Olr1088 (olfactory receptor 1088) - Rat Genome Database

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Gene: Olr1088 (olfactory receptor 1088) Rattus norvegicus
Analyze
Symbol: Olr1088
Name: olfactory receptor 1088
RGD ID: 1333182
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR10R2 (olfactory receptor family 10 subfamily R member 2); INTERACTS WITH bisphenol A; 1,2-dimethylhydrazine (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: olfactory receptor 10T2; olfactory receptor 1403; olfactory receptor gene Olr1088; olfactory receptor Olr1088; Olfr1403; ratchr7-12667646-12666672_ORF
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,761,861 - 11,765,460 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl711,762,338 - 11,765,415 (-)EnsemblGRCr8
mRatBN7.2711,111,768 - 11,115,501 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl711,111,581 - 11,114,960 (-)EnsemblmRatBN7.2
Rnor_6.0714,112,362 - 14,120,466 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0714,273,214 - 14,276,303 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4712,666,672 - 12,668,738 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera79,220,623 - 9,225,613 (-)NCBICelera
RGSC_v3.1712,666,671 - 12,667,625 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Olr1088
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,761,861 - 11,765,460 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl711,762,338 - 11,765,415 (-)EnsemblGRCr8
mRatBN7.2711,111,768 - 11,115,501 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl711,111,581 - 11,114,960 (-)EnsemblmRatBN7.2
Rnor_6.0714,112,362 - 14,120,466 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0714,273,214 - 14,276,303 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4712,666,672 - 12,668,738 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera79,220,623 - 9,225,613 (-)NCBICelera
RGSC_v3.1712,666,671 - 12,667,625 (-)NCBI
Cytogenetic Map7q11NCBI
OR10R2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,472,220 - 158,480,936 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,472,220 - 158,480,936 (+)Ensemblhg38GRCh38
GRCh371158,442,010 - 158,450,726 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,716,292 - 156,717,299 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341155,262,740 - 155,263,748NCBI
Celera1131,520,712 - 131,521,719 (+)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1129,807,791 - 129,808,798 (+)NCBIHuRef
CHM1_11159,846,005 - 159,847,012 (+)NCBICHM1_1
T2T-CHM13v2.01157,609,298 - 157,618,014 (+)NCBIT2T-CHM13v2.0
Or10b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,334,017 - 78,357,117 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,353,262 - 78,356,400 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381078,498,183 - 78,521,283 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,517,428 - 78,520,566 (+)Ensemblmm10GRCm38
MGSCv371077,980,173 - 77,983,311 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361077,920,557 - 77,945,897 (+)NCBIMGSCv36mm8
Celera1079,539,505 - 79,542,635 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
LOC106150206
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546810,349,436 - 10,358,714 (+)NCBIChiLan1.0ChiLan1.0
LOC100984126
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2191,366,407 - 91,375,145 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1191,109,938 - 91,118,681 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,839,293 - 133,840,300 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11137,629,984 - 137,630,991 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1137,622,333 - 137,630,991 (+)EnsemblpanPan2panpan1.1
OR10R3C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13823,205,171 - 23,206,244 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3823,227,803 - 23,228,744 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03823,337,603 - 23,338,544 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.13823,099,814 - 23,100,755 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03823,634,775 - 23,635,716 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03824,066,505 - 24,067,446 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC100626501
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1491,788,076 - 91,792,333 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2499,823,687 - 99,831,053 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC101707891
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247942,554,922 - 2,579,992 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Olr1088
5 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:99
Interacting mature miRNAs:106
Transcripts:ENSRNOT00000012907
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat


Expression

RNA-SEQ Expression

circulatory system
ectoderm
mesenchyme
mesoderm
musculoskeletal system
renal system
reproductive system
1 1 6 2 1 4 22

Sequence


Ensembl Acc Id: ENSRNOT00000012907   ⟹   ENSRNOP00000063537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl711,762,338 - 11,765,415 (-)Ensembl
mRatBN7.2 Ensembl711,111,581 - 11,114,960 (-)Ensembl
RefSeq Acc Id: XM_063264373   ⟹   XP_063120443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,761,861 - 11,765,460 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001419556 (Get FASTA)   NCBI Sequence Viewer  
  XP_063120443 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89457 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063537
  ENSRNOP00000063537.3
RefSeq Acc Id: XP_063120443   ⟸   XM_063264373
Ensembl Acc Id: ENSRNOP00000063537   ⟸   ENSRNOT00000012907
Protein Domains
G-protein coupled receptors family 1 profile

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333182 AgrOrtholog
BioCyc Gene G2FUF-34834 BioCyc
Ensembl Genes ENSRNOG00000028146 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012907 ENTREZGENE
  ENSRNOT00000012907.8 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene 299582 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Olr1088 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028146 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6K937 ENTREZGENE, UniProtKB/TrEMBL
  F1M1K2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Olr1088  olfactory receptor 1088   Olr1088_predicted  olfactory receptor 1088 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-07 Olr1088_predicted  olfactory receptor 1088 (predicted)  Olfr1403_predicted  olfactory receptor 1403 (predicted)  Symbol and Name status set to approved 737654 APPROVED
2005-02-04 Olr1088_predicted  olfactory receptor 1088 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Olfr1403_predicted  olfactory receptor 1403 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL