Or6e1 (olfactory receptor family 6 subfamily E member 1) - Rat Genome Database

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Gene: Or6e1 (olfactory receptor family 6 subfamily E member 1) Rattus norvegicus
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Symbol: Or6e1
Name: olfactory receptor family 6 subfamily E member 1
RGD ID: 1333203
Description: Predicted to enable isoprenoid binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR6J1 (olfactory receptor family 6 subfamily J member 1); INTERACTS WITH bisphenol A; C60 fullerene; copper atom.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1646; olfactory receptor gene Olr1646; olfactory receptor Olr1646; Olr1646
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,703,919 - 31,704,863 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1531,703,919 - 31,704,863 (-)EnsemblGRCr8
mRatBN7.21527,733,881 - 27,734,825 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,729,827 - 27,736,945 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1529,575,618 - 29,576,561 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,722,275 - 30,723,219 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01528,972,317 - 28,973,261 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01532,924,729 - 32,925,673 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1532,924,729 - 32,925,673 (-)Ensemblrn6Rnor6.0
Rnor_5.01536,736,034 - 36,736,978 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41532,344,133 - 32,345,077 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1527,316,043 - 27,316,987 (-)NCBICelera
RGSC_v3.11532,359,832 - 32,360,777 (-)NCBI
Cytogenetic Map15p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9875846  


Genomics

Comparative Map Data
Or6e1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,703,919 - 31,704,863 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1531,703,919 - 31,704,863 (-)EnsemblGRCr8
mRatBN7.21527,733,881 - 27,734,825 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,729,827 - 27,736,945 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1529,575,618 - 29,576,561 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,722,275 - 30,723,219 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01528,972,317 - 28,973,261 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01532,924,729 - 32,925,673 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1532,924,729 - 32,925,673 (-)Ensemblrn6Rnor6.0
Rnor_5.01536,736,034 - 36,736,978 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41532,344,133 - 32,345,077 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1527,316,043 - 27,316,987 (-)NCBICelera
RGSC_v3.11532,359,832 - 32,360,777 (-)NCBI
Cytogenetic Map15p13NCBI
OR6J1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,630,929 - 22,644,352 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,630,929 - 22,644,352 (-)Ensemblhg38GRCh38
GRCh371423,099,834 - 23,113,561 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,172,500 - 22,173,489 (-)NCBIBuild 36Build 36hg18NCBI36
Celera142,965,704 - 2,966,693 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,221,046 - 3,222,035 (-)NCBIHuRef
CHM1_11423,101,657 - 23,102,646 (-)NCBICHM1_1
T2T-CHM13v2.01416,828,656 - 16,842,613 (-)NCBIT2T-CHM13v2.0
Or6e1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,519,353 - 54,520,382 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,515,710 - 54,522,396 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381454,281,896 - 54,282,925 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,278,253 - 54,284,939 (-)Ensemblmm10GRCm38
MGSCv371454,901,571 - 54,902,600 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361453,239,602 - 53,240,543 (-)NCBIMGSCv36mm8
Celera1452,078,130 - 52,079,159 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.72NCBI
LOC100994199
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,082,186 - 24,083,229 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,298,672 - 23,299,715 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,469,849 - 3,471,115 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,570,785 - 21,572,051 (-)NCBIPanPan1.1PanPan1.1panPan2
OR6E1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,070,746 - 3,071,675 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,070,746 - 3,071,675 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha83,019,257 - 3,020,186 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.083,177,411 - 3,178,340 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,177,411 - 3,178,340 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.182,870,086 - 2,871,015 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.082,931,456 - 2,932,385 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,193,515 - 3,194,444 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101962528
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864034,799,707 - 34,800,786 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367221,588,272 - 1,589,207 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100151899
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,392,243 - 76,393,292 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1776,391,888 - 76,394,215 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,628,471 - 81,630,753 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OR6J1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12922,995,327 - 23,001,140 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605923,422,144 - 23,428,342 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC116913384
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11270,716,593 - 70,717,537 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Or6e1
4 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:19
Count of miRNA genes:17
Interacting mature miRNAs:19
Transcripts:ENSRNOT00000012866
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
1 1 1 16 15 1 7 26 23 2 2 1 12 1

Sequence


Ensembl Acc Id: ENSRNOT00000081045   ⟹   ENSRNOP00000075501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1532,924,729 - 32,925,673 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103249   ⟹   ENSRNOP00000092052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1527,729,827 - 27,736,945 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000124328   ⟹   ENSRNOP00000104339
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1531,703,919 - 31,704,863 (-)Ensembl
RefSeq Acc Id: NM_001000103   ⟹   NP_001000103
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,703,919 - 31,704,863 (-)NCBI
mRatBN7.21527,733,881 - 27,734,825 (-)NCBI
Rnor_6.01532,924,729 - 32,925,673 (-)NCBI
Rnor_5.01536,736,034 - 36,736,978 (-)NCBI
RGSC_v3.41532,344,133 - 32,345,077 (-)RGD
Celera1527,316,043 - 27,316,987 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000103 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000104339
  ENSRNOP00000104339.1
RefSeq Acc Id: NP_001000103   ⟸   NM_001000103
- UniProtKB: A0A8I6AET3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075501   ⟸   ENSRNOT00000081045
Ensembl Acc Id: ENSRNOP00000092052   ⟸   ENSRNOT00000103249
Ensembl Acc Id: ENSRNOP00000104339   ⟸   ENSRNOT00000124328

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAT2-F1-model_v2 AlphaFold D3ZAT2 1-314 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333203 AgrOrtholog
BioCyc Gene G2FUF-13813 BioCyc
Ensembl Genes ENSRNOG00000053618 Ensembl
  ENSRNOG00000068252 Ensembl
  ENSRNOG00000081033 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000124328 ENTREZGENE
  ENSRNOT00000124328.1 UniProtKB/TrEMBL
NCBI Gene 290202 ENTREZGENE
PhenoGen Or6e1 PhenoGen
RatGTEx ENSRNOG00000053618 RatGTEx
  ENSRNOG00000068252 RatGTEx
  ENSRNOG00000081033 RatGTEx
UniProt A0A8I6AET3 ENTREZGENE
  A0ABK0LIU6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or6e1  olfactory receptor family 6 subfamily E member 1  Olr1646  olfactory receptor 1646  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1646  olfactory receptor 1646   Olr1646_predicted  olfactory receptor 1646 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1646_predicted  olfactory receptor 1646 (predicted)      Symbol and Name status set to approved 70820 APPROVED