Symbol:
Lynx1
Name:
Ly6/neurotoxin 1
RGD ID:
1312017
Description:
Predicted to enable acetylcholine receptor binding activity; acetylcholine receptor inhibitor activity; and ion channel inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway and regulation of neurotransmitter receptor activity. Predicted to act upstream of or within cholinergic synaptic transmission. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including LYNX1 (Ly6/neurotoxin 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC300018; ly-6/neurotoxin-like protein 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Candidate Gene For:
Bp335
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 7 108,521,783 - 108,527,012 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 7 108,521,780 - 108,527,130 (-) Ensembl GRCr8 mRatBN7.2 7 106,632,800 - 106,638,003 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 7 106,632,797 - 106,638,023 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 7 108,390,888 - 108,396,098 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 7 110,614,567 - 110,619,777 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 7 110,560,497 - 110,565,707 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 7 110,544,113 - 110,549,316 (-) NCBI Dahl_SR_JrHsd Lyon_Normotensive 7 111,490,024 - 111,495,234 (-) NCBI Lyon_Normotensive Lyon_Hypertensive 7 111,615,576 - 111,620,786 (-) NCBI Lyon_Hypertensive F344_StmMcwi 7 110,069,441 - 110,074,651 (-) NCBI F344_StmMcwi Rnor_6.0 7 115,982,877 - 115,988,121 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 7 115,982,876 - 115,988,090 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 7 115,888,263 - 115,893,505 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 7 112,862,566 - 112,867,769 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 7 103,033,948 - 103,039,151 (-) NCBI Celera RGSC_v3.1 7 112,899,790 - 112,901,986 (-) NCBI Cytogenetic Map 7 q34 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Lynx1 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Lynx1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Lynx1 Rat 1,2-dichloroethane decreases expression ISO Lynx1 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of LYNX1 mRNA CTD PMID:28960355 Lynx1 Rat 1,2-dimethylhydrazine multiple interactions ISO Lynx1 (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LYNX1 mRNA CTD PMID:22206623 Lynx1 Rat 17alpha-ethynylestradiol multiple interactions ISO Lynx1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LYNX1 mRNA CTD PMID:17942748 Lynx1 Rat 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of LYNX1 mRNA; [estradiol 3-benzoate co-treated more ... CTD PMID:26496021|PMID:32741896 Lynx1 Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of LYNX1 mRNA CTD PMID:32145629 Lynx1 Rat 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of LYNX1 mRNA CTD PMID:32741896 Lynx1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Lynx1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Lynx1 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Lynx1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Lynx1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Lynx1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LYNX1 mRNA CTD PMID:17942748 Lynx1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of LYNX1 mRNA CTD PMID:33387578 Lynx1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO LYNX1 (Homo sapiens) 6480464 [[Defoliants, Chemical results in increased abundance of Agent Orange] which results in increased abundance of more ... CTD PMID:33849548 Lynx1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of LYNX1 mRNA CTD PMID:32109520 Lynx1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Lynx1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of LYNX1 mRNA CTD PMID:21570461 Lynx1 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Lynx1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Lynx1 Rat 3,3',5,5'-tetrabromobisphenol A decreases expression ISO Lynx1 (Mus musculus) 6480464 tetrabromobisphenol A results in decreased expression of LYNX1 mRNA CTD PMID:25172293 Lynx1 Rat 4-hydroxyphenyl retinamide decreases expression ISO Lynx1 (Mus musculus) 6480464 Fenretinide results in decreased expression of LYNX1 mRNA CTD PMID:28973697 Lynx1 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of LYNX1 