Or5bh3 (olfactory receptor family 5 subfamily BH member 3) - Rat Genome Database

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Gene: Or5bh3 (olfactory receptor family 5 subfamily BH member 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or5bh3
Name: olfactory receptor family 5 subfamily BH member 3
RGD ID: 1334384
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in plasma membrane; INTERACTS WITH bisphenol A; furan.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1767; olfactory receptor gene Olr1767; olfactory receptor Olr1767; Olr1767; ratchrX-136588662-136587739_ORF
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X134,167,584 - 134,168,507 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX134,167,584 - 134,168,513 (-)EnsemblGRCr8
mRatBN7.2X129,289,761 - 129,290,684 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX129,289,761 - 129,290,690 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX131,409,208 - 131,410,131 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X134,985,504 - 134,986,427 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X132,513,073 - 132,513,996 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X137,014,343 - 137,015,266 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX137,014,343 - 137,015,266 (-)Ensemblrn6Rnor6.0
Rnor_5.0X137,078,085 - 137,079,008 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X136,514,306 - 136,515,229 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX128,212,385 - 128,213,308 (-)NCBICelera
RGSC_v3.1X136,587,738 - 136,588,662 (-)NCBI
Cytogenetic MapXq36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)
furan  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or5bh3
47 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:155
Count of miRNA genes:130
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000040369
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X120028026141353710Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X120028026141353710Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat


Expression

RNA-SEQ Expression

endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
reproductive system
2 2 2 2 2 3

Sequence


Ensembl Acc Id: ENSRNOT00000040369   ⟹   ENSRNOP00000045878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX134,167,584 - 134,168,513 (-)Ensembl
mRatBN7.2 EnsemblX129,289,761 - 129,290,690 (-)Ensembl
Rnor_6.0 EnsemblX137,014,343 - 137,015,266 (-)Ensembl
RefSeq Acc Id: NM_001000491   ⟹   NP_001000491
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X134,167,584 - 134,168,507 (-)NCBI
mRatBN7.2X129,289,761 - 129,290,684 (-)NCBI
Rnor_6.0X137,014,343 - 137,015,266 (-)NCBI
Rnor_5.0X137,078,085 - 137,079,008 (-)NCBI
RGSC_v3.4X136,514,306 - 136,515,229 (-)RGD
CeleraX128,212,385 - 128,213,308 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000491 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM10936 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045878
  ENSRNOP00000045878.4
RefSeq Acc Id: NP_001000491   ⟸   NM_001000491
- UniProtKB: F1M6J9 (UniProtKB/TrEMBL),   A6JMS4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045878   ⟸   ENSRNOT00000040369
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M6J9-F1-model_v2 AlphaFold F1M6J9 1-307 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334384 AgrOrtholog
BioCyc Gene G2FUF-1111 BioCyc
Ensembl Genes ENSRNOG00000029322 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040369 ENTREZGENE
  ENSRNOT00000040369.5 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:302824 UniProtKB/TrEMBL
NCBI Gene 302824 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5bh3 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029322 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6JMS4 ENTREZGENE, UniProtKB/TrEMBL
  F1M6J9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or5bh3  olfactory receptor family 5 subfamily BH member 3  Olr1767  olfactory receptor 1767  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1767  olfactory receptor 1767   Olr1767_predicted  olfactory receptor 1767 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1767_predicted  olfactory receptor 1767 (predicted)      Symbol and Name status set to approved 70820 APPROVED