Dtx2 (deltex E3 ubiquitin ligase 2) - Rat Genome Database

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Gene: Dtx2 (deltex E3 ubiquitin ligase 2) Rattus norvegicus
Analyze
Symbol: Dtx2
Name: deltex E3 ubiquitin ligase 2
RGD ID: 1561790
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Notch signaling pathway and protein ubiquitination. Predicted to be located in cytoplasm and nuclear membrane. Predicted to be active in nucleoplasm. Orthologous to human DTX2 (deltex E3 ubiquitin ligase 2); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: deltex 2 homolog; deltex 2 homolog (Drosophila); deltex 2, E3 ubiquitin ligase; deltex homolog 2; deltex homolog 2 (Drosophila); probable E3 ubiquitin-protein ligase DTX2; protein deltex-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Dtx2-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,279,899 - 26,319,541 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,279,899 - 26,319,507 (-)EnsemblGRCr8
mRatBN7.21220,643,289 - 20,682,908 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1220,643,297 - 20,682,885 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1221,783,985 - 21,823,397 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,396,696 - 22,436,108 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,461,240 - 21,500,895 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01223,687,958 - 23,727,594 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1223,687,966 - 23,727,564 (-)Ensemblrn6Rnor6.0
Rnor_5.01225,686,606 - 25,726,242 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41221,758,490 - 21,798,085 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,406,726 - 22,446,210 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA,ISO)
nuclear membrane  (IEA,ISO)
nucleoplasm  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11226752   PMID:12477932  


Genomics

Comparative Map Data
Dtx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,279,899 - 26,319,541 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,279,899 - 26,319,507 (-)EnsemblGRCr8
mRatBN7.21220,643,289 - 20,682,908 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1220,643,297 - 20,682,885 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1221,783,985 - 21,823,397 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,396,696 - 22,436,108 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,461,240 - 21,500,895 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01223,687,958 - 23,727,594 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1223,687,966 - 23,727,564 (-)Ensemblrn6Rnor6.0
Rnor_5.01225,686,606 - 25,726,242 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41221,758,490 - 21,798,085 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,406,726 - 22,446,210 (-)NCBICelera
Cytogenetic Map12q12NCBI
DTX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38776,461,709 - 76,505,991 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl776,461,656 - 76,506,471 (+)Ensemblhg38GRCh38
GRCh37776,091,026 - 76,135,308 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,928,908 - 75,973,248 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34775,735,668 - 75,779,956NCBI
Celera771,136,116 - 71,144,477 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef771,176,386 - 71,179,184 (+)NCBIHuRef
HuRef771,180,139 - 71,182,711 (+)NCBIHuRef
CHM1_1776,021,329 - 76,065,670 (+)NCBICHM1_1
T2T-CHM13v2.0777,750,196 - 77,797,419 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2775,424,036 - 75,468,376 (+)NCBI
Dtx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395136,023,654 - 136,061,735 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5136,023,654 - 136,061,726 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385135,994,800 - 136,032,881 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,994,800 - 136,032,872 (+)Ensemblmm10GRCm38
MGSCv375136,470,747 - 136,508,734 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365136,279,504 - 136,317,491 (+)NCBIMGSCv36mm8
Celera5133,013,084 - 133,052,244 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.64NCBI
Dtx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545615,034,189 - 15,074,193 (+)Ensembl
ChiLan1.0NW_00495545615,034,214 - 15,070,521 (+)NCBIChiLan1.0ChiLan1.0
DTX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2693,442,252 - 93,491,024 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17141,706,860 - 141,755,687 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0767,509,102 - 67,537,030 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
DTX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.167,605,496 - 7,644,215 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl67,605,876 - 7,644,219 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha69,300,752 - 9,339,286 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.067,425,749 - 7,464,283 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl67,426,127 - 7,464,276 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.167,394,667 - 7,433,164 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.067,357,589 - 7,396,258 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.067,520,856 - 7,559,558 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dtx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344132,039,081 - 132,069,610 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365431,966,774 - 1,997,097 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365431,966,916 - 1,997,440 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DTX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl39,888,561 - 9,925,850 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.139,880,586 - 9,925,866 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.239,781,021 - 9,801,874 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DTX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12810,596,698 - 10,641,118 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2810,596,740 - 10,641,226 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660705,772,217 - 5,819,903 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dtx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474015,055,915 - 15,098,322 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474015,055,984 - 15,098,322 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dtx2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11617,982,040 - 18,021,633 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dtx2
485 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:65
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000001950
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)122013902826430640Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat

Markers in Region
AU022494  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X139,680,514 - 139,680,732 (+)MAPPERmRatBN7.2
mRatBN7.21220,643,310 - 20,643,528 (-)MAPPERmRatBN7.2
Rnor_6.0X144,418,927 - 144,419,144NCBIRnor6.0
Rnor_5.0X144,444,138 - 144,444,355UniSTSRnor5.0
RGSC_v3.4X146,898,383 - 146,898,600UniSTSRGSC3.4
CeleraX135,724,984 - 135,725,201UniSTS
Cytogenetic MapXq36UniSTS
Cytogenetic Map12q12UniSTS
RH130322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X139,680,528 - 139,680,717 (+)MAPPERmRatBN7.2
mRatBN7.21220,643,325 - 20,643,514 (-)MAPPERmRatBN7.2
mRatBN7.21220,643,325 - 20,643,514 (+)MAPPERmRatBN7.2
mRatBN7.2X139,680,528 - 139,680,717 (-)MAPPERmRatBN7.2
Rnor_6.0X144,418,941 - 144,419,129NCBIRnor6.0
Rnor_6.01223,687,995 - 23,688,183NCBIRnor6.0
Rnor_5.0X144,444,152 - 144,444,340UniSTSRnor5.0
Rnor_5.01225,686,643 - 25,686,831UniSTSRnor5.0
RGSC_v3.4X146,898,397 - 146,898,585UniSTSRGSC3.4
RGSC_v3.41221,758,519 - 21,758,707UniSTSRGSC3.4
Celera1222,406,755 - 22,406,943UniSTS
CeleraX135,724,998 - 135,725,186UniSTS
Cytogenetic MapXq36UniSTS
Cytogenetic Map12q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001950   ⟹   ENSRNOP00000001950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,279,899 - 26,319,507 (-)Ensembl
mRatBN7.2 Ensembl1220,643,297 - 20,682,885 (-)Ensembl
Rnor_6.0 Ensembl1223,687,966 - 23,727,564 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085911   ⟹   ENSRNOP00000071292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,280,500 - 26,319,507 (-)Ensembl
mRatBN7.2 Ensembl1220,643,349 - 20,682,817 (-)Ensembl
Rnor_6.0 Ensembl1223,687,966 - 23,727,535 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110093   ⟹   ENSRNOP00000080750
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,279,903 - 26,317,992 (-)Ensembl
mRatBN7.2 Ensembl1220,643,297 - 20,681,375 (-)Ensembl
RefSeq Acc Id: NM_001107157   ⟹   NP_001100627
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,279,899 - 26,319,507 (-)NCBI
mRatBN7.21220,643,293 - 20,682,892 (-)NCBI
Rnor_6.01223,687,966 - 23,727,564 (-)NCBI
Rnor_5.01225,686,606 - 25,726,242 (-)NCBI
RGSC_v3.41221,758,490 - 21,798,085 (-)RGD
Celera1222,406,726 - 22,446,210 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249159   ⟹   XP_006249221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,279,899 - 26,319,541 (-)NCBI
mRatBN7.21220,643,289 - 20,682,908 (-)NCBI
Rnor_6.01223,687,958 - 23,727,593 (-)NCBI
Rnor_5.01225,686,606 - 25,726,242 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089526   ⟹   XP_038945454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,279,899 - 26,319,526 (-)NCBI
mRatBN7.21220,643,289 - 20,682,908 (-)NCBI
RefSeq Acc Id: NP_001100627   ⟸   NM_001107157
- UniProtKB: G3V658 (UniProtKB/TrEMBL),   A6J094 (UniProtKB/TrEMBL),   B2RYD5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249221   ⟸   XM_006249159
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZTQ2 (UniProtKB/TrEMBL),   A6J092 (UniProtKB/TrEMBL),   B2RYD5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071292   ⟸   ENSRNOT00000085911
Ensembl Acc Id: ENSRNOP00000001950   ⟸   ENSRNOT00000001950
RefSeq Acc Id: XP_038945454   ⟸   XM_039089526
- Peptide Label: isoform X1
- UniProtKB: G3V658 (UniProtKB/TrEMBL),   A6J094 (UniProtKB/TrEMBL),   B2RYD5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000080750   ⟸   ENSRNOT00000110093
Protein Domains
RING-type   WWE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V658-F1-model_v2 AlphaFold G3V658 1-619 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698543
Promoter ID:EPDNEW_R9067
Type:multiple initiation site
Name:Dtx2_1
Description:deltex E3 ubiquitin ligase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01223,727,549 - 23,727,609EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561790 AgrOrtholog
BioCyc Gene G2FUF-19646 BioCyc
Ensembl Genes ENSRNOG00000001432 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001950 ENTREZGENE
  ENSRNOT00000001950.8 UniProtKB/TrEMBL
  ENSRNOT00000085911.3 UniProtKB/TrEMBL
  ENSRNOT00000110093 ENTREZGENE
  ENSRNOT00000110093.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.390.130 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  3.30.720.50 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7937292 IMAGE-MGC_LOAD
InterPro Deltex_C UniProtKB/TrEMBL
  Deltex_C_sf UniProtKB/TrEMBL
  Deltex_fam UniProtKB/TrEMBL
  WWE-dom UniProtKB/TrEMBL
  WWE-dom_subgr UniProtKB/TrEMBL
  WWE_dom_sf UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:304591 UniProtKB/TrEMBL
MGC_CLONE MGC:188465 IMAGE-MGC_LOAD
NCBI Gene 304591 ENTREZGENE
PANTHER PTHR12622 UniProtKB/TrEMBL
Pfam DTC UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PhenoGen Dtx2 PhenoGen
PROSITE WWE UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001432 RatGTEx
SMART RING UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF117839 UniProtKB/TrEMBL
UniProt A0A0G2K039_RAT UniProtKB/TrEMBL
  A0A8I5ZTQ2 ENTREZGENE, UniProtKB/TrEMBL
  A6J092 ENTREZGENE, UniProtKB/TrEMBL
  A6J094 ENTREZGENE, UniProtKB/TrEMBL
  B2RYD5 ENTREZGENE, UniProtKB/TrEMBL
  G3V658 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-22 Dtx2  deltex E3 ubiquitin ligase 2  Dtx2  deltex 2, E3 ubiquitin ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-02-06 Dtx2  deltex 2, E3 ubiquitin ligase  Dtx2  deltex homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Dtx2  deltex homolog 2 (Drosophila)  Dtx2  deltex 2 homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Dtx2  deltex 2 homolog (Drosophila)      Symbol and Name status set to provisional 70820 PROVISIONAL