mRNA CTD PMID:24780913|PMID:25825206 Lynx1 Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of LYNX1 mRNA CTD PMID:31881176 Lynx1 Rat acetylcholine multiple interactions EXP 6480464 LYNX1 protein promotes the reaction [Acetylcholine results in increased activity of [CHRNA1 protein binds to more ... CTD PMID:19619141 Lynx1 Rat acrylamide decreases expression ISO Lynx1 (Mus musculus) 6480464 Acrylamide results in decreased expression of LYNX1 mRNA CTD PMID:29261810 Lynx1 Rat aflatoxin B1 increases expression ISO Lynx1 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of LYNX1 mRNA CTD PMID:19770486 Lynx1 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of LYNX1 mRNA CTD PMID:35163327 Lynx1 Rat alpha-Zearalanol decreases expression EXP 6480464 Zeranol results in decreased expression of LYNX1 mRNA CTD PMID:35163327 Lynx1 Rat arsane multiple interactions ISO LYNX1 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of LYNX1 more ... CTD PMID:32525701 Lynx1 Rat arsenic atom multiple interactions ISO LYNX1 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of LYNX1 more ... CTD PMID:32525701 Lynx1 Rat avobenzone increases expression ISO LYNX1 (Homo sapiens) 6480464 avobenzone results in increased expression of LYNX1 mRNA CTD PMID:31016361 Lynx1 Rat benzo[a]pyrene increases expression ISO Lynx1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of LYNX1 mRNA CTD PMID:22228805 Lynx1 Rat benzo[a]pyrene decreases methylation ISO LYNX1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of LYNX1 promoter CTD PMID:27901495 Lynx1 Rat benzo[a]pyrene increases methylation ISO LYNX1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of LYNX1 exon CTD PMID:27901495 Lynx1 Rat benzo[a]pyrene affects methylation ISO LYNX1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of LYNX1 5' UTR CTD PMID:27901495 Lynx1 Rat bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... CTD PMID:31199487 Lynx1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Lynx1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of LYNX1 mRNA CTD PMID:34319233 Lynx1 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of LYNX1 mRNA CTD PMID:26496021 Lynx1 Rat bisphenol A increases expression ISO Lynx1 (Mus musculus) 6480464 bisphenol A results in increased expression of LYNX1 mRNA CTD PMID:32156529 Lynx1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of LYNX1 mRNA CTD PMID:32145629 Lynx1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of LYNX1 mRNA CTD PMID:25181051|PMID:30816183|PMID:34947998 Lynx1 Rat Butylbenzyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... CTD PMID:31199487 Lynx1 Rat C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of LYNX1 mRNA CTD PMID:19167457 Lynx1 Rat cantharidin decreases expression ISO Lynx1 (Mus musculus) 6480464 Cantharidin results in decreased expression of LYNX1 mRNA CTD PMID:36907384 Lynx1 Rat choline multiple interactions ISO Lynx1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 Lynx1 Rat cisplatin increases expression ISO LYNX1 (Homo sapiens) 6480464 Cisplatin results in increased expression of LYNX1 mRNA CTD PMID:27392435 Lynx1 Rat cisplatin multiple interactions ISO LYNX1 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of LYNX1 mRNA CTD PMID:27392435 Lynx1 Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of LYNX1 mRNA CTD PMID:26577399 Lynx1 Rat Dibutyl phosphate affects expression ISO LYNX1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of LYNX1 mRNA CTD PMID:37042841 Lynx1 Rat dibutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... CTD PMID:31199487 Lynx1 Rat diethyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... CTD PMID:31199487 Lynx1 Rat diisobutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... CTD PMID:31199487 Lynx1 Rat diisononyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated more ... CTD PMID:31199487 Lynx1 Rat diisononyl phthalate increases expression ISO Lynx1 (Mus musculus) 6480464 diisononyl phthalate results in increased expression of LYNX1 mRNA CTD PMID:33391822 Lynx1 Rat doxorubicin decreases expression ISO Lynx1 (Mus musculus) 6480464 Doxorubicin results in decreased expression of LYNX1 mRNA CTD PMID:39631538 Lynx1 Rat epibatidine multiple interactions EXP 6480464 LYNX1 protein promotes the reaction [epibatidine binds to and results in increased activity of [CHRNA1 more ... CTD