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Gene: Rassf3 (Ras association domain family member 3) Rattus norvegicus

Analyze

Symbol:

Rassf3

Name:

Ras association domain family member 3

RGD ID:

1311450

Description:

Predicted to enable identical protein binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human RASSF3 (Ras association domain family member 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC362886; Ras association (RalGDS/AF-6) domain family 3; Ras association (RalGDS/AF-6) domain family member 3; ras association domain-containing protein 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	58,821,360 - 58,886,020 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	58,821,360 - 58,886,020 (-)	Ensembl				GRCr8
mRatBN7.2	7	56,935,888 - 57,000,554 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	56,935,973 - 57,000,553 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	58,846,697 - 58,911,402 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	61,049,570 - 61,114,276 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	60,827,272 - 60,891,983 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	7	60,872,949 - 60,937,657 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	7	61,743,948 - 61,808,654 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	7	61,882,980 - 61,947,687 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	7	60,475,548 - 60,540,257 (-)	NCBI		F344_StmMcwi
Rnor_6.0	7	63,513,825 - 63,578,499 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	63,513,910 - 63,578,490 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	63,737,721 - 63,801,766 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	60,719,224 - 60,783,887 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	53,678,845 - 53,743,337 (-)	NCBI		Celera
RGSC_v3.1	7	60,742,406 - 60,804,477 (-)	NCBI
Cytogenetic Map	7	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Familial Prostate Cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

choline (ISO)

cobalt dichloride (EXP)

copper atom (EXP)

copper(0) (EXP)

coumestrol (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

Enterolactone (ISO)

entinostat (ISO)

ethanol (ISO)

fluoranthene (ISO)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

GSK-J4 (ISO)

kojic acid (ISO)

L-methionine (ISO)

methoxychlor (EXP)

methylparaben (ISO)

N,N-diethyl-m-toluamide (EXP)

O-methyleugenol (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

pirinixic acid (ISO)

rac-lactic acid (ISO)

rotenone (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sunitinib (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

signal transduction (IBA,IEA)

Cellular Component

cytoplasm (IBA)

cytoskeleton (IEA)

cytosol (IEA,ISO)

microtubule (IEA)

Molecular Function

identical protein binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:20920251

Genomics

Comparative Map Data

Rassf3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	58,821,360 - 58,886,020 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	58,821,360 - 58,886,020 (-)	Ensembl				GRCr8
mRatBN7.2	7	56,935,888 - 57,000,554 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	56,935,973 - 57,000,553 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	58,846,697 - 58,911,402 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	61,049,570 - 61,114,276 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	60,827,272 - 60,891,983 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	7	60,872,949 - 60,937,657 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	7	61,743,948 - 61,808,654 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	7	61,882,980 - 61,947,687 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	7	60,475,548 - 60,540,257 (-)	NCBI		F344_StmMcwi
Rnor_6.0	7	63,513,825 - 63,578,499 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	63,513,910 - 63,578,490 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	63,737,721 - 63,801,766 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	60,719,224 - 60,783,887 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	53,678,845 - 53,743,337 (-)	NCBI		Celera
RGSC_v3.1	7	60,742,406 - 60,804,477 (-)	NCBI
Cytogenetic Map	7	q22	NCBI

RASSF3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	64,506,964 - 64,697,564 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	64,507,001 - 64,697,567 (+)	Ensembl			hg38	GRCh38
GRCh37	12	65,004,275 - 65,091,344 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	63,290,560 - 63,375,459 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	63,290,559 - 63,375,459	NCBI
Celera	12	64,669,061 - 64,754,040 (+)	NCBI		Celera
Cytogenetic Map	12	q14.2	NCBI
HuRef	12	62,056,161 - 62,143,319 (+)	NCBI		HuRef
CHM1_1	12	64,971,222 - 65,058,272 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	64,485,586 - 64,676,600 (+)	NCBI		T2T-CHM13v2.0

Rassf3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	121,246,255 - 121,312,220 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	121,246,255 - 121,312,252 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	121,410,350 - 121,476,250 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	121,410,350 - 121,476,347 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	120,847,406 - 120,913,306 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	120,813,410 - 120,879,310 (-)	NCBI		MGSCv36	mm8
Celera	10	123,791,135 - 123,860,972 (-)	NCBI		Celera
Cytogenetic Map	10	D2	NCBI
cM Map	10	69.7	NCBI

Rassf3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	11,441,054 - 11,449,423 (+)	Ensembl
ChiLan1.0	NW_004955458	11,400,655 - 11,451,796 (+)	NCBI	ChiLan1.0	ChiLan1.0

RASSF3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	29,671,338 - 29,761,783 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	29,668,109 - 29,755,075 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	24,225,855 - 24,312,891 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	24,730,054 - 24,740,929 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	24,726,821 - 24,914,256 (-)	Ensembl			panPan2	panpan1.1

RASSF3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	7,323,272 - 7,353,378 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	7,212,460 - 7,351,395 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	7,216,311 - 7,288,982 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	7,391,136 - 7,463,789 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	7,322,356 - 7,463,785 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	7,256,809 - 7,329,001 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	7,509,203 - 7,581,530 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	7,639,690 - 7,712,109 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rassf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	51,149,785 - 51,215,363 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936545	2,894,755 - 2,962,000 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936545	2,894,761 - 2,961,994 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RASSF3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	29,025,549 - 29,113,890 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	28,949,787 - 29,113,894 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RASSF3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	60,289,751 - 60,374,220 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	60,289,680 - 60,375,600 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	185,399,844 - 185,485,784 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rassf3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624802	3,683,105 - 3,749,173 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rassf3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	199,429,117 - 199,901,288 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rassf3
231 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	694
Count of miRNA genes:	286
Interacting mature miRNAs:	363
Transcripts:	ENSRNOT00000007295
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	23807606	68807606	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	45113903	90113903	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	10517086	62346019	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	26638057	71638057	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	24179478	86817926	Rat
10059605	Kidm47	Kidney mass QTL 47	2.91	0.05	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	49137999	67614020	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	51700643	96700643	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
1298525	Cm1	Cardiac mass QTL 1	2.7		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	7	56625161	101625161	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	10112916	60150541	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	39845902	84845902	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	32998702	77998702	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
2317059	Aia15	Adjuvant induced arthritis QTL 15	2.46		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	49682832	63890004	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	36178764	81178764	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	55498584	105834451	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	48475049	93475049	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	36178764	81178764	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
70190	Mcs6	Mammary carcinoma susceptibility QTL 6	2.29		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	28624575	65788017	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	21541977	86817926	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
738033	Anxrr6	Anxiety related response QTL 6	4.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	7	17460447	62460447	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
2303582	Gluco53	Glucose level QTL 53	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	7	48603087	93603087	Rat
70207	Niddm31	Non-insulin dependent diabetes mellitus QTL 31	3.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	20057232	65057232	Rat
61439	Cia8	Collagen induced arthritis QTL 8	5.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	7	27182914	72182914	Rat

Markers in Region

RH128926

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	56,936,010 - 56,936,162 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	63,513,948 - 63,514,099	NCBI	Rnor6.0
Rnor_5.0	7	63,737,838 - 63,737,989	UniSTS	Rnor5.0
RGSC_v3.4	7	60,719,262 - 60,719,413	UniSTS	RGSC3.4
Celera	7	53,678,883 - 53,679,034	UniSTS
RH 3.4 Map	5	256.3	UniSTS
Cytogenetic Map	7	q22	UniSTS

RH141302

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	56,995,448 - 56,995,629 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	63,573,392 - 63,573,572	NCBI	Rnor6.0
Rnor_5.0	7	63,796,655 - 63,796,835	UniSTS	Rnor5.0
RGSC_v3.4	7	60,778,786 - 60,778,966	UniSTS	RGSC3.4
Celera	7	53,738,236 - 53,738,416	UniSTS
Cytogenetic Map	7	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	16	12	150	247	91	90	65	139	59	22	485	331	11	226	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007295 ⟹ ENSRNOP00000007295

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	58,821,360 - 58,886,020 (-)	Ensembl
mRatBN7.2 Ensembl	7	56,935,973 - 57,000,553 (-)	Ensembl
Rnor_6.0 Ensembl	7	63,513,910 - 63,578,490 (-)	Ensembl

RefSeq Acc Id:

NM_001108747 ⟹ NP_001102217

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	58,821,360 - 58,886,020 (-)	NCBI
mRatBN7.2	7	56,935,888 - 57,000,554 (-)	NCBI
Dahl_SR_JrHsd	7	60,872,949 - 60,937,657 (-)	NCBI
Lyon_Normotensive	7	61,743,948 - 61,808,654 (-)	NCBI
Lyon_Hypertensive	7	61,882,980 - 61,947,687 (-)	NCBI
F344_StmMcwi	7	60,475,548 - 60,540,257 (-)	NCBI
Rnor_6.0	7	63,513,910 - 63,578,490 (-)	NCBI
Rnor_5.0	7	63,737,721 - 63,801,766 (-)	NCBI
RGSC_v3.4	7	60,719,224 - 60,783,887 (-)	RGD
Celera	7	53,678,845 - 53,743,337 (-)	RGD

Sequence:

show sequence

GGGACTGGAGGGCGGCTTGAGCGGCGGCCGCAGCTGCAGCTGGACGGCCGGCCGGCGGCTCGGG
GCCGCGCGCCGGGAACCTCACGGGGCGGTCGGGCGCCGCACCCCGGCCTGGCCGCCTGCGCCCC
GGGGAGGCCCCCTGAGCGCAACCGGACCAGCAGCATGAGCAGCGGCTACAGCAGCCTCGAGGAG
GACGCGGAGGATTTTTTCTTCACCGCCAGGACCTCCTTCTTCAGGAGAGCGCCTCCGGGCAAGT
CCCGTTCGGGTCAGCCGGATGTGGAGAAGGAGAAGGAAACACACAATTACCTCAGCAAAGAGGA
AATCAAAGAGAAAGTGCATAAGTACAATTTAGCCGTCACAGATAAGCTGAAGATGACCTTAAAT
TCAAACGGGATTTACACTGGCTTCATTAAGGTGCAGATGGAACTCTGCAAACCTGCCCAGACCC
CTGCCAACCCCAGCAGCAGTGGCTGCATGAACACGCTTCATATCAGCAGCACAAACACCGTGGG
AGACGTGATCGACGCGCTGCTCAAGAAGTTTCAGGTGACCGAGAGTCCCACCAAGTTTGCGCTT
TATAAGCGTTGTCACAGGGAAGACCAAGAACACCCGCTGTACCTGCGTTTGGTAGCAGGGCCCA
GAACCGACACGCTTAGTTTTGTTCTTCGAGAACACGAAATTGGAGAGTGGGAAGCCTTCAGCCT
CCCGGAGCTGCAGAACTTCTTGCGCATCTTGGACAAGGAAGAGGACGAACAGCTACAGAGCCTG
AAGCGGCGCTATACAGCCTACAGGCAGAAGCTGGAGGAAGCCCTGGGCGAGGTGTGGAAGCCAG
GCTAAGGCTCCTCCTGCCAGGAAGGCACAGCTCGGGACGCATGAGAGAGCCGCATTGATTGCCT
CTCTTCTCGGAGAGCTGTCTTCGTGCCCCGCCGTGCTAGGGTCCTCCTCTTTCCTCTGTACACA
CAGTTCTGAGCCTGGTCACGCAGCAGCCTGCGCCTCACGGATTGGCACAAGGGACTCTGCAAGC
TTGTTCTGTTAAGCGACGTTACCTCTTGCAAGCTGTGAGCCTGTGCGCGTCGGGCACGCCCTGG
AGTACATGGACGCATGAACTCCGGGTTGATGTCCTCTGTTTTCTTCTAGTTGCTTTAATGATGT
GATTTTGGTAAGCTTCAGGGTGCGACGATGAGCTTTAAGAAGCGATCTCTGAGTTCTTGTCCTA
CGGGGAAACTACCTGCTTGTTCTTGTTCTCCGTTAGAGCAGACTACCCACAAGAATGAAAGACA
CAGGAATTTAGGAACTCTGGGGGAGTGGGAAAAGATTCCGGAAGAGTTTTGACAATAAAGAAAG
TAAAGAGCATGTAGGGGAAGATAGAGGGAGGCGAGGGCCCAGGGCCTGGGGAGGTGGCTTGGTT
TCTAAGTTAGTGTTAGAGGAGAAAGGTGTTTGTCTGGAAAGGAGCTGAGAGCATTCAGGATTGA
TGCTGAGCTCAGCTAAAGATTGCCTAATTTGCTAGTGGTAAAACGTGAGGTCAGGGCCAAAGAG
CTTGGAGCTAATAAACCCAAAGGAGGGGTCCACGAACTATGCTGACCTACAGTGGATTTGACCT
TGACCATAGGTTGGCTGGCCTCCGCTGGATCTCACCTGCTCATCCATTCTGGCGTGGAGTGGAT
GGCCTGGGGTTTAGCTTCTCTGTGTAGGTGGGGCCTGACCGTGTGCTGATTCCTGTTACCTTAG
GTTCCCCCTCCCCCCGCAGAGGTTGCTCTCAGAGTTAAAAAGGAGTTGGAGTAAGGGCAGCTGC
TTCCGCTCAGCTGTTAGCTAGAAGCAGCAGCAAGGCCGGGCTCACAGCACACTTTGTGACAATC
ATCCTCTTCCCGTTTATTCCACCCTTCCTTTTCCCTACCCCCCTCACCCTTTTGCCCCCCACCA
GCCCCAAATCATTCTCCAAAGTTCTTATGAAGTAGAAGACAGGGATGTTGATTAAAGGCCGCAT
CCTTGCCTCTTAAGAGACATAACTAAGGGCCCCAAGGAAGGAAAGTCCACACCCAGCTGGCCGC
ACAGCAGGCGTTCATTATGGAACTGTTCTAACACAAGTATGCATGTTCCTCCCAACCAAAGAGA
CGCGTGTGCAATAGACAGGCTCGATGGCCTCCTTTTCTGCAGCAGCCTGCAAATCAGAGAGCGG
AGGGAAGGTTGTTCCGTGCTTCTGGAGGGGCCTTACAGTCGGTCTGTCTCTAGTCTAGATAGAT
TGTTGTTGTTTATAAATTCCCAAGGAATTGTTAACATGGTGACACCTGACGGAATCGTTTGGAA
ATTCCAAGGTGCTCCAGCTCTTTGCCTTTCTATGAACCGTGCCTTTGATGGAGAGTCTGTCCCT
TCGAGGTGGCTTGTCCCCCCCCTGACTTGTCAGAGATGTCACCCCGTGGGAGGCAGATCCAAGT
GTGGGTAATGCTTCGCAAGCTCCTGAGACAATCGGATCTTCTAAGCTATTAGGAAGAGATGGGG
GTGGAAACACAGCTAGCTATAAAATATGAATGGCACATCTTGTTTAATTTTGCATGTGATTTCT
TTTCTGTGCATCAGTGAGGTTTAGTGACATTGTCATCCAACACGCTGCCTTTGTTGTTCAGGGA
ATGCCTTCATGGTTCTTGTACTGGTTTTACTATTCAGACTAAGGCTTGGGTTTTGCGTACACCG
CCACCAGCCACCTGGTCCCCTAATTACTCCTCCTAGCGTGCTTAGCATCTGCAAAGCATTCGTT
TCTCCGATTAAGACACTGTTAGACCATAAAGTAGCAGCTGATGGGTATCTGTGAATTTTTTTTT
TTTTACTTGAAGTAGACTGTATGAAGCAGCACCCTCCTCTGTCCTCATCCGAACCTCGCTCCAT
GGCGTGTGCCCCACACCTTGTGTCTCGGAAAGGTCACTGGATGGCACTCTGTCAGCTCGTGGCT
CCTGAAGACTGATGTTCTCTCCCAAACACTGGTCACTACAGCAGCAGGTTTAAAGCCTGAAGGA
AGAAAAAGGCTCCAGAGGCAAAGATCTAAGAAGAAACCCCTGGTTCAGATCCTTAGGGAGCGAA
GCTTTGCTGCCATCCTGATTTCTCTTCGGAACGTGACGATGGTACAGGAACGGCGTGAGGCGAA
GGCGGCTGCCGAGGGGCGTTTTAGATCTAAAGTTCAGAGCTATATTTATGAGTTTAAGTTTTAT
TTTTATAGGGCAGATTTTTTTTTCTCCCCTGAAATTGTGTCTGGAATGGCAAAATTGTTTCTGT
TATTAAAAACCGAAGTTGTTAGTTGA

