Oxsr1 (oxidative stress responsive kinase 1) - Rat Genome Database

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Gene: Oxsr1 (oxidative stress responsive kinase 1) Rattus norvegicus
Analyze
Symbol: Oxsr1
Name: oxidative stress responsive kinase 1
RGD ID: 1310466
Description: Enables protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to osmotic stress; chemokine-mediated signaling pathway; and positive regulation of T cell chemotaxis. Predicted to act upstream of or within cell volume homeostasis; potassium ion transmembrane transport; and renal sodium ion absorption. Predicted to be active in cytosol. Orthologous to human OXSR1 (oxidative stress responsive kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC316064; Osr1; oxidative-stress responsive 1; serine/threonine-protein kinase OSR1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88127,850,481 - 127,941,518 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8127,850,484 - 127,939,750 (-)EnsemblGRCr8
mRatBN7.28118,972,754 - 119,062,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8118,972,754 - 119,062,027 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8124,554,616 - 124,644,062 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08122,753,635 - 122,843,081 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08120,586,701 - 120,676,604 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08127,920,349 - 128,009,951 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8127,920,349 - 128,009,951 (-)Ensemblrn6Rnor6.0
Rnor_5.08127,127,110 - 127,216,712 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48124,196,599 - 124,286,647 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8118,123,990 - 118,213,225 (-)NCBICelera
RGSC_v3.18124,217,575 - 124,306,410 (-)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
hypertension  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
cadmium sulfide  (ISO)
caffeine  (EXP)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
dactolisib  (ISO)
decabromodiphenyl ether  (ISO)
Dibutyl phosphate  (ISO)
divanadium pentaoxide  (ISO)
eplerenone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (EXP)
hexadecanoic acid  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
methapyrilene  (ISO)
methimazole  (EXP)
methoxyacetic acid  (EXP)
methylmercury chloride  (EXP)
Monobutylphthalate  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP)
phenobarbital  (EXP)
pirinixic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sulfadimethoxine  (EXP)
thiram  (ISO)
trimellitic anhydride  (ISO)
tungsten  (ISO)
zearalenone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Taurine inhibits K+-Cl- cotransporter KCC2 to regulate embryonic Cl- homeostasis via with-no-lysine (WNK) protein kinase signaling pathway. Inoue K, etal., J Biol Chem. 2012 Jun 15;287(25):20839-50. doi: 10.1074/jbc.M111.319418. Epub 2012 Apr 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases. Vitari AC, etal., Biochem J. 2005 Oct 1;391(Pt 1):17-24.
Additional References at PubMed
PMID:12386165   PMID:14707132   PMID:16669787   PMID:16832045   PMID:19056867   PMID:22052202   PMID:24393035   PMID:25515571   PMID:27400149   PMID:31362998   PMID:31954517  


Genomics

Comparative Map Data
Oxsr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88127,850,481 - 127,941,518 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8127,850,484 - 127,939,750 (-)EnsemblGRCr8
mRatBN7.28118,972,754 - 119,062,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8118,972,754 - 119,062,027 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8124,554,616 - 124,644,062 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08122,753,635 - 122,843,081 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08120,586,701 - 120,676,604 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08127,920,349 - 128,009,951 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8127,920,349 - 128,009,951 (-)Ensemblrn6Rnor6.0
Rnor_5.08127,127,110 - 127,216,712 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48124,196,599 - 124,286,647 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8118,123,990 - 118,213,225 (-)NCBICelera
RGSC_v3.18124,217,575 - 124,306,410 (-)NCBI
Cytogenetic Map8q32NCBI
OXSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38338,164,063 - 38,255,484 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl338,165,089 - 38,255,484 (+)Ensemblhg38GRCh38
GRCh37338,207,028 - 38,296,975 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,182,030 - 38,271,983 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34338,182,029 - 38,271,979NCBI
Celera338,142,644 - 38,232,606 (+)NCBICelera
Cytogenetic Map3p22.2NCBI
HuRef338,248,039 - 38,338,925 (+)NCBIHuRef
