Larp4b (La ribonucleoprotein 4B) - Rat Genome Database

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Pathways
Gene: Larp4b (La ribonucleoprotein 4B) Rattus norvegicus
Analyze
Symbol: Larp4b
Name: La ribonucleoprotein 4B
RGD ID: 1310713
Description: Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in positive regulation of 3'-UTR-mediated mRNA stabilization and positive regulation of translation. Predicted to be located in cytoplasm. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human LARP4B (La ribonucleoprotein 4B); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: La ribonucleoprotein domain family, member 4B; La ribonucleoprotein domain family, member 5; la-related protein 4B; Larp5; LOC307070; RGD1310713; similar to expressed sequence AI256361
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81765,813,125 - 65,908,920 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1765,830,022 - 65,908,676 (-)EnsemblGRCr8
mRatBN7.21761,138,663 - 61,217,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1764,342,474 - 64,421,256 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01768,345,568 - 68,424,348 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01762,506,614 - 62,585,282 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01763,236,007 - 63,317,298 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1763,265,407 - 63,314,019 (+)Ensemblrn6Rnor6.0
Rnor_5.01765,007,058 - 65,085,258 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41771,931,605 - 72,010,103 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1759,363,334 - 59,441,817 (+)NCBICelera
RGSC_v3.11771,943,684 - 72,020,936 (-)NCBI
Cytogenetic Map17q12.1NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasmic stress granule  (IBA,ISO)
cytosol  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19946888   PMID:20573744   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Larp4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81765,813,125 - 65,908,920 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1765,830,022 - 65,908,676 (-)EnsemblGRCr8
mRatBN7.21761,138,663 - 61,217,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1764,342,474 - 64,421,256 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01768,345,568 - 68,424,348 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01762,506,614 - 62,585,282 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01763,236,007 - 63,317,298 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1763,265,407 - 63,314,019 (+)Ensemblrn6Rnor6.0
Rnor_5.01765,007,058 - 65,085,258 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41771,931,605 - 72,010,103 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1759,363,334 - 59,441,817 (+)NCBICelera
RGSC_v3.11771,943,684 - 72,020,936 (-)NCBI
Cytogenetic Map17q12.1NCBI
LARP4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810806,914 - 988,341 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10806,915 - 931,821 (-)Ensemblhg38GRCh38
GRCh3710852,854 - 977,645 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610845,484 - 921,702 (-)NCBIBuild 36Build 36hg18NCBI36
Celera10805,808 - 882,035 (-)NCBICelera
Cytogenetic Map10p15.3NCBI
HuRef10792,203 - 916,997 (-)NCBIHuRef
CHM1_110852,377 - 977,610 (-)NCBICHM1_1
T2T-CHM13v2.010804,686 - 932,709 (-)NCBIT2T-CHM13v2.0
Larp4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39139,143,643 - 9,224,487 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl139,143,917 - 9,224,487 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38139,093,653 - 9,174,451 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl139,093,881 - 9,174,451 (+)Ensemblmm10GRCm38
MGSCv37139,093,151 - 9,172,355 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36139,093,151 - 9,172,355 (+)NCBIMGSCv36mm8
Celera139,036,118 - 9,115,259 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map135.0NCBI
Larp4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955492138,374 - 193,145 (+)Ensembl
ChiLan1.0NW_004955492113,900 - 197,753 (+)NCBIChiLan1.0ChiLan1.0
LARP4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2813,330,417 - 13,452,683 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11013,335,739 - 13,457,978 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010842,621 - 966,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110894,957 - 971,160 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10894,957 - 971,154 (-)EnsemblpanPan2panpan1.1
LARP4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1234,026,788 - 34,122,144 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl234,026,534 - 34,119,443 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha231,062,127 - 31,156,072 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0234,411,932 - 34,506,183 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl234,412,588 - 34,506,181 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1231,495,099 - 31,589,276 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0232,334,911 - 32,429,094 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0233,081,930 - 33,176,119 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Larp4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934437,073,263 - 37,137,741 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648413,238,528 - 13,299,448 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648413,238,456 - 13,302,962 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LARP4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11068,621,596 - 68,707,894 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21075,646,959 - 75,711,019 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LARP4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19778,786 - 898,263 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660515,811,979 - 5,950,512 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Larp4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477510,083,476 - 10,145,712 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477510,055,200 - 10,149,178 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Larp4b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11422,986,259 - 23,064,823 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Larp4b
406 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:785
Count of miRNA genes:338
Interacting mature miRNAs:463
Transcripts:ENSRNOT00000058548
Prediction methods:Microtar, Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)173006647275066472Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)173310464578104645Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)172652205171522051Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)173544694975762341Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172201970567019705Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)173310464578104645Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)176109144668550213Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172385892668858926Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172385892668858926Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172723344572233445Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172385892668858926Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172385892668858926Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172385892668858926Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176369714782818564Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat

Markers in Region
D17Rat124  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81765,868,876 - 65,869,010 (+)Marker Load Pipeline
mRatBN7.21761,177,516 - 61,177,650 (-)MAPPERmRatBN7.2
Rnor_6.01763,275,714 - 63,275,847NCBIRnor6.0
Rnor_5.01765,046,765 - 65,046,898UniSTSRnor5.0
RGSC_v3.41771,970,266 - 71,970,400RGDRGSC3.4
RGSC_v3.41771,970,267 - 71,970,400UniSTSRGSC3.4
Celera1759,402,870 - 59,403,009UniSTS
RGSC_v3.11771,981,067 - 71,981,616RGD
SHRSP x BN Map1732.6999UniSTS
SHRSP x BN Map1732.6999RGD
Cytogenetic Map17q12.1UniSTS
RH129270  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21761,138,816 - 61,139,019 (-)MAPPERmRatBN7.2
Rnor_6.01763,316,988 - 63,317,190NCBIRnor6.0
Rnor_5.01765,084,948 - 65,085,150UniSTSRnor5.0
RGSC_v3.41771,931,713 - 71,931,915UniSTSRGSC3.4
Celera1759,441,507 - 59,441,709UniSTS
Cytogenetic Map17q12.1UniSTS
AA849380  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21761,182,962 - 61,183,117 (-)MAPPERmRatBN7.2
Rnor_6.01763,270,247 - 63,270,401NCBIRnor6.0
Rnor_5.01765,041,298 - 65,041,452UniSTSRnor5.0
RGSC_v3.41771,975,713 - 71,975,867UniSTSRGSC3.4
Celera1759,397,403 - 59,397,557UniSTS
RH 3.4 Map17586.2UniSTS
Cytogenetic Map17q12.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010058882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000058548   ⟹   ENSRNOP00000055347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1765,830,022 - 65,908,676 (-)Ensembl
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)Ensembl
Rnor_6.0 Ensembl1763,265,444 - 63,313,864 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077471   ⟹   ENSRNOP00000073054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1765,830,022 - 65,908,676 (-)Ensembl
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)Ensembl
Rnor_6.0 Ensembl1763,265,407 - 63,314,019 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095591   ⟹   ENSRNOP00000091873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1765,830,022 - 65,874,912 (-)Ensembl
mRatBN7.2 Ensembl1761,138,709 - 61,184,498 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120050   ⟹   ENSRNOP00000089771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1765,830,022 - 65,908,676 (-)Ensembl
mRatBN7.2 Ensembl1761,138,709 - 61,187,960 (-)Ensembl
RefSeq Acc Id: NM_001107361   ⟹   NP_001100831
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,022 - 65,908,676 (-)NCBI
mRatBN7.21761,138,663 - 61,217,318 (-)NCBI
Rnor_6.01763,236,007 - 63,317,298 (+)NCBI
Rnor_5.01765,007,058 - 65,085,258 (+)NCBI
RGSC_v3.41771,931,605 - 72,010,103 (-)RGD
Celera1759,363,334 - 59,441,817 (+)RGD
Sequence:
RefSeq Acc Id: XM_039095755   ⟹   XP_038951683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095756   ⟹   XP_038951684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,779 (-)NCBI
mRatBN7.21761,138,709 - 61,217,423 (-)NCBI
