Git2 (GIT ArfGAP 2) - Rat Genome Database

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Pathways
Gene: Git2 (GIT ArfGAP 2) Rattus norvegicus
Analyze
Symbol: Git2
Name: GIT ArfGAP 2
RGD ID: 1359708
Description: Predicted to enable GTPase activator activity and small GTPase binding activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; regulation of signal transduction; and synaptic vesicle recycling. Predicted to act upstream of or within behavioral response to pain. Predicted to be located in nucleoplasm. Predicted to be active in calyx of Held. Orthologous to human GIT2 (GIT ArfGAP 2); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,4,6-trinitrotoluene; 2,6-dinitrotoluene; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ARF GAP GIT2; ARF GTPase-activating protein GIT2; CAT-2; CAT2; cool-interacting tyrosine-phosphorylated protein 2; G protein-coupled receptor kinase interacting ArfGAP 2; G protein-coupled receptor kinase-interactor 2; GRK-interacting protein 2; MGC94099; similar to Git2 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,490,350 - 47,531,232 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1247,490,369 - 47,533,250 (+)EnsemblGRCr8
mRatBN7.21241,829,717 - 41,872,621 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,829,730 - 41,871,097 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1242,997,345 - 43,038,116 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,610,923 - 43,651,694 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,671,415 - 42,712,186 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,590,110 - 47,630,991 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,590,154 - 47,631,119 (+)Ensemblrn6Rnor6.0
Rnor_5.01249,383,645 - 49,424,284 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41243,117,706 - 43,158,710 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1243,445,286 - 43,486,291 (+)NCBICelera
RGSC_v3.11242,981,093 - 43,022,097 (+)NCBI
Cytogenetic Map12q16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
calyx of Held  (ISO)
distal axon  (IEA)
nucleoplasm  (IEA,ISO)
presynapse  (ISO)
synapse  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins. Bagrodia S, etal., J Biol Chem 1999 Aug 6;274(32):22393-400.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10942595   PMID:17310244   PMID:19912111   PMID:21423176   PMID:22606319   PMID:23870131   PMID:26637799   PMID:28131823  


Genomics

Comparative Map Data
Git2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,490,350 - 47,531,232 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1247,490,369 - 47,533,250 (+)EnsemblGRCr8
mRatBN7.21241,829,717 - 41,872,621 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,829,730 - 41,871,097 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1242,997,345 - 43,038,116 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,610,923 - 43,651,694 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,671,415 - 42,712,186 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,590,110 - 47,630,991 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,590,154 - 47,631,119 (+)Ensemblrn6Rnor6.0
Rnor_5.01249,383,645 - 49,424,284 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41243,117,706 - 43,158,710 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1243,445,286 - 43,486,291 (+)NCBICelera
RGSC_v3.11242,981,093 - 43,022,097 (+)NCBI
Cytogenetic Map12q16NCBI
GIT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812109,929,804 - 110,000,164 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12109,929,792 - 109,996,389 (-)Ensemblhg38GRCh38
GRCh3712110,367,609 - 110,434,173 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,851,992 - 108,918,483 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3412108,848,588 - 108,896,820NCBI
Celera12109,991,955 - 110,058,428 (-)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12107,383,692 - 107,449,937 (-)NCBIHuRef
CHM1_112110,335,391 - 110,401,989 (-)NCBICHM1_1
T2T-CHM13v2.012109,905,496 - 109,975,853 (-)NCBIT2T-CHM13v2.0
Git2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,865,469 - 114,912,647 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,865,468 - 114,913,578 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385114,727,408 - 114,774,588 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,727,407 - 114,775,517 (-)Ensemblmm10GRCm38
MGSCv375115,177,417 - 115,223,501 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365114,988,410 - 115,034,490 (-)NCBIMGSCv36mm8
Celera5111,825,622 - 111,871,698 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.99NCBI
Git2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554558,613,490 - 8,670,205 (+)Ensembl
ChiLan1.0NW_0049554558,611,218 - 8,669,527 (+)NCBIChiLan1.0ChiLan1.0
GIT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210117,996,751 - 118,063,703 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112117,993,154 - 118,060,124 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012107,505,791 - 107,572,641 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112110,901,293 - 110,967,489 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,901,303 - 110,967,489 (-)EnsemblpanPan2panpan1.1
GIT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,170,651 - 17,217,634 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,170,680 - 17,214,631 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2618,584,319 - 18,631,531 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02617,515,164 - 17,562,316 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2617,515,162 - 17,562,313 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,794,107 - 18,841,098 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02617,504,924 - 17,552,144 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02617,522,393 - 17,569,401 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Git2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118143,901,711 - 143,948,385 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367691,527,151 - 1,574,892 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367691,529,983 - 1,574,805 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GIT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,995,988 - 41,051,902 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11440,995,986 - 41,051,896 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21443,511,566 - 43,567,474 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GIT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111105,171,441 - 105,235,661 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11105,169,099 - 105,235,290 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037139,885,173 - 139,947,837 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Git2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474710,518,671 - 10,580,179 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474710,518,651 - 10,580,179 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Git2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11639,181,284 - 39,222,929 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:286
Count of miRNA genes:187
Interacting mature miRNAs:206
Transcripts:ENSRNOT00000045946
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)124413955852308831Rat

Markers in Region
RH132951  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,844,122 - 41,844,307 (+)MAPPERmRatBN7.2
Rnor_6.01247,604,513 - 47,604,697NCBIRnor6.0
Rnor_5.01249,398,038 - 49,398,222UniSTSRnor5.0
RGSC_v3.41243,132,055 - 43,132,239UniSTSRGSC3.4
Celera1243,459,635 - 43,459,819UniSTS
RH 3.4 Map12781.83UniSTS
Cytogenetic Map12q16UniSTS
BE120218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,842,950 - 41,843,127 (+)MAPPERmRatBN7.2
Rnor_6.01247,603,341 - 47,603,517NCBIRnor6.0
Rnor_5.01249,396,866 - 49,397,042UniSTSRnor5.0
RGSC_v3.41243,130,883 - 43,131,059UniSTSRGSC3.4
Celera1243,458,463 - 43,458,639UniSTS
RH 3.4 Map12779.53UniSTS
Cytogenetic Map12q16UniSTS
AI511444  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,870,248 - 41,870,453 (+)MAPPERmRatBN7.2
Rnor_6.01247,630,639 - 47,630,843NCBIRnor6.0
Rnor_5.01249,423,932 - 49,424,136UniSTSRnor5.0
RGSC_v3.41243,158,358 - 43,158,562UniSTSRGSC3.4
Celera1243,485,939 - 43,486,143UniSTS
Cytogenetic Map12q16UniSTS
RH139528  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,868,466 - 41,868,664 (+)MAPPERmRatBN7.2
Rnor_6.01247,628,857 - 47,629,054NCBIRnor6.0
Rnor_5.01249,422,150 - 49,422,347UniSTSRnor5.0
RGSC_v3.41243,156,576 - 43,156,773UniSTSRGSC3.4
Celera1243,484,157 - 43,484,354UniSTS
Cytogenetic Map12q16UniSTS
RH140364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,868,504 - 41,868,664 (+)MAPPERmRatBN7.2
Rnor_6.01247,628,895 - 47,629,054NCBIRnor6.0
Rnor_5.01249,422,188 - 49,422,347UniSTSRnor5.0
