Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Zcchc2 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Zcchc2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ZCCHC2 mRNA | CTD | PMID:36331819 | Zcchc2 | Rat | 1,1-dichloroethene | increases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of ZCCHC2 mRNA | CTD | PMID:26682919 | Zcchc2 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Zcchc2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine affects the expression of ZCCHC2 mRNA | CTD | PMID:22206623 | Zcchc2 | Rat | 17beta-estradiol | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ZCCHC2 mRNA | CTD | PMID:20106945|PMID:21632981 | Zcchc2 | Rat | 17beta-estradiol | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of ZCCHC2 mRNA | CTD | PMID:31614463 | Zcchc2 | Rat | 17beta-estradiol | decreases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | Estradiol results in decreased expression of ZCCHC2 mRNA | CTD | PMID:39298647 | Zcchc2 | Rat | 17beta-estradiol | affects expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Estradiol affects the expression of ZCCHC2 mRNA | CTD | PMID:22574217 | Zcchc2 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of ZCCHC2 mRNA | CTD | PMID:29581250 | Zcchc2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZCCHC2 mRNA | CTD | PMID:17337447|PMID:20159946 | Zcchc2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ZCCHC2 mRNA | CTD | PMID:33387578 | Zcchc2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZCCHC2 mRNA | CTD | PMID:20106945|PMID:21632981 | Zcchc2 | Rat | 2-hydroxypropanoic acid | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of ZCCHC2 mRNA | CTD | PMID:30851411 | Zcchc2 | Rat | 2-palmitoylglycerol | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of ZCCHC2 mRNA | CTD | PMID:37199045 | Zcchc2 | Rat | 3-methylcholanthrene | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Methylcholanthrene promotes the reaction [AHR protein binds to ZCCHC2 promoter] | CTD | PMID:20348232 | Zcchc2 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of ZCCHC2 mRNA | CTD | PMID:31881176 | Zcchc2 | Rat | acrylamide | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of ZCCHC2 mRNA | CTD | PMID:32763439 | Zcchc2 | Rat | aflatoxin B1 | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ZCCHC2 mRNA | CTD | PMID:21641981 | Zcchc2 | Rat | aflatoxin B1 | decreases methylation | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ZCCHC2 gene | CTD | PMID:27153756 | Zcchc2 | Rat | all-trans-retinoic acid | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ZCCHC2 mRNA | CTD | PMID:33167477 | Zcchc2 | Rat | aristolochic acid A | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ZCCHC2 mRNA | CTD | PMID:33212167 | Zcchc2 | Rat | arsane | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Arsenic results in increased expression of ZCCHC2 mRNA | CTD | PMID:19945496 | Zcchc2 | Rat | arsenic atom | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Arsenic results in increased expression of ZCCHC2 mRNA | CTD | PMID:19945496 | Zcchc2 | Rat | arsenite(3-) | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ZCCHC2 mRNA] | CTD | PMID:32406909 | Zcchc2 | Rat | benzene | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Benzene results in increased expression of ZCCHC2 mRNA | CTD | PMID:20359517 | Zcchc2 | Rat | benzo[a]pyrene | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ZCCHC2 mRNA | CTD | PMID:22316170 | Zcchc2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZCCHC2 mRNA | CTD | PMID:19150397|PMID:20018196 | Zcchc2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ZCCHC2 mRNA | CTD | PMID:32145629 | Zcchc2 | Rat | bisphenol A | increases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ZCCHC2 mRNA | CTD | PMID:33221593 | Zcchc2 | Rat | bortezomib | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of ZCCHC2 mRNA | CTD | PMID:20977926 | Zcchc2 | Rat | butanal | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of ZCCHC2 mRNA | CTD | PMID:26079696 | Zcchc2 | Rat | cadmium atom | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZCCHC2 more ... | CTD | PMID:35301059 | Zcchc2 | Rat | cadmium atom | multiple interactions | ISO | Zcchc2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZCCHC2 more ... | CTD | PMID:28111341|PMID:37236586 | Zcchc2 | Rat | cadmium dichloride | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZCCHC2 more ... | CTD | PMID:35301059 | Zcchc2 | Rat | cadmium dichloride | multiple interactions | ISO | Zcchc2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZCCHC2 more ... | CTD | PMID:28111341|PMID:37236586 | Zcchc2 | Rat | caffeine | decreases phosphorylation | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ZCCHC2 protein | CTD | PMID:35688186 | Zcchc2 | Rat | carbamazepine | affects expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of ZCCHC2 mRNA | CTD | PMID:25979313 | Zcchc2 | Rat | carbon nanotube | increases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of ZCCHC2 mRNA | CTD | PMID:25554681 | Zcchc2 | Rat | CGP 52608 | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ZCCHC2 gene] | CTD | PMID:28238834 | Zcchc2 | Rat | cisplatin | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ZCCHC2 mRNA | CTD | PMID:27392435 | Zcchc2 | Rat | copper(II) sulfate | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ZCCHC2 mRNA | CTD | PMID:19549813 | Zcchc2 | Rat | cyclosporin A | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ZCCHC2 mRNA | CTD | PMID:21632981|PMID:25562108 | Zcchc2 | Rat | dibenz[a,h]anthracene | increases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | 1,2,5,6-dibenzanthracene results in increased expression of ZCCHC2 mRNA | CTD | PMID:26377693 | Zcchc2 | Rat | dichloromethane | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Methylene Chloride results in