RefSeq Acc Id: XM_039095757   ⟹   XP_038951685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095758   ⟹   XP_038951686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095760   ⟹   XP_038951688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095761   ⟹   XP_038951689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095762   ⟹   XP_038951690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095763   ⟹   XP_038951691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_039095764   ⟹   XP_038951692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
mRatBN7.21761,138,709 - 61,217,191 (-)NCBI
RefSeq Acc Id: XM_063276484   ⟹   XP_063132554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,885 (-)NCBI
RefSeq Acc Id: XM_063276485   ⟹   XP_063132555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,920 (-)NCBI
RefSeq Acc Id: XM_063276486   ⟹   XP_063132556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
RefSeq Acc Id: XM_063276487   ⟹   XP_063132557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
RefSeq Acc Id: XM_063276488   ⟹   XP_063132558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
RefSeq Acc Id: XM_063276489   ⟹   XP_063132559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,865 (-)NCBI
RefSeq Acc Id: XM_063276490   ⟹   XP_063132560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,830,068 - 65,908,555 (-)NCBI
RefSeq Acc Id: XR_010058882
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81765,813,125 - 65,908,555 (-)NCBI
RefSeq Acc Id: NP_001100831   ⟸   NM_001107361
- UniProtKB: A6KN12 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073054   ⟸   ENSRNOT00000077471
Ensembl Acc Id: ENSRNOP00000055347   ⟸   ENSRNOT00000058548
RefSeq Acc Id: XP_038951684   ⟸   XM_039095756
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951692   ⟸   XM_039095764
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038951686   ⟸   XM_039095758
- Peptide Label: isoform X3
- UniProtKB: D3ZF45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951691   ⟸   XM_039095763
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038951690   ⟸   XM_039095762
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038951689   ⟸   XM_039095761
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038951688   ⟸   XM_039095760
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038951685   ⟸   XM_039095757
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K4I2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951683   ⟸   XM_039095755
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000091873   ⟸   ENSRNOT00000095591
Ensembl Acc Id: ENSRNOP00000089771   ⟸   ENSRNOT00000120050
RefSeq Acc Id: XP_063132555   ⟸   XM_063276485
- Peptide Label: isoform X4
- UniProtKB: A6KN12 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132554   ⟸   XM_063276484
- Peptide Label: isoform X3
- UniProtKB: D3ZF45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132559   ⟸   XM_063276489
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063132560   ⟸   XM_063276490
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063132558   ⟸   XM_063276488
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063132557   ⟸   XM_063276487
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A8U8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132556   ⟸   XM_063276486
- Peptide Label: isoform X6
Protein Domains
HTH La-type RNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZF45-F1-model_v2 AlphaFold D3ZF45 1-737 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310713 AgrOrtholog
BioCyc Gene G2FUF-8902 BioCyc
Ensembl Genes ENSRNOG00000015888 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058548 ENTREZGENE
  ENSRNOT00000058548.6 UniProtKB/TrEMBL
  ENSRNOT00000077471 ENTREZGENE
  ENSRNOT00000077471.3 UniProtKB/TrEMBL
  ENSRNOT00000095591.2 UniProtKB/TrEMBL
  ENSRNOT00000120050 ENTREZGENE
  ENSRNOT00000120050.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro La_dom_prot UniProtKB/TrEMBL
  LARP5_RRM UniProtKB/TrEMBL
  Lupus_La_RNA-bd UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:307070 UniProtKB/TrEMBL
NCBI Gene 307070 ENTREZGENE
PANTHER LA-RELATED PROTEIN 4B UniProtKB/TrEMBL
  PTHR22792 UniProtKB/TrEMBL
Pfam PF05383 UniProtKB/TrEMBL
PhenoGen Larp4b PhenoGen
PROSITE HTH_LA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015888 RatGTEx
SMART SM00715 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A0G2K4I2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8U8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AUI4_RAT UniProtKB/TrEMBL
  A6KN12 ENTREZGENE, UniProtKB/TrEMBL
  D3ZF45 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Larp4b  La ribonucleoprotein 4B  Larp4b  La ribonucleoprotein domain family, member 4B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-17 Larp4b  La ribonucleoprotein domain family, member 4B  Larp5  La ribonucleoprotein domain family, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Larp5  La ribonucleoprotein domain family, member 5   Larp5_predicted  La ribonucleoprotein domain family, member 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Larp5_predicted  La ribonucleoprotein domain family, member 5 (predicted)  RGD1310713_predicted  similar to expressed sequence AI256361 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1310713_predicted  similar to expressed sequence AI256361 (predicted)  LOC307070_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC307070_predicted  similar to expressed sequence AI256361 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL