Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Git2 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of GIT2 mRNA | CTD | PMID:22079256 | Git2 | Rat | (2,4,5-trichlorophenoxy)acetic acid | decreases expression | ISO | Git2 (Mus musculus) | 6480464 | 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GIT2 mRNA | CTD | PMID:18579281 | Git2 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Git2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of GIT2 mRNA | CTD | PMID:22206623 | Git2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Git2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of GIT2 mRNA | CTD | PMID:17555576|PMID:17942748 | Git2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Git2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GIT2 promoter] | CTD | PMID:19654925 | Git2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Git2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GIT2 mRNA | CTD | PMID:21570461 | Git2 | Rat | 2,4,6-trinitrotoluene | affects expression | EXP | | 6480464 | Trinitrotoluene affects the expression of GIT2 mRNA | CTD | PMID:21346803 | Git2 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of GIT2 mRNA | CTD | PMID:21346803 | Git2 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of GIT2 mRNA | CTD | PMID:30851411 | Git2 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Git2 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GIT2 mRNA | CTD | PMID:20188158 | Git2 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Git2 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of GIT2 exon | CTD | PMID:33297965 | Git2 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Git2 (Mus musculus) | 6480464 | bisphenol S affects the methylation of GIT2 gene | CTD | PMID:31683443 | Git2 | Rat | 5-aza-2'-deoxycytidine | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | Decitabine inhibits the reaction [Smoke results in decreased expression of GIT2 mRNA] | CTD | PMID:21095227 | Git2 | Rat | aflatoxin B1 | increases expression | ISO | Git2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of GIT2 mRNA | CTD | PMID:19770486 | Git2 | Rat | all-trans-retinoic acid | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of GIT2 mRNA | CTD | PMID:33167477 | Git2 | Rat | arsenous acid | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of GIT2 mRNA | CTD | PMID:15761015 | Git2 | Rat | atrazine | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Atrazine results in increased expression of GIT2 mRNA | CTD | PMID:22378314 | Git2 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of GIT2 gene | CTD | PMID:28931070 | Git2 | Rat | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Git2 | Rat | benzo[a]pyrene | increases expression | ISO | Git2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of GIT2 mRNA | CTD | PMID:22228805 | Git2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GIT2 mRNA | CTD | PMID:19150397 | Git2 | Rat | beta-lapachone | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of GIT2 mRNA | CTD | PMID:38218311 | Git2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GIT2 mRNA | CTD | PMID:25181051 | Git2 | Rat | bisphenol A | decreases methylation | ISO | GIT2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of GIT2 gene | CTD | PMID:31601247 | Git2 | Rat | bisphenol A | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GIT2 gene | CTD | PMID:31601247 | Git2 | Rat | bisphenol A | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GIT2 protein | CTD | PMID:33376534 | Git2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GIT2 mRNA | CTD | PMID:34947998|PMID:35192832 | Git2 | Rat | bisphenol A | decreases methylation | ISO | Git2 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of GIT2 promoter | CTD | PMID:27312807 | Git2 | Rat | bisphenol AF | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of GIT2 protein | CTD | PMID:34186270 | Git2 | Rat | cadmium atom | multiple interactions | ISO | Git2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GIT2 more ... | CTD | PMID:37236586 | Git2 | Rat | cadmium dichloride | multiple interactions | ISO | Git2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GIT2 more ... | CTD | PMID:37236586 | Git2 | Rat | caffeine | increases phosphorylation | ISO | GIT2 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of GIT2 protein | CTD | PMID:35688186 | Git2 | Rat | camptothecin | decreases response to substance | ISO | GIT2 (Homo sapiens) | 6480464 | GIT2 mRNA results in decreased susceptibility to Camptothecin | CTD | PMID:25269479 | Git2 | Rat | carbamazepine | affects expression | ISO | GIT2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of GIT2 mRNA | CTD | PMID:24752500 | Git2 | Rat | CGP 52608 | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GIT2 gene] | CTD | PMID:28238834 | Git2 | Rat | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Git2 | Rat | chlorpyrifos | increases expression | ISO | Git2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of GIT2 mRNA | CTD | PMID:37019170 | Git2 | Rat | coumarin | decreases phosphorylation | ISO | GIT2 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of GIT2 protein | CTD | PMID:35688186 | Git2 | Rat | diarsenic trioxide | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of GIT2 mRNA | CTD | PMID:15761015 | Git2 | Rat | Dibutyl phosphate | affects expression | ISO | GIT2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of GIT2 mRNA | CTD | PMID:37042841 | Git2 | Rat | diclofenac | affects expression | ISO | GIT2 (Homo sapiens) | 6480464 | Diclofenac affects the expression of GIT2 mRNA | CTD | PMID:24752500 | Git2 | Rat | dorsomorphin | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Git2 | Rat | ethyl methanesulfonate | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of GIT2 mRNA | CTD | PMID:23649840 | Git2 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of GIT2 mRNA | CTD | PMID:30307764 | Git2 | Rat | formaldehyde | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of GIT2 mRNA | CTD | PMID:23649840 | Git2 | Rat | formaldehyde | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of GIT2 mRNA | CTD | PMID:27905399 | Git2 | Rat | FR900359 | affects phosphorylation | ISO | GIT2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of GIT2 protein | CTD | PMID:37730182 | Git2 | Rat | fulvestrant | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GIT2 gene | CTD | PMID:31601247 | Git2 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of GIT2 gene | CTD | PMID:22079235 | Git2 | Rat | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Git2 | Rat | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Git2 | Rat | lead(0) | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Lead results in increased expression of GIT2 mRNA | CTD | PMID:19921347 | Git2 | Rat | methyl methanesulfonate | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of GIT2 mRNA | CTD | PMID:23649840 | Git2 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Git2 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with CGA protein] results in increased expression of GIT2 protein | CTD | PMID:20463053 | Git2 | Rat | nitrates | multiple interactions | ISO | Git2 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of GIT2 more ... | CTD | PMID:35964746 | Git2 | Rat | ozone | multiple interactions | ISO | Git2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Git2 | Rat | paracetamol | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of GIT2 mRNA | CTD | PMID:21420995 | Git2 | Rat | phenylmercury acetate | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of GIT2 mRNA | CTD | PMID:26272509 | Git2 | Rat | phenylmercury acetate | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Git2 | Rat | pirinixic acid | multiple interactions | ISO | Git2 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Git2 | Rat | potassium chromate | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of GIT2 mRNA | CTD | PMID:22079256 | Git2 | Rat | potassium chromate | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of GIT2 mRNA | CTD | PMID:22079256 | Git2 | Rat | rac-lactic acid | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of GIT2 mRNA | CTD | PMID:30851411 | Git2 | Rat | resveratrol | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | resveratrol results in decreased expression of GIT2 protein | CTD | PMID:18089832 | Git2 | Rat | SB 431542 | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Git2 | Rat | sodium arsenate | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | sodium arsenate results in increased expression of GIT2 protein | CTD | PMID:38348393 | Git2 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of GIT2 mRNA | CTD | PMID:19281266 | Git2 | Rat | tamoxifen | affects expression | ISO | Git2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of GIT2 mRNA | CTD | PMID:17555576 | Git2 | Rat | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... | CTD | PMID:33854195 | Git2 | Rat | thimerosal | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of GIT2 mRNA | CTD | PMID:27188386 | Git2 | Rat | titanium dioxide | decreases methylation | ISO | Git2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of GIT2 gene | CTD | PMID:35295148 | Git2 | Rat | torcetrapib | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of GIT2 mRNA | CTD | PMID:23228038 | Git2 | Rat | trichostatin A | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of GIT2 mRNA | CTD | PMID:24935251 | Git2 | Rat | triptonide | increases expression | ISO | Git2 (Mus musculus) | 6480464 | triptonide results in increased expression of GIT2 mRNA | CTD | PMID:33045310 | Git2 | Rat | tungsten | decreases expression | ISO | Git2 (Mus musculus) | 6480464 | Tungsten results in decreased expression of GIT2 mRNA | CTD | PMID:30912803 | Git2 | Rat | valproic acid | increases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GIT2 mRNA | CTD | PMID:19101580 | Git2 | Rat | valproic acid | affects expression | ISO | GIT2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of GIT2 mRNA | CTD | PMID:25979313 | Git2 | Rat | valproic acid | decreases expression | ISO | GIT2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of GIT2 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:24935251|PMID:25192806|PMID:26272509|PMID:28001369 | Git2 | Rat | valproic acid | multiple interactions | ISO | GIT2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||





















