Ssr1 (signal sequence receptor subunit 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ssr1 (signal sequence receptor subunit 1) Rattus norvegicus
Analyze
Symbol: Ssr1
Name: signal sequence receptor subunit 1
RGD ID: 1310961
Description: Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SSR1 (signal sequence receptor subunit 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ac2-238; liver regeneration-related protein LRRG137; LOC361233; signal sequence receptor subunit alpha; signal sequence receptor, alpha; SSR-alpha; translocon-associated protein subunit alpha; TRAP-alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81727,039,203 - 27,067,352 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1727,039,269 - 27,067,348 (+)EnsemblGRCr8
mRatBN7.21726,833,720 - 26,861,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1726,833,741 - 26,861,821 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1726,692,010 - 26,707,862 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01728,295,585 - 28,311,437 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01726,640,642 - 26,656,477 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1726,882,194 - 26,898,048 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1726,858,039 - 26,873,893 (+)NCBILyon_Normotensive
Lyon_Hypertensive1726,868,748 - 26,884,598 (+)NCBILyon_Hypertensive
F344_StmMcwi1726,928,808 - 26,944,660 (+)NCBIF344_StmMcwi
Rnor_6.01727,496,369 - 27,512,781 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1727,492,220 - 27,523,912 (+)Ensemblrn6Rnor6.0
Rnor_5.01729,410,597 - 29,430,911 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41733,061,975 - 33,077,827 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1726,465,484 - 26,481,337 (+)NCBICelera
RGSC_v3.11733,060,629 - 33,111,917 (+)NCBI
Cytogenetic Map17p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (EXP)
cadmium dichloride  (EXP)
calciol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
eugenol  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
glafenine  (EXP)
hydralazine  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
nickel atom  (ISO)
nimesulide  (EXP)
Nivalenol  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP)
sodium fluoride  (ISO)
Soman  (EXP)
succimer  (ISO)
sulfadimethoxine  (EXP)
tamibarotene  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
theophylline  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21795745  


Genomics

Comparative Map Data
Ssr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81727,039,203 - 27,067,352 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1727,039,269 - 27,067,348 (+)EnsemblGRCr8
mRatBN7.21726,833,720 - 26,861,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1726,833,741 - 26,861,821 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1726,692,010 - 26,707,862 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01728,295,585 - 28,311,437 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01726,640,642 - 26,656,477 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1726,882,194 - 26,898,048 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1726,858,039 - 26,873,893 (+)NCBILyon_Normotensive
Lyon_Hypertensive1726,868,748 - 26,884,598 (+)NCBILyon_Hypertensive
F344_StmMcwi1726,928,808 - 26,944,660 (+)NCBIF344_StmMcwi
Rnor_6.01727,496,369 - 27,512,781 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1727,492,220 - 27,523,912 (+)Ensemblrn6Rnor6.0
Rnor_5.01729,410,597 - 29,430,911 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41733,061,975 - 33,077,827 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1726,465,484 - 26,481,337 (+)NCBICelera
RGSC_v3.11733,060,629 - 33,111,917 (+)NCBI
Cytogenetic Map17p12NCBI
SSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3867,281,143 - 7,313,199 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl67,268,306 - 7,347,446 (-)Ensemblhg38GRCh38
GRCh3767,281,376 - 7,313,432 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3667,232,803 - 7,258,434 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3467,232,802 - 7,258,434NCBI
Celera68,511,044 - 8,543,304 (-)NCBICelera
Cytogenetic Map6p24.3NCBI
HuRef67,157,612 - 7,189,870 (-)NCBIHuRef
CHM1_167,283,386 - 7,315,638 (-)NCBICHM1_1
T2T-CHM13v2.067,150,204 - 7,182,261 (-)NCBIT2T-CHM13v2.0
Ssr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391338,155,377 - 38,178,184 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1338,150,581 - 38,178,193 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381337,971,401 - 37,994,208 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1337,966,605 - 37,994,217 (-)Ensemblmm10GRCm38
MGSCv371338,063,270 - 38,086,059 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361337,985,476 - 38,001,623 (-)NCBIMGSCv36mm8
MGSCv361337,369,878 - 37,386,025 (-)NCBIMGSCv36mm8
Celera1339,093,049 - 39,114,041 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1317.86NCBI
Ssr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554656,540,509 - 6,557,402 (+)Ensembl
ChiLan1.0NW_0049554656,540,509 - 6,557,402 (+)NCBIChiLan1.0ChiLan1.0
SSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2521,908,087 - 21,953,252 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1617,904,511 - 17,950,147 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v067,105,729 - 7,151,072 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.167,392,565 - 7,418,260 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl67,373,460 - 7,418,260 (-)EnsemblpanPan2panpan1.1
SSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1357,276,697 - 7,303,223 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl357,264,171 - 7,303,201 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha357,281,918 - 7,306,242 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0357,358,147 - 7,384,700 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl357,345,926 - 7,384,710 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1357,213,481 - 7,237,847 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0357,240,417 - 7,264,763 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0358,572,724 - 8,597,108 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ssr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494617,000,234 - 17,036,788 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365345,269,259 - 5,293,697 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365345,269,263 - 5,305,771 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SSR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl74,652,921 - 4,685,901 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.174,662,949 - 4,685,892 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.274,675,472 - 4,698,116 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11764,879,447 - 64,905,046 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1764,879,249 - 64,922,885 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660447,228,653 - 7,272,150 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ssr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475618,229,189 - 18,247,902 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475618,229,623 - 18,247,898 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ssr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11457,017,742 - 57,034,807 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ssr1
204 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:403
Count of miRNA genes:224
Interacting mature miRNAs:277
Transcripts:ENSRNOT00000019040
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17926675540968173Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
8552966Pigfal18Plasma insulin-like growth factor 1 level QTL 188.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)171286094257860942Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172266079955604694Rat
9589151Insul30Insulin level QTL 308.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)171286094257860942Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172149899450592236Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172328632264246472Rat
9589057Scfw6Subcutaneous fat weight QTL 68.620.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)171286094257860942Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)172652205171522051Rat
9590154Scort9Serum corticosterone level QTL 923.570.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)171286094257860942Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172201970567019705Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
9590088Insglur7Insulin/glucose ratio QTL 720.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)171286094257860942Rat
1331720Rf43Renal function QTL 432.881kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)171553702528637951Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)171060469455604694Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171553702560531414Rat
7411666Foco31Food consumption QTL 3111.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)171286094257860942Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172385892668858926Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17857434232199534Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172385892668858926Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172385892668858926Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172385892668858926Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172385892668858926Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat

Markers in Region
RH133246  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21726,849,888 - 26,850,092 (+)MAPPERmRatBN7.2
Rnor_6.01727,512,484 - 27,512,687NCBIRnor6.0
Rnor_5.01729,426,713 - 29,426,916UniSTSRnor5.0
RGSC_v3.41733,078,102 - 33,078,305UniSTSRGSC3.4
Celera1726,481,612 - 26,481,815UniSTS
RH 3.4 Map17341.4UniSTS
Cytogenetic Map17p12UniSTS
RH143561  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21726,849,776 - 26,849,934 (+)MAPPERmRatBN7.2
Rnor_6.01727,512,372 - 27,512,529NCBIRnor6.0
Rnor_5.01729,426,601 - 29,426,758UniSTSRnor5.0
RGSC_v3.41733,077,990 - 33,078,147UniSTSRGSC3.4
Celera1726,481,500 - 26,481,657UniSTS
RH 3.4 Map17341.4UniSTS
Cytogenetic Map17p12UniSTS
RH141249  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21726,849,387 - 26,849,570 (+)MAPPERmRatBN7.2
