Ctnna3 (catenin alpha 3) - Rat Genome Database

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Gene: Ctnna3 (catenin alpha 3) Rattus norvegicus
Analyze
Symbol: Ctnna3
Name: catenin alpha 3
RGD ID: 1562230
Description: Predicted to enable actin filament binding activity and beta-catenin binding activity. Predicted to be involved in cell migration and regulation of heart contraction. Predicted to be located in lamellipodium. Predicted to be active in adherens junction and fascia adherens. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular dysplasia 13. Orthologous to human CTNNA3 (catenin alpha 3); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; endometrial cancer pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07044900.1; catenin (cadherin associated protein), alpha 3; catenin alpha-3; Catna3; LOC361839; MGC188744; rCG61001-like; RGD1559455; RGD1562230; similar to catenin alpha 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82023,613,016 - 25,198,699 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2023,613,016 - 25,198,805 (-)EnsemblGRCr8
mRatBN7.22023,614,469 - 25,200,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2023,623,560 - 25,199,978 (-)EnsemblmRatBN7.2
Rnor_6.02025,063,124 - 26,640,428 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2026,516,836 - 26,589,209 (-)Ensemblrn6Rnor6.0
Rnor_5.02027,131,441 - 28,684,032 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42025,842,315 - 26,947,108 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2024,950,408 - 26,462,542 (-)NCBICelera
Cytogenetic Map20p11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. CTNNA3 (α-catenin) gene variants are associated with diisocyanate asthma: a replication study in a Caucasian worker population. Bernstein DI, etal., Toxicol Sci. 2013 Jan;131(1):242-6. doi: 10.1093/toxsci/kfs272. Epub 2012 Sep 13.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis. Kim SH, etal., Clin Exp Allergy. 2009 Feb;39(2):203-12. doi: 10.1111/j.1365-2222.2008.03117.x.
4. CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies. McGeachie MJ, etal., J Allergy Clin Immunol. 2015 Dec;136(6):1503-10. doi: 10.1016/j.jaci.2015.04.039. Epub 2015 Jun 12.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Polymorphisms in recent GWA identified asthma genes CA10, SGK493, and CTNNA3 are associated with disease severity and treatment response in childhood asthma. Perin P and Potočnik U, Immunogenetics. 2014 Mar;66(3):143-51. doi: 10.1007/s00251-013-0755-0. Epub 2014 Jan 10.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11590244   PMID:12477932   PMID:14657280   PMID:15632090   PMID:17535849   PMID:19129494   PMID:23136403   PMID:31505169  


Genomics

Comparative Map Data
Ctnna3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82023,613,016 - 25,198,699 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2023,613,016 - 25,198,805 (-)EnsemblGRCr8
mRatBN7.22023,614,469 - 25,200,026 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2023,623,560 - 25,199,978 (-)EnsemblmRatBN7.2
Rnor_6.02025,063,124 - 26,640,428 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2026,516,836 - 26,589,209 (-)Ensemblrn6Rnor6.0
Rnor_5.02027,131,441 - 28,684,032 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42025,842,315 - 26,947,108 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2024,950,408 - 26,462,542 (-)NCBICelera
Cytogenetic Map20p11NCBI
CTNNA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381065,912,523 - 67,763,594 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1065,912,457 - 67,763,637 (-)Ensemblhg38GRCh38
GRCh371067,672,281 - 69,455,953 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361067,349,937 - 69,125,933 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341067,349,937 - 69,125,933NCBI
Celera1060,952,569 - 62,730,826 (-)NCBICelera
Cytogenetic Map10q21.3NCBI
HuRef1061,677,649 - 63,454,766 (-)NCBIHuRef