increased expression of ZCCHC2 mRNA | CTD | PMID:20359517 | Zcchc2 | Rat | dimethylarsinous acid | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | dimethylarsinous acid results in increased expression of ZCCHC2 mRNA | CTD | PMID:19945496 | Zcchc2 | Rat | doxorubicin | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ZCCHC2 mRNA | CTD | PMID:29803840 | Zcchc2 | Rat | elemental selenium | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of ZCCHC2 mRNA | CTD | PMID:19244175 | Zcchc2 | Rat | elemental selenium | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Selenium results in decreased expression of ZCCHC2 mRNA | CTD | PMID:19244175 | Zcchc2 | Rat | ethyl methanesulfonate | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of ZCCHC2 mRNA | CTD | PMID:23649840 | Zcchc2 | Rat | ethylbenzene | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | ethylbenzene results in increased expression of ZCCHC2 mRNA | CTD | PMID:20359517 | Zcchc2 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of ZCCHC2 mRNA | CTD | PMID:24793618 | Zcchc2 | Rat | formaldehyde | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ZCCHC2 mRNA | CTD | PMID:20655997|PMID:23649840 | Zcchc2 | Rat | FR900359 | increases phosphorylation | ISO | ZCCHC2 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of ZCCHC2 protein | CTD | PMID:37730182 | Zcchc2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ZCCHC2 mRNA | CTD | PMID:33387578 | Zcchc2 | Rat | hydrogen peroxide | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in decreased expression of ZCCHC2 mRNA | CTD | PMID:18951874 | Zcchc2 | Rat | inulin | multiple interactions | ISO | Zcchc2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ZCCHC2 mRNA | CTD | PMID:36331819 | Zcchc2 | Rat | lead diacetate | increases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | lead acetate results in increased expression of ZCCHC2 mRNA | CTD | PMID:21829687 | Zcchc2 | Rat | methyl methanesulfonate | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of ZCCHC2 mRNA | CTD | PMID:23649840 | Zcchc2 | Rat | o-xylene | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | 2-xylene results in increased expression of ZCCHC2 mRNA | CTD | PMID:20359517 | Zcchc2 | Rat | okadaic acid | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of ZCCHC2 mRNA | CTD | PMID:38832940 | Zcchc2 | Rat | paracetamol | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ZCCHC2 mRNA | CTD | PMID:21420995 | Zcchc2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ZCCHC2 mRNA | CTD | PMID:33387578 | Zcchc2 | Rat | pentachlorophenol | increases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of ZCCHC2 mRNA | CTD | PMID:23892564 | Zcchc2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Zcchc2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ZCCHC2 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Zcchc2 | Rat | quercetin | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of ZCCHC2 mRNA | CTD | PMID:21632981 | Zcchc2 | Rat | rac-lactic acid | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of ZCCHC2 mRNA | CTD | PMID:30851411 | Zcchc2 | Rat | selenium atom | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of ZCCHC2 mRNA | CTD | PMID:19244175 | Zcchc2 | Rat | selenium atom | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Selenium results in decreased expression of ZCCHC2 mRNA | CTD | PMID:19244175 | Zcchc2 | Rat | serpentine asbestos | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Asbestos, Serpentine results in increased expression of ZCCHC2 mRNA | CTD | PMID:21148743 | Zcchc2 | Rat | succimer | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ZCCHC2 mRNA | CTD | PMID:26378955 | Zcchc2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ZCCHC2 mRNA | CTD | PMID:34492290 | Zcchc2 | Rat | thiram | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Thiram results in increased expression of ZCCHC2 mRNA | CTD | PMID:38568856 | Zcchc2 | Rat | titanium dioxide | decreases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ZCCHC2 mRNA | CTD | PMID:29264374 | Zcchc2 | Rat | titanium dioxide | decreases methylation | ISO | Zcchc2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of ZCCHC2 promoter | CTD | PMID:35295148 | Zcchc2 | Rat | titanium dioxide | increases methylation | ISO | Zcchc2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of ZCCHC2 gene | CTD | PMID:35295148 | Zcchc2 | Rat | toluene | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Toluene results in increased expression of ZCCHC2 mRNA | CTD | PMID:20359517 | Zcchc2 | Rat | trichloroethene | increases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Trichloroethylene results in increased expression of ZCCHC2 mRNA | CTD | PMID:20359517 | Zcchc2 | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of ZCCHC2 mRNA | CTD | PMID:29024780 | Zcchc2 | Rat | tungsten | decreases expression | ISO | Zcchc2 (Mus musculus) | 6480464 | Tungsten results in decreased expression of ZCCHC2 mRNA | CTD | PMID:30912803 | Zcchc2 | Rat | urethane | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of ZCCHC2 mRNA | CTD | PMID:28818685 | Zcchc2 | Rat | valproic acid | affects expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ZCCHC2 mRNA | CTD | PMID:25979313 | Zcchc2 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of ZCCHC2 mRNA | CTD | PMID:23034163 | Zcchc2 | Rat | vincristine | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of ZCCHC2 mRNA | CTD | PMID:23649840 | Zcchc2 | Rat | vitamin E | decreases expression | ISO | ZCCHC2 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of ZCCHC2 mRNA | CTD | PMID:19244175 | Zcchc2 | Rat | vitamin E | multiple interactions | ISO | ZCCHC2 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of ZCCHC2 mRNA | CTD | PMID:19244175 | | 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