PMID:19619141 Lynx1 Rat ethanol affects splicing ISO Lynx1 (Mus musculus) 6480464 Ethanol affects the splicing of LYNX1 mRNA CTD PMID:30319688 Lynx1 Rat folic acid multiple interactions ISO Lynx1 (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LYNX1 mRNA; [Methionine deficiency co-treated more ... CTD PMID:20938992|PMID:22206623 Lynx1 Rat furan decreases expression EXP 6480464 furan results in decreased expression of LYNX1 mRNA CTD PMID:27387713 Lynx1 Rat imidacloprid multiple interactions EXP 6480464 LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to more ... CTD PMID:19619141 Lynx1 Rat indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of LYNX1 mRNA CTD PMID:21396975 Lynx1 Rat inulin multiple interactions ISO Lynx1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of LYNX1 mRNA CTD PMID:36331819 Lynx1 Rat L-methionine multiple interactions ISO Lynx1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 Lynx1 Rat lipopolysaccharide multiple interactions ISO LYNX1 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of LYNX1 mRNA CTD PMID:35811015 Lynx1 Rat maneb multiple interactions ISO Lynx1 (Mus musculus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of LYNX1 mRNA CTD PMID:18386188 Lynx1 Rat methylmercury chloride decreases expression ISO Lynx1 (Mus musculus) 6480464 methylmercuric chloride results in decreased expression of LYNX1 mRNA CTD PMID:29261810 Lynx1 Rat nitrates multiple interactions ISO Lynx1 (Mus musculus) 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of LYNX1 more ... CTD PMID:35964746 Lynx1 Rat paraquat multiple interactions ISO Lynx1 (Mus musculus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of LYNX1 mRNA CTD PMID:18386188 Lynx1 Rat PCB138 multiple interactions ISO Lynx1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Lynx1 Rat perfluorohexanesulfonic acid increases expression ISO Lynx1 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of LYNX1 mRNA CTD PMID:37995155 Lynx1 Rat perfluorononanoic acid decreases expression ISO Lynx1 (Mus musculus) 6480464 perfluoro-n-nonanoic acid results in decreased expression of LYNX1 mRNA CTD PMID:40194260 Lynx1 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Lynx1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of LYNX1 mRNA CTD PMID:36331819 Lynx1 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of LYNX1 mRNA CTD PMID:35163327 Lynx1 Rat phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of LYNX1 mRNA CTD PMID:31324951 Lynx1 Rat rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of LYNX1 mRNA CTD PMID:28374803 Lynx1 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO LYNX1 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of LYNX1 mRNA CTD PMID:35811015 Lynx1 Rat silicon dioxide decreases expression ISO LYNX1 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of LYNX1 mRNA CTD PMID:25895662 Lynx1 Rat sodium arsenate multiple interactions ISO LYNX1 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of LYNX1 more ... CTD PMID:32525701 Lynx1 Rat sodium arsenite increases expression ISO LYNX1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of LYNX1 mRNA CTD PMID:34032870 Lynx1 Rat sulforaphane increases expression ISO Lynx1 (Mus musculus) 6480464 sulforaphane results in increased expression of LYNX1 mRNA CTD PMID:30529165 Lynx1 Rat testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of LYNX1 mRNA CTD PMID:32741896 Lynx1 Rat tetrachloromethane affects expression ISO Lynx1 (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of LYNX1 mRNA CTD PMID:17484886 Lynx1 Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of LYNX1 mRNA CTD PMID:23411599 Lynx1 Rat titanium dioxide decreases expression ISO Lynx1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of LYNX1 mRNA CTD PMID:23557971|PMID:35295148 Lynx1 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of LYNX1 mRNA CTD PMID:33387578 Lynx1 Rat trimethyltin decreases expression ISO Lynx1 (Mus musculus) 6480464 trimethyltin results in decreased expression of LYNX1 mRNA CTD PMID:24002884 Lynx1 Rat valproic acid increases methylation ISO LYNX1 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of LYNX1 gene CTD PMID:29154799 Lynx1 Rat valproic acid increases expression ISO Lynx1 (Mus musculus) 6480464 Valproic Acid results in increased expression of LYNX1 mRNA CTD PMID:21427059|PMID:29261810