CHM1_11067,961,493 - 69,737,768 (-)NCBICHM1_1
T2T-CHM13v2.01066,775,664 - 68,632,045 (-)NCBIT2T-CHM13v2.0
Ctnna3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391063,265,877 - 64,841,174 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1063,265,877 - 64,839,446 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381063,430,098 - 65,003,667 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1063,430,098 - 65,003,667 (+)Ensemblmm10GRCm38
MGSCv371062,892,846 - 64,466,415 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361062,825,455 - 64,398,299 (+)NCBIMGSCv36mm8
Celera1064,530,270 - 66,095,505 (+)NCBICelera
Cytogenetic Map10B4- B5.1NCBI
cM Map1032.57NCBI
Ctnna3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542518,628,961 - 20,087,647 (-)Ensembl
ChiLan1.0NW_00495542518,623,645 - 20,126,200 (-)NCBIChiLan1.0ChiLan1.0
CTNNA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2878,066,982 - 79,827,494 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11078,072,306 - 79,832,818 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01062,388,454 - 64,177,116 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11064,712,491 - 66,460,336 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1064,712,576 - 66,442,238 (-)EnsemblpanPan2panpan1.1
CTNNA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1417,364,121 - 19,035,836 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl417,372,245 - 19,017,093 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha417,591,055 - 19,164,102 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0417,635,105 - 19,300,514 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl417,640,624 - 19,300,489 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1417,507,139 - 19,184,802 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0417,734,430 - 19,402,955 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0418,082,469 - 19,749,039 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ctnna3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721361,989,665 - 63,613,571 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493652110,482,434 - 10,936,554 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTNNA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1469,195,961 - 70,938,204 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11469,195,231 - 70,974,543 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21475,079,730 - 76,379,603 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTNNA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1963,669,561 - 65,406,737 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604824,490,435 - 26,255,182 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctnna3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624754285,857 - 2,034,582 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624754285,469 - 2,182,218 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ctnna3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11821,725,648 - 23,220,892 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ctnna3
11464 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:173
Count of miRNA genes:132
Interacting mature miRNAs:146
Transcripts:ENSRNOT00000049437, ENSRNOT00000057950
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804392029865039Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)202074558556021148Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
D20Rat13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,030,597 - 24,030,713 (+)MAPPERmRatBN7.2
Rnor_6.02025,499,650 - 25,499,765NCBIRnor6.0
Rnor_5.02027,567,584 - 27,567,699UniSTSRnor5.0
Celera2025,363,389 - 25,363,504UniSTS
FHH x ACI Map2012.4099RGD
FHH x ACI Map2012.4099UniSTS
Cytogenetic Map20p11-q11UniSTS
D7Rat16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27102,920,123 - 102,920,263 (+)MAPPERmRatBN7.2
Rnor_6.07112,204,378 - 112,204,517NCBIRnor6.0
Rnor_5.07112,143,411 - 112,143,550UniSTSRnor5.0
RGSC_v3.47108,647,237 - 108,647,376UniSTSRGSC3.4
RGSC_v3.47108,647,236 - 108,647,376RGDRGSC3.4
Celera2025,557,526 - 25,557,946UniSTS
RGSC_v3.17108,681,467 - 108,681,606RGD
RH 3.4 Map7709.6RGD
RH 3.4 Map7709.6UniSTS
RH 2.0 Map7607.2RGD
SHRSP x BN Map759.07RGD
FHH x ACI Map750.06RGD
Cytogenetic Map20p11-q11UniSTS
D20Rat7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,963,389 - 24,963,524 (+)MAPPERmRatBN7.2
Rnor_6.02026,447,820 - 26,447,954NCBIRnor6.0
Rnor_5.02028,510,783 - 28,510,917UniSTSRnor5.0
RGSC_v3.42026,064,461 - 26,064,596RGDRGSC3.4
RGSC_v3.42026,064,462 - 26,064,596UniSTSRGSC3.4
Celera2026,274,277 - 26,274,411UniSTS
RGSC_v3.12026,078,261 - 26,078,396RGD
SHRSP x BN Map2021.46UniSTS
SHRSP x BN Map2021.46RGD
FHH x ACI Map2012.4798RGD
Cytogenetic Map20p11-q11UniSTS
D20Rat68  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82023,681,384 - 23,681,613 (+)Marker Load Pipeline
mRatBN7.22023,682,687 - 23,682,918 (+)MAPPERmRatBN7.2
Rnor_6.02025,130,768 - 25,130,996NCBIRnor6.0
Rnor_5.02027,199,085 - 27,199,313UniSTSRnor5.0
RGSC_v3.42024,696,455 - 24,696,683RGDRGSC3.4
RGSC_v3.42024,696,455 - 24,696,683UniSTSRGSC3.4
Celera2025,018,877 - 25,019,105UniSTS
RGSC_v3.12024,710,255 - 24,710,644RGD
FHH x ACI Map2012.4099RGD
FHH x ACI Map2012.4099UniSTS
Cytogenetic Map20p11-q11UniSTS
D20Got110  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82024,975,115 - 24,975,235 (+)Marker Load Pipeline
mRatBN7.22024,976,452 - 24,976,574 (+)MAPPERmRatBN7.2
Rnor_6.02026,460,883 - 26,461,002NCBIRnor6.0
Rnor_5.02028,523,846 - 28,523,965UniSTSRnor5.0
RGSC_v3.42026,048,678 - 26,048,797UniSTSRGSC3.4
Celera2026,285,507 - 26,285,626UniSTS
Cytogenetic Map20p11-q11UniSTS
D20Got120  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,107,324 - 24,107,542 (+)MAPPERmRatBN7.2
Rnor_6.02025,576,793 - 25,577,010NCBIRnor6.0
Rnor_5.02027,644,418 - 27,644,635UniSTSRnor5.0
RGSC_v3.42026,932,614 - 26,932,831UniSTSRGSC3.4
Celera2025,440,192 - 25,440,409UniSTS
Cytogenetic Map20p11-q11UniSTS
D20Got115  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82024,823,491 - 24,823,733 (+)Marker Load Pipeline
mRatBN7.22024,824,834 - 24,825,076 (+)MAPPERmRatBN7.2
Rnor_6.02026,305,642 - 26,305,883NCBIRnor6.0
Rnor_5.02028,370,631 - 28,370,872UniSTSRnor5.0
RGSC_v3.42026,207,147 - 26,207,388UniSTSRGSC3.4
Celera2026,143,431 - 26,143,674UniSTS
Cytogenetic Map20p11-q11UniSTS
D20Got106  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,718,246 - 24,718,453 (+)MAPPERmRatBN7.2
Rnor_6.02026,192,405 - 26,192,609NCBIRnor6.0
Rnor_5.02028,262,782 - 28,262,986UniSTSRnor5.0
RGSC_v3.42026,315,542 - 26,315,746UniSTSRGSC3.4
Celera2026,040,904 - 26,041,108UniSTS
Cytogenetic Map20p11-q11UniSTS
D20Got127  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,901,881 - 24,902,007 (+)MAPPERmRatBN7.2
Rnor_6.02026,382,428 - 26,382,553NCBIRnor6.0
Rnor_5.02028,447,258 - 28,447,383UniSTSRnor5.0
RGSC_v3.42026,129,094 - 26,129,219UniSTSRGSC3.4
Celera2026,220,910 - 26,221,035UniSTS
Cytogenetic Map20p11-q11UniSTS
AU048277  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02025,825,996 - 25,826,074NCBIRnor6.0
Rnor_6.02025,825,996 - 25,826,100NCBIRnor6.0
Rnor_5.02027,896,042 - 27,896,146UniSTSRnor5.0
Rnor_5.02027,896,042 - 27,896,120UniSTSRnor5.0
RGSC_v3.42026,689,175 - 26,689,279UniSTSRGSC3.4
RGSC_v3.42026,689,201 - 26,689,279UniSTSRGSC3.4
Celera2025,681,867 - 25,681,945UniSTS
Celera2025,681,867 - 25,681,971UniSTS
Cytogenetic Map20p11-q11UniSTS
RH138113  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22023,623,750 - 23,623,910 (+)MAPPERmRatBN7.2
Rnor_6.02025,064,630 - 25,064,789NCBIRnor6.0
Rnor_5.02027,132,947 - 27,133,106UniSTSRnor5.0
RGSC_v3.42024,636,284 - 24,636,443UniSTSRGSC3.4
Celera2024,959,852 - 24,960,011UniSTS
Cytogenetic Map20p11-q11UniSTS
RH130615  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22025,053,750 - 25,053,967 (-)MAPPERmRatBN7.2
