Or9k2b (olfactory receptor family 9 subfamily K member 2B) - Rat Genome Database

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Gene: Or9k2b (olfactory receptor family 9 subfamily K member 2B) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or9k2b
Name: olfactory receptor family 9 subfamily K member 2B
RGD ID: 1334409
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR9K2 (olfactory receptor family 9 subfamily K member 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1071; olfactory receptor gene Olr1071; olfactory receptor Olr1071; Olr1071; ratchr7-8424998-8424057_ORF
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr877,633,029 - 7,633,970 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl77,519,060 - 7,520,019 (-)EnsemblGRCr8
mRatBN7.276,982,223 - 6,983,164 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl76,981,904 - 6,986,207 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx79,905,992 - 9,906,933 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0711,781,651 - 11,782,592 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.079,589,815 - 9,590,756 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.079,591,059 - 9,592,000 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl79,591,059 - 9,592,000 (-)Ensemblrn6Rnor6.0
Rnor_5.079,757,296 - 9,758,237 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.478,424,057 - 8,424,998 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera75,199,688 - 5,200,629 (-)NCBICelera
RGSC_v3.178,424,056 - 8,424,998 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or9k2b
13 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:14
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000011188
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 5 1 1 7 5 7 2 2 1

Sequence


Ensembl Acc Id: ENSRNOT00000011188   ⟹   ENSRNOP00000011188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl76,981,904 - 6,986,207 (-)Ensembl
Rnor_6.0 Ensembl79,591,059 - 9,592,000 (-)Ensembl
RefSeq Acc Id: NM_001000063   ⟹   NP_001000063
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr877,633,029 - 7,633,970 (-)NCBI
mRatBN7.276,982,223 - 6,983,164 (-)NCBI
Rnor_6.079,591,059 - 9,592,000 (-)NCBI
Rnor_5.079,757,296 - 9,758,237 (-)NCBI
RGSC_v3.478,424,057 - 8,424,998 (-)RGD
Celera75,199,688 - 5,200,629 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000063 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89110 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011188.2
RefSeq Acc Id: NP_001000063   ⟸   NM_001000063
- UniProtKB: D4A7L2 (UniProtKB/TrEMBL),   A6K840 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011188   ⟸   ENSRNOT00000011188
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A7L2-F1-model_v2 AlphaFold D4A7L2 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334409 AgrOrtholog
BioCyc Gene G2FUF-35081 BioCyc
Ensembl Genes ENSRNOG00000008464 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011188.4 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:288823 UniProtKB/TrEMBL
NCBI Gene 288823 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or9k2b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008464 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6K840 ENTREZGENE, UniProtKB/TrEMBL
  D4A7L2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or9k2b  olfactory receptor family 9 subfamily K member 2B  Olr1071  olfactory receptor 1071  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1071  olfactory receptor 1071   Olr1071_predicted  olfactory receptor 1071 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1071_predicted  olfactory receptor 1071 (predicted)      Symbol and Name status set to approved 70820 APPROVED