Ift74 (intraflagellar transport 74) - Rat Genome Database

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Gene: Ift74 (intraflagellar transport 74) Rattus norvegicus
Analyze
Symbol: Ift74
Name: intraflagellar transport 74
RGD ID: 1359704
Description: Predicted to enable beta-tubulin binding activity and chromatin binding activity. Predicted to be involved in intraciliary transport involved in cilium assembly. Predicted to act upstream of or within several processes, including keratinocyte development; negative regulation of keratinocyte proliferation; and non-motile cilium assembly. Predicted to be located in centrosome and nucleus. Predicted to be part of intraciliary transport particle B. Predicted to be active in cilium. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 22; Joubert syndrome; and spermatogenic failure 58. Orthologous to human IFT74 (intraflagellar transport 74); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ccdc2; coiled-coil domain containing 2; intraflagellar transport 74 homolog; intraflagellar transport 74 homolog (Chlamydomonas); intraflagellar transport protein 74 homolog; MGC94371
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85114,576,106 - 114,679,581 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5114,593,397 - 114,679,581 (+)EnsemblGRCr8
mRatBN7.25109,460,372 - 109,563,839 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5109,474,255 - 109,563,833 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5112,052,931 - 112,142,409 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05113,778,717 - 113,868,197 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05113,840,948 - 113,930,430 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05113,579,065 - 113,682,485 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5113,592,919 - 113,682,484 (+)Ensemblrn6Rnor6.0
Rnor_5.05117,523,747 - 117,629,816 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45114,913,347 - 115,003,963 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5108,101,293 - 108,191,093 (+)NCBICelera
RGSC_v3.15114,918,572 - 115,009,188 (+)NCBI
Cytogenetic Map5q33NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. Bell SE, etal., J Cell Sci 2001 Aug;114(Pt 15):2755-73.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16705683   PMID:19253336   PMID:20545763   PMID:21703454   PMID:23810713   PMID:23990561   PMID:24596149   PMID:25443296   PMID:25807483  