mRatBN7.22025,053,750 - 25,053,967 (+)MAPPERmRatBN7.2
mRatBN7.22196,192,321 - 196,192,538 (-)MAPPERmRatBN7.2
mRatBN7.22196,192,321 - 196,192,538 (+)MAPPERmRatBN7.2
Rnor_6.02211,346,729 - 211,346,945NCBIRnor6.0
Rnor_6.02026,536,809 - 26,537,025NCBIRnor6.0
Rnor_5.02230,816,524 - 230,816,740UniSTSRnor5.0
Rnor_5.02028,600,185 - 28,600,401UniSTSRnor5.0
RGSC_v3.42204,123,731 - 204,123,947UniSTSRGSC3.4
RGSC_v3.42025,957,978 - 25,958,194UniSTSRGSC3.4
Celera2026,355,641 - 26,355,857UniSTS
Celera2188,838,212 - 188,838,428UniSTS
RH 3.4 Map17356.3UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map20p11-q11UniSTS
RH144032  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,690,125 - 24,690,236 (+)MAPPERmRatBN7.2
Rnor_6.02026,164,113 - 26,164,223NCBIRnor6.0
Rnor_5.02028,234,258 - 28,234,368UniSTSRnor5.0
RGSC_v3.42026,343,330 - 26,343,440UniSTSRGSC3.4
Celera2026,013,623 - 26,013,733UniSTS
Cytogenetic Map20p11-q11UniSTS
AU047967  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22025,039,866 - 25,040,155 (+)MAPPERmRatBN7.2
Rnor_6.02026,522,625 - 26,522,913NCBIRnor6.0
Rnor_5.02028,586,001 - 28,586,289UniSTSRnor5.0
RGSC_v3.42025,972,443 - 25,972,731UniSTSRGSC3.4
Celera2026,340,187 - 26,340,453UniSTS
Cytogenetic Map20p11-q11UniSTS
RH139003  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22196,193,218 - 196,193,345 (+)MAPPERmRatBN7.2
mRatBN7.22025,052,943 - 25,053,070 (-)MAPPERmRatBN7.2
mRatBN7.22025,052,943 - 25,053,070 (+)MAPPERmRatBN7.2
mRatBN7.22196,193,218 - 196,193,345 (-)MAPPERmRatBN7.2
Rnor_6.02211,347,626 - 211,347,752NCBIRnor6.0
Rnor_6.02026,536,002 - 26,536,128NCBIRnor6.0
Rnor_5.02230,817,421 - 230,817,547UniSTSRnor5.0
Rnor_5.02028,599,378 - 28,599,504UniSTSRnor5.0
RGSC_v3.42025,958,875 - 25,959,001UniSTSRGSC3.4
RGSC_v3.42204,124,628 - 204,124,754UniSTSRGSC3.4
Celera2026,354,834 - 26,354,960UniSTS
RH 3.4 Map21395.3UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map20p11-q11UniSTS
RH140435  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,693,124 - 24,693,255 (+)MAPPERmRatBN7.2
Rnor_6.02026,167,112 - 26,167,242NCBIRnor6.0
Rnor_5.02028,237,257 - 28,237,387UniSTSRnor5.0
RGSC_v3.42026,340,311 - 26,340,441UniSTSRGSC3.4
Celera2026,016,622 - 26,016,752UniSTS
Cytogenetic Map20p11-q11UniSTS
AI013181  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22196,193,979 - 196,194,127 (-)MAPPERmRatBN7.2
mRatBN7.22196,193,979 - 196,194,127 (+)MAPPERmRatBN7.2
mRatBN7.22025,052,161 - 25,052,309 (-)MAPPERmRatBN7.2
mRatBN7.22025,052,161 - 25,052,309 (+)MAPPERmRatBN7.2
Rnor_6.02026,535,220 - 26,535,367NCBIRnor6.0
Rnor_6.02211,348,387 - 211,348,534NCBIRnor6.0
Rnor_5.02230,818,182 - 230,818,329UniSTSRnor5.0
Rnor_5.02028,598,596 - 28,598,743UniSTSRnor5.0
RGSC_v3.42204,125,389 - 204,125,536UniSTSRGSC3.4
RGSC_v3.42025,959,636 - 25,959,783UniSTSRGSC3.4
Celera2026,354,052 - 26,354,199UniSTS
Celera2188,839,452 - 188,839,599UniSTS
RH 3.4 Map21395.8UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map20p11-q11UniSTS
BM390539  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22196,194,358 - 196,194,518 (-)MAPPERmRatBN7.2
mRatBN7.22196,194,358 - 196,194,518 (+)MAPPERmRatBN7.2
mRatBN7.22025,051,770 - 25,051,930 (-)MAPPERmRatBN7.2
mRatBN7.22025,051,770 - 25,051,930 (+)MAPPERmRatBN7.2
Rnor_6.02026,534,829 - 26,534,988NCBIRnor6.0
Rnor_6.02211,348,766 - 211,348,925NCBIRnor6.0
Rnor_5.02230,818,561 - 230,818,720UniSTSRnor5.0
Rnor_5.02028,598,205 - 28,598,364UniSTSRnor5.0
RGSC_v3.42204,125,768 - 204,125,927UniSTSRGSC3.4
RGSC_v3.42025,960,015 - 25,960,174UniSTSRGSC3.4
Celera2026,353,661 - 26,353,820UniSTS
Celera2188,839,831 - 188,839,990UniSTS
RH 3.4 Map21409.0UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map20p11-q11UniSTS
AU049904  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,556,622 - 24,556,810 (+)MAPPERmRatBN7.2
Rnor_6.02026,031,411 - 26,031,598NCBIRnor6.0
Rnor_5.02028,101,556 - 28,101,743UniSTSRnor5.0
RGSC_v3.42026,477,670 - 26,477,857UniSTSRGSC3.4
