Arhgef18 (Rho/Rac guanine nucleotide exchange factor 18) - Rat Genome Database

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Gene: Arhgef18 (Rho/Rac guanine nucleotide exchange factor 18) Rattus norvegicus
Analyze
Symbol: Arhgef18
Name: Rho/Rac guanine nucleotide exchange factor 18
RGD ID: 1311448
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in negative regulation of stress fiber assembly and protein localization to cell-cell junction. Predicted to act upstream of or within actin cytoskeleton organization; regulation of cell shape; and small GTPase-mediated signal transduction. Predicted to be located in apical part of cell. Human ortholog(s) of this gene implicated in retinitis pigmentosa 78. Orthologous to human ARHGEF18 (Rho/Rac guanine nucleotide exchange factor 18); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC304193; rho guanine nucleotide exchange factor 18; rho/rac guanine nucleotide exchange factor (GEF) 18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8126,192,958 - 6,300,997 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl126,128,661 - 6,300,997 (+)EnsemblGRCr8
mRatBN7.2121,395,035 - 1,503,082 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,395,088 - 1,503,081 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx122,058,113 - 2,167,374 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0122,681,667 - 2,790,942 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,453,728 - 1,562,982 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0121,889,252 - 1,998,128 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl121,889,331 - 1,998,127 (+)Ensemblrn6Rnor6.0
Rnor_5.0124,056,145 - 4,161,174 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4122,712,198 - 2,855,137 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera123,250,654 - 3,359,236 (+)NCBICelera
RGSC_v3.1122,713,997 - 2,740,671 (-)NCBI
Cytogenetic Map12p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14512443   PMID:18570454   PMID:22006950   PMID:25753039  


Genomics

Comparative Map Data
Arhgef18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8126,192,958 - 6,300,997 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl126,128,661 - 6,300,997 (+)EnsemblGRCr8
mRatBN7.2121,395,035 - 1,503,082 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,395,088 - 1,503,081 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx122,058,113 - 2,167,374 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0122,681,667 - 2,790,942 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,453,728 - 1,562,982 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0121,889,252 - 1,998,128 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl121,889,331 - 1,998,127 (+)Ensemblrn6Rnor6.0
Rnor_5.0124,056,145 - 4,161,174 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4122,712,198 - 2,855,137 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera123,250,654 - 3,359,236 (+)NCBICelera
RGSC_v3.1122,713,997 - 2,740,671 (-)NCBI
Cytogenetic Map12p12NCBI
ARHGEF18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38197,348,937 - 7,479,989 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl197,348,937 - 7,472,485 (+)Ensemblhg38GRCh38
GRCh37197,413,842 - 7,537,364 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,351,866 - 7,443,371 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34197,351,865 - 7,443,370NCBI
Celera197,331,115 - 7,409,876 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef197,128,031 - 7,179,714 (+)NCBIHuRef
HuRef197,186,895 - 7,208,106 (+)NCBIHuRef
CHM1_1197,459,437 - 7,537,381 (+)NCBICHM1_1
T2T-CHM13v2.0197,341,415 - 7,480,103 (+)NCBIT2T-CHM13v2.0
Arhgef18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,403,339 - 3,506,601 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl83,403,415 - 3,506,601 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3883,353,338 - 3,456,601 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,353,415 - 3,456,601 (+)Ensemblmm10GRCm38
MGSCv3783,393,008 - 3,456,600 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3683,393,008 - 3,456,600 (+)NCBIMGSCv36mm8
Celera83,618,863 - 3,682,398 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.92NCBI
Arhgef18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555631,746,838 - 1,772,772 (-)Ensembl
ChiLan1.0NW_0049555631,745,202 - 1,823,411 (-)NCBIChiLan1.0ChiLan1.0
ARHGEF18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22012,057,368 - 12,143,966 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11911,175,668 - 11,262,115 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0196,677,468 - 6,763,286 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1197,580,173 - 7,622,096 (+)NCBIPanPan1.1PanPan1.1panPan2
ARHGEF18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,196,670 - 52,281,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2052,201,007 - 52,283,000 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2052,001,555 - 52,087,194 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02052,726,796 - 52,812,572 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2052,726,780 - 52,812,567 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12051,930,590 - 52,016,159 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02052,374,118 - 52,459,723 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02052,604,731 - 52,690,664 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arhgef18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118213,262,232 - 213,334,821 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365884,514,691 - 4,572,518 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365884,522,517 - 4,572,551 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGEF18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,651,100 - 71,747,409 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1271,651,096 - 71,747,513 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2272,176,541 - 72,198,429 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGEF18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.166,846,595 - 6,972,701 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl66,869,318 - 6,973,989 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666081898,649 - 1,027,439 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgef18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624828536,926 - 605,119 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624828529,529 - 604,996 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgef18
1001 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:267
Count of miRNA genes:170
Interacting mature miRNAs:213
Transcripts:ENSRNOT00000066281
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12115486827Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1357337Gluco3Glucose level QTL 30.0004adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)12116966671Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
61334Gluco17Glucose level QTL 176.3adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)12116966671Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12111869600Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat

Markers in Region
D12Got218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,472,333 - 1,472,460 (+)MAPPERmRatBN7.2
Rnor_6.0121,967,808 - 1,967,934NCBIRnor6.0
Rnor_5.0124,130,854 - 4,130,980UniSTSRnor5.0
RGSC_v3.4122,742,743 - 2,742,869UniSTSRGSC3.4
Celera123,328,176 - 3,328,302UniSTS
Cytogenetic Map12p12UniSTS
RH131614  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,502,850 - 1,503,054 (+)MAPPERmRatBN7.2
Rnor_6.0121,997,897 - 1,998,100NCBIRnor6.0
Rnor_5.0124,160,943 - 4,161,146UniSTSRnor5.0
RGSC_v3.4122,712,225 - 2,712,428UniSTSRGSC3.4
Celera123,359,006 - 3,359,209UniSTS
Cytogenetic Map12p12UniSTS
RH131442  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8126,277,170 - 6,277,450 (+)Marker Load Pipeline
mRatBN7.2121,479,254 - 1,479,534 (+)MAPPERmRatBN7.2
Rnor_6.0121,974,728 - 1,975,007NCBIRnor6.0
Rnor_5.0124,137,774 - 4,138,053UniSTSRnor5.0
RGSC_v3.4122,735,670 - 2,735,949UniSTSRGSC3.4
Celera123,335,095 - 3,335,313UniSTS
Cytogenetic Map12p12UniSTS
RH143508  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,484,736 - 1,484,868 (+)MAPPERmRatBN7.2
Rnor_6.0121,980,209 - 1,980,340NCBIRnor6.0
Rnor_5.0124,143,255 - 4,143,386UniSTSRnor5.0
RGSC_v3.4122,730,337 - 2,730,468UniSTSRGSC3.4
Celera123,340,515 - 3,340,646UniSTS
Cytogenetic Map12p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
19 12 68 168 91 90 59 152 59 6 427 254 12 146 87 101 31 18 18

Sequence


Ensembl Acc Id: ENSRNOT00000066281   ⟹   ENSRNOP00000062255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl126,193,022 - 6,300,997 (+)Ensembl
mRatBN7.2 Ensembl121,395,088 - 1,503,081 (+)Ensembl
Rnor_6.0 Ensembl121,889,331 - 1,998,127 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100968   ⟹   ENSRNOP00000089688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl126,193,022 - 6,300,997 (+)Ensembl
mRatBN7.2 Ensembl121,395,088 - 1,503,081 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110862   ⟹   ENSRNOP00000078753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl126,193,022 - 6,300,997 (+)Ensembl
mRatBN7.2 Ensembl121,395,088 - 1,503,081 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148939   ⟹   ENSRNOP00000099512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl126,128,661 - 6,300,997 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000168177   ⟹   ENSRNOP00000108312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl126,201,170 - 6,234,686 (+)Ensembl
RefSeq Acc Id: NM_001395655   ⟹   NP_001382584
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,193,022 - 6,300,997 (+)NCBI
mRatBN7.2121,395,092 - 1,503,082 (+)NCBI
RefSeq Acc Id: XM_039089307   ⟹   XP_038945235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,271,948 - 6,300,997 (+)NCBI
mRatBN7.2121,473,919 - 1,501,281 (+)NCBI
RefSeq Acc Id: XM_063271243   ⟹   XP_063127313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,192,958 - 6,300,997 (+)NCBI
RefSeq Acc Id: XM_063271244   ⟹   XP_063127314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,192,959 - 6,300,997 (+)NCBI
RefSeq Acc Id: XM_063271245   ⟹   XP_063127315
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8126,238,713 - 6,300,997 (+)NCBI
Ensembl Acc Id: ENSRNOP00000062255   ⟸   ENSRNOT00000066281
RefSeq Acc Id: XP_038945235   ⟸   XM_039089307
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZLL3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078753   ⟸   ENSRNOT00000110862
Ensembl Acc Id: ENSRNOP00000089688   ⟸   ENSRNOT00000100968
RefSeq Acc Id: NP_001382584   ⟸   NM_001395655
- UniProtKB: A0A8I5ZLL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127313   ⟸   XM_063271243
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZLL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127314   ⟸   XM_063271244
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZLL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127315   ⟸   XM_063271245
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000108312   ⟸   ENSRNOT00000168177
Ensembl Acc Id: ENSRNOP00000099512   ⟸   ENSRNOT00000148939

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LT94-F1-model_v2 AlphaFold F1LT94 1-1184 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698364
Promoter ID:EPDNEW_R8889
Type:multiple initiation site
Name:Arhgef18_1
Description:Rho/Rac guanine nucleotide exchange factor 18
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0121,889,335 - 1,889,395EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311448 AgrOrtholog
BioCyc Gene G2FUF-20405 BioCyc
Ensembl Genes ENSRNOG00000028090 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066281 ENTREZGENE
  ENSRNOT00000066281.4 UniProtKB/TrEMBL
  ENSRNOT00000100968.2 UniProtKB/TrEMBL
  ENSRNOT00000110862.2 UniProtKB/TrEMBL
  ENSRNOT00000148939 ENTREZGENE
  ENSRNOT00000148939.1 UniProtKB/TrEMBL
  ENSRNOT00000168177.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARHGEF18_PH UniProtKB/TrEMBL
  DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  PH_16 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Rho_GEF18 UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene 304193 ENTREZGENE
PANTHER RHO/RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR 18 UniProtKB/TrEMBL
  RIKEN CDNA A430078G23 GENE UniProtKB/TrEMBL
Pfam PH_16 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PhenoGen Arhgef18 PhenoGen
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028090 RatGTEx
SMART RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A0A8I5ZLL3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALJ4_RAT UniProtKB/TrEMBL
  A0ABK0L5B4_RAT UniProtKB/TrEMBL
  A0ABK0M095_RAT UniProtKB/TrEMBL
  F1LT94_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Arhgef18  Rho/Rac guanine nucleotide exchange factor 18  Arhgef18  rho/rac guanine nucleotide exchange factor (GEF) 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Arhgef18  rho/rac guanine nucleotide exchange factor (GEF) 18   Arhgef18_predicted  rho/rac guanine nucleotide exchange factor (GEF) 18 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Arhgef18_predicted  rho/rac guanine nucleotide exchange factor (GEF) 18 (predicted)      Symbol and Name status set to approved 70820 APPROVED