hide sequence

RefSeq Acc Id:

XM_039079486 ⟹ XP_038935414

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	58,821,442 - 58,831,604 (-)	NCBI
mRatBN7.2	7	56,935,894 - 56,946,025 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102217	(Get FASTA)	NCBI Sequence Viewer
	XP_038935414	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM16550	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007295
	ENSRNOP00000007295.6

RefSeq Acc Id:

NP_001102217 ⟸ NM_001108747

- UniProtKB:

D4ACL6 (UniProtKB/TrEMBL), A6IGZ8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSGYSSLEEDAEDFFFTARTSFFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNLA
VTDKLKMTLNSNGIYTGFIKVQMELCKPAQTPANPSSSGCMNTLHISSTNTVGDVIDALLKKFQ
VTESPTKFALYKRCHREDQEHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILD
KEEDEQLQSLKRRYTAYRQKLEEALGEVWKPG

hide sequence

Ensembl Acc Id:

ENSRNOP00000007295 ⟸ ENSRNOT00000007295

RefSeq Acc Id:	XP_038935414 ⟸ XM_039079486
- Peptide Label:	isoform X1

Protein Domains

Ras-associating SARAH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ACL6-F1-model_v2	AlphaFold	D4ACL6	1-224	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695226

Promoter ID:

EPDNEW_R5750

Type:

initiation region

Name:

Rassf3_1

Description:

Ras association domain family member 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	63,578,484 - 63,578,544	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311450	AgrOrtholog
BioCyc Gene	G2FUF-33872	BioCyc
Ensembl Genes	ENSRNOG00000005388	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000007295	ENTREZGENE
	ENSRNOT00000007295.8	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.110	UniProtKB/TrEMBL
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/TrEMBL
InterPro	C-RASSF	UniProtKB/TrEMBL
	Ras-assoc	UniProtKB/TrEMBL
	SARAH	UniProtKB/TrEMBL
	Ubiquitin-rel_dom	UniProtKB/TrEMBL
KEGG Report	rno:362886	UniProtKB/TrEMBL
NCBI Gene	362886	ENTREZGENE
PANTHER	PTHR22738	UniProtKB/TrEMBL
	PTHR22738:SF8	UniProtKB/TrEMBL
Pfam	Nore1-SARAH	UniProtKB/TrEMBL
	PF00788	UniProtKB/TrEMBL
PhenoGen	Rassf3	PhenoGen
PROSITE	PS50200	UniProtKB/TrEMBL
	SARAH	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005388	RatGTEx
SMART	SM00314	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54236	UniProtKB/TrEMBL
UniProt	A6IGZ8	ENTREZGENE, UniProtKB/TrEMBL
	D4ACL6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-03	Rassf3	Ras association domain family member 3	Rassf3	Ras association (RalGDS/AF-6) domain family member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-25	Rassf3	Ras association (RalGDS/AF-6) domain family member 3	Rassf3_predicted	Ras association (RalGDS/AF-6) domain family 3 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Rassf3_predicted	Ras association (RalGDS/AF-6) domain family 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD