UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map5q21UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map2q11UniSTS
Cytogenetic Map1q54UniSTS
Cytogenetic Map1q36UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map13q13UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map8q31UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map13p13UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map10q31UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map3q24UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map3p13UniSTS
AA963566  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map8927.49UniSTS
Cytogenetic Map8q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 146 91 90 59 40 59 6 303 139 9 125 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017363   ⟹   ENSRNOP00000017363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8106,416,040 - 106,489,271 (-)Ensembl
mRatBN7.2 Ensembl897,536,520 - 97,609,787 (-)Ensembl
Rnor_6.0 Ensembl8104,840,940 - 104,912,959 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000150739   ⟹   ENSRNOP00000108476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8106,455,729 - 106,488,762 (-)Ensembl
RefSeq Acc Id: NM_001106849   ⟹   NP_001100319
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88106,416,039 - 106,489,271 (-)NCBI
mRatBN7.2897,536,519 - 97,609,757 (-)NCBI
Rnor_6.08104,840,939 - 104,912,959 (-)NCBI
Rnor_5.08104,287,498 - 104,359,356 (-)NCBI
RGSC_v3.48102,034,525 - 102,107,618 (-)RGD
Celera896,977,033 - 97,049,836 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100319 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68912 (Get FASTA)   NCBI Sequence Viewer  
  EDL77484 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017363
  ENSRNOP00000017363.5
  ENSRNOP00000108476.1
RefSeq Acc Id: NP_001100319   ⟸   NM_001106849
- UniProtKB: B5DF38 (UniProtKB/TrEMBL),   F7ER07 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017363   ⟸   ENSRNOT00000017363
Ensembl Acc Id: ENSRNOP00000108476   ⟸   ENSRNOT00000150739
Protein Domains
B30.2/SPRY   SOCS box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DF38-F1-model_v2 AlphaFold B5DF38 1-273 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696196
Promoter ID:EPDNEW_R6721
Type:initiation region
Name:Spsb4_1
Description:splA/ryanodine receptor domain and SOCS box containing 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08104,913,046 - 104,913,106EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562307 AgrOrtholog
BioCyc Gene G2FUF-29429 BioCyc
Ensembl Genes ENSRNOG00000012862 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017363 ENTREZGENE
  ENSRNOT00000017363.7 UniProtKB/TrEMBL
  ENSRNOT00000150739.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  SOCS box UniProtKB/TrEMBL
InterPro B30.2/SPRY_sf UniProtKB/TrEMBL
  B302 UniProtKB/TrEMBL
  ConA-like_dom UniProtKB/TrEMBL
  FBXO45-Fsn/SPSB_families UniProtKB/TrEMBL
  SOCS_box_dom_like UniProtKB/TrEMBL
  SOCS_C UniProtKB/TrEMBL
  SPRY_rcpt UniProtKB/TrEMBL
KEGG Report rno:300950 UniProtKB/TrEMBL
NCBI Gene 300950 ENTREZGENE
PANTHER SPRY DOMAIN CONTAINING SOCS BOX PROTEIN UniProtKB/TrEMBL
  SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4 UniProtKB/TrEMBL
Pfam SOCS_box UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
PhenoGen Spsb4 PhenoGen
PROSITE B302_SPRY UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012862 RatGTEx
SMART SOCS_box UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
  SSF158235 UniProtKB/TrEMBL
UniProt A0ABK0LU97_RAT UniProtKB/TrEMBL
  B5DF38 ENTREZGENE, UniProtKB/TrEMBL
  F7ER07 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Spsb4  splA/ryanodine receptor domain and SOCS box containing 4   Spsb4_predicted  splA/ryanodine receptor domain and SOCS box containing 4 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Spsb4_predicted  splA/ryanodine receptor domain and SOCS box containing 4 (predicted)  RGD1562307_predicted  similar to SPRY domain-containing SOCS box 4 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1562307_predicted  similar to SPRY domain-containing SOCS box 4 (predicted)  LOC300950  similar to SPRY domain-containing SOCS box 4  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC300950  similar to SPRY domain-containing SOCS box 4      Symbol and Name status set to provisional 70820 PROVISIONAL