Rnor_6.01727,511,983 - 27,512,165NCBIRnor6.0
Rnor_5.01729,426,212 - 29,426,394UniSTSRnor5.0
RGSC_v3.41733,077,601 - 33,077,783UniSTSRGSC3.4
Celera1726,481,111 - 26,481,293UniSTS
RH 3.4 Map4420.62UniSTS
Cytogenetic Map17p12UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 16 12 150 249 91 90 65 139 59 22 485 331 11 228 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000019040   ⟹   ENSRNOP00000019040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1727,039,273 - 27,054,658 (+)Ensembl
mRatBN7.2 Ensembl1726,833,741 - 26,849,701 (+)Ensembl
Rnor_6.0 Ensembl1727,496,406 - 27,512,207 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077994   ⟹   ENSRNOP00000071334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1727,039,273 - 27,067,348 (+)Ensembl
mRatBN7.2 Ensembl1726,833,741 - 26,861,821 (+)Ensembl
Rnor_6.0 Ensembl1727,496,353 - 27,510,918 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084090   ⟹   ENSRNOP00000070389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1727,039,269 - 27,055,845 (+)Ensembl
mRatBN7.2 Ensembl1726,833,741 - 26,851,035 (+)Ensembl
Rnor_6.0 Ensembl1727,492,220 - 27,523,912 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089736   ⟹   ENSRNOP00000070167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1727,039,269 - 27,066,747 (+)Ensembl
mRatBN7.2 Ensembl1726,833,741 - 26,861,216 (+)Ensembl
Rnor_6.0 Ensembl1727,496,472 - 27,523,912 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098549   ⟹   ENSRNOP00000093163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1726,835,438 - 26,851,035 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109967   ⟹   ENSRNOP00000083441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1727,040,972 - 27,054,658 (+)Ensembl
mRatBN7.2 Ensembl1726,835,013 - 26,850,057 (+)Ensembl
RefSeq Acc Id: NM_001008891   ⟹   NP_001008891
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81727,039,293 - 27,055,146 (+)NCBI
mRatBN7.21726,833,759 - 26,849,614 (+)NCBI
Dahl_SR_JrHsd1726,882,194 - 26,898,048 (+)NCBI
Lyon_Normotensive1726,858,039 - 26,873,893 (+)NCBI
Lyon_Hypertensive1726,868,748 - 26,884,598 (+)NCBI
F344_StmMcwi1726,928,808 - 26,944,660 (+)NCBI
Rnor_6.01727,496,406 - 27,512,209 (+)NCBI
Rnor_5.01729,410,597 - 29,430,911 (+)NCBI
RGSC_v3.41733,061,975 - 33,077,827 (+)RGD
Celera1726,465,484 - 26,481,337 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095878   ⟹   XP_038951806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81727,039,203 - 27,067,352 (+)NCBI
mRatBN7.21726,833,721 - 26,861,821 (+)NCBI
RefSeq Acc Id: XM_063276579   ⟹   XP_063132649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81727,039,203 - 27,053,324 (+)NCBI
RefSeq Acc Id: NP_001008891   ⟸   NM_001008891
- Peptide Label: precursor
- UniProtKB: Q4V7D1 (UniProtKB/TrEMBL),   F7F9K1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071334   ⟸   ENSRNOT00000077994
Ensembl Acc Id: ENSRNOP00000070167   ⟸   ENSRNOT00000089736
Ensembl Acc Id: ENSRNOP00000019040   ⟸   ENSRNOT00000019040
Ensembl Acc Id: ENSRNOP00000070389   ⟸   ENSRNOT00000084090
RefSeq Acc Id: XP_038951806   ⟸   XM_039095878
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K075 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093163   ⟸   ENSRNOT00000098549
Ensembl Acc Id: ENSRNOP00000083441   ⟸   ENSRNOT00000109967
RefSeq Acc Id: XP_063132649   ⟸   XM_063276579
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K075 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TPJ0-F1-model_v2 AlphaFold Q7TPJ0 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700397
Promoter ID:EPDNEW_R10920
Type:initiation region
Name:Ssr1_1
Description:signal sequence receptor subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01727,496,419 - 27,496,479EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310961 AgrOrtholog
BioCyc Gene G2FUF-9671 BioCyc
Ensembl Genes ENSRNOG00000014165 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077994 ENTREZGENE
  ENSRNOT00000084090 ENTREZGENE
  ENSRNOT00000089736.2 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7454159 IMAGE-MGC_LOAD
InterPro TRAP_alpha UniProtKB/Swiss-Prot
MGC_CLONE MGC:116155 IMAGE-MGC_LOAD
NCBI Gene 361233 ENTREZGENE
PANTHER TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA UniProtKB/Swiss-Prot
  TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT UniProtKB/Swiss-Prot
Pfam TRAP_alpha UniProtKB/Swiss-Prot
PhenoGen Ssr1 PhenoGen
RatGTEx ENSRNOG00000014165 RatGTEx
UniProt A0A0G2JX79_RAT UniProtKB/TrEMBL
  A0A0G2JXS8_RAT UniProtKB/TrEMBL
  A0A0G2K075 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZVE2_RAT UniProtKB/TrEMBL
  F7F9K1 ENTREZGENE, UniProtKB/TrEMBL
  Q4V7D1 ENTREZGENE, UniProtKB/TrEMBL
  Q7TPJ0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-11 Ssr1  signal sequence receptor subunit 1  Ssr1  signal sequence receptor, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ssr1  signal sequence receptor, alpha  Ssr1_predicted  signal sequence receptor, alpha (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ssr1_predicted  signal sequence receptor, alpha (predicted)      Symbol and Name status set to approved 70820 APPROVED