Celera2025,881,098 - 25,881,285UniSTS
Cytogenetic Map20p11-q11UniSTS
Cytogenetic Map20p11UniSTS
UniSTS:485602  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22024,385,485 - 24,385,544 (+)MAPPERmRatBN7.2
mRatBN7.2354,309,254 - 54,309,840 (+)MAPPERmRatBN7.2
Rnor_6.0355,785,073 - 55,785,657NCBIRnor6.0
Rnor_6.02025,862,227 - 25,862,285NCBIRnor6.0
Rnor_5.0362,397,014 - 62,397,599UniSTSRnor5.0
Rnor_5.02027,932,273 - 27,932,331UniSTSRnor5.0
RGSC_v3.4351,686,764 - 51,687,349UniSTSRGSC3.4
Celera353,870,165 - 53,870,750UniSTS
Celera2025,718,227 - 25,718,285UniSTS
Cytogenetic Map20p11-q11UniSTS
Cytogenetic Map3q21UniSTS
RH124829  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera2025,487,230 - 25,487,363UniSTS
Celera168,091,643 - 68,091,781UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map20p11-q11UniSTS
Cytogenetic Map1q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 12 67 155 91 90 59 35 59 6 292 135 11 134 81 92 31 13 13

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001426985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010060727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC166848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000049437   ⟹   ENSRNOP00000047382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2025,032,740 - 25,107,107 (-)Ensembl
mRatBN7.2 Ensembl2025,034,080 - 25,108,461 (-)Ensembl
Rnor_6.0 Ensembl2026,516,836 - 26,589,209 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000057950   ⟹   ENSRNOP00000054759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2023,623,560 - 24,805,292 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084660   ⟹   ENSRNOP00000070169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2023,613,016 - 25,198,805 (-)Ensembl
mRatBN7.2 Ensembl2023,623,560 - 25,199,978 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099024   ⟹   ENSRNOP00000078455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2023,613,016 - 25,107,107 (-)Ensembl
mRatBN7.2 Ensembl2023,623,560 - 25,159,891 (-)Ensembl
RefSeq Acc Id: NM_001426985   ⟹   NP_001413914
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82023,613,016 - 25,137,998 (-)NCBI
RefSeq Acc Id: XM_008772942   ⟹   XP_008771164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82023,620,942 - 24,437,790 (-)NCBI
mRatBN7.22023,614,469 - 24,439,115 (-)NCBI
Rnor_6.02025,120,535 - 25,916,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772944   ⟹   XP_008771166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82023,620,942 - 25,158,546 (-)NCBI
mRatBN7.22023,623,820 - 25,159,895 (-)NCBI
Rnor_6.02025,120,535 - 26,640,428 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601852   ⟹   XP_017457341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82023,620,942 - 24,804,372 (-)NCBI
mRatBN7.22023,623,820 - 24,805,730 (-)NCBI
Rnor_6.02025,120,535 - 26,286,540 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099277   ⟹   XP_038955205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82023,620,942 - 25,198,688 (-)NCBI
mRatBN7.22023,614,469 - 25,200,018 (-)NCBI
RefSeq Acc Id: XM_039099279   ⟹   XP_038955207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82023,620,942 - 24,786,805 (-)NCBI
mRatBN7.22023,623,820 - 24,788,003 (-)NCBI
RefSeq Acc Id: XM_039099280   ⟹   XP_038955208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82024,257,251 - 25,198,697 (-)NCBI
mRatBN7.22024,258,528 - 25,200,026 (-)NCBI
RefSeq Acc Id: XM_063279290   ⟹   XP_063135360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82024,691,027 - 25,198,699 (-)NCBI
RefSeq Acc Id: XM_063279291   ⟹   XP_063135361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82024,704,684 - 25,198,698 (-)NCBI
RefSeq Acc Id: XM_063279292   ⟹   XP_063135362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82024,437,717 - 25,198,698 (-)NCBI
RefSeq Acc Id: XM_063279293   ⟹   XP_063135363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82024,704,684 - 25,138,053 (-)NCBI
RefSeq Acc Id: XR_010060727
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82024,348,306 - 25,198,698 (-)NCBI
RefSeq Acc Id: XP_008771166   ⟸   XM_008772944
- Peptide Label: isoform X2
- UniProtKB: A6JKY1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457341   ⟸   XM_017601852
- Peptide Label: isoform X3
- UniProtKB: F1M4I1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771164   ⟸   XM_008772942
- Peptide Label: isoform X5
- Sequence:
Ensembl Acc Id: ENSRNOP00000047382   ⟸   ENSRNOT00000049437
RefSeq Acc Id: XP_038955205   ⟸   XM_039099277
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JX81 (UniProtKB/TrEMBL),   A6JKY1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955207   ⟸   XM_039099279
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZKV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955208   ⟸   XM_039099280
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000070169   ⟸   ENSRNOT00000084660
Ensembl Acc Id: ENSRNOP00000078455   ⟸   ENSRNOT00000099024
Ensembl Acc Id: ENSRNOP00000054759   ⟸   ENSRNOT00000057950
RefSeq Acc Id: NP_001413914   ⟸   NM_001426985
- UniProtKB: A6JKY1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135362   ⟸   XM_063279292
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063135360   ⟸   XM_063279290
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063135361   ⟸   XM_063279291
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063135363   ⟸   XM_063279293
- Peptide Label: isoform X10

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RYN9-F1-model_v2 AlphaFold B2RYN9 1-154 view protein structure
AF-F1M4I1-F1-model_v2 AlphaFold F1M4I1 1-545 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562230 AgrOrtholog
BioCyc Gene G2FUF-3829 BioCyc
Ensembl Genes ENSRNOG00000000373 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000000378 Ensembl
Ensembl Transcript ENSRNOT00000049437.5 UniProtKB/TrEMBL
  ENSRNOT00000084660 ENTREZGENE
  ENSRNOT00000084660.3 UniProtKB/TrEMBL
  ENSRNOT00000099024 ENTREZGENE
  ENSRNOT00000099024.2 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.2510 UniProtKB/TrEMBL
  Alpha-catenin/vinculin-like UniProtKB/TrEMBL
  Vinculin, Vh2 four-helix bundle UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9035703 IMAGE-MGC_LOAD
InterPro Alpha-catenin/vinculin-like_sf UniProtKB/TrEMBL
  Alpha_catenin UniProtKB/TrEMBL
  Vinculin/catenin UniProtKB/TrEMBL
MGC_CLONE MGC:188744 IMAGE-MGC_LOAD
NCBI Gene 361839 ENTREZGENE
PANTHER ALPHA CATENIN UniProtKB/TrEMBL
  CATENIN ALPHA-3 UniProtKB/TrEMBL
Pfam Vinculin UniProtKB/TrEMBL
PhenoGen Ctnna3 PhenoGen
PRINTS ALPHACATENIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000373 RatGTEx
  ENSRNOG00000000378 RatGTEx
Superfamily-SCOP SSF47220 UniProtKB/TrEMBL
UniProt A0A0G2JX81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKV7 ENTREZGENE, UniProtKB/TrEMBL
  A6JKY1 ENTREZGENE, UniProtKB/TrEMBL
  B2RYN9_RAT UniProtKB/TrEMBL
  F1M4I1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Ctnna3  catenin alpha 3  AABR07044900.1    Data merged from RGD:15003207 737654 PROVISIONAL
2019-11-08 AABR07044900.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2015-11-25 Ctnna3  catenin alpha 3  Ctnna3  catenin (cadherin associated protein), alpha 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Ctnna3  catenin (cadherin associated protein), alpha 3  LOC100362857  rCG61001-like  Data merged from RGD:2323922 1643240 APPROVED
2010-05-06 LOC100362857  rCG61001-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1562230  similar to catenin alpha 3   RGD1562230_predicted  similar to catenin alpha 3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562230_predicted  similar to catenin alpha 3 (predicted)  LOC361839  similar to catenin alpha 3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC361839  similar to catenin alpha 3      Symbol and Name status set to provisional 70820 PROVISIONAL