Or5k16 (olfactory receptor family 5 subfamily K member 16) - Rat Genome Database

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Gene: Or5k16 (olfactory receptor family 5 subfamily K member 16) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or5k16
Name: olfactory receptor family 5 subfamily K member 16
RGD ID: 1333528
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR5K4 (olfactory receptor family 5 subfamily K member 4).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC108352374; olfactory receptor 1559; olfactory receptor gene Olr1559; olfactory receptor Olfr180-like; olfactory receptor Olr1559; Olr1559; ratchr11-42464605-42465558_ORF
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81155,069,912 - 55,070,865 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1155,069,912 - 55,070,865 (+)EnsemblGRCr8
mRatBN7.21141,600,716 - 41,601,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1141,600,716 - 41,601,669 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1150,349,786 - 50,350,739 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01143,021,087 - 43,022,040 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01142,149,722 - 42,150,675 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1156,974,721 - 56,975,674 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1155,201,147 - 55,202,100 (+)NCBILyon_Normotensive
Lyon_Hypertensive1156,109,339 - 56,110,292 (+)NCBILyon_Hypertensive
F344_StmMcwi1154,872,697 - 54,873,650 (+)NCBIF344_StmMcwi
Rnor_6.01143,699,020 - 43,699,973 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1143,699,020 - 43,699,973 (+)Ensemblrn6Rnor6.0
Rnor_5.01146,884,179 - 46,885,132 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41142,407,016 - 42,407,969 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1141,404,103 - 41,405,056 (+)NCBICelera
RGSC_v3.11142,464,604 - 42,465,558 (+)NCBI
Cytogenetic Map11q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.

Genomics

Variants

.
Variants in Or5k16
11 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:4
Count of miRNA genes:4
Interacting mature miRNAs:4
Transcripts:ENSRNOT00000070849
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
11528648Bss118Bone structure and strength QTL 1186.6582e-07femur strength trait (VT:0010010)femur ultimate displacement (CMO:0002719)115410798756845449Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat


Expression

RNA-SEQ Expression

ectoderm
integumental system
mesenchyme
renal system
1 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000070849   ⟹   ENSRNOP00000066281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1155,069,912 - 55,070,865 (+)Ensembl
mRatBN7.2 Ensembl1141,600,716 - 41,601,669 (+)Ensembl
Rnor_6.0 Ensembl1143,699,020 - 43,699,973 (+)Ensembl
RefSeq Acc Id: NM_001000049   ⟹   NP_001000049
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81155,069,912 - 55,070,865 (+)NCBI
mRatBN7.21141,600,716 - 41,601,669 (+)NCBI
Dahl_SR_JrHsd1156,974,721 - 56,975,674 (+)NCBI
Lyon_Normotensive1155,201,147 - 55,202,100 (+)NCBI
Lyon_Hypertensive1156,109,339 - 56,110,292 (+)NCBI
F344_StmMcwi1154,872,697 - 54,873,650 (+)NCBI
Rnor_6.01143,699,020 - 43,699,973 (+)NCBI
Rnor_5.01146,884,179 - 46,885,132 (+)NCBI
RGSC_v3.41142,407,016 - 42,407,969 (+)RGD
Celera1141,404,103 - 41,405,056 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000049 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066281
  ENSRNOP00000066281.1
RefSeq Acc Id: NP_001000049   ⟸   NM_001000049
- UniProtKB: M0R9V0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066281   ⟸   ENSRNOT00000070849
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R9V0-F1-model_v2 AlphaFold M0R9V0 1-317 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333528 AgrOrtholog
BioCyc Gene G2FUF-21581 BioCyc
Ensembl Genes ENSRNOG00000050423 Ensembl
  ENSRNOG00000069990 Ensembl
  ENSRNOG00000084658 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000070849 ENTREZGENE
  ENSRNOT00000070849.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_GPCR UniProtKB/TrEMBL
KEGG Report rno:288187 UniProtKB/TrEMBL
NCBI Gene 288187 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5k16 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050423 RatGTEx
  ENSRNOG00000069990 RatGTEx
  ENSRNOG00000084658 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt M0R9V0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or5k16  olfactory receptor family 5 subfamily K member 16  Olr1559  olfactory receptor 1559  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr1559  olfactory receptor 1559  LOC108352374  olfactory receptor Olfr180-like  Data merged from RGD:11491046 737654 PROVISIONAL
2016-08-02 LOC108352374  olfactory receptor Olfr180-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1559  olfactory receptor 1559   Olr1559_predicted  olfactory receptor 1559 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1559_predicted  olfactory receptor 1559 (predicted)      Symbol and Name status set to approved 70820 APPROVED