Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pgbd5 | Rat | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in decreased expression of PGBD5 mRNA | CTD | PMID:27840820 | Pgbd5 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Pgbd5 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of PGBD5 mRNA | CTD | PMID:22206623 | Pgbd5 | Rat | 17beta-estradiol | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of PGBD5 mRNA; [Progesterone co-treated with more ... | CTD | PMID:17404688|PMID:30165855 | Pgbd5 | Rat | 17beta-estradiol | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Estradiol results in increased expression of PGBD5 mRNA | CTD | PMID:31614463 | Pgbd5 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PGBD5 mRNA | CTD | PMID:32109520|PMID:33387578 | Pgbd5 | Rat | 3,4-dichloroaniline | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | 3,4-dichloroaniline results in increased expression of PGBD5 mRNA | CTD | PMID:24172598 | Pgbd5 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Pgbd5 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of PGBD5 mRNA | CTD | PMID:20188158 | Pgbd5 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | PGBD5 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of PGBD5 gene | CTD | PMID:31601247 | Pgbd5 | Rat | all-trans-retinoic acid | decreases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PGBD5 mRNA | CTD | PMID:21934132|PMID:33167477 | Pgbd5 | Rat | all-trans-retinoic acid | multiple interactions | ISO | Pgbd5 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PGBD5 mRNA | CTD | PMID:36189433 | Pgbd5 | Rat | benzo[a]pyrene | decreases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PGBD5 mRNA | CTD | PMID:20064835 | Pgbd5 | Rat | benzo[a]pyrene | increases methylation | ISO | PGBD5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PGBD5 exon; Benzo(a)pyrene results in increased methylation of PGBD5 more ... | CTD | PMID:27901495 | Pgbd5 | Rat | benzo[a]pyrene | affects methylation | ISO | PGBD5 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PGBD5 3' UTR | CTD | PMID:27901495 | Pgbd5 | Rat | benzo[a]pyrene | increases expression | ISO | Pgbd5 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PGBD5 mRNA | CTD | PMID:23735875 | Pgbd5 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Pgbd5 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of PGBD5 mRNA | CTD | PMID:34319233 | Pgbd5 | Rat | bisphenol A | decreases expression | ISO | Pgbd5 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PGBD5 mRNA | CTD | PMID:26063408 | Pgbd5 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PGBD5 gene | CTD | PMID:28505145 | Pgbd5 | Rat | bisphenol A | decreases methylation | ISO | Pgbd5 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of PGBD5 promoter | CTD | PMID:27312807 | Pgbd5 | Rat | bisphenol A | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PGBD5 mRNA | CTD | PMID:27685785 | Pgbd5 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PGBD5 mRNA | CTD | PMID:25181051 | Pgbd5 | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of PGBD5 mRNA | CTD | PMID:19167457 | Pgbd5 | Rat | cadmium atom | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PGBD5 more ... | CTD | PMID:29741670 | Pgbd5 | Rat | cadmium dichloride | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PGBD5 more ... | CTD | PMID:29741670 | Pgbd5 | Rat | calcitriol | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of PGBD5 mRNA | CTD | PMID:26485663 | Pgbd5 | Rat | CGP 52608 | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PGBD5 gene] | CTD | PMID:28238834 | Pgbd5 | Rat | chlorpyrifos | increases expression | ISO | Pgbd5 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of PGBD5 mRNA | CTD | PMID:37019170 | Pgbd5 | Rat | choline | multiple interactions | ISO | Pgbd5 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Pgbd5 | Rat | diuron | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Diuron metabolite results in increased expression of PGBD5 mRNA | CTD | PMID:24172598 | Pgbd5 | Rat | doxorubicin | decreases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PGBD5 mRNA | CTD | PMID:29803840 | Pgbd5 | Rat | ethanol | affects splicing | ISO | Pgbd5 (Mus musculus) | 6480464 | Ethanol affects the splicing of PGBD5 mRNA | CTD | PMID:30319688 | Pgbd5 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of PGBD5 mRNA | CTD | PMID:30307764 | Pgbd5 | Rat | folic acid | multiple interactions | ISO | Pgbd5 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Pgbd5 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PGBD5 mRNA | CTD | PMID:33387578 | Pgbd5 | Rat | glyphosate | decreases methylation | EXP | | 6480464 | Glyphosate results in decreased methylation of PGBD5 gene | CTD | PMID:31011160 | Pgbd5 | Rat | L-methionine | multiple interactions | ISO | Pgbd5 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Pgbd5 | Rat | leflunomide | decreases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of PGBD5 mRNA | CTD | PMID:28988120 | Pgbd5 | Rat | lipopolysaccharide | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PGBD5 mRNA | CTD | PMID:35811015 | Pgbd5 | Rat | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of PGBD5 mRNA | CTD | PMID:28341135 | Pgbd5 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Pgbd5 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PGBD5 mRNA | CTD | PMID:36189433 | Pgbd5 | Rat | okadaic acid | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of PGBD5 mRNA | CTD | PMID:38832940 | Pgbd5 | Rat | ozone | multiple interactions | ISO | Pgbd5 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Pgbd5 | Rat | paracetamol | affects expression | ISO | Pgbd5 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PGBD5 mRNA | CTD | PMID:17562736 | Pgbd5 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PGBD5 mRNA | CTD | PMID:33387578 | Pgbd5 | Rat | paracetamol | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PGBD5 mRNA | CTD | PMID:29067470 | Pgbd5 | Rat | pirinixic acid | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Pgbd5 | Rat | progesterone | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [Progesterone co-treated with Estradiol] results in increased expression of PGBD5 mRNA | CTD | PMID:17404688 | Pgbd5 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PGBD5 mRNA | CTD | PMID:35811015 | Pgbd5 | Rat | sodium arsenite | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PGBD5 mRNA | CTD | PMID:38568856 | Pgbd5 | Rat | sotorasib | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PGBD5 mRNA | CTD | PMID:36139627 | Pgbd5 | Rat | titanium dioxide | decreases methylation | ISO | Pgbd5 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PGBD5 promoter | CTD | PMID:35295148 | Pgbd5 | Rat | trametinib | multiple interactions | ISO | PGBD5 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of PGBD5 mRNA | CTD | PMID:36139627 | Pgbd5 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PGBD5 mRNA | CTD | PMID:33387578 | Pgbd5 | Rat | triclosan | decreases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of PGBD5 mRNA | CTD | PMID:30510588 | Pgbd5 | Rat | triptonide | increases expression | ISO | Pgbd5 (Mus musculus) | 6480464 | triptonide results in increased expression of PGBD5 mRNA | CTD | PMID:33045310 | Pgbd5 | Rat | valproic acid | increases methylation | ISO | PGBD5 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PGBD5 gene | CTD | PMID:29154799 | Pgbd5 | Rat | valproic acid | affects expression | ISO | Pgbd5 (Mus musculus) | 6480464 | Valproic Acid affects the expression of PGBD5 mRNA | CTD | PMID:17963808 | Pgbd5 | Rat | valproic acid | affects expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PGBD5 mRNA | CTD | PMID:25979313 | Pgbd5 | Rat | valproic acid | increases expression | ISO | PGBD5 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PGBD5 mRNA | CTD | PMID:23179753|PMID:24935251|PMID:28001369|PMID:29154799 | Pgbd5 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of PGBD5 gene | CTD | PMID:31079544 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||





