Genomics

Comparative Map Data
Ift74
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85114,576,106 - 114,679,581 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5114,593,397 - 114,679,581 (+)EnsemblGRCr8
mRatBN7.25109,460,372 - 109,563,839 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5109,474,255 - 109,563,833 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5112,052,931 - 112,142,409 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05113,778,717 - 113,868,197 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05113,840,948 - 113,930,430 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05113,579,065 - 113,682,485 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5113,592,919 - 113,682,484 (+)Ensemblrn6Rnor6.0
Rnor_5.05117,523,747 - 117,629,816 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45114,913,347 - 115,003,963 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5108,101,293 - 108,191,093 (+)NCBICelera
RGSC_v3.15114,918,572 - 115,009,188 (+)NCBI
Cytogenetic Map5q33NCBI
IFT74
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38926,947,110 - 27,066,134 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl926,947,039 - 27,066,134 (+)Ensemblhg38GRCh38
GRCh37926,947,108 - 27,066,132 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36926,937,037 - 27,052,931 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34926,946,409 - 27,052,802NCBI
Celera926,875,190 - 26,991,082 (+)NCBICelera
Cytogenetic Map9p21.2NCBI
HuRef926,899,912 - 27,015,729 (+)NCBIHuRef
CHM1_1926,946,816 - 27,062,719 (+)NCBICHM1_1
T2T-CHM13v2.0926,957,713 - 27,076,715 (+)NCBIT2T-CHM13v2.0
Ift74
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39494,491,503 - 94,581,470 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl494,502,728 - 94,581,466 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38494,603,266 - 94,693,233 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl494,614,491 - 94,693,229 (+)Ensemblmm10GRCm38
MGSCv37494,281,211 - 94,359,924 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36494,146,847 - 94,185,247 (+)NCBIMGSCv36mm8
Celera493,023,677 - 93,103,044 (+)NCBICelera
Cytogenetic Map4C5NCBI
cM Map443.34NCBI
Ift74
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554727,775,981 - 7,872,423 (-)Ensembl
ChiLan1.0NW_0049554727,779,705 - 7,872,423 (-)NCBIChiLan1.0ChiLan1.0
IFT74
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21197,482,355 - 97,588,966 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1997,485,095 - 97,597,750 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0926,802,459 - 26,912,292 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1927,409,962 - 27,514,756 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl927,415,565 - 27,514,558 (+)EnsemblpanPan2panpan1.1
IFT74
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11145,159,124 - 45,242,019 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1145,161,086 - 45,242,012 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1143,834,528 - 43,919,561 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01146,103,920 - 46,188,986 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1146,105,889 - 46,188,982 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11144,761,014 - 44,845,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01144,650,812 - 44,735,508 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01145,397,519 - 45,482,097 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ift74
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947160,007,880 - 160,079,709 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366112,588,695 - 2,660,532 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366112,588,711 - 2,660,496 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFT74
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1196,086,072 - 196,173,880 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11196,084,498 - 196,173,880 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,533,803 - 218,621,870 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IFT74
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1252,983,050 - 53,103,525 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Ift74
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473631,188,987 - 31,306,815 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473631,188,963 - 31,308,872 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ift74
856 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:129
Count of miRNA genes:105
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000011336
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1298077Bp157Blood pressure QTL 157arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5114474223121056531Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)5104018576124314782Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)582032155127032155Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
RH128708  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,563,602 - 109,563,801 (+)MAPPERmRatBN7.2
Rnor_6.05113,682,249 - 113,682,447NCBIRnor6.0
Rnor_5.05117,629,580 - 117,629,778UniSTSRnor5.0
RGSC_v3.45115,003,727 - 115,003,925UniSTSRGSC3.4
Celera5108,190,857 - 108,191,055UniSTS
RH 3.4 Map5780.5UniSTS
Cytogenetic Map5q33UniSTS
AI232423  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25109,497,180 - 109,497,290 (+)MAPPERmRatBN7.2
Rnor_6.05113,615,820 - 113,615,929NCBIRnor6.0
Rnor_5.05117,565,249 - 117,565,358UniSTSRnor5.0
RGSC_v3.45114,937,310 - 114,937,419UniSTSRGSC3.4
Celera5108,124,371 - 108,124,480UniSTS
RH 3.4 Map5780.5UniSTS
Cytogenetic Map5q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011336   ⟹   ENSRNOP00000011336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5114,593,397 - 114,679,581 (+)Ensembl
mRatBN7.2 Ensembl5109,474,255 - 109,563,833 (+)Ensembl
Rnor_6.0 Ensembl5113,592,919 - 113,682,484 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099310   ⟹   ENSRNOP00000097814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5114,593,397 - 114,654,242 (+)Ensembl
mRatBN7.2 Ensembl5109,474,255 - 109,538,505 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172970   ⟹   ENSRNOP00000111300
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5114,593,397 - 114,679,581 (+)Ensembl
RefSeq Acc Id: NM_001007001   ⟹   NP_001007002
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85114,590,014 - 114,679,581 (+)NCBI
mRatBN7.25109,474,280 - 109,563,839 (+)NCBI
Rnor_6.05113,592,919 - 113,682,485 (+)NCBI
Rnor_5.05117,523,747 - 117,629,816 (+)NCBI
RGSC_v3.45114,913,347 - 115,003,963 (+)RGD
Celera5108,101,293 - 108,191,093 (+)RGD
Sequence:
RefSeq Acc Id: XM_017593367   ⟹   XP_017448856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85114,576,106 - 114,679,581 (+)NCBI
mRatBN7.25109,460,372 - 109,563,836 (+)NCBI
Rnor_6.05113,579,065 - 113,682,485 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109896   ⟹   XP_038965824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85114,596,616 - 114,679,581 (+)NCBI
mRatBN7.25109,480,882 - 109,563,836 (+)NCBI
RefSeq Acc Id: XM_063287637   ⟹   XP_063143707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85114,593,395 - 114,679,581 (+)NCBI
RefSeq Acc Id: NP_001007002   ⟸   NM_001007001
- UniProtKB: Q5XIR2 (UniProtKB/TrEMBL),   F7FIM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448856   ⟸   XM_017593367
- Peptide Label: isoform X1
- UniProtKB: Q5XIR2 (UniProtKB/TrEMBL),   F7FIM8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011336   ⟸   ENSRNOT00000011336
RefSeq Acc Id: XP_038965824   ⟸   XM_039109896
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000097814   ⟸   ENSRNOT00000099310
RefSeq Acc Id: XP_063143707   ⟸   XM_063287637
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000111300   ⟸   ENSRNOT00000172970

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIR2-F1-model_v2 AlphaFold Q5XIR2 1-600 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693841
Promoter ID:EPDNEW_R4365
Type:initiation region
Name:Ift74_1
Description:intraflagellar transport 74
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05113,592,973 - 113,593,033EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359704 AgrOrtholog
BioCyc Gene G2FUF-40706 BioCyc
Ensembl Genes ENSRNOG00000008075 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011336 ENTREZGENE
  ENSRNOT00000011336.6 UniProtKB/TrEMBL
  ENSRNOT00000099310.2 UniProtKB/TrEMBL
  ENSRNOT00000172970.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.1490 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7133514 IMAGE-MGC_LOAD
InterPro IFT74 UniProtKB/TrEMBL
KEGG Report rno:313365 UniProtKB/TrEMBL
MGC_CLONE MGC:94371 IMAGE-MGC_LOAD
NCBI Gene 313365 ENTREZGENE
PANTHER INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG UniProtKB/TrEMBL
  PTHR31432 UniProtKB/TrEMBL
PhenoGen Ift74 PhenoGen
RatGTEx ENSRNOG00000008075 RatGTEx
UniProt A0A8I6ANR2_RAT UniProtKB/TrEMBL
  A0ABK0M2L6_RAT UniProtKB/TrEMBL
  F7FIM8 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIR2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-09 Ift74  intraflagellar transport 74  Ift74  intraflagellar transport 74 homolog (Chlamydomonas)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ift74  intraflagellar transport 74 homolog (Chlamydomonas)  Ccdc2  coiled-coil domain containing 2  Symbol and Name updated 1299863 APPROVED
2005-07-29 Ccdc2  coiled-coil domain containing 2      Symbol and Name status set to provisional 70820 PROVISIONAL