RGSC_v3.41243,156,614 - 43,156,773UniSTSRGSC3.4
Celera1243,484,195 - 43,484,354UniSTS
RH 3.4 Map12778.12UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001005553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC095845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000045946   ⟹   ENSRNOP00000048331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1247,490,371 - 47,531,231 (+)Ensembl
mRatBN7.2 Ensembl1241,829,746 - 41,870,601 (+)Ensembl
Rnor_6.0 Ensembl1247,590,154 - 47,631,119 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096072   ⟹   ENSRNOP00000086491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1247,490,369 - 47,533,250 (+)Ensembl
mRatBN7.2 Ensembl1241,829,773 - 41,870,600 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097577   ⟹   ENSRNOP00000081139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1247,490,369 - 47,533,250 (+)Ensembl
mRatBN7.2 Ensembl1241,829,730 - 41,871,097 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100352   ⟹   ENSRNOP00000093537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1247,490,369 - 47,533,250 (+)Ensembl
mRatBN7.2 Ensembl1241,829,773 - 41,870,600 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105617   ⟹   ENSRNOP00000079644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1247,493,856 - 47,531,231 (+)Ensembl
mRatBN7.2 Ensembl1241,833,224 - 41,870,600 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108942   ⟹   ENSRNOP00000080405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1247,490,372 - 47,533,250 (+)Ensembl
mRatBN7.2 Ensembl1241,829,746 - 41,870,600 (+)Ensembl
RefSeq Acc Id: NM_001005553   ⟹   NP_001005553
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,405 - 47,531,232 (+)NCBI
mRatBN7.21241,829,773 - 41,870,601 (+)NCBI
Rnor_6.01247,590,164 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
RGSC_v3.41243,117,706 - 43,158,710 (+)RGD
Celera1243,445,286 - 43,486,291 (+)RGD
Sequence:
RefSeq Acc Id: XM_006249442   ⟹   XP_006249504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,360 - 47,531,232 (+)NCBI
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,110 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249445   ⟹   XP_006249507
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,360 - 47,531,232 (+)NCBI
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249447   ⟹   XP_006249509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,350 - 47,531,232 (+)NCBI
mRatBN7.21241,829,722 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249450   ⟹   XP_006249512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,360 - 47,531,232 (+)NCBI
mRatBN7.21241,829,723 - 41,872,621 (+)NCBI
Rnor_6.01247,590,111 - 47,630,991 (+)NCBI
Rnor_5.01249,383,645 - 49,424,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063271354   ⟹   XP_063127424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,359 - 47,531,232 (+)NCBI
RefSeq Acc Id: XM_063271355   ⟹   XP_063127425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,359 - 47,531,232 (+)NCBI
RefSeq Acc Id: XM_063271356   ⟹   XP_063127426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,360 - 47,531,232 (+)NCBI
RefSeq Acc Id: XM_063271357   ⟹   XP_063127427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,360 - 47,531,232 (+)NCBI
RefSeq Acc Id: XM_063271358   ⟹   XP_063127428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,360 - 47,531,232 (+)NCBI
RefSeq Acc Id: XM_063271359   ⟹   XP_063127429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,357 - 47,531,232 (+)NCBI
RefSeq Acc Id: XM_063271360   ⟹   XP_063127430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,362 - 47,531,232 (+)NCBI
RefSeq Acc Id: XM_063271361   ⟹   XP_063127431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,490,350 - 47,531,232 (+)NCBI
RefSeq Acc Id: NP_001005553   ⟸   NM_001005553
- UniProtKB: Q66H91 (UniProtKB/TrEMBL),   A0A8L2UM41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249507   ⟸   XM_006249445
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A5F6 (UniProtKB/TrEMBL),   A0A8L2UM41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249512   ⟸   XM_006249450
- Peptide Label: isoform X11
- UniProtKB: A0A8I6G6J8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249504   ⟸   XM_006249442
- Peptide Label: isoform X1
- UniProtKB: A0A8L2UM41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249509   ⟸   XM_006249447
- Peptide Label: isoform X9
- UniProtKB: A0A8I6G6J8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048331   ⟸   ENSRNOT00000045946
Ensembl Acc Id: ENSRNOP00000081139   ⟸   ENSRNOT00000097577
Ensembl Acc Id: ENSRNOP00000086491   ⟸   ENSRNOT00000096072
Ensembl Acc Id: ENSRNOP00000080405   ⟸   ENSRNOT00000108942
Ensembl Acc Id: ENSRNOP00000079644   ⟸   ENSRNOT00000105617
Ensembl Acc Id: ENSRNOP00000093537   ⟸   ENSRNOT00000100352
RefSeq Acc Id: XP_063127431   ⟸   XM_063271361
- Peptide Label: isoform X12
- UniProtKB: A0A8I6G6J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127429   ⟸   XM_063271359
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZRU3 (UniProtKB/TrEMBL),   A0A8I6G6J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127424   ⟸   XM_063271354
- Peptide Label: isoform X2
- UniProtKB: A0A8L2UM41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127425   ⟸   XM_063271355
- Peptide Label: isoform X3
- UniProtKB: A0A8L2UM41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127427   ⟸   XM_063271357
- Peptide Label: isoform X6
- UniProtKB: A0A8I6G6J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127426   ⟸   XM_063271356
- Peptide Label: isoform X5
- UniProtKB: A0A8L2UM41 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127428   ⟸   XM_063271358
- Peptide Label: isoform X7
- UniProtKB: A0A8I6G6J8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127430   ⟸   XM_063271360
- Peptide Label: isoform X10
- UniProtKB: A0A8L2UM41 (UniProtKB/TrEMBL)
Protein Domains
Arf-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H91-F1-model_v2 AlphaFold Q66H91 1-759 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698707
Promoter ID:EPDNEW_R9232
Type:initiation region
Name:Git2_1
Description:GIT ArfGAP 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01247,590,129 - 47,590,189EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359708 AgrOrtholog
BioCyc Gene G2FUF-18959 BioCyc
Ensembl Genes ENSRNOG00000001190 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000045946 ENTREZGENE
  ENSRNOT00000097577 ENTREZGENE
  ENSRNOT00000100352 ENTREZGENE
  ENSRNOT00000108942 ENTREZGENE
Gene3D-CATH 1.10.220.150 UniProtKB/Swiss-Prot
  1.20.5.170 UniProtKB/Swiss-Prot
  1.25.40.20 UniProtKB/Swiss-Prot
  Nucleotidyltransferases domain 2 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7125406 IMAGE-MGC_LOAD
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  ARFGAP/RecO UniProtKB/Swiss-Prot
  ArfGAP_dom UniProtKB/Swiss-Prot
  ArfGAP_dom_sf UniProtKB/Swiss-Prot
  GIT-like UniProtKB/Swiss-Prot
  GIT1/2_CC UniProtKB/Swiss-Prot
  GIT1_C UniProtKB/Swiss-Prot
  GIT_SHD UniProtKB/Swiss-Prot
KEGG Report rno:304546 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94099 IMAGE-MGC_LOAD
NCBI Gene 304546 ENTREZGENE
PANTHER ARF GTPASE-ACTIVATING PROTEIN GIT2 UniProtKB/Swiss-Prot
  G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP UniProtKB/Swiss-Prot
Pfam Ank_2 UniProtKB/Swiss-Prot
  ArfGap UniProtKB/Swiss-Prot
  GIT1_C UniProtKB/Swiss-Prot
  GIT_CC UniProtKB/Swiss-Prot
  GIT_SHD UniProtKB/Swiss-Prot
PhenoGen Git2 PhenoGen
PRINTS REVINTRACTNG UniProtKB/Swiss-Prot
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot
  ARFGAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001190 RatGTEx
SMART ANK UniProtKB/Swiss-Prot
  ArfGap UniProtKB/Swiss-Prot
  GIT UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot
  SSF57863 UniProtKB/Swiss-Prot
UniProt A0A8I5ZN29_RAT UniProtKB/TrEMBL
  A0A8I5ZRU3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A5F6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALK4_RAT UniProtKB/TrEMBL
  A0A8I6G6J8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UM41 ENTREZGENE, UniProtKB/TrEMBL
  A6J1Y6_RAT UniProtKB/TrEMBL
  A6J1Y7_RAT UniProtKB/TrEMBL
  GIT2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Git2  GIT ArfGAP 2  Git2  G protein-coupled receptor kinase interacting ArfGAP 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Git2  G protein-coupled receptor kinase interacting ArfGAP 2  Git2  G protein-coupled receptor kinase-interactor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Git2  G protein-coupled receptor kinase-interactor 2  MGC94099  similar to Git2 protein  Symbol and Name updated 1299863 APPROVED
2005-07-29 MGC94099  similar to Git2 protein      Symbol and Name status set to provisional 70820 PROVISIONAL