CHM1_1338,158,703 - 38,248,663 (+)NCBICHM1_1
T2T-CHM13v2.0338,170,735 - 38,261,199 (+)NCBIT2T-CHM13v2.0
Oxsr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,067,498 - 119,154,475 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9119,067,498 - 119,151,493 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm389119,238,432 - 119,322,684 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,238,432 - 119,322,427 (-)Ensemblmm10GRCm38
MGSCv379119,149,784 - 119,213,966 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369119,087,131 - 119,171,125 (-)NCBIMGSCv36mm8
Celera9119,708,063 - 119,774,018 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map971.33NCBI
Oxsr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542725,575,655 - 25,696,356 (+)Ensembl
ChiLan1.0NW_00495542725,575,655 - 25,696,356 (+)NCBIChiLan1.0ChiLan1.0
OXSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2238,115,759 - 38,209,133 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1338,120,761 - 38,213,897 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0338,063,299 - 38,153,609 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1338,345,491 - 38,436,279 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl338,345,504 - 38,436,275 (+)EnsemblpanPan2panpan1.1
OXSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1237,931,636 - 8,026,591 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl237,932,254 - 8,024,323 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha237,973,576 - 8,067,716 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0238,221,226 - 8,313,574 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl238,221,839 - 8,315,902 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1238,035,117 - 8,130,106 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0238,175,999 - 8,270,428 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0238,168,533 - 8,263,795 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Oxsr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118194,421,183 - 194,519,453 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647327,559,752 - 27,658,329 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647327,559,756 - 27,658,299 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OXSR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1323,020,530 - 23,116,958 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11323,020,839 - 23,116,957 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21325,225,156 - 25,288,185 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OXSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1151,164,529 - 1,255,935 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl151,164,528 - 1,255,925 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660639,895,779 - 9,985,796 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Oxsr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247312,703,301 - 2,826,419 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247312,703,295 - 2,825,017 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Oxsr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18110,469,433 - 110,558,904 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:363
Count of miRNA genes:217
Interacting mature miRNAs:265
Transcripts:ENSRNOT00000018056
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat

Markers in Region
D8Got351  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,056,955 - 119,057,094 (+)MAPPERmRatBN7.2
Rnor_6.08128,004,880 - 128,005,018NCBIRnor6.0
Rnor_5.08127,211,641 - 127,211,779UniSTSRnor5.0
RGSC_v3.48124,281,577 - 124,281,715UniSTSRGSC3.4
Celera8118,208,155 - 118,208,293UniSTS
Cytogenetic Map8q32UniSTS
RH130404  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28118,972,931 - 118,973,114 (+)MAPPERmRatBN7.2
Rnor_6.08127,920,527 - 127,920,709NCBIRnor6.0
Rnor_5.08127,127,288 - 127,127,470UniSTSRnor5.0
RGSC_v3.48124,196,777 - 124,196,959UniSTSRGSC3.4
Celera8118,124,168 - 118,124,350UniSTS
RH 3.4 Map81302.4UniSTS
Cytogenetic Map8q32UniSTS
RH132547  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,062,968 - 119,063,160 (+)MAPPERmRatBN7.2
Rnor_6.08128,010,892 - 128,011,083NCBIRnor6.0
Rnor_5.08127,217,653 - 127,217,844UniSTSRnor5.0
RGSC_v3.48124,287,588 - 124,287,779UniSTSRGSC3.4
Celera8118,214,166 - 118,214,357UniSTS
RH 3.4 Map81288.5UniSTS
Cytogenetic Map8q32UniSTS
RH143190  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,037,457 - 119,037,569 (+)MAPPERmRatBN7.2
Rnor_6.08127,985,006 - 127,985,117NCBIRnor6.0
Rnor_5.08127,191,767 - 127,191,878UniSTSRnor5.0
RGSC_v3.48124,262,083 - 124,262,194UniSTSRGSC3.4
Celera8118,188,661 - 118,188,772UniSTS
RH 3.4 Map81312.6UniSTS
Cytogenetic Map8q32UniSTS
RH139291  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28119,037,318 - 119,037,445 (+)MAPPERmRatBN7.2
Rnor_6.08127,984,867 - 127,984,993NCBIRnor6.0
Rnor_5.08127,191,628 - 127,191,754UniSTSRnor5.0
RGSC_v3.48124,261,944 - 124,262,070UniSTSRGSC3.4
Celera8118,188,522 - 118,188,648UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018056   ⟹   ENSRNOP00000018056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8127,850,484 - 127,939,750 (-)Ensembl
mRatBN7.2 Ensembl8118,972,754 - 119,062,027 (-)Ensembl
Rnor_6.0 Ensembl8127,920,349 - 128,009,951 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099478   ⟹   ENSRNOP00000079676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8127,850,484 - 127,939,750 (-)Ensembl
mRatBN7.2 Ensembl8118,972,754 - 119,062,027 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108136   ⟹   ENSRNOP00000085510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8127,850,484 - 127,939,579 (-)Ensembl
mRatBN7.2 Ensembl8118,972,764 - 119,044,576 (-)Ensembl
RefSeq Acc Id: NM_001108194   ⟹   NP_001101664
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88127,850,484 - 127,939,750 (-)NCBI
mRatBN7.28118,972,754 - 119,062,027 (-)NCBI
Rnor_6.08127,920,349 - 128,009,951 (-)NCBI
Rnor_5.08127,127,110 - 127,216,712 (-)NCBI
RGSC_v3.48124,196,599 - 124,286,647 (-)RGD
Celera8118,123,990 - 118,213,225 (-)RGD
Sequence:
RefSeq Acc Id: XM_063265654   ⟹   XP_063121724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88127,850,481 - 127,941,518 (-)NCBI
RefSeq Acc Id: XM_063265655   ⟹   XP_063121725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88127,879,805 - 127,941,518 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101664 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121724 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121725 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A0A8I5ZNK2 (Get FASTA)   NCBI Sequence Viewer  
  EDL76918 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018056
  ENSRNOP00000079676.1
RefSeq Acc Id: NP_001101664   ⟸   NM_001108194
- UniProtKB: A0A8I5ZZD5 (UniProtKB/Swiss-Prot),   D3ZUC9 (UniProtKB/TrEMBL),   A6I3V9 (UniProtKB/TrEMBL),   A0A8I5ZNK2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018056   ⟸   ENSRNOT00000018056
Ensembl Acc Id: ENSRNOP00000079676   ⟸   ENSRNOT00000099478
Ensembl Acc Id: ENSRNOP00000085510   ⟸   ENSRNOT00000108136
RefSeq Acc Id: XP_063121724   ⟸   XM_063265654
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZD5 (UniProtKB/Swiss-Prot),   A0A8I5ZNK2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063121725   ⟸   XM_063265655
- Peptide Label: isoform X2
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUC9-F1-model_v2 AlphaFold D3ZUC9 1-527 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696368
Promoter ID:EPDNEW_R6893
Type:initiation region
Name:Oxsr1_1
Description:oxidative-stress responsive 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08128,009,916 - 128,009,976EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310466 AgrOrtholog
BioCyc Gene G2FUF-28795 BioCyc
Ensembl Genes ENSRNOG00000013136 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018056 ENTREZGENE
  ENSRNOT00000099478.1 UniProtKB/Swiss-Prot
Gene3D-CATH Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
  Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Kinase_OSR1/WNK_CCT UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  STE20/SPS1-PAK UniProtKB/Swiss-Prot
NCBI Gene 316064 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE OSR1 UniProtKB/Swiss-Prot
  STERILE20-LIKE KINASE, ISOFORM B-RELATED UniProtKB/Swiss-Prot
Pfam OSR1_C UniProtKB/Swiss-Prot
  Pkinase UniProtKB/Swiss-Prot
PhenoGen Oxsr1 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013136 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP Protein kinase-like (PK-like) UniProtKB/Swiss-Prot
UniProt A0A8I5ZNK2 ENTREZGENE
  A0A8I5ZZD5 ENTREZGENE
  A0A9T0CD43_RAT UniProtKB/TrEMBL
  A6I3V9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUC9 ENTREZGENE, UniProtKB/TrEMBL
  OXSR1_RAT UniProtKB/Swiss-Prot
UniProt Secondary A0A8I5ZZD5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-01 Oxsr1  oxidative stress responsive kinase 1  Oxsr1  oxidative-stress responsive 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Oxsr1  oxidative-stress responsive 1   Oxsr1_predicted  oxidative-stress responsive 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Oxsr1_predicted  oxidative-stress responsive 1 (predicted)      Symbol and Name updated 1299863 APPROVED
2006-03-28 Oxsr1_predicted    Osr1_predicted  oxidative-stress responsive 1 (predicted)  Symbol updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-01-12 Osr1_predicted  oxidative-stress responsive 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED